Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

Reference on EC 1.8.4.12 - peptide-methionine (R)-S-oxide reductase

Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Grimaud, R.; Ezraty, B.; Mitchell, J.K.; Lafitte, D.; Briand, C.; Derrick, P.J.; Barras, F.
Repair of oxidized proteins: identification of a new methionine sulfoxide reductase
J. Biol. Chem.
276
48915-48920
2001
Escherichia coli
Manually annotated by BRENDA team
Kryukov, G.V.; Kumar, R.A.; Koc, A.; Sun, Z.; Gladyshev, V.N.
Selenoprotein R is a zinc-containing stereo-specific methionine sulfoxide reductase
Proc. Natl. Acad. Sci. USA
99
4245-4250
2002
Mus musculus, Drosophila melanogaster (Q8INK9)
Manually annotated by BRENDA team
Moskovitz, J.; Poston, J.M.; Berlett, B.S.; Nosworthy, N.J.; Szczepanowski, R.; Stadtman, E.R.
Identification and characterization of a putative active site for peptide methionine sulfoxide reductase (MsrA) and its substrate stereospecificity
J. Biol. Chem.
275
14167-14172
2000
Homo sapiens
Manually annotated by BRENDA team
Olry, A.; Boschi-Muller, S.; Marraud, M.; Sanglier-Cianferani, S.; Van Dorsselear, A.; Branlant, G.
Characterization of the methionine sulfoxide reductase activities of PILB, a probable virulence factor from Neisseria meningitidis
J. Biol. Chem.
277
12016-12022
2002
Neisseria meningitidis
Manually annotated by BRENDA team
Kauffmann, B.; Favier, F.; Olry, A.; Boschi-Muller, S.; Carpentier, P.; Branlant, G.; Aubry, A.
Crystallization and preliminary X-ray diffraction studies of the peptide methionine sulfoxide reductase B domain of Neisseria meningitidis PILB
Acta Crystallogr. Sect. D
58
1467-1469
2002
Neisseria meningitidis
Manually annotated by BRENDA team
Walter, J.; Chagnaud, P.; Tannock, G.W.; Loach, D.M.; Dal Bello, F.; Jenkinson, H.F.; Hammes, W.P.; Hertel, C.
A high-molecular-mass surface protein (Lsp) and methionine sulfoxide reductase B (MsrB) contribute to the ecological performance of Lactobacillus reuteri in the murine gut
Appl. Environ. Microbiol.
71
979-986
2005
Limosilactobacillus reuteri, Limosilactobacillus reuteri 100-23
Manually annotated by BRENDA team
Weissbach, H.; Etienne, F.; Hoshi, T.; Heinemann, S.H.; Lowther, W.T.; Matthews, B.; St John, G.; Nathan, C.; Brot, N.
Peptide methionine sulfoxide reductase: structure, mechanism of action, and biological function
Arch. Biochem. Biophys.
397
172-178
2002
Escherichia coli
Manually annotated by BRENDA team
Moskovitz, J.; Singh, V.K.; Requena, J.; Wilkinson, B.J.; Jayaswal, R.K.; Stadtman, E.R.
Purification and characterization of methionine sulfoxide reductases from mouse and Staphylococcus aureus and their substrate stereospecificity
Biochem. Biophys. Res. Commun.
290
62-65
2002
Staphylococcus aureus, Mus musculus
Manually annotated by BRENDA team
Bar-Noy, S.; Moskovitz, J.
Mouse methionine sulfoxide reductase B: effect of selenocysteine incorporation on its activity and expression of the seleno-containing enzyme in bacterial and mammalian cells
Biochem. Biophys. Res. Commun.
297
956-961
2002
Mus musculus
Manually annotated by BRENDA team
Spector, D.; Etienne, F.; Brot, N.; Weissbach, H.
New membrane-associated and soluble peptide methionine sulfoxide reductases in Escherichia coli
Biochem. Biophys. Res. Commun.
302
284-289
2003
Escherichia coli
Manually annotated by BRENDA team
Etienne, F.; Resnick, L.; Sagher, D.; Brot, N.; Weissbach, H.
Reduction of Sulindac to its active metabolite, sulindac sulfide: assay and role of the methionine sulfoxide reductase system
Biochem. Biophys. Res. Commun.
312
1005-1010
2003
Bos taurus, Escherichia coli
Manually annotated by BRENDA team
Olry, A.; Boschi-Muller, S.; Branlant, G.
Kinetic characterization of the catalytic mechanism of methionine sulfoxide reductase B from Neisseria meningitidis
Biochemistry
43
11616-11622
2004
Neisseria meningitidis
Manually annotated by BRENDA team
Weissbach, H.; Resnick, L.; Brot, N.
Methionine sulfoxide reductases: history and cellular role in protecting against oxidative damage
Biochim. Biophys. Acta
1703
203-212
2005
Bos taurus, Saccharomyces cerevisiae, Streptococcus pneumoniae, Escherichia coli, Haemophilus influenzae, Helicobacter pylori, Homo sapiens, Mus musculus, Neisseria gonorrhoeae, Neisseria meningitidis, Streptococcus gordonii, Streptococcus gordonii (Q9LAM9)
Manually annotated by BRENDA team
Moskovitz, J.
Methionine sulfoxide reductases: ubiquitous enzymes involved in antioxidant defense, protein regulation, and prevention of aging-associated diseases
Biochim. Biophys. Acta
1703
213-219
2005
Arabidopsis thaliana, Saccharomyces cerevisiae, Escherichia coli, Homo sapiens, Staphylococcus aureus, Mus musculus, Sus scrofa
Manually annotated by BRENDA team
Ezraty, B.; Aussel, L.; Barras, F.
