Reference on EC 2.1.1.4 - acetylserotonin O-methyltransferase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Axelrod, J.; Weissbach, H.
Purification and properties of hydroxyindole-O-methyl transferase
J. Biol. Chem.
236
211-213
1961
Bos taurus, Felis catus, Macaca mulatta
Suzuki, O.; Yagi, K.
A nonisotopic assay for acetylserotonin methyltransferase
Anal. Biochem.
88
580-586
1978
Gallus gallus, Frog, Rattus norvegicus
Kuwano, R.; Takahashi, Y.
Binding of S-adenosylhomocysteine to hydroxyindole O-methyltransferase
Biochim. Biophys. Acta
787
1-7
1984
Bos taurus
Sugden, D.; Klein, D.C.
Inactivation of rat pineal hydroxyindole-O-methyltransferase by disulfide-containing compounds
J. Biol. Chem.
262
6489-6493
1987
Rattus norvegicus
Sugden, D.; Cena, V.; Klein, D.C.
Hydroxyindole O-methyltransferase
Methods Enzymol.
142
590-596
1987
Bos taurus, Gallus gallus, Ovis aries, Rattus norvegicus
Morton, D.J.; Kock, N.
Some properties of pineal gland hydroxyindole-O-methyltransferase from black rhinoceros (Diceros bicornis)
J. Pineal Res.
8
35-40
1990
Diceros bicornis
Morton, D.J.
Mechanism of inhibition of bovine pineal gland hydroxyindole-O-methyltransferase (EC 2.1.1.4) by divalent cations
J. Pineal Res.
4
295-303
1987
Bos taurus
Sugden, D.; Voisin, P.; Klein, D.C.
Purification of rat pineal hydroxyindole-O-methyltransferase using S-adenosyl-L-homocysteine agarose chromatography
J. Pineal Res.
3
389-395
1986
Rattus norvegicus
Nakane, M.; Yokoyama, E.; Deguchi, T.
Species heterogeneity of pineal hydroxyindole-O-methyltransferase
J. Neurochem.
40
790-796
1983
Bos taurus, Gallus gallus
Birks, E.K.; Ewing, R.D.
Characterization of hydroxyindole-O-methyltransferase (HIOMT) from the pineal gland of chinook salmon (Oncorhynchus tshawytscha)
Gen. Comp. Endocrinol.
43
269-276
1981
Oncorhynchus tshawytscha
Kuwano, R.; Yoshida, Y.; Takahshim, Y.
Purification of bovine pineal hydroxyindole O-methyltransferase by immunoadsorption chromatography
J. Neurochem.
31
815-824
1978
Bos taurus
Nir, I.; Hirschmann, N.; Sulman, F.G.
Inhibition of pineal hydroxyindole-O-methyl transferase by pyridoxal-5-phosphate
Biochem. Pharmacol.
25
581-583
1976
Rattus norvegicus
Karahasanoglu, A.M.; Ozand, P.T.
The purification and properties of bovine pineal S-adenosylmethionine: N-acetylserotonin O-methyl transferase
J. Neurochem.
19
411-430
1972
Bos taurus
Tedesco, S.C.; Moron, D.J.; Reiter, R.J.
Hydroxyindole-O-methyltransferase activity in the pineal gland of the muskox (Ovibos moschatus)
J. Pineal Res.
16
121-126
1994
Ovibos moschatus
Benyassi, A.; Schwartz, C.; Ducouret, B.; Falcon, J.
Glucocorticoid receptors and serotonin N-acetyltransferase activity in the fish pineal organ
NeuroReport
12
889-892
2001
Oncorhynchus mykiss
Ribelayga, C.; Gauer, F.; Calgari, C.; Pevet, P.; Simonneaux, V.
Photoneural regulation of rat pineal hydroxyindole-O-methyltransferase (HIOMT) messenger ribonucleic acid expression: an analysis of its complex relationship with HIOMT activity
Endocrinology
140
1375-1384
1999
Rattus norvegicus
Bernard, M.; Donohue, S.J.; Klein, D.C.
Human hydroxyindole-O-methyltransferase in pineal gland, retina and Y79 retinoblastoma cells
Brain Res.
696
37-48
1995
Homo sapiens
Itoh, M.T.; Ishizuka, B.; Kudo, Y.; Fusama, S.; Amemiya, A.; Sumi, Y.
