Reference on EC 2.1.1.260 - rRNA small subunit pseudouridine methyltransferase Nep1
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Eschrich, D.; Buchhaupt, M.; Koetter, P.; Entian, K.D.
Nep1p (Emg1p), a novel protein conserved in eukaryotes and archaea, is involved in ribosome biogenesis
Curr. Genet.
40
326-338
2002
Saccharomyces cerevisiae, Homo sapiens, [Candida] glabrata (Q96UP2), Candida albicans (Q9P8P7), Candida albicans, [Candida] glabrata CBS 138 (Q96UP2), Saccharomyces cerevisiae CEN.PK2, Candida albicans RM1000 (Q9P8P7)
Taylor, A.B.; Meyer, B.; Leal, B.Z.; Koetter, P.; Schirf, V.; Demeler, B.; Hart, P.J.; Entian, K.D.; Woehnert, J.
The crystal structure of Nep1 reveals an extended SPOUT-class methyltransferase fold and a pre-organized SAM-binding site
Nucleic Acids Res.
36
1542-1554
2008
Methanocaldococcus jannaschii (Q57977), Methanocaldococcus jannaschii DSM 2661 (Q57977)
Wurm, J.; Meyer, B.; Bahr, U.; Held, M.; Frolow, O.; Koetter, P.; Engels, J.; Heckel, A.; Karas, M.; Entian, K.; Woehnert, J.
The ribosome assembly factor Nep1 responsible for Bowen-Conradi syndrome is a pseudouridine-N1-specific methyltransferase
Nucleic Acids Res.
38
2387-2398
2010
Homo sapiens, Methanocaldococcus jannaschii
Meyer, B.; Wurm, J.P.; Koetter, P.; Leisegang, M.S.; Schilling, V.; Buchhaupt, M.; Held, M.; Bahr, U.; Karas, M.; Heckel, A.; Bohnsack, M.T.; Woehnert, J.; Entian, K.D.
The Bowen-Conradi syndrome protein Nep1 (Emg1) has a dual role in eukaryotic ribosome biogenesis, as an essential assembly factor and in the methylation of psi1191 in yeast 18S rRNA
Nucleic Acids Res.
39
1526-1537
2011
Homo sapiens, Saccharomyces cerevisiae
Thomas, S.R.; Keller, C.A.; Szyk, A.; Cannon, J.R.; Laronde-Leblanc, N.A.
Structural insight into the functional mechanism of Nep1/Emg1 N1-specific pseudouridine methyltransferase in ribosome biogenesis
Nucleic Acids Res.
39
2445-2457
2011
Saccharomyces cerevisiae, Archaeoglobus fulgidus (O29524)
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