Methionine sulfoxide reductases in prokaryotes
Biochim. Biophys. Acta
1703
221-229
2005
Aggregatibacter actinomycetemcomitans, Bacillus subtilis, Escherichia coli, Dickeya chrysanthemi, Helicobacter pylori, Staphylococcus aureus, Mycobacterium tuberculosis, Mycolicibacterium smegmatis, Neisseria gonorrhoeae, Neisseria meningitidis, no activity in Aquifex aeolicus, Sinorhizobium meliloti, no activity in Thermotoga maritima, Vibrio cholerae serotype O1
Manually annotated by BRENDA team
Boschi-Muller, S.; Olry, A.; Antoine, M.; Branlant, G.
The enzymology and biochemistry of methionine sulfoxide reductases
Biochim. Biophys. Acta
1703
231-238
2005
Bacillus subtilis, Escherichia coli, Neisseria meningitidis, Xanthomonas campestris
Manually annotated by BRENDA team
Kauffmann, B.; Aubry, A.; Favier, F.
The three-dimensional structures of peptide methionine sulfoxide reductases: current knowledge and open questions
Biochim. Biophys. Acta
1703
249-260
2005
Caulobacter vibrioides, Drosophila melanogaster, Escherichia coli, Neisseria meningitidis, Pseudomonas aeruginosa, Synechococcus elongatus, Neisseria gonorrhoeae (P14930)
Manually annotated by BRENDA team
Petropoulos, I.; Friguet, B.
Protein maintenance in aging and replicative senescence: a role for the peptide methionine sulfoxide reductases
Biochim. Biophys. Acta
1703
261-266
2005
Drosophila melanogaster, Escherichia coli, Homo sapiens, Rattus norvegicus, Saccharomyces cerevisiae
Manually annotated by BRENDA team
Jung, S.; Hansel, A.; Kasperczyk, H.; Hoshi, T.; Heinemann, S.H.
Activity, tissue distribution and site-directed mutagenesis of a human peptide methionine sulfoxide reductase of type B: hCBS1
FEBS Lett.
527
91-94
2002
Homo sapiens
Manually annotated by BRENDA team
Picot, C.R.; Perichon, M.; Cintrat, J.C.; Friguet, B.; Petropoulos, I.
The peptide methionine sulfoxide reductases, MsrA and MsrB (hCBS-1), are downregulated during replicative senescence of human WI-38 fibroblasts
FEBS Lett.
558
74-78
2004
Homo sapiens
Manually annotated by BRENDA team
Vougier, S.; Mary, J.; Dautin, N.; Vinh, J.; Friguet, B.; Ladant, D.
Essential role of methionine residues in calmodulin binding to Bordetelle pertussis adenylate cyclase, as probed by selective oxidation and repair by the peptide methionine sulfoxide reductases
J. Biol. Chem.
279
30210-30218
2004
Homo sapiens
Manually annotated by BRENDA team
Singh, V.K.; Moskovitz, J.
Multiple methionine sulfoxide reductase genes in Staphylococcus aureus: expression of activity and roles in tolerance of oxidative stress
Microbiology
149
2739-2747
2003
Staphylococcus aureus
Manually annotated by BRENDA team
Stadtman, E.R.; Moskovitz, J.; Berlett, B.S.; Levine, R.L.
Cyclic axidation and reduction of protein methionine residues is an important antioxidant mechanism
Mol. Cell. Biochem.
2347235
3-9
2002
Mus musculus
-
Manually annotated by BRENDA team
Alamuri, P.; Maier, R.J.
Methionine sulphoxide reductase is an important antioxidant enzyme in the gastric pathogen Helicobacter pylori
Mol. Microbiol.
53
1397-1406
2004
Helicobacter pylori
Manually annotated by BRENDA team
Lowther, W.T.; Weissbach, H.; Etienne, F.; Brot, N.; Matthews, B.W.
The mirrored methionine sulfoxide reductases of Neisseria gonorrhoeae pilB
Nat. Struct. Biol.
9
348-352
2002
Escherichia coli (P0A746), Neisseria gonorrhoeae (P14930), Neisseria gonorrhoeae, Homo sapiens (Q9Y3D2)
Manually annotated by BRENDA team
Gustavsson, N.; Kokke, B.P.; Harndahl, U.; Silow, M.; Bechtold, U.; Poghosyan, Z.; Murphy, D.; Boelens, W.C.; Sundby, C.
A peptide methionine sulfoxide reductase highly expressed in photosynthetic tissue in Arabidopsis thaliana can protect the chaperone-like activity of a chloroplast-localized small heat shock protein
Plant J.
29
545-553
2002
Arabidopsis thaliana
Manually annotated by BRENDA team
In, O.; Berberich, T.; Romdhane, S.; Feierabend, J.
Changes in gene expression during dehardening of cold-hardened winter rye (Secale cereale L.) leaves and potential role of a peptide methionine sulfoxide reductase in cold-acclimation
Planta
220
941-950
2005
Secale cereale
Manually annotated by BRENDA team
Koc, A.; Gasch, A.P.; Rutherford, J.C.; Kim, H.Y.; Gladyshev, V.N.
Methionine sulfoxide reductase regulation of yeast lifespan reveals reactive oxygen species-dependent and -independent components of aging
Proc. Natl. Acad. Sci. USA
101
7999-8004
2004
Saccharomyces cerevisiae, Saccharomyces cerevisiae BY4741
Manually annotated by BRENDA team
Kim, H.Y.; Gladyshev, V.N.
Characterization of mouse endoplasmic reticulum methionine-R-sulfoxide reductase
Biochem. Biophys. Res. Commun.
320
1277-1283
2004
Mus musculus (Q8BU85), Mus musculus
Manually annotated by BRENDA team
Schallreuter, K.U.; Rubsam, K.; Chavan, B.; Zothner, C.; Gillbro, J.M.; Spencer, J.D.; Wood, J.M.
