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Disease on EC 1.8.1.7 - glutathione-disulfide reductase

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DISEASE
TITLE OF PUBLICATION
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Aberrant Crypt Foci
Multivitamin and mineral supplementation in 1,2-dimethylhydrazine induced experimental colon carcinogenesis and evaluation of free radical status, antioxidant potential, and incidence of ACF.
The modulatory influence of p-methoxycinnamic acid, an active rice bran phenolic acid, against 1,2-dimethylhydrazine-induced lipid peroxidation, antioxidant status and aberrant crypt foci in rat colon carcinogenesis.
Abortion, Habitual
Biochemical Markers of Oxidative Stress in Saudi Women with Recurrent Miscarriage.
Molecular and biochemical investigations of key antioxidant/oxidant molecules in Saudi patients with recurrent miscarriage.
Acidosis
Acidosis potentiates oxidative neuronal death by multiple mechanisms.
Acquired Immunodeficiency Syndrome
Effect of Naringenin (A naturally occurring flavanone) Against Pilocarpine-induced Status Epilepticus and Oxidative Stress in Mice.
Acute Kidney Injury
Morphology of renal tubular damage from nephrotoxins.
Role of glutathione in an animal model of myoglobinuric acute renal failure.
Adenocarcinoma
Activity of Antioxidant Enzymes in the Tumor and Adjacent Noncancerous Tissues of Non-Small-Cell Lung Cancer.
Antioxidant enzymes and lipid peroxidation in endometrium of patients with polyps, myoma, hyperplasia and adenocarcinoma.
Evidence of differential cisplatin-DNA adduct formation, removal and tolerance of DNA damage in three human lung carcinoma cell lines.
Inhibition of Prostaglandin Reductase 2, a Putative Oncogene Overexpressed in Human Pancreatic Adenocarcinoma, Induces Oxidative Stress-Mediated Cell Death Involving xCT and CTH Gene Expressions through 15-Keto-PGE2.
Oxidative DNA damage and disturbance of antioxidant capacity by alternariol in Caco-2 cells.
Role of NADPH oxidases in inducing a selective increase of oxidant stress and cyclin D1 and checkpoint 1 over-expression during progression to human gastric adenocarcinoma.
Adenocarcinoma of Lung
Effect of glutathione reductase knockdown in response to UVB-induced oxidative stress in human lung adenocarcinoma.
Adenoma
[Antioxidant system activities and lipid peroxidation in nodal and non-nodal thyroid tissue of patients operated in connection with euthyroid nodular goiter]
Aggressive Periodontitis
Influence of Periodontal Clinical Status on Salivary Levels of Glutathione Reductase.
Alopecia Areata
Evaluation of Glutathione Reductase and Glutathione Peroxidase in the Serum of Iranian Patients with Alopecia Areata: A Case-control Study.
Alzheimer Disease
Docosahexaenoic acid provides protection from impairment of learning ability in Alzheimer's disease model rats.
Elevated thiobarbituric acid-reactive substances and antioxidant enzyme activity in the brain in Alzheimer's disease.
Epicatechin Plus Treadmill Exercise are Neuroprotective Against Moderate-stage Amyloid Precursor Protein/Presenilin 1 Mice.
Hesperetin nanoparticles attenuate anxiogenic-like behavior and cerebral oxidative stress through the upregulation of antioxidant enzyme expression in experimental dementia of Alzheimer's type.
The activity of the pentose phosphate pathway is increased in response to oxidative stress in Alzheimer's disease.
Amyotrophic Lateral Sclerosis
Glutathione peroxidase in amyotrophic lateral sclerosis: the effects of selenium supplementation.
Low levels of selenium compounds are selectively toxic for a human neuron cell line through ROS/RNS increase and apoptotic process activation.
Oxidant-antioxidant imbalance in the erythrocytes of sporadic amyotrophic lateral sclerosis patients correlates with the progression of disease.
Time course of oxidant markers and antioxidant defenses in subgroups of amyotrophic lateral sclerosis patients.
