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Information on EC 2.3.1.B40 - caliceamicin oktaketide synthase

for references in articles please use BRENDA:EC2.3.1.B40
preliminary BRENDA-supplied EC number
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Word Map
  • 2.3.1.B40
  • calicheamicins
  • thioesterase
  • micromonospora
  • iterative
  • polyene
  • 9-membered
  • dynemicin
  • octaketide
  • echinospora
  • actinomycete
  • neocarzinostatin
The expected taxonomic range for this enzyme is: Micromonospora echinospora
Synonyms
cale8, enediyne polyketide synthase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
8 malonyl-CoA + NADPH + H+ = 8 CoA + (4E,6E,8E,10E,12E,14E)-3-hydroxyhexadeca-4,6,8,10,12,14-hexaenoic acid + 8 CO2 + NADP+ + H2O
show the reaction diagram
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