Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

Reference on EC 2.1.1.35 - tRNA (uracil54-C5)-methyltransferase

Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Björk, G.R.; Svensson, I.
Studies on microbial RNA. Fractionation of tRNA methylases from Saccharomyces cerevisiae
Eur. J. Biochem.
9
207-215
1969
Saccharomyces cerevisiae, Saccharomyces cerevisiae D84
Manually annotated by BRENDA team
Hurwitz, J.; Gold, M.; Anders, M.
The enzymatic methylation of ribonucleic acid and deoxyribonucleic acid. III. Purification of soluble ribonucleic acid-methylating enzymes
J. Biol. Chem.
239
3462-3473
1964
Escherichia coli
Manually annotated by BRENDA team
Hurwitz, J.; Gold, M.; Anders, M.
The enzymatic methylation of ribonucleic acid and deoxyribonucleic acid. IV. The properties of the soluble ribonucleic acid-methylating enzymes
J. Biol. Chem.
239
3474-3482
1964
Escherichia coli
Manually annotated by BRENDA team
Cimino, F.; Traboni, C.; Colonna, A.; Izzo, P.; Salvatore, F.
Purification and properties of several transfer RNA methyltransferases from S. typhimurium
Mol. Cell. Biochem.
36
95-104
1981
Salmonella enterica subsp. enterica serovar Typhimurium
Manually annotated by BRENDA team
Svensson, I.; Björk, G.R.; Lundahl, P.
Studies on microbial RNA. Properties of tRNA methylases from Saccharomyces cerevisiae
Eur. J. Biochem.
9
216-221
1969
Saccharomyces cerevisiae, Saccharomyces cerevisiae D84
Manually annotated by BRENDA team
Shugart, L.; Chastain, B.
Escherichia coli tRNA (uracil-5-)-methyltransferase: Inhibition by analogues of adenosylhomocysteine
Enzyme
24
353-357
1979
Escherichia coli
Manually annotated by BRENDA team
Greenberg, R.; Dudock, B.
Isolation and characterization of m5U-methyltransferase from Escherichia coli
J. Biol. Chem.
255
8296-8302
1980
Escherichia coli, Escherichia coli MRE 600, Escherichia coli SN01
Manually annotated by BRENDA team
Greenberg, R.; Dudock, B.
Bacterial tRNA methyltransferases
Methods Enzymol.
59
190-203
1979
Bacillus cereus, Bacillus subtilis, Enterococcus faecalis, Escherichia coli, Escherichia coli MRE 600
Manually annotated by BRENDA team
Gustafsson, C.; Björk, G.R.
The tRNA-(m5U54)-methyltransferase of Escherichia coli is present in two forms in vivo, one of which is present as bound to tRNA and to a 3-end fragment of 16S rRNA
J. Biol. Chem.
268
1326-1331
1993
Escherichia coli, Escherichia coli 1100
Manually annotated by BRENDA team
Shugart, L.
Kinetic studies of Escherichia coli transfer RNA (uracil-5-)-methyltransferase
Biochemistry
17
1068-1072
1978
Escherichia coli, Escherichia coli K12MO7
Manually annotated by BRENDA team
Santi, D.V.; Hardy, L.W.
Catalytic mechanism and inhibition of tRNA (uracil-5-)methyltransferase: Evidence for covalent catalysis
Biochemistry
26
8599-8606
1987
Escherichia coli, Escherichia coli GB-1-5-39 / pTN102
Manually annotated by BRENDA team
Gu, X.; Santi, D.V.
The T-arm of tRNA is a substrate for tRNA (m5U54)-methyltransferase
Biochemistry
30
2999-3002
1991
Escherichia coli
Manually annotated by BRENDA team
Ny, T.; Lindström, P.H.R.; Hagervall, T.G.; Björk, G.R.
Purification of transfer RNA (m5U54)-methyltransferase from Escherichia coli. Association with RNA
Eur. J. Biochem.
177
467-475
1988
Escherichia coli, Escherichia coli C600 / pTN106
Manually annotated by BRENDA team
Kealey, J.T.; Lee, S.; Floss, H.G.; Santi, D.V.
Stereochemistry of methyl transfer catalyzed by tRNA (m5U54)-methyltransferase--evidence for a single displacement mechanism
Nucleic Acids Res.
19
6465-6468
1991
Escherichia coli
Manually annotated by BRENDA team
Tscherne, J.S.; Wainfan, E.
Selective inhibition of uracil tRNA methylases of E. coli by ethionine
Nucleic Acids Res.
5
451-461
1978
Escherichia coli
Manually annotated by BRENDA team
Kealey, J.T.; Gu, X.; Santi, D.V.
Enzymatic mechanism of tRNA (m5U54)methyltransferase
Biochimie
76
1133-1142
1994
Escherichia coli
Manually annotated by BRENDA team
Kealey, J.T.; Santi, D.V.
High-level expression and rapid purification of tRNA (m5U54)-methyltransferase
Protein Expr. Purif.