Functioning methionine sulfoxide reductases A and B are present in human epidermal melanocytes in the cytosol and in the nucleus
Biochem. Biophys. Res. Commun.
342
145-152
2006
Homo sapiens
Manually annotated by BRENDA team
Moskovitz, J.
Roles of methionine suldfoxide reductases in antioxidant defense, protein regulation and survival
Curr. Pharm. Des.
11
1451-1457
2005
Arabidopsis thaliana, Saccharomyces cerevisiae, Homo sapiens, Mus musculus
Manually annotated by BRENDA team
Marchetti Maria, A.; Pizarro Gresin, O.; Sagher, D.; Deamicis, C.; Brot, N.; Hejtmancik, J.F.; Weissbach, H.; Kantorow, M.
Methionine sulfoxide reductases B1, B2, and B3 are present in the human lens and confer oxidative stress resistance to lens cells
Invest. Ophthalmol. Vis. Sci.
46
2107-2112
2005
Homo sapiens
Manually annotated by BRENDA team
Brot, N.; Collet, J.F.; Johnson, L.C.; Jonsson, T.J.; Weissbach, H.; Lowther, W.T.
The thioredoxin domain of Neisseria gonorrhoeae PilB can use electrons from DsbD to reduce downstream methionine sulfoxide reductases
J. Biol. Chem.
281
32668-32675
2006
Neisseria gonorrhoeae
Manually annotated by BRENDA team
Vieira Dos Santos, C.; Cuine, S.; Rouhier, N.; Rey, P.
The Arabidopsis plastidic methionine sulfoxide reductase B proteins. Sequence and activity characteristics, comparison of the expression with plastidic methionine sulfoxide reductase A, and induction by photooxidative stress
Plant Physiol.
138
909-922
2005
Arabidopsis thaliana
Manually annotated by BRENDA team
Kim, H.Y.; Gladyshev, V.N.
Different catalytic mechanisms in mammalian selenocysteine- and cysteine-containing methionine-R-sulfoxide reductases
PLoS Biol.
3
2080-2089
2005
Homo sapiens, Mus musculus
-
Manually annotated by BRENDA team
Sagher, D.; Brunell, D.; Hejtmancik, J.F.; Kantorow, M.; Brot, N.; Weissbach, H.
Thionein can serve as a reducing agent for the methionine sulfoxide reductases
Proc. Natl. Acad. Sci. USA
103
8656-8661
2006
Escherichia coli, Homo sapiens
Manually annotated by BRENDA team
Skaar, E.P.; Tobiason, D.M.; Quick, J.; Judd, R.C.; Weissbach, H.; Etienne, F.; Brot, N.; Seifert, H.S.
The outer membrane localization of the Neisseria gonorrhoeae MsrA/B is involved in survival against reactive oxygen species
Proc. Natl. Acad. Sci. USA
99
10108-10113
2002
Neisseria gonorrhoeae, Neisseria gonorrhoeae MS11
Manually annotated by BRENDA team
Olry, A.; Boschi-Muller, S.; Yu, H.; Burnel, D.; Branlant, G.
Insights into the role of the metal binding site in methionine-R-sulfoxide reductases B
Protein Sci.
14
2828-2837
2005
Escherichia coli, Neisseria meningitidis
Manually annotated by BRENDA team
Cabreiro, F.; Picot, C.R.; Perichon, M.; Friguet, B.; Petropoulos, I.
Overexpression of methionine sulfoxide reductases A and B2 protects MOLT-4 cells against zinc-induced oxidative stress
Antioxid. Redox Signal.
11
215-225
2009
Homo sapiens (Q9Y3D2)
Manually annotated by BRENDA team
Boschi-Muller, S.; Gand, A.; Branlant, G.
The methionine sulfoxide reductases: Catalysis and substrate specificities
Arch. Biochem. Biophys.
474
266-273
2008
Neisseria meningitidis (Q9JWM8)
Manually annotated by BRENDA team
Lee, T.H.; Kim, H.Y.
An anaerobic bacterial MsrB model reveals catalytic mechanisms, advantages, and disadvantages provided by selenocysteine and cysteine in reduction of methionine-R-sulfoxide
Arch. Biochem. Biophys.
478
175-180
2008
Clostridium sp.
Manually annotated by BRENDA team
Ding, D.; Sagher, D.; Laugier, E.; Rey, P.; Weissbach, H.; Zhang, X.H.
Studies on the reducing systems for plant and animal thioredoxin-independent methionine sulfoxide reductases B
Biochem. Biophys. Res. Commun.
361
629-633
2007
Nicotiana tabacum (A7U629), Nicotiana tabacum
Manually annotated by BRENDA team
Kim, H.Y.; Kim, J.R.
Thioredoxin as a reducing agent for mammalian methionine sulfoxide reductases B lacking resolving cysteine
Biochem. Biophys. Res. Commun.
371
490-494
2008
Mus musculus (Q78J03), Homo sapiens (Q8IXL7)
Manually annotated by BRENDA team
Kim, H.Y.; Gladyshev, V.N.
Methionine sulfoxide reductases: selenoprotein forms and roles in antioxidant protein repair in mammals
Biochem. J.
407
321-329
2007
Drosophila melanogaster, Neisseria meningitidis, Bacillus subtilis (P54155), Mus musculus (Q8BU85), Homo sapiens (Q8IXL7)
Manually annotated by BRENDA team
Chen, B.; Markillie, L.M.; Xiong, Y.; Mayer, M.U.; Squier, T.C.