Anaphylaxis
[Characteristics of the antioxidant system of alveolar surfactant in immediate-type allergies]
Anemia
Decreased reduced glutathione and glutathione reductase activity in subjects with hemoglobin C.
Effect of anaemia on red cell metabolism in cattle.
Erythrocyte glutathione reductase in iron deficiency anaemia.
Glutathione reductase deficiency of red cells in aplastic anemia. I. Red cell enzyme activities, glycolytic intermediates, adenine nucleotides and GSH levels in 11 cases with aplastic anemia.
Human erythrocyte glutathione reductase. II. Evidences for molecular aging of normal erythrocytes and apoenzyme defect in aplastic anemia.
Reduced antioxidant capacity in children with iron deficiency and iron-deficiency anemia.
The effect of experimental anaemia on red cell glutathione reductase.
The effect of oxidative stress on human red cells glutathione peroxidase, glutathione reductase level, and prevalence of anemia among diabetics.
The investigation of plasma glucose-6-phosphate dehydrogenase, 6-phoshogluconate dehydrogenase, glutathione reductase in premenauposal patients with iron deficiency anemia.
[Activity of glucose-6-phosphate dehydrogenase and glutathione reductase in early anemia of premature infants]
[Behavior of the glycolytic enzymes, glutathione reductase, phosphoric esters of adenosine, and reduced glutathione in the erythrocytes in some anemia states]
[Development of drug induced anemia in patients with glutathione reductase deficiency]
[Effects of sex difference on the toxicity of ethylene oxide. IV. Anemia]
[LEVEL OF GLUTATHIONE REDUCTASE IN THE BLOOD IN MILD ANEMIA IN CHILDREN. PRELIMINARY REPORT.]
[Lipid peroxidation in patients with iron deficiency anemia complicated by frequent acute respiratory diseases]
[Recovery study from anemia and alterations of glutathione metabolism in erythrocytes induced by chronic inhalation of ethylene oxide]
[The osmotic stability, glucose-6-phosphate dehydrogenase and glutathione reductase activity of the erythrocytes of leukemia and anemia patients]
Anemia, Aplastic
Glutathione reductase and riboflavin in hypoplastic anemia.
Glutathione reductase deficiency in red cells in aplastic anemia. II. Effects of flavine compounds on red cell glutathione reductase.
Glutathione reductase deficiency of red cells in aplastic anemia. I. Red cell enzyme activities, glycolytic intermediates, adenine nucleotides and GSH levels in 11 cases with aplastic anemia.
Human erythrocyte glutathione reductase. II. Evidences for molecular aging of normal erythrocytes and apoenzyme defect in aplastic anemia.
Idiosyncratic reactions: new methods of identifying high-risk patients.
[Relative deficiency of glutathione reductase and or pyruvate kinase in erythrocytes in aplastic anemia and acute leukemia]
Anemia, Hemolytic
Familial methaemoglobinaemia and haemolytic anaemia in the horse associated with decreased erythrocytic glutathione reductase and glutathione.
Glutathione reductase activity deficiency in homozygous Gr1a1Neu mice does not cause haemolytic anaemia.
Hemolytic anemia and pancytopenia in glutathione reductase deficiency: further experience with riboflavin.
Red Blood Cell Membrane Conductance in Hereditary Haemolytic Anaemias.
Relationship between glutathione reductase activity and drug-induced haemolytic anaemia.
[A new enzymopenic hemolytic anemia with glutathione reductase deficiency.]
[Activity of NADP and NAD dependable glutathione reductase in erythrocytes of children with hemolytic anemia]
[CONGENITAL NONSPHEROCYTIC HEMOLYTIC ANEMIA IN FAMILIAL DPNH AND TPNH-DEPENDENT GLUTATHIONE REDUCTASE DEFICIENCY OF THE ERYTHROCYTES. I.]
