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Information on EC 2.1.2.1 - glycine hydroxymethyltransferase

for references in articles please use BRENDA:EC2.1.2.1
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IUBMB Comments
A pyridoxal-phosphate protein. Also catalyses the reaction of glycine with acetaldehyde to form L-threonine, and with 4-trimethylammoniobutanal to form 3-hydroxy-N6,N6,N6-trimethyl-L-lysine.
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The expected taxonomic range for this enzyme is: Archaea, Bacteria, Eukaryota
Synonyms
serine hydroxymethyltransferase, shmt1, shmt2, serine transhydroxymethylase, serine hydroxymethyl transferase, mitochondrial serine hydroxymethyltransferase, bsshmt, serine hydroxymethyltransferase 1, pvshmt, serine hydroxymethyltransferase 2, more
REACTION
REACTION DIAGRAM
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ORGANISM
UNIPROT
LITERATURE
5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine
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