show all | hide all No of entries

Information on EC 2.1.1.188 - 23S rRNA (guanine748-N1)-methyltransferase

for references in articles please use BRENDA:EC2.1.1.188
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
IUBMB Comments
The enzyme specifically methylates guanine748 at N1 in 23S rRNA. The methyltransferase RlmAII confers resistance to the macrolide antibiotic tylosin in the drug-producing strain Streptomyces fradiae .
Specify your search results
Select one or more organisms in this record:
Word Map
The enzyme appears in viruses and cellular organisms
Reaction Schemes
Synonyms
methyltransferase RlmAII, RlmA II, RlmA(II), RlmAII, rRNA large subunit methyltransferase II, TlrB, tylosin resistance methyltransferase RlmA(II), tylosin-resistance methyltransferase RlmA(II), more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
S-adenosyl-L-methionine + guanine748 in 23S rRNA = S-adenosyl-L-homocysteine + N1-methylguanine748 in 23S rRNA
show the reaction diagram
-
-
-
-
Select items on the left to see more content.