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Information on EC 2.1.1.200 - tRNA (cytidine32/uridine32-2'-O)-methyltransferase

for references in articles please use BRENDA:EC2.1.1.200
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IUBMB Comments
In Escherichia coli YfhQ is the only methyltransferase responsible for the formation of 2'-O-methylcytidine32 in tRNA. No methylation of cytosine34 in tRNALeu(CAA). In vitro the enzyme 2-O-methylates cytidine32 of tRNASer1 and uridine32 of tRNAGln2.
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The expected taxonomic range for this enzyme is: Bacteria, Archaea
Synonyms
trmet(xm32), trna:cm32/um32 methyltransferase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
S-adenosyl-L-methionine + cytidine32 in tRNA = S-adenosyl-L-homocysteine + 2'-O-methylcytidine32 in tRNA
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S-adenosyl-L-methionine + uridine32 in tRNA = S-adenosyl-L-homocysteine + 2'-O-methyluridine32 in tRNA
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