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Reference on EC 2.3.1.39 - [acyl-carrier-protein] S-malonyltransferase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Chohnan, S.; Fujio, T.; Takaki, T.; Yonekura, M.; Nishihara, H.; Takamura, Y.
Malonate decarboxylase of Pseudomonas putida is composed of five subunits
FEMS Microbiol. Lett.
169
37-43
1998
Pseudomonas putida (Q9Z447), Pseudomonas putida
Manually annotated by BRENDA team
Shimakata, T.; Stumpf, P.K.
The procaryotic nature of the fatty acid synthetase of developing Carthamus tinctorius L. (Safflower) seeds
Arch. Biochem. Biophys.
217
144-154
1982
Carthamus tinctorius
Manually annotated by BRENDA team
Shimakata, T.; Stumpf, P.K.
The purification and function of acetyl coenzyme A:acyl carrier protein transacylase
J. Biol. Chem.
258
3592-3598
1983
Brassica juncea, Carthamus tinctorius, Cuphea lutea, Pisum sativum, Spinacia oleracea
Manually annotated by BRENDA team
Hendren, R.W.; Bloch, K.
Fatty acid synthetases from Euglena gracilis. Separation of component activities of the ACP-dependent fatty acid synthetase and partial purification of the beta-ketoacyl-ACP synthetase
J. Biol. Chem.
255
1504-1508
1980
Euglena gracilis, Euglena gracilis Z
Manually annotated by BRENDA team
Caughey, I.; Kekwick, R.G.O.
The characteristics of some components of the fatty acid synthetase system in the plastids from the mesocarp of avocado (Persea americana) fruit
Eur. J. Biochem.
123
553-561
1982
Persea americana
Manually annotated by BRENDA team
Vagelos, R.P.
Acyl group transfer (acyl carrier protein)
The Enzymes, 3rd Ed. (Boyer, P. D. , ed. )
8
155-199
1973
Escherichia coli
-
Manually annotated by BRENDA team
Prescott, D.J.; Vagelos, P.R.
Acyl carrier protein
Adv. Enzymol. Relat. Areas Mol. Biol.
36
269-311
1972
Escherichia coli
Manually annotated by BRENDA team
Williamson, I.P.; Wakil, S.J.
Studies on the mechanism of fatty acid synthesis. XVII. Preparation and general properties of acetyl coenzyme A and malonyl coenzyme A-acyl carrier protein transacylases
J. Biol. Chem.
241
2326-2332
1966
Escherichia coli
Manually annotated by BRENDA team
Rangan, V.S.; Smith, S.
Alteration of the substrate specificity of the malonyl-CoA/acetyl-CoA:acyl carrier protein S-acyltransferase domain of the multifunctional fatty acid synthase by mutation of a single arginine residue
J. Biol. Chem.
272
11975-11978
1997
Rattus norvegicus
Manually annotated by BRENDA team
Alberts, A.W.; Majerus, P.W.; Vagelos, P.R.
Malonyl-CoA acyl carrier protein transacylase
Methods Enzymol.
14
53-56
1969
Escherichia coli
-
Manually annotated by BRENDA team
Joshi, V.C.
Mechanism of malonyl-coenzyme A-acyl carrier protein transacylase
Biochem. J.
128
43P-44P
1972
Escherichia coli
Manually annotated by BRENDA team
Ruch, F.E.; Vagelos, P.R.
The isolation and general properties of Escherichia coli malonyl coenzyme A-acyl carrier protein transacylase
J. Biol. Chem.
248
8086-8094
1973
Escherichia coli
Manually annotated by BRENDA team
Ruch, F.E.; Vagelos, P.R.
Characterization of a malonyl-enzyme intermediate and identification of the malonyl binding site in malonyl coenzyme A-acyl carrier protein transacylase of Escherichia coli
J. Biol. Chem.
248
8095-8106
1973
Escherichia coli
Manually annotated by BRENDA team
Verwoert, I.I.G.S.; Verbree, E.C.; VanDerLinden, K.H.; Nijkamp, H.J.J.; Stuitje, A.R.
