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Disease on EC 1.8.4.12 - peptide-methionine (R)-S-oxide reductase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Acidosis
Anoxia, acidosis and intergenic interactions selectively regulate methionine sulfoxide reductase transcriptions in mouse embryonic stem cells.
Alzheimer Disease
Decrease in peptide methionine sulfoxide reductase in Alzheimer's disease brain.
Direct Interaction of Selenoprotein R with Clusterin and Its Possible Role in Alzheimer's Disease.
Methionine Sulfoxide Reductase-B3 (MsrB3) Protein Associates with Synaptic Vesicles and its Expression Changes in the Hippocampi of Alzheimer's Disease Patients.
Methionine Sulfoxide Reductase-B3 Risk Allele Implicated in Alzheimer's Disease Associates with Increased Odds for Brain Infarcts.
Mitochondrial methionine sulfoxide reductase B2 links oxidative stress to Alzheimer's disease-like pathology.
Oxidation of methionine 35 reduces toxicity of the amyloid beta-peptide(1-42) in neuroblastoma cells (IMR-32) via enzyme methionine sulfoxide reductase A expression and function.
Brain Diseases
Methionine sulfoxide reductase (Msr) dysfunction in human brain disease.
Brain Infarction
Methionine Sulfoxide Reductase-B3 Risk Allele Implicated in Alzheimer's Disease Associates with Increased Odds for Brain Infarcts.
Brain Injuries
Methionine Sulfoxide Reductase-B3 Risk Allele Implicated in Alzheimer's Disease Associates with Increased Odds for Brain Infarcts.
Breast Neoplasms
Important roles of multiple Sp1 binding sites and epigenetic modifications in the regulation of the methionine sulfoxide reductase B1 (MsrB1) promoter.
Carcinogenesis
Actin reduction by MsrB2 is a key component of the cytokinetic abscission checkpoint and prevents tetraploidy.
[Expression of methionine sulfoxide reductase in colorectal cancer stem cells in vitro].
Carcinoma
MSRB3 promotes the progression of clear cell renal cell carcinoma via regulating endoplasmic reticulum stress.
Carcinoma, Hepatocellular
Methionine Sulfoxide Reductase B1 Regulates Hepatocellular Carcinoma Cell Proliferation and Invasion via the Mitogen-Activated Protein Kinase Pathway and Epithelial-Mesenchymal Transition.
Carcinoma, Renal Cell
MSRB3 promotes the progression of clear cell renal cell carcinoma via regulating endoplasmic reticulum stress.
Cataract
Effect of blood-retinal barrier development on formation of selenite nuclear cataract in rat.
Effects of Sodium Selenite on Oxidative Damage in the Liver, Kidney and Brain in a Selenite Cataract Rat Model.
Involvement of MsrB1 in the regulation of redox balance and inhibition of peroxynitrite-induced apoptosis in human lens epithelial cells.
Citrullinemia
Metabolic studies in older mentally retarded patients: significance of metabolic testing and correlation with the clinical phenotype.
Colonic Neoplasms
MsrB3 deficiency induces cancer cell apoptosis through p53-independent and ER stress-dependent pathways.
Colorectal Neoplasms
[Expression of methionine sulfoxide reductase in colorectal cancer stem cells in vitro].
Craniosynostoses
Genome-wide association analysis uncovers variants for reproductive variation across dog breeds and links to domestication.
Deafness
Down-regulation of msrb3 and destruction of normal auditory system development through hair cell apoptosis in zebrafish.
Functional null mutations of MSRB3 encoding methionine sulfoxide reductase are associated with human deafness DFNB74.
Methionine sulfoxide reductase B3 deficiency causes hearing loss due to stereocilia degeneration and apoptotic cell death in cochlear hair cells.
Dehydration
Peptide-Bound Methionine Sulfoxide (MetO) Levels and MsrB2 Abundance Are Differentially Regulated during the Desiccation Phase in Contrasted Acer Seeds.
Dementia
Methionine Sulfoxide Reductase-B3 (MsrB3) Protein Associates with Synaptic Vesicles and its Expression Changes in the Hippocampi of Alzheimer's Disease Patients.