Detection of melatonin and serotonin N-acetyltransferase and hydroxyindole-O-methyltransferase activities in rat ovary
Mol. Cell. Endocrinol.
136
7-13
1997
Rattus norvegicus
Bernard, M.; Klein, D.C.
Retinoic acid increases hydroxyindole-O-methyltransferase activity and mRNA in human Y-79 retinoblastoma cells
J. Neurochem.
67
1032-1038
1996
Homo sapiens
Ishio, S.; Yamada, H.; Craft, C.M.; Moriyama, Y.
Hydroxyindole-O-methyltransferase is another target for L-glutamate-evoked inhibition of melatonin synthesis in rat pinealocytes
Brain Res.
850
73-78
1999
Rattus norvegicus
Lewy, H.; Massot, O.; Touitou, Y.
Magnetic field (50 Hz) increases N-acetyltransferase, hydroxy-indole-O-methyltransferase activity and melatonin release through an indirect pathway
Int. J. Radiat. Biol.
79
431-435
2003
Rattus norvegicus, Rattus norvegicus Wistar
Pozo, D.; Garcia-Maurino, S.; Guerrero, J.M.; Calvo, J.R.
mRNA expression of nuclear receptor RZR/RORalpha, melatonin membrane receptor MT, and hydroxindole-O-methyltransferase in different populations of human immune cells
J. Pineal Res.
37
48-54
2004
Homo sapiens
Olszanska, B.; Majewski, P.; Lewczuk, B.; Stepinska, U.
Melatonin and its synthesizing enzymes (arylalkylamine N-acetyltransferase-like and hydroxyindole-O-methyltransferase) in avian eggs and early embryos
J. Pineal Res.
43
310-318
2007
Coturnix japonica
Sanchez-Hidalgo, M.; de la Lastra, C.A.; Carrascosa-Salmoral, M.P.; Naranjo, M.C.; Gomez-Corvera, A.; Caballero, B.; Guerrero, J.M.
Age-related changes in melatonin synthesis in rat extrapineal tissues
Exp. Gerontol.
44
328-334
2009
Rattus norvegicus
Bernard, M.; Voisin, P.
Photoreceptor-specific expression, light-dependent localization, and transcriptional targets of the zinc-finger protein Yin Yang 1 in the chicken retina
J. Neurochem.
105
595-604
2008
Gallus gallus
Konturek, P.C.; Konturek, S.J.; Burnat, G.; Brzozowski, T.; Brzozowska, I.; Reiter, R.J.
Dynamic physiological and molecular changes in gastric ulcer healing achieved by melatonin and its precursor L-tryptophan in rats
J. Pineal Res.
45
180-190
2008
Rattus norvegicus
Zmijewski, M.A.; Sweatman, T.W.; Slominski, A.T.
The melatonin-producing system is fully functional in retinal pigment epithelium (ARPE-19)
Mol. Cell. Endocrinol.
307
211-216
2009
Homo sapiens
Velarde, E.; Cerda-Reverter, J.M.; Alonso-Gomez, A.L.; Sanchez, E.; Isorna, E.; Delgado, M.J.
Melatonin-synthesizing enzymes in pineal, retina, liver, and gut of the goldfish (Carassius): mRNA expression pattern and regulation of daily rhythms by lighting conditions
Chronobiol. Int.
27
1178-1201
2010
Carassius auratus
Shimozuma, M.; Tokuyama, R.; Tatehara, S.; Umeki, H.; Ide, S.; Mishima, K.; Saito, I.; Satomura, K.
Expression and cellular localizaion of melatonin-synthesizing enzymes in rat and human salivary glands
Histochem. Cell Biol.
135
389-396
2011
Homo sapiens, Rattus norvegicus
Fukuda, T.; Akiyama, N.; Ikegami, M.; Takahashi, H.; Sasaki, A.; Oka, H.; Komori, T.; Tanaka, Y.; Nakazato, Y.; Akimoto, J.; Tanaka, M.; Okada, Y.; Saito, S.
Expression of hydroxyindole-O-methyltransferase enzyme in the human central nervous system and in pineal parenchymal cell tumors
J. Neuropathol. Exp. Neurol.
69
498-510
2010
Homo sapiens (P46597), Homo sapiens
Byeon, Y.; Choi, G.H.; Lee, H.Y.; Back, K.