Cloning, nucleotide sequence, and expression of the Escherichia coli fabD gene, encoding malonyl coenzyme A-acyl carrier protein transacylase
J. Bacteriol.
174
2851-2857
1992
Escherichia coli
Manually annotated by BRENDA team
Magnuson, K.; Oh, W.; Larson, T.J.; Cronan, J.E.
Cloning and nucleotide sequence of the fabD gene encoding malonyl coenzyme A-acyl carrier protein transacylase of Escherichia coli
FEBS Lett.
299
262-266
1992
Escherichia coli
Manually annotated by BRENDA team
Stapleton, S.R.; Jaworski, J.G.
Characterization and purification of malonyl-coenzyme A:[acyl-carrier protein] transacylases from spinach and Anabaena variabilis
Biochim. Biophys. Acta
794
240-248
1984
Trichormus variabilis, Spinacia oleracea
-
Manually annotated by BRENDA team
Guerra, D.J.; Ohlrogge, J.B.
Partial purification and characterization of two forms of malonyl-coenzyme A:acyl carrier protein transacylase from soybean leaf tissue
Arch. Biochem. Biophys.
246
274-285
1986
Escherichia coli, Glycine max
Manually annotated by BRENDA team
Szafranska, A.E.; Hitchman, T.S.; Cox, R.J.; Crosby, J.; Simpson, T.J.
Kinetic and mechanistic analysis of the malonyl CoA:ACP transacylase from Streptomyces coelicolor indicates a single catalytically competent serine nucleophile at the active site
Biochemistry
41
1421-1427
2002
Escherichia coli, Streptomyces coelicolor
Manually annotated by BRENDA team
Kremer, L.; Nampoothiri, K.M.; Lesjean, S.; Dover, L.G.; Graham, S.; Betts, J.; Brennan, P.J.; Minnikin, D.E.; Locht, C.; Besra, G.S.
Biochemical characterization of acyl carrier protein (AcpM) and malonyl-CoA:AcpM transacylase (mtFabD), two major components of Mycobacterium tuberculosis fatty acid synthase II
J. Biol. Chem.
276
27967-27974
2001
Mycobacterium tuberculosis
Manually annotated by BRENDA team
Dreier, J.; Li, Q.; Khosla, C.
Malonyl-CoA:ACP transacylase from Streptomyces coelicolor has two alternative catalytically active nucleophiles
Biochemistry
40
12407-12411
2001
Escherichia coli, Streptomyces coelicolor
Manually annotated by BRENDA team
Taguchi, K.; Aoyagi, Y.; Matsusaki, H.; Fukui, T.; Doi, Y.
Over-expression of 3-ketoacyl-ACP synthase III or malonyl-CoA-ACP transacylase gene induces monomer supply for polyhydroxybutyrate production in Escherichia coli HB101
Biotechnol. Lett.
21
579-584
1999
Escherichia coli, Pseudomonas sp. (Q9WXI0)
-
Manually annotated by BRENDA team
Kutchma, A.J.; Hoang, T.T.; Schweizer, H.P.
Characterization of a Pseudomonas aeruginosa fatty acid biosynthetic gene cluster: purification of acyl carrier protein (ACP) and malonyl-coenzyme A:ACP transacylase (FabD)
J. Bacteriol.
181
5498-5504
1999
Escherichia coli, Pseudomonas aeruginosa
Manually annotated by BRENDA team
Rangan, V.S.; Serre, L.; Witkowska, H.E.; Bari, A.; Smith, S.
Characterization of the malonyl-/acetyltransacylase domain of the multifunctional animal fatty acid synthase by expression in Escherichia coli and refolding in vitro
Protein Eng.
10
561-566
1997
Rattus norvegicus
Manually annotated by BRENDA team
Summers, R.G.; Ali, A.; Shen, B.; Wessel, W.A.; Hutchinson, C.R.
