Reference on EC 2.3.1.12 - dihydrolipoyllysine-residue acetyltransferase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Reed, L.J.; Yeaman, S.J.
Pyruvate dehydrogenase
The Enzymes, 3rd Ed. (Boyer, P. D. , ed. )
18
77-95
1987
Geobacillus stearothermophilus, Mammalia
-
Linn, T.C.; Pelley, J.W.; Pettit, F.H.; Hucho, F.; Randall, D.D.; Reed, L.J.
alpha-Keto acid dehydrogenase complexes. XV. Purification and properties of the component enzymes of the pyruvate dehydrogenase complexes from bovine kidney and heart
Arch. Biochem. Biophys.
148
327-342
1972
Bos taurus
Yeaman, S.J.
The mammalian 2-oxoacid dehydrogenases: a complex family
Trends Biochem. Sci.
11
293-296
1986
Bos taurus, Mammalia, Sus scrofa
-
Phelps, A.; Lindsay, J.G.
Mammalian pyruvate dehydrogenase complex binds tightly to the mitochondrial inner membrane
Biochem. Soc. Trans.
14
893
1986
Bos taurus
-
De Kok, A.; Westphal, A.H.
Hybrid pyruvate dehydrogenase complexes reconstituted from components of the complexes from Escherichia coli and Azotobacter vinelandii
Eur. J. Biochem.
152
35-41
1985
Azotobacter vinelandii, Escherichia coli
Wu, T.L.; Reed, L.J.
Subunit binding in the pyruvate dehydrogenase complex from bovine kidney and heart
Biochemistry
23
221-226
1984
Bos taurus
Matuda, S.; Shirahama, T.; Saheki, T.; Miura, S.; Mori, M.
Purification and immunochemical studies of pyruvate dehydrogenase complex from rat heart, and cell-free synthesis of lipoamide dehydrogenase, a component of the complex
Biochim. Biophys. Acta
741
86-93
1983
Rattus norvegicus
Graupe, K.; Abusaud, M.; Karfunkel, H.; Bisswanger, H.
Reassociation of the pyruvate dehydrogenase complex from Escherichia coli: Kinetic measurements and binding studies by resonance energy transfer
Biochemistry
21
1386-1394
1982
Escherichia coli
Seckler, R.; Binder, R.; Bisswanger, H.
Purification and properties of the pyruvate dehydrogenase complex from Salmonella typhimurium and formation of hybrids with the enzyme complex from Escherichia coli
Biochim. Biophys. Acta
705
210-217
1982
Salmonella enterica subsp. enterica serovar Typhimurium
Harada, T.; Hirabayashi, T.
Pyruvate dehydrogenase complex from Hansenula
Methods Enzymol.
89
420-423
1982
Hansenula miso
Furuta, S.; Hashimoto, T.
Pyruvate dehydrogenase complex from pigeon breast muscle
Methods Enzymol.
89
414-420
1982
Columba sp.
Randall, D.D.
Pyruvate dehydrogenase complex from broccoli and cauliflower
Methods Enzymol.
89
408-414
1982
Brassica oleracea, Brassica oleracea var. botrytis
-
Harding, R.W.; Caroline, D.F.; Wagner, R.P.
Pyruvate dehydrogenase complex from Neurospora
Methods Enzymol.
89
386-391
1982
Neurospora crassa
Pettit, F.H.; Reed, L.J.
Pyruvate dehydrogenase complex from bovine kidney and heart
Methods Enzymol.
89
376-386
1982
Bos taurus
Kresze, G.B.; Ronft, H.
Pyruvate dehydrogenase complex from bakers yeast. 2. Molecular structure, dissociation, and implications for the origin of mitochondria
Eur. J. Biochem.
119
581-587
1981
Saccharomyces cerevisiae
Guest, J.R.; Stephens, P.E.