Increased catalytic efficiency following gene fusion of bifunctional methionine sulfoxide reductase enzymes from Shewanella oneidensis
Biochemistry
46
14153-14161
2007
Shewanella oneidensis
Manually annotated by BRENDA team
Le, D.T.; Liang, X.; Fomenko, D.E.; Raza, A.S.; Chong, C.K.; Carlson, B.A.; Hatfield, D.L.; Gladyshev, V.N.
Analysis of methionine/selenomethionine oxidation and methionine sulfoxide reductase function using methionine-rich proteins and antibodies against their oxidized forms
Biochemistry
47
6685-6694
2008
Mus musculus (Q78J03)
Manually annotated by BRENDA team
Quinternet, M.; Tsan, P.; Neiers, F.; Beaufils, C.; Boschi-Muller, S.; Averlant-Petit, M.C.; Branlant, G.; Cung, M.T.
Solution structure and dynamics of the reduced and oxidized forms of the N-terminal domain of PilB from Neisseria meningitidis
Biochemistry
47
8577-8589
2008
Neisseria meningitidis
Manually annotated by BRENDA team
Zhang, X.H.; Weissbach, H.
Origin and evolution of the protein-repairing enzymes methionine sulphoxide reductases
Biol. Rev. Camb. Philos. Soc.
83
249-257
2008
Haloarcula marismortui, Halobacterium salinarum, Halobacterium salinarum NRC 1, Methanococcoides burtonii, Methanosarcina acetivorans, Methanosarcina barkeri, Methanosarcina barkeri Fusaro / DSM 804, Methanosarcina mazei, Methanothermobacter thermautotrophicus (O26807), Natronomonas pharaonis, no activity in Aeropyrum pernix K1, no activity in Archaeoglobus fulgidus DSM 4304, no activity in Bifidobacterium longum, no activity in Bifidobacterium longum NCC2705, no activity in Clostridium tetani, no activity in Clostridium tetani E88, no activity in Ferroplasma acidarmanus, no activity in Methanocaldococcus jannaschii, no activity in Methanococcus maripaludis, no activity in Methanococcus maripaludis S2, no activity in Methanopyrus kandleri, no activity in Methanopyrus kandleri AV19, no activity in Nanoarchaeum equitans, no activity in Nanoarchaeum equitans Kin4-M, no activity in Picrophilus torridus, no activity in Pyrobaculum aerophilum, no activity in Pyrobaculum aerophilum IM2, no activity in Pyrococcus abyssi, no activity in Pyrococcus abyssi GE5, no activity in Pyrococcus furiosus, no activity in Pyrococcus horikoshii, no activity in Pyrococcus horikoshii OT3, no activity in Sulfolobus acidocaldarius, no activity in Sulfolobus solfataricus, no activity in Sulfolobus solfataricus P2, no activity in Sulfolobus tokodaii, no activity in Sulfolobus tokodaii 7, no activity in Thermococcus kodakarensis, no activity in Thermococcus kodakarensis KOD1, no activity in Thermoplasma acidophilum, no activity in Thermoplasma volcanium, no activity in Thermoplasma volcanium GSS1
Manually annotated by BRENDA team
Uthus, E.O.; Moskovitz, J.
Specific activity of methionine sulfoxide reductase in CD-1 mice is significantly affected by dietary selenium but not zinc
Biol. Trace Elem. Res.
115
265-276
2007
Mus musculus
Manually annotated by BRENDA team
You, C.; Sekowska, A.; Francetic, O.; Martin-Verstraete, I.; Wang, Y.; Danchin, A.
Spx mediates oxidative stress regulation of the methionine sulfoxide reductases operon in Bacillus subtilis
BMC Microbiol.
8
128
2008
Bacillus subtilis
Manually annotated by BRENDA team
De Luca, A.; Sacchetta, P.; Nieddu, M.; Di Ilio, C.; Favaloro, B.
Important roles of multiple Sp1 binding sites and epigenetic modifications in the regulation of the methionine sulfoxide reductase B1 (MsrB1) promoter
BMC Mol. Biol.
8
39
2007
Homo sapiens (Q9NZV6), Homo sapiens
Manually annotated by BRENDA team
Picot, C.R.; Moreau, M.; Juan, M.; Noblesse, E.; Nizard, C.; Petropoulos, I.; Friguet, B.
Impairment of methionine sulfoxide reductase during UV irradiation and photoaging
Exp. Gerontol.
42
859-863
2007
Homo sapiens (Q8IXL7), Homo sapiens (Q9Y3D2), Homo sapiens
Manually annotated by BRENDA team
Vieira Dos Santos, C.; Laugier, E.; Tarrago, L.; Massot, V.; Issakidis-Bourguet, E.; Rouhier, N.; Rey, P.
Specificity of thioredoxins and glutaredoxins as electron donors to two distinct classes of Arabidopsis plastidial methionine sulfoxide reductases B
FEBS Lett.
581
4371-4376
2007
Arabidopsis sp.
Manually annotated by BRENDA team
Fukushima, E.; Shinka, Y.; Fukui, T.; Atomi, H.; Imanaka, T.
Methionine sulfoxide reductase from the hyperthermophilic archaeon Thermococcus kodakaraensis, an enzyme designed to function at suboptimal growth temperatures
J. Bacteriol.
189
7134-7144
2007
Thermococcus kodakarensis
Manually annotated by BRENDA team
Neiers, F.; Sonkaria, S.; Olry, A.; Boschi-Muller, S.; Branlant, G.
Characterization of the amino acids from Neisseria meningitidis methionine sulfoxide reductase B involved in the chemical catalysis and substrate specificity of the reductase step
J. Biol. Chem.
282
32397-32405
2007
Neisseria meningitidis
Manually annotated by BRENDA team
Cabreiro, F.; Picot, C.R.; Perichon, M.; Castel, J.; Friguet, B.; Petropoulos, I.
