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Information on EC 2.3.1.166 - 2alpha-hydroxytaxane 2-O-benzoyltransferase

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IUBMB Comments
The enzyme was studied using the semisynthetic substrate 2-debenzoyl-7,13-diacetylbaccatin III. It will not acylate the hydroxy group at 1beta, 7beta, 10beta or 13alpha of 10-deacetyl baccatin III, or at 2alpha or 5alpha of taxa-4(20),11-diene-2alpha,5alpha-diol.
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The enzyme appears in viruses and cellular organisms
Synonyms
2-O-benzoyltransferase, benzoyl-CoA:taxane 2alpha-O-benzoyltransferase, benzoyltransferase, taxane 2alpha-O-, mTBT, taxane 2alpha-O-benzoyltransferase, TBT, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
benzoyl-CoA + 10-deacetyl-2-debenzoylbaccatin III = CoA + 10-deacetylbaccatin III
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