Malonyl-coenzyme A:acyl carrier protein acyltransferase of Streptomyces glaucescens: a possible link between fatty acid and polyketide biosynthesis
Biochemistry
34
9389-9402
1995
Streptomyces glaucescens
Manually annotated by BRENDA team
Serre, L.; Verbree, E.C.; Dauter, Z.; Stuitje, A.R.; Derewenda, Z.S.
The Escherichia coli malonyl-CoA:acyl carrier protein transacylase at 1.5-.ANG. resolution
J. Biol. Chem.
270
12961-12964
1995
Escherichia coli
Manually annotated by BRENDA team
Verwoert, II; Verhagen, E.F.; van der Linden, K.H.; Verbree, E.C.; Nijkamp, H.J.; Stuitje, A.R.
Molecular characterization of an Escherichia coli mutant with a temperature-sensitive malonyl coenzyme A-acyl carrier protein transacylase
FEBS Lett.
348
311-316
1994
Escherichia coli
Manually annotated by BRENDA team
Zhang, L.; Joshi, A.K.; Hofmann, J.; Schweizer, E.; Smith, S.
Cloning, expression, and characterization of the human mitochondrial beta-ketoacyl synthase. Complementation of the yeast CEM1 knock-out strain
J. Biol. Chem.
280
12422-12429
2005
Homo sapiens
Manually annotated by BRENDA team
Molnos, J.; Gardiner, R.; Dale, G.E.; Lange, R.
A continuous coupled enzyme assay for bacterial malonyl-CoA:acyl carrier protein transacylase (FabD)
Anal. Biochem.
319
171-176
2003
Escherichia coli K-12
Manually annotated by BRENDA team
Koppisch, A.T.; Khosla, C.
Structure-based mutagenesis of the malonyl-CoA:acyl carrier protein transacylase from Streptomyces coelicolor
Biochemistry
42
11057-11064
2003
Streptomyces coelicolor
Manually annotated by BRENDA team
Prigge, S.T.; He, X.; Gerena, L.; Waters, N.C.; Reynolds, K.A.
The initiating steps of a type II fatty acid synthase in Plasmodium falciparum are catalyzed by pfACP, pfMCAT, and pfKASIII
Biochemistry
42
1160-1169
2003
Plasmodium falciparum
Manually annotated by BRENDA team
Kumar, P.; Koppisch, A.T.; Cane, D.E.; Khosla, C.
Enhancing the modularity of the modular polyketide synthases: transacylation in modular polyketide synthases catalyzed by malonyl-CoA:ACP transacylase
J. Am. Chem. Soc.
125
14307-14312
2003
Streptomyces coelicolor
Manually annotated by BRENDA team
Sinha, I.; Dick, T.
Role for malonyl coenzyme A:acyl carrier protein transacylase (MCAT) in the growth-inhibitory effect of the calmodulin antagonist trifluoperazine in Mycobacterium bovis BCG
J. Antimicrob. Chemother.
53
1072-1075
2004
Mycobacterium tuberculosis variant bovis
Manually annotated by BRENDA team
Keatinge-Clay, A.T.; Shelat, A.A.; Savage, D.F.; Tsai, S.C.; Miercke, L.J.; O'Connell, J.D., 3rd; Khosla, C.; Stroud, R.M.
Catalysis, specificity, and ACP docking site of Streptomyces coelicolor malonyl-CoA:ACP transacylase
Structure
11
147-154
2003
Streptomyces coelicolor
Manually annotated by BRENDA team
Oefner, C.; Schulz, H.; DArcy, A.; Dale, G.E.
Mapping the active site of Escherichia coli malonyl-CoA-acyl carrier protein transacylase (FabD) by protein crystallography
Acta Crystallogr. Sect. D
D62
613-618
2006
Escherichia coli
Manually annotated by BRENDA team
Arthur, C.J.; Szafranska, A.E.; Long, J.; Mills, J.; Cox, R.J.; Findlow, S.C.; Simpson, T.J.; Crump, M.P.; Crosby, J.
