Information on EC - precorrin-4 C11-methyltransferase

for references in articles please use BRENDA:EC2.1.1.133
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EC Tree
     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
       precorrin-4 C11-methyltransferase
IUBMB Comments
In the aerobic (late cobalt insertion) cobalamin biosythesis pathway, four enzymes are involved in the conversion of precorrin-3A to precorrin-6A. The first of the four steps is carried out by EC, precorrin-3B synthase (CobG), yielding precorrin-3B as the product. This is followed by three methylation reactions, which introduce a methyl group at C-17 (CobJ; EC, C-11 (CobM; EC and C-1 (CobF; EC of the macrocycle, giving rise to precorrin-4, precorrin-5, and precorrin-6A, respectively. See EC, cobalt-precorrin-4 methyltransferase, for the C11-methyltransferase enzyme that participates in the anaerobic cobalamin biosynthesis pathway.
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The expected taxonomic range for this enzyme is: Bacteria, Archaea
Cobalt-precorrin-4 methyltransferase, Methyltransferase (Pseudomonas denitrificans clone pXL151 gene cobF reduced), Methyltransferase, precorrin 2- (Pseudomonas denitrificans clone pXL151), Precorrin-3 methylase, Protein (Pseudomonas denitrificans clone pXL151 gene cobF reduced), S-Adenosyl-L-methionine-dependent cobalt-precorrin-4 transmethylase, more
S-adenosyl-L-methionine + precorrin-4 = S-adenosyl-L-homocysteine + precorrin-5
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