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Information on EC 2.2.1.10 - 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase

for references in articles please use BRENDA:EC2.2.1.10
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IUBMB Comments
The enzyme plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. The enzyme can also catalyse the reaction of EC 4.1.2.13, fructose-bisphosphate aldolase.
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The expected taxonomic range for this enzyme is: Methanocaldococcus jannaschii
Synonyms
ADHS, 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid synthase, ADH synthase, ADHS, MJ0400, More, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
L-aspartate 4-semialdehyde + 1-deoxy-D-threo-hexo-2,5-diulose 6-phosphate = 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + 2,3-dioxopropyl phosphate
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