show all | hide all No of entries

Information on EC 2.1.1.182 - 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase

for references in articles please use BRENDA:EC2.1.1.182
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
IUBMB Comments
KsgA introduces the most highly conserved ribosomal RNA modification, the dimethylation of adenine1518 and adenine1519 in 16S rRNA. Strains lacking the methylase are resistant to kasugamycin .
Specify your search results
Select one or more organisms in this record:
The enzyme appears in viruses and cellular organisms
Reaction Schemes
4
+
adenine1518/adenine1519 in 16S rRNA
=
4
+
N6-dimethyladenine1518/N6-dimethyladenine1519 in 16S rRNA
Synonyms
ksga methyltransferase, s-adenosylmethionine-6-n',n'-adenosyl (rrna) dimethyltransferase, 16s rrna adenine dimethyltransferase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
4 S-adenosyl-L-methionine + adenine1518/adenine1519 in 16S rRNA = 4 S-adenosyl-L-homocysteine + N6-dimethyladenine1518/N6-dimethyladenine1519 in 16S rRNA
show the reaction diagram
Select items on the left to see more content.