Molecular cloning of the pyruvate dehydrogenase complex genes of Escherichia coli
J. Gen. Microbiol.
121
277-292
1980
Escherichia coli
Visser, J.; Kester, H.; Huigen, A.
Purification and some properties of the pyruvate dehydrogenase complex of Bacillus subtilis
FEMS Microbiol. Lett.
9
227-232
1980
Bacillus subtilis
-
Henderson, C.E.; Perham, R.N.
Purificaton of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus and resolution of its four component polypeptides
Biochem. J.
189
161-172
1980
Geobacillus stearothermophilus
Danson, M.J.; Hale, G.; Johnson, P.; Perham, R.N.
Molecular weight and symmetry of the pyruvate dehydrogenase multienzyme complex of Escherichia coli
J. Mol. Biol.
129
603-617
1979
Escherichia coli
Guest, J.R.; Darlison, M.G.; Spencer, M.E.; Stephens, P.E.
Cloning and sequence analysis of the pyruvate and 2-oxoglutarate dehydrogenase complex genes of Escherichia coli
Biochem. Soc. Trans.
12
220-223
1984
Escherichia coli
Borges, A.; Hawkins, C.F.; Packman, L.C.; Perham, R.N.
Cloning and sequence analysis of the genes encoding the dihydrolipoamide acetyltransferase and dihydrolipoamide dehydrogenase components of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus
Eur. J. Biochem.
194
95-102
1990
Geobacillus stearothermophilus
Ali, S.T.; Guest, J.R.
Isolation and characterization of lipoylated and unlipoylated domains of the E2p subunit of the pyruvate dehydrogenase complex of Escherichia coli
Biochem. J.
271
139-145
1990
Escherichia coli
Dardel, F.; Packman, L.C.; Perham, R.N.
Expression in Escherichia coli of a sub-gene encoding the lipoyl domain of the pyruvate dehydrogenase complex of Bacillus stearothermophilus [published erratum appears in FEBS Lett 1990 Jul 30;268(1):306]
FEBS Lett.
264
206-210
1990
Geobacillus stearothermophilus
Oppermann, F.B.; Schmidt, B.; Steinbuchel, A.
Purification and characterization of acetoin:2,6-dichlorophenolindophenol oxidoreductase, dihydrolipoamide dehydrogenase, and dihydrolipoamide acetyltransferase of the Pelobacter carbinolicus acetoin dehydrogenase enzyme system
J. Bacteriol.
173
757-767
1991
Syntrophotalea carbinolica
Niu, X.D.; Browning, K.S.; Behal, R.H.; Reed, L.J.
Cloning and nucleotide sequence of the gene for dihydrolipoamide acetyltransferase from Saccharomyces cerevisiae
Proc. Natl. Acad. Sci. USA
85
7546-7550
1988
Saccharomyces cerevisiae
Hanemaaijer, R.; Westphal, A.H.; Berg, A.; van Dongen, W.; de Kok, A.; Veeger, C.
The gene encoding dihydrolipoyl transacetylase from Azotobacter vinelandii. Expression in Escherichia coli and activation and isolation of the protein
Eur. J. Biochem.
181
47-53
1989
Azotobacter vinelandii
Hanemaaijer, R.; Janssen, A.; de Kok, A.; Veeger, C.
The dihydrolipoyltransacetylase component of the pyruvate dehydrogenase complex from Azotobacter vinelandii. Molecular cloning and sequence analysis
Eur. J. Biochem.
174
593-599
1988
Azotobacter vinelandii
Hanemaaijer, R.; Westphal, A.H.; van der Heiden, T.; de Kok, A.; Veeger, C.
The quaternary structure of the dihydrolipoyl transacetylase component of the pyruvate dehydrogenase complex from Azotobacter vinelandii. A reconsideration
Eur. J. Biochem.
179
287-292
1989
Azotobacter vinelandii
Hanemaaijer, R.; de Kok, A.; Jolles, J.; Veeger, C.
