Reference on EC 2.3.1.161 - lovastatin nonaketide synthase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Auclair, K.; Sutherland, A.; Kennedy, J.; Witter, D.J.; Van den Heever, J.P.; Hutchinson, C.R.; Vederas, J.C.
Lovastatin nonaketide synthase catalyzes an intramolecular Diels-Alder reaction of a substrate analogue
J. Am. Chem. Soc.
122
11519-11520
2000
Aspergillus terreus
-
Manually annotated by BRENDA team
Hendrickson, L.; Davis, C.R.; Roach, C.; Nguyen, D.K.; Aldrich, T.; McAda, P.C.; Reeves, C.D.
Lovastatin biosynthesis in Aspergillus terreus: characterization of blocked mutants, enzyme activities and a multifunctional polyketide synthase gene
Chem. Biol.
6
429-439
1999
Aspergillus terreus
Manually annotated by BRENDA team
Hutchinson, C.R.; Kennedy, J.; Park, C.; Kendrew, S.; Auclair, K.; Vederas, J.
Aspects of the biosynthesis of non-aromatic fungal polyketides by iterative polyketide synthases
Antonie van Leeuwenhoek
78
287-295
2000
Aspergillus terreus
Manually annotated by BRENDA team
Kennedy, J.; Auclair, K.; Kendrew, S.G.; Park, C.; Vederas, J.C.; Hutchinson, C.R.
Modulation of polyketide synthase activity by accessory proteins during lovastatin biosynthesis
Science
284
1368-1372
1999
Aspergillus terreus
Manually annotated by BRENDA team
Sorensen, J.L.; Auclair, K.; Kennedy, J.; Hutchinson, C.R.; Vederas, J.C.
Transformations of cyclic nonaketides by Aspergillus terreus mutants blocked for lovastatin biosynthesis at the lovA and lovC genes
Org. Biomol. Chem.
1
50-59
2003
Aspergillus terreus
Manually annotated by BRENDA team
Ma, S.M.; Tang, Y.
Biochemical characterization of the minimal polyketide synthase domains in the lovastatin nonaketide synthase LovB
FEBS J.
274
2854-2864
2007
Aspergillus terreus, Aspergillus terreus (Q9Y8A5)
Manually annotated by BRENDA team
Burr, D.A.; Chen, X.B.; Vederas, J.C.
Syntheses of conjugated pyrones for the enzymatic assay of lovastatin nonaketide synthase, an iterative polyketide synthase
Org. Lett.
9
161-164
2007
Aspergillus terreus, Aspergillus terreus (Q9Y8A5)
Manually annotated by BRENDA team
Lee, K.K.; Da Silva, N.A.; Kealey, J.T.
Determination of the extent of phosphopantetheinylation of polyketide synthases expressed in Escherichia coli and Saccharomyces cerevisiae
Anal. Biochem.
394
75-80
2009
Aspergillus terreus
Manually annotated by BRENDA team
Ma, S.M.; Li, J.W.; Choi, J.W.; Zhou, H.; Lee, K.K.; Moorthie, V.A.; Xie, X.; Kealey, J.T.; Da Silva, N.A.; Vederas, J.C.; Tang, Y.
Complete reconstitution of a highly reducing iterative polyketide synthase
Science
326
589-592
2009
Aspergillus terreus
Manually annotated by BRENDA team
Xu, W.; Chooi, Y.; Choi, J.; Li, S.; Vederas, J.; Da Silva, N.; Tang, Y.
LovG: The thioesterase required for dihydromonacolin L release and lovastatin nonaketide synthase turnover in lovastatin biosynthesis
Angew. Chem. Int. Ed. Engl.
52
6472-6475
2013
Aspergillus terreus (Q9Y8A5)
Manually annotated by BRENDA team
Cacho, R.A.; Thuss, J.; Xu, W.; Sanichar, R.; Gao, Z.; Nguyen, A.; Vederas, J.C.; Tang, Y.
Understanding programming of fungal iterative polyketide synthases: the biochemical basis for regioselectivity by the methyltransferase domain in the lovastatin megasynthase
J. Am. Chem. Soc.
137
15688-15691
2015
Aspergillus terreus (Q9Y8A5)
Manually annotated by BRENDA team