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Disease on EC 2.1.1.321 - type III protein arginine methyltransferase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Breast Neoplasms
Automethylation of protein arginine methyltransferase 7 and its impact on breast cancer progression.
PRMT7 contributes to the metastasis phenotype in human non-small-cell lung cancer cells possibly through the interaction with HSPA5 and EEF2.
Protein arginine methyltransferase 7 promotes breast cancer cell invasion through the induction of MMP9 expression.
Carcinoma, Hepatocellular
S-adenosylmethionine:protein methyltransferases in hepatomas.
Neoplasm Metastasis
Mammalian protein arginine methyltransferase 7 (PRMT7) specifically targets RXR sites in lysine- and arginine-rich regions.
PRMT7 contributes to the metastasis phenotype in human non-small-cell lung cancer cells possibly through the interaction with HSPA5 and EEF2.
Structural insight into arginine methylation by the mouse protein arginine methyltransferase 7: a zinc finger freezes the mimic of the dimeric state into a single active site.
Substrate specificity of human protein arginine methyltransferase 7 (PRMT7): the importance of acidic residues in the double E loop.