The domain structure of the dihydrolipoyl transacetylase component of the pyruvate dehydrogenase complex from Azotobacter vinelandii
Eur. J. Biochem.
169
245-252
1987
Azotobacter vinelandii
Powers-Greenwood, S.L.; Rahmatullah, M.; Radke, G.A.; Roche, T.E.
Separation of protein X from the dihydrolipoyl transacetylase component of the mammalian pyruvate dehydrogenase complex and function of protein X
J. Biol. Chem.
264
3655-3657
1989
Bos taurus
Rahmatullah, M.; Gopalakrishnan, S.; Andrews, P.C.; Chang, C.L.; Radke, G.A.; Roche, T.E.
Subunit associations in the mammalian pyruvate dehydrogenase complex. Structure and role of protein X and the pyruvate dehydrogenase component binding domain of the dihydrolipoyl transacetylase component
J. Biol. Chem.
264
2221-2227
1989
Bos taurus
Rahmatullah, M.; Gopalakrishnan, S.; Radke, G.A.; Roche, T.E.
Domain structures of the dihydrolipoyl transacetylase and the protein X components of mammalian pyruvate dehydrogenase complex. Selective cleavage by protease Arg C
J. Biol. Chem.
264
1245-1251
1989
Bos taurus
Hanemaaijer, R.; Masurel, R.; Visser, A.J.W.G.; de Kok, A.; Veeger, C.
Time-resolved fluorescence studies on the dihydrolipoyl transacetylase (E2) component of the pyruvate dehydrogenase complex from Azotobacter vinelandii
FEBS Lett.
238
285-288
1988
Azotobacter vinelandii
Packman, L.C.; Borges, A.; Perham, R.N.
Amino acid sequence analysis of the lipoyl and peripheral subunit-binding domains in the lipoate acetyltransferase component of the pyruvate dehydrogenase complex from Bacillus stearothermophilus
Biochem. J.
252
79-86
1988
Geobacillus stearothermophilus
Thekkumkara, T.J.; Jesse, B.W.; Ho, L.; Raefsky, C.; Pepin, R.A.; Javed, A.A.; Pons, G.; Patel, M.S.
Isolation of a cDNA clone for the dihydrolipoamide acetyltransferase component of the human liver pyruvate dehydrogenase complex
Biochem. Biophys. Res. Commun.
145
903-907
1987
Homo sapiens
Matuda, S.; Matuo, S.; Nakano, K.; Saheki, T.
Molecular cloning of cDNA for rat liver lipoate acetyltransferase. A component of pyruvate dehydrogenase complex
Biochem. Biophys. Res. Commun.
142
953-957
1987
Rattus norvegicus
Guest, J.R.; Lewis, H.M.; Graham, L.D.; Packman, L.C.; Perham, R.N.
Genetic reconstruction and functional analysis of the repeating lipoyl domains in the pyruvate dehydrogenase multienzyme complex of Escherichia coli
J. Mol. Biol.
185
743-754
1985
Escherichia coli
Lowe, P.N.; Hodgson, J.A.; Perham, R.N.
Limited proteolysis of the pyruvate dehydrogenase multienzyme complex of Bacillus subtilis
Biochem. J.
225
249-253
1985
Bacillus subtilis
Bosma, H.J.; de Kok, A.; van Markwijk, B.W.; Veeger, C.
The size of the pyruvate dehydrogenase complex of Azotobacter vinelandii. Association phenomena
Eur. J. Biochem.
140
273-280
1984
Azotobacter vinelandii
Packman, L.C.; Hale, G.; Perham, R.N.
Repeating functional domains in the pyruvate dehydrogenase multienzyme complex of Escherichia coli
EMBO J.
3
1315-1319
1984
Escherichia coli
Danson, M.J.; Porteous, C.E.
Pyruvate dehydrogenase multienzyme complex of Escherichia coli: determination of the Mr of the lipoate acetyltransferase component
FEBS Lett.