Melatonin biosynthesis requires N-acetylserotonin methyltransferase activity of caffeic acid O-methyltransferase in rice
J. Exp. Bot.
66
6917-6925
2015
Oryza sativa (Q6ZD89), Oryza sativa
Azam, S.; Saroosh, A.; Zaman, N.; Raza, S.
Role of N-acetylserotonin O-methyltransferase in bipolar disorders and its dynamics
J. Mol. Liq.
182
25-31
2013
Homo sapiens
-
Park, S.; Byeon, Y.; Kim, Y.S.; Back, K.
Kinetic analysis of purified recombinant rice N-acetylserotonin methyltransferase and peak melatonin production in etiolated rice shoots
J. Pineal Res.
54
139-144
2013
Oryza sativa
Byeon, Y.; Back, K.
Melatonin synthesis in rice seedlings in vivo is enhanced at high temperatures and under dark conditions due to increased serotonin N-acetyltransferase and N-acetylserotonin methyltransferase activities
J. Pineal Res.
56
189-195
2014
Oryza sativa
Byeon, Y.; Lee, H.Y.; Lee, K.; Back, K.
Caffeic acid O-methyltransferase is involved in the synthesis of melatonin by methylating N-acetylserotonin in Arabidopsis
J. Pineal Res.
57
219-227
2014
Arabidopsis thaliana (Q9T003), Arabidopsis thaliana, Arabidopsis thaliana Col-0 (Q9T003)
Byeon, Y.; Lee, H.J.; Lee, H.Y.; Back, K.
Cloning and functional characterization of the Arabidopsis N-acetylserotonin O-methyltransferase responsible for melatonin synthesis
J. Pineal Res.
60
65-73
2015
Arabidopsis thaliana (Q9T003), Arabidopsis thaliana, Arabidopsis thaliana Col-0 (Q9T003)
Wang, L.; Zhang, T.; Li, J.; He, C.; He, H.; Zhang, J.
Catalytic mechanism of human N-acetylserotonin methyltransferase: a theoretical investigation
Mol. Phys.
113
3438-3449
2015
Homo sapiens (P46597)
-
Byeon, Y.; Back, K.
Melatonin production in Escherichia coli by dual expression of serotonin N-acetyltransferase and caffeic acid O-methyltransferase
Appl. Microbiol. Biotechnol.
100
6683-6691
2016
Oryza sativa Japonica Group (Q6ZD89)
Betti, L.; Palego, L.; Demontis, G.C.; Miraglia, F.; Giannaccini, G.
Hydroxyindole-O-methyltransferase (HIOMT) activity in the retina of melatonin-proficient mice
Heliyon
5
e02417
2019
Mus musculus (D3KU66), Mus musculus
Byeon, Y.; Back, K.
Low melatonin production by suppression of either serotonin N-acetyltransferase or N-acetylserotonin methyltransferase in rice causes seedling growth retardation with yield penalty, abiotic stress susceptibility, and enhanced coleoptile growth under anoxi
J. Pineal Res.
60
348-359
2016
Oryza sativa
Wei, Y.; Liu, G.; Chang, Y.; Lin, D.; Reiter, R.J.; He, C.; Shi, H.
Melatonin biosynthesis enzymes recruit WRKY transcription factors to regulate melatonin accumulation and transcriptional activity on W-box in cassava
J. Pineal Res.
65
e12487
2018
Manihot esculenta (A0A193DSQ2), Manihot esculenta
Lee, K.; Hwang, O.J.; Reiter, R.J.; Back, K.
Flavonoids inhibit both rice and sheep serotonin N-acetyltransferases and reduce melatonin levels in plants
J. Pineal Res.
65
e12512
2018
Oryza sativa Japonica Group (Q6ZD89)
Coelho, L.A.; Andrade-Silva, J.; Motta-Teixeira, L.C.; Amaral, F.G.; Reiter, R.J.; Cipolla-Neto, J.
The absence of pineal melatonin abolishes the daily rhythm of Tph1 (tryptophan hydroxylase 1), Asmt (acetylserotonin O-methyltransferase), and Aanat (aralkylamine N-acetyltransferase) mRNA expressions in rat testes
Mol. Neurobiol.
56
7800-7809
2019
Rattus norvegicus (B3GSH5)
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