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Information on EC 2.1.1.158 - 7-methylxanthosine synthase

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EC Tree
     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.158 7-methylxanthosine synthase
IUBMB Comments
The enzyme is specific for xanthosine, as XMP and xanthine cannot act as substrates [2,4]. The enzyme does not have N1- or N3- methylation activity . This is the first methylation step in the production of caffeine.
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
n-methyltransferase, xanthosine methyltransferase, cmxrs1, 7-n-methyltransferase, 7-methylxanthine synthase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
S-adenosyl-L-methionine + xanthosine = S-adenosyl-L-homocysteine + 7-methylxanthosine
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