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Information on EC 2.1.1.259 - [fructose-bisphosphate aldolase]-lysine N-methyltransferase

for references in articles please use BRENDA:EC2.1.1.259
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IUBMB Comments
The enzyme methylates a conserved lysine in the C-terminal part of higher plant fructose-bisphosphate aldolase (EC 4.1.2.13). The enzyme from pea (Pisum sativum) also methylates Lys-14 in the large subunits of hexadecameric higher plant ribulose-bisphosphate-carboxylase (EC 4.1.1.39) , but that from Arabidopsis thaliana does not.
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The enzyme appears in viruses and cellular organisms
Reaction Schemes
3
+
[fructose-bisphosphate aldolase]-L-lysine
=
3
+
[fructose-bisphosphate aldolase]-N6,N6,N6-trimethyl-L-lysine
Synonyms
large subunit of Rubisco methyltransferase, LSMT, LSMT-L, protein-lysine methyltransferase-like, Ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit epsilonN-methyltransferase, Ribulose-bisphosphate-carboxylase/oxygenase N-methyltransferase, Rubisco methyltransferase, S-adenosyl-L-methionine:[3-phospho-D-glycerate-carboxy-lyase (dimerizing)]-lysine 6-N-methyltransferase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
3 S-adenosyl-L-methionine + [fructose-bisphosphate aldolase]-L-lysine = 3 S-adenosyl-L-homocysteine + [fructose-bisphosphate aldolase]-N6,N6,N6-trimethyl-L-lysine
show the reaction diagram
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