show all | hide all No of entries

Information on EC 2.1.1.301 - cypemycin N-terminal methyltransferase

for references in articles please use BRENDA:EC2.1.1.301
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.301 cypemycin N-terminal methyltransferase
IUBMB Comments
The enzyme, isolated from the bacterium Streptomyces sp. OH-4156, can methylate a variety of linear oligopeptides, cyclic peptides such as nisin and haloduracin, and the epsilon-amino group of lysine . Cypemycin is a peptide antibiotic, a member of the linaridins, a class of posttranslationally modified ribosomally synthesized peptides.
Specify your search results
Select one or more organisms in this record:
Word Map
  • 2.1.1.301
  • multidomain
  • disassembly
  • f-actin
  • guidance
  • repulsive
  • semaphorins
  • plexins
  • flavoprotein
  • flavoenzyme
  • nadph-dependent
  • fad-containing
  • mical-1
  • semaphorin-plexin
  • calponine
The expected taxonomic range for this enzyme is: Streptomyces
Synonyms
s-adenosyl methionine-dependent methyltransferase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2 S-adenosyl-L-methionine + N-terminal L-alanine-[cypemycin] = 2 S-adenosyl-L-homocysteine + N-terminal N,N-dimethyl-L-alanine-[cypemycin]
show the reaction diagram
-
-
-
-
Select items on the left to see more content.