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Information on EC 2.3.1.237 - neocarzinostatin naphthoate synthase

for references in articles please use BRENDA:EC2.3.1.237
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IUBMB Comments
A multi-domain polyketide synthase involved in the synthesis of neocarzinostatin in the bacterium Streptomyces carzinostaticus.
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The expected taxonomic range for this enzyme is: Streptomyces carzinostaticus
Synonyms
naphthoic acid synthase, ncsB, NNS, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
acetyl-CoA + 5 malonyl-CoA + 2 NADPH + 2 H+ = 2-hydroxy-5-methyl-1-naphthoate + 6 CoA + 5 CO2 + 3 H2O + 2 NADP+
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