The malonyl transferase activity of type II polyketide synthase acyl carrier proteins
Chem. Biol.
13
587-596
2006
Streptomyces coelicolor
Manually annotated by BRENDA team
Huang, Y.S.; Ge, J.; Zhang, H.M.; Lei, J.Q.; Zhang, X.L.; Wang, H.H.
Purification and characterization of the Mycobacterium tuberculosis FabD2, a novel malonyl-CoA:AcpM transacylase of fatty acid synthase
Protein Expr. Purif.
45
393-399
2006
Mycobacterium tuberculosis
Manually annotated by BRENDA team
Ghadbane, H.; Brown, A.K.; Kremer, L.; Besra, G.S.; Fuetterer, K.
Structure of Mycobacterium tuberculosis mtFabD, a malonyl-CoA:acyl carrier protein transacylase (MCAT)
Acta Crystallogr. Sect. F
F63
831-835
2007
Mycobacterium tuberculosis (P9WNG5), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WNG5)
Manually annotated by BRENDA team
Hoenke, S.; Dimroth, P.
Formation of catalytically active acetyl-S-malonate decarboxylase requires malonyl-coenzyme A:acyl carrier protein transacylase as auxiliary enzyme [corrected]
Eur. J. Biochem.
259
181-187
1999
Klebsiella pneumoniae (O32717), Klebsiella pneumoniae
Manually annotated by BRENDA team
Li, Z.; Huang, Y.; Ge, J.; Fan, H.; Zhou, X.; Li, S.; Bartlam, M.; Wang, H.; Rao, Z.
The crystal structure of MCAT from Mycobacterium tuberculosis reveals three new catalytic models
J. Mol. Biol.
371
1075-1083
2007
Mycobacterium tuberculosis (P9WNG5), Mycobacterium tuberculosis H37Rv (P9WNG5)
Manually annotated by BRENDA team
Zhang, L.; Liu, W.; Xiao, J.; Hu, T.; Chen, J.; Chen, K.; Jiang, H.; Shen, X.
Malonyl-CoA: acyl carrier protein transacylase from Helicobacter pylori: Crystal structure and its interaction with acyl carrier protein
Protein Sci.
16
1184-1192
2007
Helicobacter pylori (Q56S05), Helicobacter pylori
Manually annotated by BRENDA team
Arthur, C.J.; Williams, C.; Pottage, K.; Ploskon, E.; Findlow, S.C.; Burston, S.G.; Simpson, T.J.; Crump, M.P.; Crosby, J.
Structure and malonyl CoA-ACP transacylase binding of Streptomyces coelicolor fatty acid synthase acyl carrier protein
ACS Chem. Biol.
4
625-636
2009
Streptomyces coelicolor
Manually annotated by BRENDA team
Jung, J.W.; Natarajan, S.; Kim, H.; Ahn, Y.J.; Kim, S.; Kim, J.G.; Lee, B.M.; Kang, L.W.
Cloning, expression, crystallization and preliminary X-ray crystallographic analysis of malonyl-CoA-acyl carrier protein transacylase (FabD) from Xanthomonas oryzae pv. oryzae
Acta Crystallogr. Sect. F
64
1143-1145
2008
Xanthomonas oryzae (Q5H4I7), Xanthomonas oryzae
Manually annotated by BRENDA team
Hong, S.K.; Kim, K.H.; Kim, E.E.
Cloning, purification, crystallization and preliminary X-ray crystallographic analysis of MCAT from Staphylococcus aureus
Acta Crystallogr. Sect. F
66
20-22
2010
Staphylococcus aureus (Q99UN8), Staphylococcus aureus
Manually annotated by BRENDA team
Gurvitz, A.