133
112-114
1981
Escherichia coli
Bleile, D.M.; Hackert, M.L.; Pettit, F.H.; Reed, L.J.
Subunit structure of dihydrolipoyl transacetylase component of pyruvate dehydrogenase complex from bovine heart
J. Biol. Chem.
256
514-519
1981
Bos taurus
Kresze, G.B.; Ronft, H.
Bovine kidney pyruvate dehydrogenase complex. Limited proteolysis and molecular structure of the lipoate acetyltransferase component
Eur. J. Biochem.
112
589-599
1980
Bos taurus
Machicao, F.; Wieland, O.H.
Subunit structure of dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex from bovine kidney
Hoppe-Seyler's Z. Physiol. Chem.
361
1093-1106
1980
Bos taurus
Kresze, G.B.; Dietl, B.; Ronft, H.
Mammalian lipoate acetyltransferase: molecular weight determination by gel filtration in the presence of guanidinium chloride
FEBS Lett.
112
48-50
1980
Bos taurus
Bleile, D.M.; Munk, P.; Oliver, R.M.; Reed, L.J.
Subunit structure of dihydrolipoyl transacetylase component of pyruvate dehydrogenase complex from Escherichia coli
Proc. Natl. Acad. Sci. USA
76
4385-4389
1979
Escherichia coli
Fuller, C.C.; Reed, L.J.; Oliver, R.M.; Hackert, M.L.
Crystallization of a dihydrolipoyl transacetylase - dihydrolipoyl dehydrogenase subcomplex and its implications regarding the subunit structure of the pyruvate dehydrogenase complex from Escherichia coli
Biochem. Biophys. Res. Commun.
90
431-438
1979
Escherichia coli
Reed, L.J.; Pettit, F.H.; Eley, M.H.; Hamilton, L.; Collins, J.H.; Oliver, R.M.
Reconstitution of the Escherichia coli pyruvate dehydrogenase complex
Proc. Natl. Acad. Sci. USA
72
3068-3072
1975
Escherichia coli
Hamada, M.; Otsuka, K.I.; Tanaka, N.; Ogasahara, K.; Koike, K.; Hiraoka, T.; Koike, M.
Purification properties and subunit composition of pig heart lipoate acetyltransferase
J. Biochem.
78
187-197
1975
Sus scrofa
Butterworth, P.J.; Tsai, S.; Eley, M.H.; Roche, T.E.; Reed, L.J.
A kinetic study of dihydrolipoyl transacetylase from bovine kidney
J. Biol. Chem.
250
1921-1925
1975
Bos taurus
Bisswanger, H.; Henning, U.
A new dihydrolipoamide transacetylase in Escherichia coli K12
Biochim. Biophys. Acta
321
143-148
1973
Escherichia coli
Vogel, O.; Beikirch, H.; Muller, H.; Henning, U.
The subunit structure of the Escherichia coli K-12 pyruvate dehydrogenase complex. The dihydrolipoamide transacetylase component
Eur. J. Biochem.
20
169-178
1971
Escherichia coli
Schwartz, E.R.; Reed, L.J.
alpha-Keto acid dehydrogenase complexes. XII. Effects of acetylation on the activity and structure of the dihydrolipoyl transacetylase of Escherichia coli
J. Biol. Chem.
244
6074-6079
1969
Escherichia coli
Schwartz, E.; Reed, L.J.
alpha-Keto acid dehydrogenase complexes. IX. Effects of iodination of the tyrosyl residues on the properties of the dihydrolipoyl transacetylase of Escherichia coli
J. Biol. Chem.
243
639-643
1968
Escherichia coli
Henney, H.R.; Willms, C.R.; Muramatsu, T.; Mukherjee, B.B.; Reed, L.J.
alpha-Keto acid dehydrogenase complexes. VII. Isolation and partial characterization of the polypeptide chains in the dihydrolipoyl transacetylase of Escherichia coli
J. Biol. Chem.
242
898-901
1967
Escherichia coli
Willms, C.R.; Oliver, R.M.; Henney, H.R.; Mukherjee, B.B.; Reed, L.J.
alpha-Keto acid dehydrogenase complexes. VI. Dissociation and reconstitution of the dihydrolipoyl transacetylase of Escherichia coli
J. Biol. Chem.
242
889-897
1967
Escherichia coli
Luderitz, R.; Klemme, J.H.