Methionine Sulfoxide Reductase-B3 Risk Allele Implicated in Alzheimer's Disease Associates with Increased Odds for Brain Infarcts.
Diabetes Mellitus
Metabolic studies in older mentally retarded patients: significance of metabolic testing and correlation with the clinical phenotype.
Mitochondrial MsrB2 serves as a switch and transducer for mitophagy.
Eye Diseases
Mitochondrial function and redox control in the aging eye: Role of MsrA and other repair systems in cataract and macular degenerations.
Hearing Loss
Functional null mutations of MSRB3 encoding methionine sulfoxide reductase are associated with human deafness DFNB74.
Methionine Sulfoxide Reductase A, B1 and B2 Are Likely to Be Involved in the Protection against Oxidative Stress in the Inner Ear.
Methionine sulfoxide reductase B3 deficiency causes hearing loss due to stereocilia degeneration and apoptotic cell death in cochlear hair cells.
Methionine Sulfoxide Reductase B3-Targeted In Utero Gene Therapy Rescues Hearing Function in a Mouse Model of Congenital Sensorineural Hearing Loss.
Hearing Loss, Sensorineural
Methionine Sulfoxide Reductase B3-Targeted In Utero Gene Therapy Rescues Hearing Function in a Mouse Model of Congenital Sensorineural Hearing Loss.
Infections
A Novel, Molybdenum-Containing Methionine Sulfoxide Reductase Supports Survival of Haemophilus influenzae in an In vivo Model of Infection.
A strain-specific catalase mutation and mutation of the metal-binding transporter gene mntC attenuate Neisseria gonorrhoeae in vivo but not by increasing susceptibility to oxidative killing by phagocytes.
Contribution of methionine sulfoxide reductase B (MsrB) to Francisella tularensis infection in mice.
NIa-pro of Papaya ringspot virus interacts with papaya methionine sulfoxide reductase B1.
Peptide Methionine Sulfoxide Reductase from Haemophilus influenzae Is Required for Protection against HOCl and Affects the Host Response to Infection.
Influenza, Human
Effects of selenium supplementation on selenoprotein gene expression and response to influenza vaccine challenge: a randomised controlled trial.
Insulin Resistance
Methionine sulfoxide reductase B1 deficiency does not increase high-fat diet-induced insulin resistance in mice.
Methionine sulfoxide reductase B3 deficiency inhibits the development of diet-induced insulin resistance in mice.
Leukemia
Overexpression of methionine sulfoxide reductases A and B2 protects MOLT-4 cells against zinc-induced oxidative stress.
Overexpression of mitochondrial methionine sulfoxide reductase B2 protects leukemia cells from oxidative stress-induced cell death and protein damage.
Lipoma
NFIB rearrangement in superficial, retroperitoneal, and colonic lipomas with aberrations involving chromosome band 9p22.
Lymphatic Metastasis
Increased expression of methionine sulfoxide reductases B3 is associated with poor prognosis in gastric cancer.
Myositis
The Protein Oxidation Repair Enzyme Methionine Sulfoxide Reductase A Modulates A? Aggregation and Toxicity In Vivo.
Myositis, Inclusion Body
The Protein Oxidation Repair Enzyme Methionine Sulfoxide Reductase A Modulates A? Aggregation and Toxicity In Vivo.
Neoplasm Metastasis
Identification of Key Gene and Pathways for the Prediction of Peritoneal Metastasis of Gastric Cancer by Co-expression Analysis.
Increased expression of methionine sulfoxide reductases B3 is associated with poor prognosis in gastric cancer.
Neoplasms
DNA methylation by dimethyl sulfoxide and methionine sulfoxide triggered by hydroxyl radical and implications for epigenetic modifications.
Down-regulation of MsrB3 induces cancer cell apoptosis through reactive oxygen species production and intrinsic mitochondrial pathway activation.
Genetic regulation of longevity and age-associated diseases through the methionine sulfoxide reductase system.
Increased expression of methionine sulfoxide reductases B3 is associated with poor prognosis in gastric cancer.
