Reference on EC 2.3.1.31 - homoserine O-acetyltransferase
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Yamagata, S.
Acetyl-CoA: L-homoserine O-acetyltransferase of the yeast Saccharomyces: substrate kinetics
Kyoyobu Kenkyu Hokoku
24
27-28
1988
Paenibacillus polymyxa, [Brevibacterium] flavum, Saccharomyces cerevisiae
-
Nagai, S.; Kerr, D.
Homoserine transacetylase (Neurospora)
Methods Enzymol.
17B
442-445
1971
Neurospora sp.
-
Miyajima, R.; Shiio, I.
Regulation of aspartate family amino acid biosynthesis in Brevibacterium flavum. VII. Properities of homoserine O-transacetylase
J. Biochem.
73
1061-1068
1973
[Brevibacterium] flavum
Wyman, A.; Paulus, H.
Purification and properties of homoserine transacetylase from Bacillus polymyxa
J. Biol. Chem.
250
3897-3903
1975
Paenibacillus polymyxa
Langin, T.; Faugeron, G.; Goyon, C.; Nicolas, A.; Rossignol, J.L.
The MET2 gene of Saccharomyces cerevisiae: molecular cloning and nucleotide sequence
Gene
49
283-293
1986
Saccharomyces cerevisiae
Yamagata, S.
Partial purification and some properties of homoserine O-acetyltransferase of a methionine auxotroph of Saccharomyces cerevisiae
J. Bacteriol.
169
3458-3463
1987
Saccharomyces cerevisiae
Goyon, C.; Faugeron, G.; Rossignol, J.L.
Molecular cloning and characterization of the met2 gene from Ascobolus immersus
Gene
63
297-308
1988
Ascobolus immersus
Nagai, S.; Flavin, M.
Acetylhomoserine. An intermediate in the fungal biosynthesis of methionine
J. Biol. Chem.
242
3884-3895
1967
Neurospora sp.
Bourhy, P.; Martel, A.; Margarita, D.; Saint Girons, I.; Belfaiza, J.
Homoserine O-acetyltransferase, involved in the Leptospira meyeri methionine biosynthetic pathway, is not feedback inhibited
J. Bacteriol.
179
4396-4398
1997
Leptospira meyeri (P94891), Leptospira meyeri
Born, T.L.; Franklin, M.; Blanchard, J.S.
Enzyme-catalyzed acylation of homoserine: mechanistic characterization of the Haemophilus influenzae met2-encoded homoserine transacetylase
Biochemistry
39
8556-8564
2000
Haemophilus influenzae
Park, S.D.; Lee, J.Y.; Kim, Y.; Kim, J.H.; Lee, H.S.
Isolation and analysis of metA, a methionine biosynthetic gene encoding homoserine acetyltransferase in Corynebacterium glutamicum
Mol. Cell
8
286-294
1998
Corynebacterium glutamicum
Han, Y.K.; Lee, T.; Han, K.H.; Yun, S.H.; Lee, Y.W.
Functional analysis of the homoserine O-acetyltransferase gene and its identification as a selectable marker in Gibberella zeae
Curr. Genet.
46
205-212
2004
Fusarium graminearum
Nazi, I.; Wright, G.D.
Catalytic mechanism of fungal homoserine transacetylase
Biochemistry
44
13560-13566
2005
Schizosaccharomyces pombe
Mirza, I.A.; Nazi, I.; Korczynska, M.; Wright, G.D.; Berghuis, A.M.
Crystal structure of homoserine transacetylase from Haemophilus influenzae reveals a new family of alpha/beta-hydrolases
Biochemistry
44
15768-15773
2005
Haemophilus influenzae (P45131), Haemophilus influenzae
Goudarzi, M.; Born, T.L.
Purification and characterization of Thermotoga maritima homoserine transsuccinylase indicates it is a transacetylase
Extremophiles
10
469-478
2006
Thermotoga maritima
Nazi, I.; Scott, A.; Sham, A.; Rossi, L.; Williamson, P.R.; Kronstad, J.W.; Wright, G.D.