Isolation and characterization of a membrane-bound pyruvate dehydrogenase complex from the phototropic bacterium Rhodopseudomonas capsulata
Z. Naturforsch. C
32c
351-361
1977
Rhodospirillum rubrum
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De Graaf-Hess, A.C.; de Kok, A.
Binding and dissociation of the pyruvate dehydrogenase complex of Azotobacter vinelandii on thiol--Sepharose
FEBS Lett.
143
261-264
1982
Azotobacter vinelandii
Ala' Aldeen, D.A.A.; Westphal, A.H.; De Kok, A.; Weston, V.; Atta, M.S.; Baldwin, T.J.; Bartley, J.; Borriello, S.P.
Cloning, sequencing, characterization and implications for vaccine design of the novel dihydrolipoyl acetyltransferase of Neisseria meningitidis
J. Med. Microbiol.
45
419-432
1996
Neisseria meningitidis
Allen, M.D.; Perham, R.N.
The catalytic domain of dihydrolipoyl acetyltransferase from the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus. Expression, purification and reversible denaturation
FEBS Lett.
413
339-343
1997
Geobacillus stearothermophilus
Aso, Y.; Nakajima, A.; Meno, K.; Ishiguro, M.
Thermally induced changes of lipoate acetyltransferase inner core isolated from the Bacillus stearothermophilus pyruvate dehydrogenase complex
Biosci. Biotechnol. Biochem.
65
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2001
Geobacillus stearothermophilus
Guan, Y.; Rawsthorne, S.; Scofield, G.; Shaw, P.; Doonan, J.
Cloning and characterization of a dihydrolipoamide acetyltransferase (E2) subunit of the pyruvate dehydrogenase complex from Arabidopsis thaliana
J. Biol. Chem.
270
5412-5417
1995
Arabidopsis thaliana
Hendle, J.; Mattevi, A.; Westphal, A.H.; Spee, J.; de Kok, A.; Teplyakov, A.; Hol, W.G.
Crystallographic and enzymatic investigations on the role of Ser558, His610, and Asn614 in the catalytic mechanism of Azotobacter vinelandii dihydrolipoamide acetyltransferase (E2p)
Biochemistry
34
4287-4298
1995
Azotobacter vinelandii
Jackson, J.C.; Vinluan, C.C.; Dragland, C.J.; Sundararajan, V.; Yan, B.; Gounarides, J.S.; Nirmala, N.R.; Topiol, S.; Ramage, P.; Blume, J.E.; Aicher, T.D.; Bell, P.A.; Mann, W.R.
Heterologously expressed inner lipoyl domain of dihydrolipoyl acetyltransferase inhibits ATP-dependent inactivation of pyruvate dehydrogenase complex, Identification of important amino acid residues
Biochem. J.
334
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1998
Homo sapiens
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Mande, S.S.; Sarfaty, S.; Allen, M.D.; Perham, R.N.; Hol, W.G.J.
Protein-protein interactions in the pyruvate dehydrogenase multienzyme complex: dihydrolipoamide dehydrogenase complexed with the binding domain of dihydrolipoamide acetyltransferase
Structure
4
277-286
1996
Geobacillus stearothermophilus
McCartney, R.G.; Sanderson, S.J.; Lindsay, J.G.
