Disease on EC 1.8.98.2 - sulfiredoxin
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DISEASE 
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Adenocarcinoma
Nuclear Nrf2 expression is related to a poor survival in pancreatic adenocarcinoma.
Adenocarcinoma
Sulfiredoxin as a Potential Therapeutic Target for Advanced and Metastatic Prostate Cancer.
Brain Injuries
Sulfiredoxin-1 Attenuates Oxidative Stress via Nrf2/ARE Pathway and 2-Cys Prdxs After Oxygen-Glucose Deprivation in Astrocytes.
Brain Ischemia
Neuroprotective effects of sulfiredoxin-1 during cerebral ischemia/reperfusion oxidative stress injury in rats.
Brain Ischemia
Sulfiredoxin-1 exerts anti-apoptotic and neuroprotective effects against oxidative stress-induced injury in rat cortical astrocytes following exposure to oxygen-glucose deprivation and hydrogen peroxide.
Breast Neoplasms
Correction: Genetic Polymorphisms and Protein Expression of NRF2 and Sulfiredoxin Predict Survival Outcomes in Breast Cancer.
Breast Neoplasms
Genetic polymorphisms and protein expression of NRF2 and sulfiredoxin predict survival outcomes in breast cancer.
Breast Neoplasms
Maesopsin 4-O-beta-D-glucoside, a natural compound isolated from the leaves of Artocarpus tonkinensis, inhibits proliferation and up-regulates HMOX1, SRXN1 and BCAS3 in acute myeloid leukemia.
Carcinogenesis
Loss of sulfiredoxin renders mice resistant to azoxymethane/dextran sulfate sodium-induced colon carcinogenesis.
Carcinogenesis
Nrf2-activated expression of sulfiredoxin contributes to urethane-induced lung tumorigenesis.
Carcinogenesis
SRXN1 stimulates hepatocellular carcinoma tumorigenesis and metastasis through modulating ROS/p65/BTG2 signalling.
Carcinogenesis
Sulfiredoxin-Peroxiredoxin IV axis promotes human lung cancer progression through modulation of specific phosphokinase signaling.
Carcinogenesis
Tumor promoter-induced sulfiredoxin is required for mouse skin tumorigenesis.
Carcinoma
Nuclear factor erythroid-derived 2-like 2 (Nrf2) and DJ1 are prognostic factors in lung cancer.
Carcinoma
Sulfiredoxin may promote metastasis and invasion of cervical squamous cell carcinoma by epithelial-mesenchymal transition.
Carcinoma
[Highly expressed sulfiredoxin and ?-catenin are associated with malignancy of cervical squamous cell carcinoma].
Carcinoma, Hepatocellular
SRXN1 stimulates hepatocellular carcinoma tumorigenesis and metastasis through modulating ROS/p65/BTG2 signalling.
Carcinoma, Hepatocellular
Sulfiredoxin-1 is a promising novel prognostic biomarker for hepatocellular carcinoma.
Carcinoma, Squamous Cell
Sulfiredoxin may promote metastasis and invasion of cervical squamous cell carcinoma by epithelial-mesenchymal transition.
Carcinoma, Squamous Cell
[Highly expressed sulfiredoxin and ?-catenin are associated with malignancy of cervical squamous cell carcinoma].
Cerebral Infarction
Neuroprotective effects of sulfiredoxin-1 during cerebral ischemia/reperfusion oxidative stress injury in rats.
Cerebrovascular Disorders
Genetic Polymorphisms of Transcription Factor NRF2 and of its Host Gene Sulfiredoxin (SRXN1) are Associated with Cerebrovascular Disease in a Finnish Cohort, the TAMRISK Study.
Chronic Periodontitis
Comparative estimation of sulfiredoxin levels between chronic periodontitis and healthy patients - A case-control study.
Colorectal Neoplasms
Sulfiredoxin Promotes Colorectal Cancer Cell Invasion and Metastasis through a Novel Mechanism of Enhancing EGFR Signaling.
Diabetic Nephropathies
Sulfiredoxin-1 alleviates high glucose-induced podocyte injury though promoting Nrf2/ARE signaling via inactivation of GSK-3?.
Hypersensitivity
Role of sulfiredoxin as a peroxiredoxin-2 denitrosylase in human iPSC-derived dopaminergic neurons.
Hypertension
Genetic Polymorphisms of Transcription Factor NRF2 and of its Host Gene Sulfiredoxin (SRXN1) are Associated with Cerebrovascular Disease in a Finnish Cohort, the TAMRISK Study.
Idiopathic Pulmonary Fibrosis
Cell-specific elevation of NRF2 and sulfiredoxin-1 as markers of oxidative stress in the lungs of idiopathic pulmonary fibrosis and non-specific interstitial pneumonia.
Infarction, Middle Cerebral Artery
Neuroprotective effects of sulfiredoxin-1 during cerebral ischemia/reperfusion oxidative stress injury in rats.
Ischemic Stroke
Neuroprotective effects of sulfiredoxin-1 during cerebral ischemia/reperfusion oxidative stress injury in rats.
Leukemia, Myeloid, Acute
Maesopsin 4-O-beta-D-glucoside, a natural compound isolated from the leaves of Artocarpus tonkinensis, inhibits proliferation and up-regulates HMOX1, SRXN1 and BCAS3 in acute myeloid leukemia.
Lung Diseases, Interstitial
Cell-specific elevation of NRF2 and sulfiredoxin-1 as markers of oxidative stress in the lungs of idiopathic pulmonary fibrosis and non-specific interstitial pneumonia.
