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Information on EC 2.3.1.169 - CO-methylating acetyl-CoA synthase

for references in articles please use BRENDA:EC2.3.1.169
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IUBMB Comments
Contains nickel, copper and iron-sulfur clusters. Involved, together with EC 1.2.7.4, carbon-monoxide dehydrogenase (ferredoxin), in the synthesis of acetyl-CoA from CO2 and H2.
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The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Reaction Schemes
+
a [Co(I) corrinoid Fe-S protein]
=
+
+
a [methyl-Co(III) corrinoid Fe-S protein]
Synonyms
acsch, co dehydrogenase enzyme complex, carbon monoxide dehydrogenase/acetyl-coenzyme a synthase, carbon monoxide dehydrogenase/acetyl coenzyme a synthase, co dehydrogenase/acetyl coa synthase, multienzyme carbon monoxide dehydrogenase complex, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
acetyl-CoA + a [Co(I) corrinoid Fe-S protein] = CO + CoA + a [methyl-Co(III) corrinoid Fe-S protein]
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