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Information on EC - [methyl-Co(III) methylamine-specific corrinoid protein]:coenzyme M methyltransferase

for references in articles please use BRENDA:EC2.1.1.247
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EC Tree
IUBMB Comments
Contains zinc . The enzyme, which is involved in methanogenesis from mono-, di-, and trimethylamine, catalyses the transfer of a methyl group bound to the cobalt cofactor of several corrinoid proteins (mono-, di-, and trimethylamine-specific corrinoid proteins, cf. EC, methylamine---corrinoid protein Co-methyltransferase, EC, dimethylamine---corrinoid protein Co-methyltransferase, and EC, trimethylamine---corrinoid protein Co-methyltransferase) to coenzyme M, forming the substrate for EC, coenzyme-B sulfoethylthiotransferase, the enzyme that catalyses the final step in methanogenesis.
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The expected taxonomic range for this enzyme is: Methanosarcinaceae
Reaction Schemes
a [methyl-Co(III) methylamine-specific corrinoid protein]
a [Co(I) methylamine-specific corrinoid protein]
methylcorrinoid:com methyltransferase, corrinoid:coenzyme m methyltransferase, methylcorrinoid:coenzyme m methyltransferase, more
a [methyl-Co(III) methylamine-specific corrinoid protein] + CoM = methyl-CoM + a [Co(I) methylamine-specific corrinoid protein]
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