Overexpression of mitochondrial methionine sulfoxide reductase B2 protects leukemia cells from oxidative stress-induced cell death and protein damage
J. Biol. Chem.
283
16673-16681
2008
Homo sapiens (Q9Y3D2)
Manually annotated by BRENDA team
Schallreuter, K.U.; Ruebsam, K.; Gibbons, N.C.; Maitland, D.J.; Chavan, B.; Zothner, C.; Rokos, H.; Wood, J.M.
Methionine sulfoxide reductases A and B are deactivated by hydrogen peroxide (H2O2) in the epidermis of patients with vitiligo
J. Invest. Dermatol.
128
808-815
2008
Homo sapiens (Q9NZV6), Homo sapiens
Manually annotated by BRENDA team
Park, A.K.; Shin, Y.J.; Moon, J.H.; Kim, Y.K.; Hwang, K.Y.; Chi, Y.M.
Overexpression, purification, and preliminary X-ray crystallographic studies of methionine sulfoxide reductase B from Bacillus subtilis
J. Microbiol. Biotechnol.
18
59-62
2008
Bacillus subtilis
Manually annotated by BRENDA team
Atack, J.M.; Kelly, D.J.
Contribution of the stereospecific methionine sulphoxide reductases MsrA and MsrB to oxidative and nitrosative stress resistance in the food-borne pathogen Campylobacter jejuni
Microbiology
154
2219-2230
2008
Campylobacter jejuni, Campylobacter jejuni NCTC 11168
Manually annotated by BRENDA team
Kwon, S.J.; Kwon, S.I.; Bae, M.S.; Cho, E.J.; Park, O.K.
Role of the methionine sulfoxide reductase MsrB3 in cold acclimation in Arabidopsis
Plant Cell Physiol.
48
1713-1723
2007
Arabidopsis thaliana
Manually annotated by BRENDA team
Breivik, A.S.; Aachmann, F.L.; Sal, L.S.; Kim, H.Y.; Del Conte, R.; del Conte, R.; Gladyshev, V.N.; Dikiy, A.
1H, 15N and 13C NMR assignments of mouse methionine sulfoxide reductase B2
Biomol. NMR Assign.
2
199-201
2008
Mus musculus (Q78J03), Mus musculus
Manually annotated by BRENDA team
Soriani, F.M.; Kress, M.R.; Fagundes de Gouvea, P.; Malavazi, I.; Savoldi, M.; Gallmetzer, A.; Strauss, J.; Goldman, M.H.; Goldman, G.H.
Functional characterization of the Aspergillus nidulans methionine sulfoxide reductases (msrA and msrB)
Fungal Genet. Biol.
46
410-417
2009
Aspergillus nidulans
Manually annotated by BRENDA team
Tarrago, L.; Laugier, E.; Zaffagnini, M.; Marchand, C.; Le Marechal, P.; Rouhier, N.; Lemaire, S.D.; Rey, P.
Regeneration mechanisms of Arabidopsis thaliana methionine sulfoxide reductases B by glutaredoxins and thioredoxins
J. Biol. Chem.
284
18963-18971
2009
Arabidopsis thaliana
Manually annotated by BRENDA team
Ranaivoson, F.M.; Neiers, F.; Kauffmann, B.; Boschi-Muller, S.; Branlant, G.; Favier, F.
Methionine sulfoxide reductase B displays a high level of flexibility
J. Mol. Biol.
394
83-93
2009
Xanthomonas campestris (Q8P4Q6), Xanthomonas campestris, Neisseria meningitidis (Q9JWM8), Neisseria meningitidis
Manually annotated by BRENDA team
Laugier, E.; Tarrago, L.; Santos, C.V.; Eymery, F.; Havaux, M.; Rey, P.
Arabidopsis thaliana plastidial methionine sulfoxide reductases B, MSRBs, account for most leaf peptide MSR activity and are essential for growth under environmental constraints through a role in the preservation of photosystem antennae
Plant J.
61
271-282
2010
Arabidopsis thaliana
Manually annotated by BRENDA team
Uthus, E.O.
Determination of the specific activities of methionine sulfoxide reductase A and B by capillary electrophoresis
Anal. Biochem.
401
68-73
2010
Mus musculus
Manually annotated by BRENDA team
Binger, K.J.; Griffin, M.D.; Heinemann, S.H.; Howlett, G.J.
Methionine-oxidized amyloid fibrils are poor substrates for human methionine sulfoxide reductases A and B2
Biochemistry
49
2981-2983
2010
Homo sapiens
Manually annotated by BRENDA team
Pascual, I.; Larrayoz, I.M.; Campos, M.M.; Rodriguez, I.R.
Methionine sulfoxide reductase B2 is highly expressed in the retina and protects retinal pigmented epithelium cells from oxidative damage
Exp. Eye Res.
90
420-428
2010
Homo sapiens, Macaca mulatta
Manually annotated by BRENDA team
Zhao, C.; Hartke, A.; La Sorda, M.; Posteraro, B.; Laplace, J.M.; Auffray, Y.; Sanguinetti, M.
Role of methionine sulfoxide reductases A and B of Enterococcus faecalis in oxidative stress and virulence
Infect. Immun.
78
3889-3897
2010
Enterococcus faecalis, Enterococcus faecalis JH2-2
Manually annotated by BRENDA team
Tarrago, L.; Laugier, E.; Zaffagnini, M.; Marchand, C.H.; Le Marechal, P.; Lemaire, S.D.; Rey, P.
Plant thioredoxin CDSP32 regenerates 1-Cys methionine sulfoxide reductase B activity through the direct reduction of sulfenic acid
J. Biol. Chem.
285
14964-14972
2010
Arabidopsis thaliana
Manually annotated by BRENDA team
Cao, G.; Lee, K.P.; van der Wijst, J.; de Graaf, M.; van der Kemp, A.; Bindels, R.J.; Hoenderop, J.G.
