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Information on EC 2.2.1.6 - acetolactate synthase

for references in articles please use BRENDA:EC2.2.1.6
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EC Tree
IUBMB Comments
This enzyme requires thiamine diphosphate. The reaction shown is in the pathway of biosynthesis of valine; the enzyme can also transfer the acetaldehyde from pyruvate to 2-oxobutanoate, forming 2-ethyl-2-hydroxy-3-oxobutanoate, also known as 2-aceto-2-hydroxybutanoate, a reaction in the biosynthesis of isoleucine.
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Word Map
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria, Archaea
Reaction Schemes
Synonyms
acetohydroxyacid synthase, acetohydroxy acid synthase, alpha-acetolactate synthase, ahas1, ahas2, ahass, ahas ii, acetohydroxy acid synthetase, acetohydroxy acid synthase i, ahas3, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2 pyruvate = 2-acetolactate + CO2
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