Physiological function of mycobacterial mtFabD, an essential malonyl-CoA:AcpM transacylase of type 2 fatty acid synthase FASII, in yeast mct1Delta Cells
Comp. Funct. Genomics
2009
836172
2009
Mycobacterium tuberculosis
Manually annotated by BRENDA team
Misra, A.; Surolia, N.; Surolia, A
Catalysis and mechanism of malonyl transferase activity in type II fatty acid biosynthesis acyl carrier proteins
Mol. Biosyst.
5
651-659
2009
Escherichia coli, Plasmodium falciparum
Manually annotated by BRENDA team
Zhang, X.; Agrawal, A.; San, K.Y.
Improving fatty acid production in Escherichia coli through the overexpression of malonyl coA-acyl carrier protein transacylase
Biotechnol. Prog.
28
60-65
2012
Clostridium acetobutylicum, Escherichia coli, Streptomyces avermitilis, Streptomyces coelicolor, Streptomyces avermitilis MA-4680, Escherichia coli ML103
Manually annotated by BRENDA team
Hong, S.K.; Kim, K.H.; Park, J.K.; Jeong, K.W.; Kim, Y.; Kim, E.E.
New design platform for malonyl-CoA-acyl carrier protein transacylase
FEBS Lett.
584
1240-1244
2010
Streptococcus pneumoniae, Staphylococcus aureus (Q99UN8), Staphylococcus aureus
Manually annotated by BRENDA team
Sun, M.; Zhu, G.; Qin, Z.; Wu, C.; Lv, M.; Liao, S.; Qi, N.; Xie, M.; Cai, J.
Functional characterizations of malonyl-CoA:acyl carrier protein transacylase (MCAT) in Eimeria tenella
Mol. Biochem. Parasitol.
184
20-28
2012
Eimeria tenella
Manually annotated by BRENDA team
Natarajan, S.; Kim, J.K.; Jung, T.K.; Doan, T.T.; Ngo, H.P.; Hong, M.K.; Kim, S.; Tan, V.P.; Ahn, S.J.; Lee, S.H.; Han, Y.; Ahn, Y.J.; Kang, L.W.
Crystal structure of malonyl CoA-Acyl carrier protein transacylase from Xanthomanous oryzae pv. oryzae and its proposed binding with ACP
Mol. Cells
33
19-25
2012
Xanthomonas oryzae
Manually annotated by BRENDA team
Liu, Y.; Zhang, Y.; Cao, X.; Xue, S.
Cloning, purification, crystallization and preliminary X-ray crystallographic analysis of MCAT from Synechocystis sp. PCC 6803
Acta Crystallogr. Sect. F
69
1256-1259
2013
Synechocystis sp. (P73242), Synechocystis sp.
Manually annotated by BRENDA team
Liu, Y.; Feng, Y.; Wang, Y.; Li, X.; Cao, X.; Xue, S.
Structural and biochemical characterization of MCAT from photosynthetic microorganism Synechocystis sp. PCC 6803 reveal its stepwise catalytic mechanism
Biochem. Biophys. Res. Commun.
457
398-403
2015
Synechocystis sp. (P73242), Synechocystis sp.
Manually annotated by BRENDA team
Tian, J.; Zheng, M.; Yang, G.; Zheng, L.; Chen, J.; Yang, B.
Cloning and stress-responding expression analysis of malonyl CoA-acyl carrier protein transacylase gene of Nannochloropsis gaditana
Gene
530
33-38
2013
Nannochloropsis gaditana (S5VRZ9), Nannochloropsis gaditana
Manually annotated by BRENDA team
Cheng, R.; Ge, Y.; Yang, B.; Zhong, X.; Lin, X.; Huang, Z.
Cloning and functional analysis of putative malonyl-CoA:acyl-carrier protein transacylase gene from the docosahexaenoic acid-producer Schizochytrium sp. TIO1101
World J. Microbiol. Biotechnol.
29
959-967
2013
Schizochytrium sp. (S4TYX4), Schizochytrium sp., Schizochytrium sp. TIO1101 (S4TYX4)
Manually annotated by BRENDA team
Paiva, P.; Sousa, S.; Ramos, M.; Fernandes, P.
