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Information on EC 2.1.1.190 - 23S rRNA (uracil1939-C5)-methyltransferase

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IUBMB Comments
The enzyme specifically methylates uracil1939 at C5 in 23S rRNA . The enzyme contains an [4Fe-4S] cluster coordinated by four conserved cysteine residues .
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The enzyme appears in viruses and cellular organisms
Reaction Schemes
Synonyms
m5U methyltransferase, Mcap0476, RlmCD, RlmD, RlmFO, RNA m5U methyltransferase, RNA uridine methyltransferase A, RumA, SP 1029, YefA, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
S-adenosyl-L-methionine + uracil1939 in 23S rRNA = S-adenosyl-L-homocysteine + 5-methyluracil1939 in 23S rRNA
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