5
149-152
1994
Escherichia coli, Escherichia coli GB-1-5-39 / pTN102
Manually annotated by BRENDA team
Gu, X.; Matsuda, A.; Ivanetich, K.M.; Santi, D.V.
Interaction of tRNA (uracil-5-)-methyltransferase with NO2Ura-tRNA
Nucleic Acids Res.
24
1059-1064
1996
Escherichia coli
Manually annotated by BRENDA team
Kealey, J.T.; Santi, D.V.
Stereochemistry of tRNA(m5U54)-methyltransferase catalysis: 19F NMR spectroscopy of an enzyme-FUraRNA covalent complex
Biochemistry
34
2441-2446
1995
Escherichia coli
Manually annotated by BRENDA team
Gu, X.; Ofengand, J.; Santi, D.V.
In vitro methylation of Escherichia coli 16S rRNA by tRNA (m5U54)-methyltransferase
Biochemistry
33
2255-2261
1994
Escherichia coli
Manually annotated by BRENDA team
Guenther, R.H.; Bakal, R.S.; Forrest, B.; Chen, Y.; Sengupta, R.; Nawrot, B.; Sochacka, E.; Jankowska, J.; Kraszewski, A.; Malkiewicz, A.; Agris, P.F.
Aminoacyl-tRNA synthetase and U54 methyltransferase recognize conformations of the yeast tRNAPhe anticodon and T stem/loop domain
Biochimie
76
1143-1151
1994
Escherichia coli
Manually annotated by BRENDA team
Sengupta, R.; Vainauskas, S.; Yarian, C.; Sochacka, E.; Malkiewicz, A.; Guenther, R.H.; Koshlap, K.M.; Agris, P.F.
Modified constructs of the tRNA TPsiC domain to probe substrate conformational requirements of m1A58 and m5U54 tRNA methyltransferases
Nucleic Acids Res.
28
1374-1380
2000
Escherichia coli, Escherichia coli GRB822
Manually annotated by BRENDA team
Gu, X.; Ivanetich, K.M.; Santi, D.V.
Recognition of the T-arm of tRNA by tRNA (m5U54)-methyltransferase is not sequence specific
Biochemistry
35
11652-11659
1996
Escherichia coli
Manually annotated by BRENDA team
Nordlund, M.E.; Johansson, J.O.M.; von Pawel-Rammingen, U.; Byström, A.S.
Identification of the TRM2 gene encoding the tRNA(m5U54)methyltransferase of Saccharomyces cerevisiae
RNA
6
844-860
2000
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Johansson, M.J.O.; Byström, A.S.
Dual function of the tRNA(m5U54)methyltransferase in tRNA maturation
RNA
8
324-335
2002
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Urbonavicius, J.; Jaeger, G.; Bjoerk, G.R.
Amino acid residues of the Escherichia coli tRNA(m5U54)methyltransferase (TrmA) critical for stability, covalent binding of tRNA and enzymatic activity
Nucleic Acids Res.
35
3297-3305
2007
Escherichia coli
Manually annotated by BRENDA team
Alian, A.; Lee, T.T.; Griner, S.L.; Stroud, R.M.; Finer-Moore, J.
Structure of a TrmA-RNA complex: A consensus RNA fold contributes to substrate selectivity and catalysis in m5U methyltransferases
Proc. Natl. Acad. Sci. USA
105
6876-6881
2008
Escherichia coli (P23003)
Manually annotated by BRENDA team
Urbonavicius, J.; Auxilien, S.; Walbott, H.; Trachana, K.; Golinelli-Pimpaneau, B.; Brochier-Armanet, C.; Grosjean, H.
Acquisition of a bacterial RumA-type tRNA(uracil-54, C5)-methyltransferase by Archaea through an ancient horizontal gene transfer
Mol. Microbiol.
67
323-335
2008
Pyrococcus abyssi
Manually annotated by BRENDA team
Walbott, H.; Leulliot, N.; Grosjean, H.; Golinelli-Pimpaneau, B.
The crystal structure of Pyrococcus abyssi tRNA (uracil-54, C5)-methyltransferase provides insights into its tRNA specificity
Nucleic Acids Res.
36
4929-4940
2008
Pyrococcus abyssi (Q9UZR7)
Manually annotated by BRENDA team
Auxilien, S.; Rasmussen, A.; Rose, S.; Brochier-Armanet, C.; Husson, C.; Fourmy, D.; Grosjean, H.; Douthwaite, S.
Specificity shifts in the rRNA and tRNA nucleotide targets of archaeal and bacterial m5U methyltransferases
RNA
17
45-53
2011
Pyrococcus abyssi
Manually annotated by BRENDA team
Carter, J.M.; Emmett, W.; Rdl Mozos, I.; Kotter, A.; Helm, M.; Ule, J.; Hussain, S.
FICC-Seq A method for enzyme-specified profiling of methyl-5-uridine in cellular RNA
Nucleic Acids Res.
47
e113
2019
Homo sapiens (Q8IZ69), Homo sapiens
Manually annotated by BRENDA team