Understanding the catalytic machinery and the reaction pathway of the malonyl-acetyl transferase domain of human fatty acid synthase
ACS Catal.
8
4860-4872
2018
Homo sapiens (P49327)
-
Manually annotated by BRENDA team
Marcella, A.M.; Barb, A.W.
The R117A variant of the Escherichia coli transacylase FabD synthesizes novel acyl-(acyl carrier proteins)
Appl. Microbiol. Biotechnol.
101
8431-8441
2017
Escherichia coli
Manually annotated by BRENDA team
Marcella, A.M.; Barb, A.W.
Acyl-coenzyme A (holo-acyl carrier protein) transacylase enzymes as templates for engineering
Appl. Microbiol. Biotechnol.
102
6333-6341
2018
Escherichia coli (P0AAI9)
Manually annotated by BRENDA team
Lee, W.; Park, J.; Balasubramanian, P.; Kim, Y.
Elucidation of the crystal structure of FabD from the multidrug-resistant bacterium Acinetobacter baumannii
Biochem. Biophys. Res. Commun.
505
208-214
2018
Acinetobacter baumannii (V5VFX0)
Manually annotated by BRENDA team
Kumar, V.; Sharma, A.; Pratap, S.; Kumar, P.
Biophysical and in silico interaction studies of aporphine alkaloids with malonyl-CoA ACP transacylase (FabD) from drug resistant Moraxella catarrhalis
Biochimie
149
18-33
2018
Moraxella catarrhalis
Manually annotated by BRENDA team
Chen, J.W.; Liu, W.J.; Hu, D.X.; Wang, X.; Balamurugan, S.; Alimujiang, A.; Yang, W.D.; Liu, J.S.; Li, H.Y.
Identification of a malonyl CoA-acyl carrier protein transacylase and its regulatory role in fatty acid biosynthesis in oleaginous microalga Nannochloropsis oceanica
Biotechnol. Appl. Biochem.
64
620-626
2017
Nannochloropsis oceanica
Manually annotated by BRENDA team
Paiva, P.; Sousa, S.; Fernandes, P.; Joao Ramos, M.
Human Fatty Acid Synthase A Computational study of the transfer of the acyl moieties from mat to the ACP domain
ChemCatChem
11
3853-3864
2019
Homo sapiens
-
Manually annotated by BRENDA team
Li, H.; Yuan, S.; Minegishi, Y.; Suga, A.; Yoshitake, K.; Sheng, X.; Ye, J.; Smith, S.; Bunkoczi, G.; Yamamoto, M.; Iwata, T.
Novel mutations in malonyl-CoA-acyl carrier protein transacylase provoke autosomal recessive optic neuropathy
Hum. Mol. Genet.
29
444-458
2020
Homo sapiens
Manually annotated by BRENDA team
Li, Z.; Meng, T.; Ling, X.; Li, J.; Zheng, C.; Shi, Y.; Chen, Z.; Li, Z.; Li, Q.; Lu, Y.; He, N.
Overexpression of malonyl-CoA ACP transacylase in Schizochytrium sp. to improve polyunsaturated fatty acid production
J. Agric. Food Chem.
66
5382-5391
2018
Schizochytrium sp. MYA1381 (A0A345ANG7)
Manually annotated by BRENDA team
Zhang, Y.; Ye, J.; Fan, J.
Regulation of malonyl-CoA-acyl carrier protein transacylase network in umbilical cord blood affected by intrauterine hyperglycemia
Oncotarget
8
75254-75263
2017
Homo sapiens (Q8IVS2), Homo sapiens
Manually annotated by BRENDA team
Jung, S.H.; Kim, R.J.; Kim, K.J.; Lee, D.H.; Suh, M.C.
Plastidial and mitochondrial malonyl CoA-ACP malonyltransferase is essential for cell division and its overexpression increases storage oil content
Plant Cell Physiol.
60
1239-1249
2019
Arabidopsis thaliana
Manually annotated by BRENDA team