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Information on EC 2.1.1.229 - tRNA (carboxymethyluridine34-5-O)-methyltransferase

for references in articles please use BRENDA:EC2.1.1.229
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EC Tree
IUBMB Comments
The enzyme catalyses the posttranslational modification of uridine residues at the wobble position 34 of the anticodon loop of tRNA.
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Word Map
  • 2.1.1.229
  • wobble
  • methyltransferases
  • 5-methoxycarbonylmethyluridine
  • gene-specific
  • trnagluuuc
  • anticodon
  • translationally
  • ribonucleotide
  • medicine
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Reaction Schemes
+
carboxymethyluridine34 in tRNA
=
+
5-(2-methoxy-2-oxoethyl)uridine34 in tRNA
Synonyms
trna methyltransferase 9, trm9p, trm9-trm112, yml014w, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
S-adenosyl-L-methionine + carboxymethyluridine34 in tRNA = S-adenosyl-L-homocysteine + 5-(2-methoxy-2-oxoethyl)uridine34 in tRNA
show the reaction diagram
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