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Information on EC 2.1.1.281 - phenylpyruvate C3-methyltransferase

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EC Tree
     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.281 phenylpyruvate C3-methyltransferase
IUBMB Comments
The enzyme from the bacterium Streptomyces hygroscopicus NRRL3085 is involved in synthesis of the nonproteinogenic amino acid (2S,3S)-beta-methyl-phenylalanine, a building block of the antibiotic mannopeptimycin.
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The expected taxonomic range for this enzyme is: Streptomyces hygroscopicus
Synonyms
MppJ, phenylpyruvate Cbeta-methyltransferase, phenylpyruvate methyltransferase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
S-adenosyl-L-methionine + 3-phenylpyruvate = S-adenosyl-L-homocysteine + (3S)-2-oxo-3-phenylbutanoate
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