[Congenital, nonspherocytic, hemolytic anemia associated with familial DPNH- and TPNH-dependent glutathione reductase deficiency in the erythrocytes. II]
[Hemolytic anemia due to erythrocyte glutathione reductase deficiency: a familial case]
[Superoxide dismutase activity in the platelets of myeloproliferative disorders and of hemolytic anemia with glutathione reductase deficiency (author's transl)]
[Ulcer on white atrophy: hemolytic anemia caused by disulone revealing an erythrocytic glutathione reductase deficiency]
Anemia, Hemolytic, Congenital
Intra-erythrocytary enzymes before and after splenectomy.
[Glutathione reductase deficiency with membrane defect in hereditary hemolytic anemia]
Anemia, Hemolytic, Congenital Nonspherocytic
[CONGENITAL NONSPHEROCYTIC HEMOLYTIC ANEMIA IN FAMILIAL DPNH AND TPNH-DEPENDENT GLUTATHIONE REDUCTASE DEFICIENCY OF THE ERYTHROCYTES. I.]
[Congenital, nonspherocytic, hemolytic anemia associated with familial DPNH- and TPNH-dependent glutathione reductase deficiency in the erythrocytes. II]
Anemia, Iron-Deficiency
Erythrocyte glutathione reductase in iron deficiency anaemia.
The investigation of plasma glucose-6-phosphate dehydrogenase, 6-phoshogluconate dehydrogenase, glutathione reductase in premenauposal patients with iron deficiency anemia.
[Lipid peroxidation in patients with iron deficiency anemia complicated by frequent acute respiratory diseases]
Anemia, Sickle Cell
Decreased reduced glutathione and glutathione reductase activity in subjects with hemoglobin C.
Dependence of pyridoxine metabolism on riboflavin status in sickle cell patients.
Depressed erythrocyte glutathione reductase activity in sickle cell disease.
Impaired pentose phosphate shunt function in sickle cell disease: a potential mechanism for increased Heinz body formation and membrane lipid peroxidation.
Angina, Unstable
Glutathione reductase levels in patients with unstable angina.
Levels of glutathione reductase and glutathione peroxidase of human platelets in unstable angina and myocardial infarction.
The free radical system in ischemic heart disease.
Aortic Aneurysm
Glutathione system participation in thoracic aneurysms from patients with Marfan syndrome.
Aortic Coarctation
Aortic glutathione-related antioxidant defences in rabbits subjected to suprarenal aortic coarctation hypertension.
Arteriovenous Fistula
Role of the vagus nerves and catecholamines in the production mechanism of the myocardial failure induced by arteriovenous fistulas.
Arthritis
Induction of arthritis in mice and rats by potassium peroxochromate and assessment of disease activity by whole blood chemiluminescence and 99mpertechnetate-imaging.
Arthritis, Reactive
Glutathione reductase activity correlates with concentration of extracellular matrix.
Arthritis, Rheumatoid
A comparison of glutathione reductase and glutathione peroxidase activities in patients with rheumatoid arthritis and healthy adults.
Activity of Glutathione Antioxidant System and NADPH-Generating Enzymes in Rats with Experimental Rheumatoid Arthritis.
Beta-Carotene, Vitamin E, MDA, Glutathione Reductase and Arylesterase Activity Levels in Patients with Active Rheumatoid Arthritis.
Glutathione reductase activity correlates with concentration of extracellular matrix.
Glutathione reductase activity, riboflavin status, and disease activity in rheumatoid arthritis.
Impaired glutathione reductase activity and levels of collagenase and elastase in synovial fluid in rheumatoid arthritis.
The glutathione defense system in the pathogenesis of rheumatoid arthritis.
The interrelation of glutathione reductase, catalase, glutathione peroxidase, superoxide dismutase, and glucose-6-phosphate in the pathogenesis of rheumatoid arthritis.
[EFFECT OF MELATONIN ON THE GLUTATHIONE ANTIOXIDANT SYSTEM ACTIVITY IN RAT TISSUES UNDER CONDITIONS OF EXPERIMENTAL RHEUMATOID ARTHRITIS.]