Refolding and reconstitution studies on the transacetylase-protein X (E2/X) subcomplex of the mammalian pyruvate dehydrogenase complex: Evidence for specific binding of the dihydrolipoamide dehydrogenase component to sites on reassembled E2
Biochemistry
36
6819-6826
1997
Homo sapiens
Millar, A.H.; Leaver, C.J.; Hill, S.A.
Characterization of the dihydrolipoamide acetyltransferase of the mitochondrial pyruvate dehydrogenase complex from potato and comparisons with similar enzymes in diverse plant species
Eur. J. Biochem.
264
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1999
Solanum tuberosum
Mooney, B.P.; Miernyk, J.A.; Randall, D.D.
Cloning and characterization of the dihydrolipoamide S-acetyltransferase subunit of the plastid pyruvate dehydrogenase complex (E2) from Arabidopsis
Plant Physiol.
120
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1999
Arabidopsis thaliana
Roche, T.E.; Powers-Greenwood, S.L.; Shi, W.F.; Zhang, W.B.; Ren, S.Z.; Roche, E.D.; Cox, D.J.; Sorensen, C.M.
Sizing of bovine heart and kidney pyruvate dehydrogenase complex and dihydrolipoyl transacetylase core by quasielastic light scattering
Biochemistry
32
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1993
Bos taurus
Schulze, E.; Westphal, A.H.; Obmolova, G.; Mattevi, A.; Hol, W.G.; de Kok, A.
The catalytic domain of the dihydrolipoyl transacetylase component of the pyruvate dehydrogenase complex from Azotobacter vinelandii and Escherichia coli. Expression, purification, properties and preliminary X-ray analysis
Eur. J. Biochem.
201
561-568
1991
Azotobacter vinelandii, Escherichia coli
Schulze, E.; Westphal, A.H.; Veenhuis, M.; de Kok, A.
Purification and cellular localization of wild type and mutated dihydrolipoyltransacetylases from Azotobacter vinelandii and Escherichia coli expressed in E. coli
Biochim. Biophys. Acta
1120
87-96
1992
Azotobacter vinelandii, Escherichia coli
Thelen, J.J.; Muszynski, M.G.; David, N.R.; Luethy, M.H.; Elthon, T.E.; Miernyk, J.A.; Randall, D.D.
The dihydrolipoamide S-acetyltransferase subunit of the mitochondrial pyruvate dehydrogenase complex from maize contains a single lipoyl domain
J. Biol. Chem.
274
21769-21775
1999
Zea mays (Q9SWR9)
Wang, L.; Kaneko, S.; Kagaya, M.; Ohno, H.; Honda, M.; Kobayashi, K.
Molecular cloning, and characterization and expression of dihydrolipoamide acetyltransferase component of murine pyruvate dehydrogenase complex in bile duct cancer cells
J. Gastroenterol.
37
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2002
Mus musculus
Yang, D.; Song, J.; Wagenknecht, T.; Roche, T.E.
Assembly and full functionality of recombinantly expressed dihydrolipoyl acetyltransferase component of the human pyruvate dehydrogenase complex
J. Biol. Chem.
272
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1997
Homo sapiens
Roche, T.E.; Hiromasa, Y.; Turkan, A.; Gong, X.; Peng, T.; Yan, X.; Kasten, S.A.; Bao, H.; Dong, J.
Essential roles of lipoyl domains in the activated function and control of pyruvate dehydrogenase kinases and phosphatase isoform 1
Eur. J. Biochem.
270
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2003
Homo sapiens, Rattus norvegicus
Jung, H.I.; Cooper, A.; Perham, R.N.
Interactions of the peripheral subunit-binding domain of the dihydrolipoyl acetyltransferase component in the assembly of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus
Eur. J. Biochem.
270
4488-4496
2003
Geobacillus stearothermophilus
Matic, J.N.; Wilton, J.L.; Towers, R.J.; Scarman, A.L.; Minion, F.C.; Walker, M.J.; Djordjevic, S.P.
