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Information on EC - phospholipid:diacylglycerol acyltransferase

for references in articles please use BRENDA:EC2.3.1.158
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IUBMB Comments
This enzyme differs from EC, diacylglycerol O-acyltransferase, by synthesising triacylglycerol using an acyl-CoA-independent mechanism. The specificity of the enzyme for the acyl group in the phospholipid varies with species, e.g., the enzyme from castor bean (Ricinus communis) preferentially incorporates vernoloyl (12,13-epoxyoctadec-9-enoyl) groups into triacylglycerol, whereas that from the hawk's beard (Crepis palaestina) incorporates both ricinoleoyl (12-hydroxyoctadec-9-enoyl) and vernoloyl groups. The enzyme from the yeast Saccharomyces cerevisiae specifically transfers acyl groups from the sn-2 position of the phospholipid to diacylglycerol, thus forming an sn-1-lysophospholipid.
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The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
acyl-CoA-independent phospholipid:diacylglycerol acyltransferase, CHLREDRAFT_184281, CHLREDRAFT_188937, DGTT1, DGTT2, DGTT3, diacylglycerol acyltransferase type 2, PDAT, PDAT1, PDAT1A, more
phospholipid + 1,2-diacyl-sn-glycerol = lysophospholipid + triacylglycerol
show the reaction diagram
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