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Information on EC 2.1.1.162 - glycine/sarcosine/dimethylglycine N-methyltransferase

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IUBMB Comments
Unlike EC 2.1.1.156 (glycine/sarcosine N-methyltransferase), EC 2.1.1.157 (sarcosine/dimethylglycine N-methyltransferase) and EC 2.1.1.161 (dimethylglycine N-methyltransferase), this enzyme, from the halophilic methanoarchaeon Methanohalophilus portucalensis, can methylate glycine and all of its intermediates to form the compatible solute betaine .
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The expected taxonomic range for this enzyme is: Methanohalophilus portucalensis
Synonyms
GSDMT, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
3 S-adenosyl-L-methionine + glycine = 3 S-adenosyl-L-homocysteine + betaine
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S-adenosyl-L-methionine + glycine = S-adenosyl-L-homocysteine + sarcosine
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S-adenosyl-L-methionine + N,N-dimethylglycine = S-adenosyl-L-homocysteine + betaine
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S-adenosyl-L-methionine + sarcosine = S-adenosyl-L-homocysteine + N,N-dimethylglycine
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PATHWAY SOURCE
PATHWAYS
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