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Information on EC 2.1.1.118 - columbamine O-methyltransferase

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EC Tree
     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.118 columbamine O-methyltransferase
IUBMB Comments
The product of this reaction is a protoberberine alkaloid that is widely distributed in the plant kingdom. This enzyme is distinct in specificity from EC 2.1.1.88, 8-hydroxyquercetin 8-O-methyltransferase.
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The enzyme appears in viruses and cellular organisms
Synonyms
s-adenosyl-l-methionine:columbamine o-methyltransferase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
S-adenosyl-L-methionine + columbamine = S-adenosyl-L-homocysteine + palmatine
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