[The effect of 3,5-dicarbomethoxyphenylbiguanide on the activity of antioxidant enzymes].
Ascorbic Acid Deficiency
Dietary vitamin C deficiency depressed the gill physical barriers and immune barriers referring to Nrf2, apoptosis, MLCK, NF-?B and TOR signaling in grass carp (Ctenopharyngodon idella) under infection of Flavobacterium columnare.
Dietary vitamin C deficiency depresses the growth, head kidney and spleen immunity and structural integrity by regulating NF-?B, TOR, Nrf2, apoptosis and MLCK signaling in young grass carp (Ctenopharyngodon idella).
Phagocytosis and leukocyte enzymes in ascorbic acid deficient guinea pigs.
[Study on changes of vitamin nutrition status of population in a high-risk area of esophageal cancer]
Asthma
Reduced superoxide dismutase in lung cells of patients with asthma.
Astrocytoma
Rapid colorimetric determination of reduced and oxidized glutathione using an end point coupled enzymatic assay.
Ataxia Telangiectasia
Isocyanates induces DNA damage, apoptosis, oxidative stress, and inflammation in cultured human lymphocytes.
Atherosclerosis
Dietary rice protein isolate attenuates atherosclerosis in apoE-deficient mice by upregulating antioxidant enzymes.
Increased expression of glutathione reductase in macrophages decreases atherosclerotic lesion formation in low-density lipoprotein receptor-deficient mice.
Reduced antioxidant capacity in children with iron deficiency and iron-deficiency anemia.
Avitaminosis
Changes in thiamin, riboflavin, niacin, beta-carotene, vitamins, C, A, D and E status of French Elderly Subjects during the first year of institutionalization.
Effect of oral contraceptive use on the erythrocytic glutathione reductase and aspartate aminotransferase activities in women with or without clinical signs of vitamin deficiency.
Bacterial Infections
Glutathione reductase is essential for host defense against bacterial infection.
Physiopathological responses of sole (Solea senegalensis) subjected to bacterial infection and handling stress after probiotic treatment with autochthonous bacteria.
beta-Thalassemia
[Detection of combined forms of hemoglobino- and enzymopathies in newborns]
Blister
Defects in antioxidant defense and calcium transport in the epidermis of xeroderma pigmentosum patients.
Effect of inhibition of the glutathione redox cycle on the ultrastructure of peroxide-treated rabbit epithelial cells.
Hermansky-Pudlak syndrome in a Swiss population.
Brain Contusion
Attenuation of brain nitrostative and oxidative damage by brain cooling during experimental traumatic brain injury.
Brain Death
Assessment of Oxidative Stress Markers in Hypothermic Preservation of Transplanted Kidneys.
Brain Edema
Inhibition of BECN1 Suppresses Lipid Peroxidation by Increasing System Xc- Activity in Early Brain Injury after Subarachnoid Hemorrhage.
[The effects of taurine on oxidative processes in brain edema].
Brain Injuries
Dauricine alleviated secondary brain injury after intracerebral hemorrhage by upregulating GPX4 expression and inhibiting ferroptosis of nerve cells.
Brain Injuries, Traumatic
Multiplexing of injury codes for the parallel operation of enzyme logic gates.
Brain Ischemia
Behavioral and histologic neuroprotection of aqueous garlic extract after reversible focal cerebral ischemia.
Changes in endogenous antioxidant enzymes during cerebral ischemia and reperfusion.
Effect of Saffron (Crocus sativus) on neurobehavioral and neurochemical changes in cerebral ischemia in rats.
Glutathione reductase during and after brain ischemia in gerbils.
Brain Neoplasms
Role of antioxidant enzymes in brain tumours.
The decrease in antioxidant potential in human brain tumours.
