show all | hide all No of entries

Information on EC 1.8.7.3 - ferredoxin:CoB-CoM heterodisulfide reductase

for references in articles please use BRENDA:EC1.8.7.3
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
IUBMB Comments
HdrABC is an enzyme complex that is found in most methanogens and catalyses the reduction of the CoB-CoM heterodisulfide back to CoB and CoM. HdrA contains a FAD cofactor that acts as the entry point for electrons, which are transferred via HdrC to the HdrB catalytic subunit. One form of the enzyme from Methanosarcina acetivorans (HdrA2B2C2) can also catalyse EC 1.8.98.4, coenzyme F420:CoB-CoM heterodisulfide,ferredoxin reductase. cf. EC 1.8.98.5, H2:CoB-CoM heterodisulfide,ferredoxin reductase, EC 1.8.98.6, formate:CoB-CoM heterodisulfide,ferredoxin reductase, and EC 1.8.98.1, dihydromethanophenazine:CoB-CoM heterodisulfide reductase.
Specify your search results
Select one or more organisms in this record: ?
The expected taxonomic range for this enzyme is: Bacteria, Archaea
Reaction Schemes
hide
2
oxidized ferredoxin [iron-sulfur] cluster
+
CoB
+
CoM
=
2
reduced ferredoxin [iron-sulfur] cluster
+
CoM-S-S-CoB
+
2
H+
2
oxidized ferredoxin [iron-sulfur] cluster
+
+
=
2
reduced ferredoxin [iron-sulfur] cluster
+
+
2
Synonyms
CoB-S-S-CoM reductase, Coenzyme B-Coenzyme M heterodisulfide reductase, hdrA1B1C1, hdrA2B2C2, HdrABC, HdrB, HdrB2, HdrB2C2, heterodisulfide reductase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2 oxidized ferredoxin [iron-sulfur] cluster + CoB + CoM = 2 reduced ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB + 2 H+
show the reaction diagram
-
-
-
-
Select items on the left to see more content.