The pyruvate dehydrogenase complex of Mycoplasma hyopneumoniae contains a novel lipoyl domain arrangement
Gene
319
99-106
2003
Mycoplasma hyopneumoniae (Q93T73)
Hiromasa, Y.; Roche, T.E.
Facilitated interaction between the pyruvate dehydrogenase kinase isoform 2 and the dihydrolipoyl acetyltransferase
J. Biol. Chem.
278
33681-33693
2003
Homo sapiens
Roche, T.E.; Hiromasa, Y.; Turkan, A.; Gong, X.; Peng, T.; Yan, X.; Kasten, S.A.; Bao, H.; Dong, J.
Central organization of mammalian pyruvate dehydrogenase (PD) complex and lipoyl domain-mediated activated function and control of PD kinases and phosphatase 1
Oxid. Stress Dis.
11
363-386
2004
Homo sapiens, Rattus norvegicus
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Wei, W.; Li, H.; Nemeria, N.; Jordan, F.
Expression and purification of the dihydrolipoamide acetyltransferase and dihydrolipoamide dehydrogenase subunits of the Escherichia coli pyruvate dehydrogenase multienzyme complex: a mass spectrometric assay for reductive acetylation of dihydrolipoamide acetyltransferase
Protein Expr. Purif.
28
140-150
2003
Escherichia coli
Tuganova, A.; Klyuyeva, A.; Popov, K.M.
Recognition of the inner lipoyl-bearing domain of dihydrolipoyl transacetylase and of the blood glucose-lowering compound AZD7545 by pyruvate dehydrogenase kinase 2
Biochemistry
46
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2007
Homo sapiens
Allen, M.D.; Broadhurst, R.W.; Solomon, R.G.; Perham, R.N.
Interaction of the E2 and E3 components of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus. Use of a truncated protein domain in NMR spectroscopy
FEBS J.
272
259-268
2005
Geobacillus stearothermophilus (P11961), Geobacillus stearothermophilus
Hiromasa, Y.; Hu, L.; Roche, T.E.
Ligand-induced effects on pyruvate dehydrogenase kinase isoform 2
J. Biol. Chem.
281
12568-12579
2006
Homo sapiens
Smolle, M.; Prior, A.E.; Brown, A.E.; Cooper, A.; Byron, O.; Lindsay, J.G.
A new level of architectural complexity in the human pyruvate dehydrogenase complex
J. Biol. Chem.
281
19772-19780
2006
Homo sapiens (P10515)
Milne, J.L.; Wu, X.; Borgnia, M.J.; Lengyel, J.S.; Brooks, B.R.; Shi, D.; Perham, R.N.; Subramaniam, S.
Molecular structure of a 9-MDa icosahedral pyruvate dehydrogenase subcomplex containing the E2 and E3 enzymes using cryoelectron microscopy
J. Biol. Chem.
281
4364-4370
2006
Geobacillus stearothermophilus (P11961), Geobacillus stearothermophilus
Easlon, E.; Tsang, F.; Dilova, I.; Wang, C.; Lu, S.P.; Skinner, C.; Lin, S.J.
The dihydrolipoamide acetyltransferase is a novel metabolic longevity factor and is required for calorie restriction-mediated life span extension
J. Biol. Chem.
282
6161-6171
2007
Saccharomyces cerevisiae, Saccharomyces cerevisiae (A6ZS09)
Fries, M.; Stott, K.M.; Reynolds, S.; Perham, R.N.
Distinct modes of recognition of the lipoyl domain as substrate by the E1 and E3 components of the pyruvate dehydrogenase multienzyme complex
J. Mol. Biol.
366
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2006
Geobacillus stearothermophilus
Korotchkina, L.G.; Patel, M.S.
Binding of pyruvate dehydrogenase to the core of the human pyruvate dehydrogenase complex
FEBS Lett.