Methionine sulfoxide reductase B1 (MsrB1) recovers TRPM6 channel activity during oxidative stress
J. Biol. Chem.
285
26081-26087
2010
Mus musculus
Manually annotated by BRENDA team
Aachmann, F.L.; Sal, L.S.; Kim, H.Y.; Marino, S.M.; Gladyshev, V.N.; Dikiy, A.
Insights into function, catalytic mechanism, and fold evolution of selenoprotein methionine sulfoxide reductase B1 through structural analysis
J. Biol. Chem.
285
33315-33323
2010
Mus musculus (Q9JLC3)
Manually annotated by BRENDA team
Oh, S.K.; Baek, K.H.; Seong, E.S.; Joung, Y.H.; Choi, G.J.; Park, J.M.; Cho, H.S.; Kim, E.A.; Lee, S.; Choi, D.
CaMsrB2, pepper methionine sulfoxide reductase B2, is a novel defense regulator against oxidative stress and pathogen attack
Plant Physiol.
154
245-261
2010
Capsicum annuum (B7S5L1)
Manually annotated by BRENDA team
Liang, X.; Fomenko, D.E.; Hua, D.; Kaya, A.; Gladyshev, V.N.
Diversity of protein and mRNA forms of mammalian methionine sulfoxide reductase B1 due to intronization and protein processing
PLoS ONE
5
e11497
2010
Mus musculus
Manually annotated by BRENDA team
Dhandayuthapani, S.; Jagannath, C.; Nino, C.; Saikolappan, S.; Sasindran, S.J.
Methionine sulfoxide reductase B (MsrB) of Mycobacterium smegmatis plays a limited role in resisting oxidative stress
Tuberculosis
89
S26-S32
2009
Mycolicibacterium smegmatis
Manually annotated by BRENDA team
Lim, D.H.; Han, J.Y.; Kim, J.R.; Lee, Y.S.; Kim, H.Y.
Methionine sulfoxide reductase B in the endoplasmic reticulum is critical for stress resistance and aging in Drosophila
Biochem. Biophys. Res. Commun.
419
20-26
2012
Homo sapiens
Manually annotated by BRENDA team
Kwak, G.H.; Lim, D.H.; Han, J.Y.; Lee, Y.S.; Kim, H.Y.
Methionine sulfoxide reductase B3 protects from endoplasmic reticulum stress in Drosophila and in mammalian cells
Biochem. Biophys. Res. Commun.
420
130-135
2012
Homo sapiens
Manually annotated by BRENDA team
Dobrovolska, O.; Rychkov, G.; Shumilina, E.; Nerinovski, K.; Schmidt, A.; Shabalin, K.; Yakimov, A.; Dikiy, A.
Structural insights into interaction between mammalian methionine sulfoxide reductase B1 and thioredoxin
J. Biomed. Biotechnol.
2012
586539
2012
Mus musculus (Q9JLC3)
Manually annotated by BRENDA team
Li, C.W.; Lee, S.H.; Chieh, P.S.; Lin, C.S.; Wang, Y.C.; Chan, M.T.
Arabidopsis root-abundant cytosolic methionine sulfoxide reductase B genes MsrB7 and MsrB8 are involved in tolerance to oxidative stress
Plant Cell Physiol.
53
1707-1719
2012
Arabidopsis thaliana
Manually annotated by BRENDA team
Le, D.T.; Tarrago, L.; Watanabe, Y.; Kaya, A.; Lee, B.C.; Tran, U.; Nishiyama, R.; Fomenko, D.E.; Gladyshev, V.N.; Tran, L.S.
Diversity of plant methionine sulfoxide reductases B and evolution of a form specific for free methionine sulfoxide
PLoS ONE
8
e65637
2013
Glycine max
Manually annotated by BRENDA team
Dai, C.; Liu, L.; Wang, M.H.
Characterization of a methionine sulfoxide reductase B from tomato (Solanum lycopersicum), and its protecting role in Saccharomyces cerevisiae
Protein J.
32
39-47
2013
Solanum lycopersicum
Manually annotated by BRENDA team
Aachmann, F.L.; Kwak, G.H.; Del Conte, R.; Kim, H.Y.; Gladyshev, V.N.; Dikiy, A.
Structural and biochemical analysis of mammalian methionine sulfoxide reductase B2
Proteins
79
3123-3131
2011
Mus musculus (Q78J03), Mus musculus
Manually annotated by BRENDA team
Liu, F.; Gong, Z.; Zhang, W.; Wang, Y.; Ma, L.; Wang, H.; Guo, X.; Xu, B.
Identification and characterization of a novel methionine sulfoxide reductase B gene (AccMsrB) from Apis cerana cerana (Hymenoptera Apidae)
Ann. Entomol. Soc. Am.
108
575-584
2015
Apis cerana cerana (A0A0F7Q005)
-
Manually annotated by BRENDA team
Chu, H.; Nguyen, K.; Watanabe, Y.; Le, D.; Tran, L.
Expression analyses of soybean genes encoding methionine-R-sulfoxide reductase under various conditions suggest a possible role in the adaptation to stress
Appl. Biol. Chem.
59
681-687
2016
Glycine max (C6SVM8), Glycine max (C6TFD8)
-
Manually annotated by BRENDA team
Han, A.R.; Kim, M.J.; Kwak, G.H.; Son, J.; Hwang, K.Y.; Kim, H.Y.
