Reference on EC 2.1.1.361 - [histone H4]-lysine20 N-methyltransferase
Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Zhang, X.; Bruice, T.
Product specificity and mechanism of protein lysine methyltransferases: Insights from the histone lysine methyltransferase SET8
Biochemistry
47
6671-6677
2008
Homo sapiens
Kudithipudi, S.; Dhayalan, A.; Kebede, A.F.; Jeltsch, A.
The SET8 H4K20 protein lysine methyltransferase has a long recognition sequence covering seven amino acid residues
Biochimie
94
2212-2218
2012
Homo sapiens
Tryndyak, V.P.; Kovalchuk, O.; Pogribny, I.P.
Loss of DNA methylation and histone H4 lysine 20 trimethylation in human breast cancer cells is associated with aberrant expression of DNA methyltransferase 1, Suv4-20h2 histone methyltransferase and methyl-binding proteins
Cancer Biol. Ther.
5
65-70
2006
Homo sapiens (Q86Y97), Homo sapiens
Wu, S.; Rice, J.C.
A new regulator of the cell cycle the PR-Set7 histone methyltransferase
Cell Cycle
10
68-72
2011
Homo sapiens
Chen, X.; Ding, X.; Wu, Q.; Qi, J.; Zhu, M.; Miao, C.
Monomethyltransferase SET8 facilitates hepatocellular carcinoma growth by enhancing aerobic glycolysis
Cell Death Dis.
10
312
2019
Homo sapiens (Q9NQR1)
Tanaka, H.; Takebayashi, S.I.; Sakamoto, A.; Igata, T.; Nakatsu, Y.; Saitoh, N.; Hino, S.; Nakao, M.
The SETD8/PR-Set7 methyltransferase functions as a barrier to prevent senescence-associated metabolic remodeling
Cell Rep.
18
2148-2161
2017
Homo sapiens (Q9NQR1)
Fang, J.; Feng, Q.; Ketel, C.S.; Wang, H.; Cao, R.; Xia, L.; Erdjument-Bromage, H.; Tempst, P.; Simon, J.A.; Zhang, Y.
Purification and functional characterization of SET8, a nucleosomal histone H4-lysine 20-specific methyltransferase
Curr. Biol.
12
1086-1099
2002
Homo sapiens (Q9NQR1), Homo sapiens, Drosophila melanogaster (Q9VFK6)
Delaney, C.E.; Chen, A.T.; Graniel, J.V.; Dumas, K.J.; Hu, P.J.
A histone H4 lysine 20 methyltransferase couples environmental cues to sensory neuron control of developmental plasticity
Development
144
1273-1282
2017
Caenorhabditis elegans (Q09265)
Xiao, B.; Jing, C.; Kelly, G.; Walker, P.A.; Muskett, F.W.; Frenkiel, T.A.; Martin, S.R.; Sarma, K.; Reinberg, D.; Gamblin, S.J.; Wilson, J.R.
Specificity and mechanism of the histone methyltransferase Pr-Set7
Genes Dev.
19
1444-1454
2005
Homo sapiens
Wu, S.; Wang, W.; Kong, X.; Congdon, L.M.; Yokomori, K.; Kirschner, M.W.; Rice, J.C.
Dynamic regulation of the PR-Set7 histone methyltransferase is required for normal cell cycle progression
Genes Dev.
24
2531-2542
2010
Homo sapiens (Q9NQR1)
Sakaguchi, A.; Karachentsev, D.; Seth-Pasricha, M.; Druzhinina, M.; Steward, R.
Functional characterization of the Drosophila Hmt4-20/Suv4-20 histone methyltransferase
Genetics
179
317-322
2008
Drosophila melanogaster (Q9W5E0)
Houston, S.I.; McManus, K.J.; Adams, M.M.; Sims, J.K.; Carpenter, P.B.; Hendzel, M.J.; Rice, J.C.
Catalytic function of the PR-Set7 histone H4 lysine 20 monomethyltransferase is essential for mitotic entry and genomic stability
J. Biol. Chem.
283
19478-19488
2008
Homo sapiens (Q9NQR1)
Kapoor-Vazirani, P.; Vertino, P.M.
A dual role for the histone methyltransferase PR-SET7/SETD8 and histone H4 lysine 20 monomethylation in the local regulation of RNA polymerase II pausing
J. Biol. Chem.
289
7425-7437
2014
Homo sapiens (Q9NQR1)
Girish, T.; McGinty, R.; Tan, S.
Multivalent interactions by the Set8 histone methyltransferase with its nucleosome substrate
J. Mol. Biol.
428
1531-1543
2016
Homo sapiens
Nishioka, K.; Rice, J.C.; Sarma, K.; Erdjument-Bromage, H.; Werner, J.; Wang, Y.; Chuikov, S.; Valenzuela, P.; Tempst, P.; Steward, R.; Lis, J.T.; Allis, C.D.; Reinberg, D.
PR-Set7 is a nucleosome-specific methyltransferase that modifies lysine 20 of histone H4 and is associated with silent chromatin
Mol. Cell
9
1201-1213
2002
Drosophila melanogaster, Homo sapiens (Q9NQR1), Homo sapiens
Tardat, M.; Brustel, J.; Kirsh, O.; Lefevbre, C.; Callanan, M.; Sardet, C.; Julien, E.
The histone H4 Lys 20 methyltransferase PR-Set7 regulates replication origins in mammalian cells
Nat. Cell Biol.
12
1086-1093
2010
Homo sapiens (Q9NQR1)
Zouaz, A.; Fernando, C.; Perez, Y.; Sardet, C.; Julien, E.; Grimaud, C.
Cell-cycle regulation of non-enzymatic functions of the Drosophila methyltransferase PR-Set7
Nucleic Acids Res.
46
2834-2849
2018
Drosophila melanogaster (Q9VFK6)
Liao, T.; Wang, Y.J.; Hu, J.Q.; Wang, Y.; Han, L.T.; Ma, B.; Shi, R.L.; Qu, N.; Wei, W.J.; Guan, Q.; Xiang, J.; Chen, J.Y.; Sun, G.H.; Li, D.S.; Mu, X.M.; Ji, Q.H.
Histone methyltransferase KMT5A gene modulates oncogenesis and lipid metabolism of papillary thyroid cancer in vitro
Oncol. Rep.
39
2185-2192
2018
Homo sapiens (Q9NQR1)
Spektor, T.M.; Congdon, L.M.; Veerappan, C.S.; Rice, J.C.
The UBC9 E2 SUMO conjugating enzyme binds the PR-Set7 histone methyltransferase to facilitate target gene repression
PLoS ONE
6
e22785
2011
Homo sapiens (Q9NQR1), Homo sapiens
Weirich, S.; Kusevic, D.; Kudithipudi, S.; Jeltsch, A.
Investigation of the methylation of Numb by the SET8 protein lysine methyltransferase
Sci. Rep.
5
13813
2015
Homo sapiens (Q9NQR1)
html completed
