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Information on EC 2.1.1.173 - 23S rRNA (guanine2445-N2)-methyltransferase

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IUBMB Comments
The enzyme methylates 23S rRNA in vitro, assembled 50S subunits are not a substrate . The enzyme specifically methylates guanine2445 at N2 in 23S rRNA.
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The enzyme appears in viruses and cellular organisms
Reaction Schemes
Synonyms
rlmkl, smu472, ribosomal large subunit methyltransferase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
S-adenosyl-L-methionine + guanine2445 in 23S rRNA = S-adenosyl-L-homocysteine + N2-methylguanine2445 in 23S rRNA
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