Essential role of the linker region in the higher catalytic efficiency of a bifunctional MsrA-MsrB fusion protein
Biochemistry
55
5117-5127
2016
Treponema denticola (Q73PT7), Treponema denticola, Treponema denticola ATCC 35405 (Q73PT7)
Manually annotated by BRENDA team
Ricci, F.; Lauro, F.; Grzymski, J.; Read, R.; Bakiu, R.; Santovito, G.; Luporini, P.; Vallesi, A.
The anti-oxidant defense system of the marine polar ciliate Euplotes nobilii Characterization of the MsrB gene family
Biology
6
E4
2017
Euplotes nobilii (A0A1Q1NIA4), Euplotes nobilii (A0A1Q1NIA7), Euplotes nobilii (A0A1Q1NIG3), Euplotes nobilii (K9ZU05), Euplotes nobilii 4Pyrm4 (A0A1Q1NIA4), Euplotes nobilii 4Pyrm4 (A0A1Q1NIA7), Euplotes nobilii 4Pyrm4 (A0A1Q1NIG3), Euplotes nobilii 4Pyrm4 (K9ZU05)
Manually annotated by BRENDA team
Saha, S.; Hashino, M.; Suzuki, J.; Uda, A.; Watanabe, K.; Shimizu, T.; Watarai, M.
Contribution of methionine sulfoxide reductase B (MsrB) to Francisella tularensis infection in mice
FEMS Microbiol. Lett.
364
fnw260
2017
Francisella tularensis subsp. holarctica (A0A0B3VNT0)
Manually annotated by BRENDA team
Jo, H.; Cho, Y.W.; Ji, S.Y.; Kang, G.Y.; Lim, C.J.
Protective roles of methionine-R-sulfoxide reductase against stresses in Schizosaccharomyces pombe
J. Basic Microbiol.
54
72-80
2014
Schizosaccharomyces pombe (J9USB3), Schizosaccharomyces pombe
Manually annotated by BRENDA team
Lim, C.J.; Jo, H.; Kim, K.
A protective role of methionine-R-sulfoxide reductase against cadmium in Schizosaccharomyces pombe
J. Microbiol.
52
976-981
2014
Schizosaccharomyces pombe (J9USB3), Schizosaccharomyces pombe
Manually annotated by BRENDA team
Bos, J.; Duverger, Y.; Thouvenot, B.; Chiaruttini, C.; Branlant, C.; Springer, M.; Charpentier, B.; Barras, F.
The sRNA RyhB regulates the synthesis of the Escherichia coli methionine sulfoxide reductase MsrB but not MsrA
PLoS ONE
8
e63647
2013
Escherichia coli (P0A746), Escherichia coli
Manually annotated by BRENDA team
Liu, L.; Wang, M.H.
Cloning, expression, and characterization of a methionine sulfoxide reductase B gene from Nicotiana tabacum
Protein J.
32
543-550
2013
Nicotiana tabacum
Manually annotated by BRENDA team
Javitt, G.; Cao, Z.; Resnick, E.; Gabizon, R.; Bulleid, N.J.; Fass, D.
Structure and electron-transfer pathway of the human methionine sulfoxide reductase MsrB3
Antioxid. Redox Signal.
33
665-678
2020
Homo sapiens (Q8IXL7), Homo sapiens
Manually annotated by BRENDA team
Xiao, L.; Jiang, G.; Yan, H.; Lai, H.; Su, X.; Jiang, Y.; Duan, X.
Methionine sulfoxide reductase B regulates the activity of ascorbate peroxidase of banana fruit
Antioxidants (Basel)
10
310
2021
Musa acuminata
Manually annotated by BRENDA team
Kim, S.; Lee, K.; Park, S.H.; Kwak, G.H.; Kim, M.S.; Kim, H.Y.; Hwang, K.Y.
Structural insights into a bifunctional peptide methionine sulfoxide reductase MsrA/B fusion protein from Helicobacter pylori
Antioxidants (Basel)
10
389
2021
Helicobacter pylori (O25011), Helicobacter pylori, Helicobacter pylori ATCC 700392 (O25011)
Manually annotated by BRENDA team
Lourenco Dos Santos, S.; Petropoulos, I.; Friguet, B.
The oxidized protein repair enzymes methionine sulfoxide reductases and their roles in protecting against oxidative stress, in ageing and in regulating protein function
Antioxidants (Basel)
7
191
2018
Homo sapiens (Q8IXL7), Homo sapiens (Q9NZV6)
Manually annotated by BRENDA team
Stolarska, E.; Bilska, K.; Wojciechowska, N.; Bagniewska-Zadworna, A.; Rey, P.; Kalemba, E.M.
Integration of MsrB1 and MsrB2 in the redox network during the development of orthodox and recalcitrant acer seeds
Antioxidants (Basel)
9
1250
2020
Acer pseudoplatanus, Acer platanoides
Manually annotated by BRENDA team
Cao, Z.; Mitchell, L.; Hsia, O.; Scarpa, M.; Caldwell, S.T.; Alfred, A.D.; Gennaris, A.; Collet, J.F.; Hartley, R.C.; Bulleid, N.J.
Methionine sulfoxide reductase B3 requires resolving cysteine residues for full activity and can act as a stereospecific methionine oxidase
Biochem. J.
475
827-838
2018
Homo sapiens (Q8IXL7)
Manually annotated by BRENDA team
Sasoni, N.; Hartman, M.; Guerrero, S.; Iglesias, A.; Arias, D.
Functional characterization of methionine sulfoxide reductases from Leptospira interrogans
Biochim. Biophys. Acta Proteins Proteom.
1869
140575
2021
Leptospira interrogans (Q72NN2), Leptospira interrogans Fiocruz L1-130 (Q72NN2)
Manually annotated by BRENDA team
Wen, Y.; Peng, L.; Zhou, Y.; Peng, T.; Chen, Y.; Cheng, X.; Chen, Y.; Yang, J.
