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Information on EC 2.1.1.77 - protein-L-isoaspartate(D-aspartate) O-methyltransferase

for references in articles please use BRENDA:EC2.1.1.77
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IUBMB Comments
D-Aspartate (but not L-aspartate) residues in proteins can also act as acceptors. Previously also listed as EC 2.1.1.24.
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Word Map
The expected taxonomic range for this enzyme is: Eukaryota, Archaea, Bacteria
Synonyms
pcm-1, pcmt1, protein l-isoaspartyl methyltransferase, l-isoaspartyl methyltransferase, pimt1, protein-l-isoaspartate (d-aspartate) o-methyltransferase, protein l-isoaspartate (d-aspartate) o-methyltransferase, l-isoaspartyl o-methyltransferase, protein isoaspartyl methyltransferase, protein-l-isoaspartyl methyltransferase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
S-adenosyl-L-methionine + protein L-isoaspartate = S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
show the reaction diagram
D-aspartate (but not L-aspartate) residues in proteins can also act as acceptors
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