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Information on EC 2.3.1.247 - 3-keto-5-aminohexanoate cleavage enzyme

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IUBMB Comments
Requires Zn2+. The enzyme, isolated from the bacteria Fusobacterium nucleatum and Cloacimonas acidaminovorans, is involved in the anaerobic fermentation of lysine.
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The enzyme appears in viruses and cellular organisms
Synonyms
3-keto,5-aminohexanoate cleavage enzyme, FN1868, kce, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(5S)-5-amino-3-oxohexanoate + acetyl-CoA = L-3-aminobutanoyl-CoA + acetoacetate
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