Methionine Sulfoxide Reductase B1 Regulates Hepatocellular Carcinoma Cell Proliferation and Invasion via the Mitogen-Activated Protein Kinase Pathway and Epithelial-Mesenchymal Transition.
Methionine sulfoxide reductase B1 regulates proliferation and invasion by affecting mitogen-activated protein kinase pathway and epithelial-mesenchymal transition in u2os cells.
MsrB3 deficiency induces cancer cell apoptosis through p53-independent and ER stress-dependent pathways.
MSRB3 promotes the progression of clear cell renal cell carcinoma via regulating endoplasmic reticulum stress.
Nervous System Diseases
Dopamine D2 receptor function is compromised in the brain of the methionine sulfoxide reductase A knockout mouse.
Neurodegenerative Diseases
Age-associated neurodegeneration and oxidative damage to lipids, proteins and DNA.
Genetic regulation of longevity and age-associated diseases through the methionine sulfoxide reductase system.
Obesity
12q14 microduplication: a new clinical entity reciprocal to the microdeletion syndrome?
Obesity reduces methionine sulphoxide reductase activity in visceral adipose tissue.
Parkinson Disease
Mitochondrial MsrB2 serves as a switch and transducer for mitophagy.
peptide-methionine (r)-s-oxide reductase deficiency
Down-regulation of MsrB3 induces cancer cell apoptosis through reactive oxygen species production and intrinsic mitochondrial pathway activation.
In Vivo Effects of Methionine Sulfoxide Reductase Deficiency in Drosophila melanogaster.
Metabolic studies in older mentally retarded patients: significance of metabolic testing and correlation with the clinical phenotype.
Methionine Sulfoxide Reductase A, B1 and B2 Are Likely to Be Involved in the Protection against Oxidative Stress in the Inner Ear.
Methionine sulfoxide reductase B1 deficiency does not increase high-fat diet-induced insulin resistance in mice.
Methionine sulfoxide reductase B3 deficiency causes hearing loss due to stereocilia degeneration and apoptotic cell death in cochlear hair cells.
Methionine sulfoxide reductase B3 deficiency inhibits cell growth through the activation of p53-p21 and p27 pathways.
Methionine sulfoxide reductase B3 deficiency inhibits the development of diet-induced insulin resistance in mice.
Methionine sulfoxide reductase B3 deficiency stimulates heme oxygenase-1 expression via ROS-dependent and Nrf2 activation pathways.
Methionine Sulfoxide Reductase B3-Targeted In Utero Gene Therapy Rescues Hearing Function in a Mouse Model of Congenital Sensorineural Hearing Loss.
MsrB1 (methionine-R-sulfoxide reductase 1) knock-out mice: roles of MsrB1 in redox regulation and identification of a novel selenoprotein form.
MsrB3 deficiency induces cancer cell apoptosis through p53-independent and ER stress-dependent pathways.
Reaction mechanism, evolutionary analysis, and role of zinc in Drosophila methionine-R-sulfoxide reductase.
Selenoprotein MsrB1 deficiency exacerbates acetaminophen-induced hepatotoxicity via increased oxidative damage.
Starvation
Analyses of fruit flies that do not express selenoproteins or express the mouse selenoprotein, methionine sulfoxide reductase b1, reveal a role of selenoproteins in stress resistance.
Stillbirth
Genome-wide association analysis uncovers variants for reproductive variation across dog breeds and links to domestication.
Stomach Neoplasms
Identification of Key Gene and Pathways for the Prediction of Peritoneal Metastasis of Gastric Cancer by Co-expression Analysis.
Stroke
Methionine Sulfoxide Reductase-B3 Risk Allele Implicated in Alzheimer's Disease Associates with Increased Odds for Brain Infarcts.
Tuberculosis
Peptide methionine sulfoxide reductase from Escherichia coli and Mycobacterium tuberculosis protects bacteria against oxidative damage from reactive nitrogen intermediates.
Tularemia
Contribution of methionine sulfoxide reductase B (MsrB) to Francisella tularensis infection in mice.
Uterine Cervical Neoplasms
A three-gene novel predictor for improving the prognosis of cervical cancer.