Role of homoserine transacetylase as a new target for antifungal agents
Antimicrob. Agents Chemother.
51
1731-1736
2007
Cryptococcus neoformans
Wang, M.; Liu, L.; Wang, Y.; Wei, Z.; Zhang, P.; Li, Y.; Jiang, X.; Xu, H.; Gong, W.
Crystal structure of homoserine O-acetyltransferase from Leptospira interrogans
Biochem. Biophys. Res. Commun.
363
1050-1056
2007
Leptospira interrogans (Q8F4I0), Leptospira interrogans
Zubieta, C.; Arkus, K.A.; Cahoon, R.E.; Jez, J.M.
A single amino acid change is responsible for evolution of acyltransferase specificity in bacterial methionine biosynthesis
J. Biol. Chem.
283
7561-7567
2008
Bacillus cereus
De Pascale, G.; Nazi, I.; Harrison, P.H.; Wright, G.D.
beta-Lactone natural products and derivatives inactivate homoserine transacetylase, a target for antimicrobial agents
J. Antibiot.
64
483-487
2011
Haemophilus influenzae
Thangavelu, B.; Pavlovsky, A.G.; Viola, R.
Structure of homoserine O-acetyltransferase from Staphylococcus aureus: the first Gram-positive ortholog structure
Acta Crystallogr. Sect. F
70
1340-1345
2014
Staphylococcus aureus
Oda, K.; Matoba, Y.; Kumagai, T.; Noda, M.; Sugiyama, M.
Crystallographic study to determine the substrate specificity of an L-serine-acetylating enzyme found in the D-cycloserine biosynthetic pathway
J. Bacteriol.
195
1741-1749
2013
Streptomyces lavendulae (D2Z028), Streptomyces lavendulae ATCC 11924 (D2Z028)
Sagong, H.Y.; Hong, J.; Kim, K.J.
Crystal structure and biochemical characterization of O-acetylhomoserine acetyltransferase from Mycobacterium smegmatisATCC 19420
Biochem. Biophys. Res. Commun.
517
399-406
2019
Mycolicibacterium smegmatis (A0A8B4QGM8), Mycolicibacterium smegmatis, Mycolicibacterium smegmatis ATCC 19420 (A0A8B4QGM8)
Toelzer, C.; Pal, S.; Watzlawick, H.; Altenbuchner, J.; Niefind, K.
A novel esterase subfamily with alpha/beta-hydrolase fold suggested by structures of two bacterial enzymes homologous to L-homoserine O-acetyl transferases
FEBS Lett.
590
174-184
2016
no activity in Corynebacterium glutamicum, no activity in Pseudomonas veronii
Chaton, C.T.; Rodriguez, E.S.; Reed, R.W.; Li, J.; Kenner, C.W.; Korotkov, K.V.
Structural analysis of mycobacterial homoserine transacetylases central to methionine biosynthesis reveals druggable active site
Sci. Rep.
9
20267
2019
Mycobacteroides abscessus (B1MG17), Mycolicibacterium hassiacum (K5B926), Mycolicibacterium hassiacum, Mycobacterium tuberculosis (P9WJY9), Mycobacterium tuberculosis, Mycobacteroides abscessus JCM 13569 (B1MG17), Mycolicibacterium hassiacum DSM 44199 (K5B926), Mycolicibacterium hassiacum JCM 12690 (K5B926), Mycolicibacterium hassiacum CIP 105218 (K5B926), Mycobacteroides abscessus CIP 104536 (B1MG17), Mycobacteroides abscessus DSM 44196 (B1MG17), Mycobacteroides abscessus ATCC 19977 (B1MG17), Mycolicibacterium hassiacum 3849 (K5B926), Mycobacteroides abscessus NCTC 13031 (B1MG17), Mycobacteroides abscessus TMC 1543 (B1MG17)
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