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Information on EC 2.3.1.165 - 6-methylsalicylic-acid synthase

for references in articles please use BRENDA:EC2.3.1.165
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IUBMB Comments
A multienzyme complex with a 4'-phosphopantetheine prosthetic group on the acyl carrier protein. It has a similar sequence to vertebrate type I fatty acid synthase. Acetoacetyl-CoA can also act as a starter molecule.
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Word Map
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
msas, 6-methylsalicylic acid synthase, iterative type i polyketide synthase, 6-msa, 6-msas, 6-methylsalicylic acid synthetase, aomsas, 6-msa synthase, methylsalicylic acid synthase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
acetyl-CoA + 3 malonyl-CoA + NADPH + H+ = 6-methylsalicylate + 4 CoA + 3 CO2 + NADP+ + H2O
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