Lung Neoplasms
Nuclear factor E2-related factor 2 dependent overexpression of sulfiredoxin and peroxiredoxin III in human lung cancer.
Lung Neoplasms
Nuclear factor erythroid-derived 2-like 2 (Nrf2) and DJ1 are prognostic factors in lung cancer.
Lung Neoplasms
The redox regulator sulfiredoxin forms a complex with thioredoxin domain-containing 5 protein in response to ER stress in lung cancer cells.
Melanoma
Frugoside Induces Mitochondria-Mediated Apoptotic Cell Death through Inhibition of Sulfiredoxin Expression in Melanoma Cells.
Meningoencephalitis
Sulfiredoxin plays peroxiredoxin-dependent and -independent roles via the HOG signaling pathway in Cryptococcus neoformans and contributes to fungal virulence.
Myocardial Ischemia
Sulfiredoxin-1 enhances cardiac progenitor cell survival against oxidative stress via the upregulation of the ERK/NRF2 signal pathway.
Neoplasm Metastasis
SRXN1 stimulates hepatocellular carcinoma tumorigenesis and metastasis through modulating ROS/p65/BTG2 signalling.
Neoplasm Metastasis
Sulfiredoxin May Promote Cervical Cancer Metastasis via Wnt/?-Catenin Signaling Pathway.
Neoplasm Metastasis
Sulfiredoxin may promote metastasis and invasion of cervical squamous cell carcinoma by epithelial-mesenchymal transition.
Neoplasm Metastasis
Sulfiredoxin Promotes Colorectal Cancer Cell Invasion and Metastasis through a Novel Mechanism of Enhancing EGFR Signaling.
Neoplasms
Effective killing of cancer cells and regression of tumor growth by K27 targeting sulfiredoxin.
Neoplasms
Elucidation of the inhibition mechanism of sulfiredoxin using molecular modeling and development of its inhibitors.
Neoplasms
Identification and characterization of human leukocyte antigen class I ligands in renal cell carcinoma cells.
Neoplasms
Nuclear factor erythroid-derived 2-like 2 (Nrf2) and DJ1 are prognostic factors in lung cancer.
Neoplasms
SRXN1 stimulates hepatocellular carcinoma tumorigenesis and metastasis through modulating ROS/p65/BTG2 signalling.
Neoplasms
Sulfiredoxin as a Potential Therapeutic Target for Advanced and Metastatic Prostate Cancer.
Neoplasms
Sulfiredoxin inhibitor induces preferential death of cancer cells through reactive oxygen species-mediated mitochondrial damage.
Neoplasms
Sulfiredoxin is an AP-1 target gene that is required for transformation and shows elevated expression in human skin malignancies.
Neoplasms
Sulfiredoxin May Promote Cervical Cancer Metastasis via Wnt/?-Catenin Signaling Pathway.
Neoplasms
Sulfiredoxin may promote metastasis and invasion of cervical squamous cell carcinoma by epithelial-mesenchymal transition.
Neoplasms
Sulfiredoxin redox-sensitive interaction with S100A4 and non-muscle myosin IIA regulates cancer cell motility.
Neoplasms
Sulfiredoxin-Peroxiredoxin IV axis promotes human lung cancer progression through modulation of specific phosphokinase signaling.
Neoplasms
The cinnamon-derived Michael acceptor cinnamic aldehyde impairs melanoma cell proliferation, invasiveness, and tumor growth.
Neoplasms
Thioredoxin system-mediated regulation of mutant Kras associated pancreatic neoplasia and cancer.
Neoplasms
[Highly expressed sulfiredoxin and ?-catenin are associated with malignancy of cervical squamous cell carcinoma].
Neurodegenerative Diseases
Role of sulfiredoxin as a peroxiredoxin-2 denitrosylase in human iPSC-derived dopaminergic neurons.
Neurodegenerative Diseases
Sulfiredoxin-1 protects primary cultured astrocytes from ischemia-induced damage.
Pancreatic Neoplasms
Nuclear Nrf2 expression is related to a poor survival in pancreatic adenocarcinoma.
Pancreatitis
Sulfiredoxin-1 attenuates injury and inflammation in acute pancreatitis through the ROS/ER stress/Cathepsin B axis.
Periodontal Diseases
Comparative estimation of sulfiredoxin levels between chronic periodontitis and healthy patients - A case-control study.
Periodontitis
Comparative estimation of sulfiredoxin levels between chronic periodontitis and healthy patients - A case-control study.
Prostatic Intraepithelial Neoplasia
Sulfiredoxin as a Potential Therapeutic Target for Advanced and Metastatic Prostate Cancer.
Prostatic Neoplasms
Increased Peroxiredoxin 6 Expression Predicts Biochemical Recurrence in Prostate Cancer Patients After Radical Prostatectomy.
Prostatic Neoplasms
Sulfiredoxin as a Potential Therapeutic Target for Advanced and Metastatic Prostate Cancer.
Pulmonary Disease, Chronic Obstructive
The aryl hydrocarbon receptor suppresses cigarette-smoke-induced oxidative stress in association with dioxin response element (DRE)-independent regulation of sulfiredoxin 1.
Skin Neoplasms
Tumor promoter-induced sulfiredoxin is required for mouse skin tumorigenesis.
Stomach Neoplasms
Increased Sulfiredoxin Expression in Gastric Cancer Cells May Be a Molecular Target of the Anticancer Component Diallyl Trisulfide.
Uterine Cervical Neoplasms
Sulfiredoxin May Promote Cervical Cancer Metastasis via Wnt/?-Catenin Signaling Pathway.
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