582
468-472
2008
Homo sapiens
Yu, X.; Hiromasa, Y.; Tsen, H.; Stoops, J.K.; Roche, T.E.; Zhou, Z.H.
Structures of the human pyruvate dehydrogenase complex cores: a highly conserved catalytic center with flexible N-terminal domains
Structure
16
104-114
2008
Homo sapiens (P10515), Homo sapiens
Hiromasa, Y.; Yan, X.; Roche, T.E.
Specific ion influences on self-association of pyruvate dehydrogenase kinase isoform 2 (PDHK2), binding of PDHK2 to the L2 lipoyl domain, and effects of the lipoyl group-binding site inhibitor, Nov3r
Biochemistry
47
2312-2324
2008
Homo sapiens
Green, T.; Grigorian, A.; Klyuyeva, A.; Tuganova, A.; Luo, M.; Popov, K.
Structural and functional insights into the molecular mechanisms responsible for the regulation of pyruvate dehydrogenase kinase 2
J. Biol. Chem.
283
15789-15798
2008
Homo sapiens
Brautigam, C.A.; Wynn, R.M.; Chuang, J.L.; Chuang, D.T.
Subunit and catalytic component stoichiometries of an in vitro reconstituted human pyruvate dehydrogenase complex
J. Biol. Chem.
284
13086-13098
2009
Homo sapiens
Casteel, J.; Miernyk, J.A.; Thelen, J.J.
Mapping the lipoylation site of Arabidopsis thaliana plastidial dihydrolipoamide S-acetyltransferase using mass spectrometry and site-directed mutagenesis
Plant Physiol. Biochem.
49
1355-1361
2011
Arabidopsis thaliana
Chandrasekhar, K.; Wang, J.; Arjunan, P.; Sax, M.; Park, Y.H.; Nemeria, N.S.; Kumaran, S.; Song, J.; Jordan, F.; Furey, W.
Insight to the interaction of the dihydrolipoamide acetyltransferase (E2) core with the peripheral components in the Escherichia coli pyruvate dehydrogenase complex via multifaceted structural approaches
J. Biol. Chem.
288
15402-15417
2013
Escherichia coli (P06959), Escherichia coli
Chen, R.; Xiao, M.; Gao, H.; Chen, Y.; Li, Y.; Liu, Y.; Zhang, N.
Identification of a novel mitochondrial interacting protein of C1QBP using subcellular fractionation coupled with CoIP-MS
Anal. Bioanal. Chem.
408
1557-1564
2016
Homo sapiens
Wang, J.; Nemeria, N.S.; Chandrasekhar, K.; Kumaran, S.; Arjunan, P.; Reynolds, S.; Calero, G.; Brukh, R.; Kakalis, L.; Furey, W.; Jordan, F.
Structure and function of the catalytic domain of the dihydrolipoyl acetyltransferase component in Escherichia coli pyruvate dehydrogenase complex
J. Biol. Chem.
289
15215-15230
2014
Escherichia coli (P06959), Escherichia coli
Arjunan, P.; Wang, J.; Nemeria, N.S.; Reynolds, S.; Brown, I.; Chandrasekhar, K.; Calero, G.; Jordan, F.; Furey, W.
Novel binding motif and new flexibility revealed by structural analyses of a pyruvate dehydrogenase-dihydrolipoyl acetyltransferase subcomplex from the Escherichia coli pyruvate dehydrogenase multienzyme complex
J. Biol. Chem.
289
30161-30176
2014
Escherichia coli (P06959)
Subashchandrabose, S.; Logeshwaran, P.; Venkateswarlu, K.; Naidu, R.; Megharaj, M.
Pyrene degradation by Chlorella sp. MM3 in liquid medium and soil slurry Possible role of dihydrolipoamide acetyltransferase in pyrene biodegradation
Algal Res.
23
223-232
2017
Chlorella sp. MM3
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