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Information on EC 2.3.1.217 - curcumin synthase

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EC Tree
     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.217 curcumin synthase
IUBMB Comments
A polyketide synthase from the plant Curcuma longa (turmeric). Three isoforms exist, CURS1, CURS2 and CURS3. While CURS1 and CURS2 prefer feruloyl-CoA as a starter substrate, CURS3 can accept 4-coumaroyl-CoA equally well (see EC 2.3.1.219, demethoxycurcumin synthase).
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
curcumin synthase, curcumin synthase 1, CURS, CURS1, CURS2, CURS3, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
feruloyl-CoA + feruloylacetyl-CoA + H2O = 2 CoA + curcumin + CO2
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