Discovery and application of methionine sulfoxide reductase B for preparation of (S)-sulfoxides through kinetic resolution
Catal. Commun.
136
105908
2020
Acidovorax sp. KKS102 (K0HZZ3)
-
Manually annotated by BRENDA team
Xiao, T.; Mi, M.; Wang, C.; Qian, M.; Chen, Y.; Zheng, L.; Zhang, H.; Hu, Z.; Shen, Z.; Xia, Y.
A methionine-R-sulfoxide reductase, OsMSRB5, is required for rice defense against copper toxicity
Environ. Exp. Bot.
153
45-53
2018
Oryza sativa Japonica Group (Q10L32)
-
Manually annotated by BRENDA team
Guerrero, S.A.; Arias, D.G.; Cabeza, M.S.; Law, M.C.Y.; DAmico, M.; Kumar, A.; Wilkinson, S.R.
Functional characterisation of the methionine sulfoxide reductase repertoire in Trypanosoma brucei
Free Radic. Biol. Med.
112
524-533
2017
Trypanosoma brucei
Manually annotated by BRENDA team
Arias, D.G.; Cabeza, M.S.; Echarren, M.L.; Faral-Tello, P.; Iglesias, A.A.; Robello, C.; Guerrero, S.A.
On the functionality of a methionine sulfoxide reductase B from Trypanosoma cruzi
Free Radic. Biol. Med.
158
96-114
2020
Trypanosoma cruzi (V5BL87), Trypanosoma cruzi, Trypanosoma cruzi Dm28c (V5BL87)
Manually annotated by BRENDA team
Hage, H.; Rosso, M.N.; Tarrago, L.
Distribution of methionine sulfoxide reductases in fungi and conservation of the free-methionine-R-sulfoxide reductase in multicellular eukaryotes
Free Radic. Biol. Med.
169
187-215
2021
Yarrowia lipolytica, Yarrowia lipolytica (A0A1D8N9R8), Yarrowia lipolytica (Q6CCY5), Hortaea werneckii, Rhizopus microsporus var. chinensis, Crucibulum laeve, Dendrothele bispora, Tulasnella calospora, Ramaria rubella, Coprinellus micaceus, Smittium mucronatum, Smittium culicis, Gonapodya prolifera, Coniochaeta sp., Rhizopus microsporus (A0A1X0RU86), Absidia repens (A0A1X2IF91), Pichia kudriavzevii (A0A2U9QWX2), Smittium mucronatum ALG-7-W6, Yarrowia lipolytica YlCW001 v1.0, Rhizopus microsporus var. chinensis CCTCC M201021, Smittium culicis GSMNP, Rhizopus microsporus ATCC 11559 (A0A1X0RU86), Yarrowia lipolytica YB419 v1.0, Ramaria rubella UT-36052-T v1.0, Yarrowia lipolytica CLIB 122 (Q6CCY5), Dendrothele bispora CBS 962.96 v1.0, Yarrowia lipolytica CLIB 89 (W29) (A0A1D8N9R8), Crucibulum laeve CBS 166.37 v1.0, Yarrowia lipolytica YB566 v1.0, Pichia kudriavzevii CBS573 (A0A2U9QWX2), Yarrowia lipolytica YB567 v1.0, Yarrowia lipolytica YB420 v1.0, Coprinellus micaceus FP101781 v2.0, Yarrowia lipolytica FKP355 v1.0, Absidia repens NRRL 1336 (A0A1X2IF91), Hortaea werneckii EXF-2000 M0 v1.0, Yarrowia lipolytica PO1f v1.0, Tulasnella calospora AL13/4D v1.0
Manually annotated by BRENDA team
Wojciechowska, N.; Kalemba, E.; Bagniewska-Zadworna, A.; Minicka, J.; Michalak, K.
Localization and dynamics of the methionine sulfoxide reductases msrb1 and msrb2 in beech seeds
Int. J. Mol. Sci.
22
1-15
2021
Fagus sylvatica (A0A2N9F0L3)
Manually annotated by BRENDA team
He, Q.; Li, H.; Meng, F.; Sun, X.; Feng, X.; Chen, J.; Li, L.; Liu, J.
Methionine sulfoxide reductase B1 regulates hepatocellular carcinoma cell proliferation and invasion via the mitogen-activated protein kinase pathway and epithelial-mesenchymal transition
Oxid. Med. Cell. Longev.
2018
5287971
2018
Homo sapiens (Q9NZV6), Homo sapiens
Manually annotated by BRENDA team
Roy, S.; Nandi, A.
Arabidopsis thaliana methionine sulfoxide reductase B8 influences stress-induced cell death and effector-triggered immunity
Plant Mol. Biol.
93
109-120
2017
Arabidopsis thaliana (O49707), Arabidopsis thaliana
Manually annotated by BRENDA team
Shen, W.; Han, J.; Yan, P.; Zheng, J.; Zhang, L.; Li, X.; Tuo, D.; Zhou, P.
Soluble expression of biologically active methionine sulfoxide reductase B1 (PaMsrB1) from Carica papaya in Escherichia coli and isolation of its protein targets
Protein Expr. Purif.
146
17-22
2018
Carica papaya (F2YS22), Carica papaya
Manually annotated by BRENDA team
Lee, B.; Lee, S.; Choo, M.; Kim, J.; Lee, H.; Kim, S.; Fomenko, D.; Kim, H.; Park, J.; Gladyshev, V.
Selenoprotein MsrB1 promotes anti-inflammatory cytokine gene expression in macrophages and controls immune response in vivo /631/45/612 /631/250 /38 /82 /82/80 article
Sci. Rep.
7
5119
2017
Mus musculus (Q9JLC3)
Manually annotated by BRENDA team