Information on EC 1.8.98.4 - coenzyme F420:CoB-CoM heterodisulfide,ferredoxin reductase

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The expected taxonomic range for this enzyme is: Methanosarcina acetivorans

EC NUMBER
COMMENTARY hide
1.8.98.4
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RECOMMENDED NAME
GeneOntology No.
coenzyme F420:CoB-CoM heterodisulfide,ferredoxin reductase
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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2 oxidized coenzyme F420 + 2 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + 2 H+ = 2 reduced coenzyme F420 + 2 oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB
show the reaction diagram
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
coenzyme B/coenzyme M regeneration III (coenzyme F420-dependent)
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Methane metabolism
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Metabolic pathways
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Microbial metabolism in diverse environments
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SYSTEMATIC NAME
IUBMB Comments
CoB,CoM,ferredoxin:coenzyme F420 oxidoreductase
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
oxidized coenzyme F420 + reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + H+
reduced coenzyme F420 + oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoBS
show the reaction diagram
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?
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
oxidized coenzyme F420 + reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + H+
reduced coenzyme F420 + oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoBS
show the reaction diagram
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?
COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
[4Fe-4S]-center
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METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SUBUNITS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
?
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x * 87000, subunit HdrA2, SDS-PAGE
Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
expressed in Escherichia coli BL21(DE3) cells
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