[Activity of glutathione peroxidase (GSH-Px), glutathione reductase (GSSG-R) and superoxide dismutase (SOD-1) in single brain metastasis]
[Activity of glutathione peroxidase (GSH-Px), glutathione reductase (GSSG-R) and superoxide dismutase in the brain tumors]
Breast Neoplasms
Antioxidant status and lipid peroxidation in the blood of breast cancer patients of different ages after chemotherapy with 5-fluorouracil, doxorubicin and cyclophosphamide.
Antioxidant status and lipid peroxidation in the blood of breast cancer patients of different ages.
Differential expression of glutathione S-transferase, glutathione peroxidase and glutathione reductase in normal and malignant human breast tissues.
Enhancement of the antineoplastic effect of mitomycin C by dietary fat.
Erythrocyte antioxidant enzyme activity in CMF treated breast cancer patients.
Increased oxidative stress created by adenoviral MnSOD or CuZnSOD plus BCNU (1,3-bis(2-chloroethyl)-1-nitrosourea) inhibits breast cancer cell growth.
Mutant p53 protein expression and antioxidant status deficiency in breast cancer.
Oxidant/Antioxidant Status, Lipids and Hormonal Profile in Overweight Women with Breast Cancer.
Taurine Regulates Mitochondrial Function During 7,12-Dimethyl Benz[a]anthracene Induced Experimental Mammary Carcinogenesis.
The organochlorine pesticide residues and antioxidant enzyme activities in human breast tumors: is there any association?
[Glutathione-dependent enzymes and glucose-6-phosphate dehydrogenase in breast tumors]
Carcinogenesis
Biochemical and biophysical study of chemopreventive and chemotherapeutic anti-tumor potential of some Egyptian plant extracts.
Chemoprevention by Hippophae rhamnoides: effects on tumorigenesis, phase II and antioxidant enzymes, and IRF-1 transcription factor.
Chemopreventive efficacy of lycopene on 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis.
Evaluation of oxidant-antioxidant status in tissue samples in oral cancer: A case control study.
Glutathione and glutathione-related enzymes in colorectal cancer patients.
Induction of glutathione-dependent hepatic biotransformation enzymes by lycopene in the hamster cheek pouch carcinogenesis model.
Carcinoma
Activity of Antioxidant Enzymes in the Tumor and Adjacent Noncancerous Tissues of Non-Small-Cell Lung Cancer.
Analysis of antioxidant defense systems during rat hepatocarcinogenesis.
Assessment of glutathione-S-transferase and glutathione reductase in patients with squamous-cell carcinoma of buccal mucosa.
Effect of Semecarpus anacardium Linn. nut milk extract on glutathione and its associated enzymes in experimentally induced mammary carcinoma.
Enhancement of the antineoplastic effect of mitomycin C by dietary fat.
Enzyme activities and level of SH groups in breast carcinomas.
Enzyme activities in human breast tumours.
Evidence of differential cisplatin-DNA adduct formation, removal and tolerance of DNA damage in three human lung carcinoma cell lines.
Glutathione reductase in human epidermal tumors. Basal and squamous cell epithelioma, verruca seborrhoeica.
Role of mitogen activated protein kinases in skin tumorigenicity of patulin.
Studies on glutathione metabolism in ventral prostate and chemically induced prostatic carcinoma in rats.
The effect of a novel taurine nitrosourea, 1-(2-chloroethyl)-3-[2-(dimethylaminosulfonyl)ethyl]-1-nitrosour ea (TCNU) on cytotoxicity, DNA crosslinking and glutathione reductase in lung carcinoma cell lines.
[Antioxidant system activities and lipid peroxidation in nodal and non-nodal thyroid tissue of patients operated in connection with euthyroid nodular goiter]
[The activity of redox-regulatory systems in the primary and recurrence tumors in vulvar cancer].
[THE MODE OF CLARIFYING DIAGNOSTIC OF PROGRESSING FORMS OF OVARIAN CARCINOMA].
Carcinoma, Ehrlich Tumor
Comparison of glutathione reductase activity and the intracellular glutathione reducing effects of 13 derivatives of 1'-acetoxychavicol acetate in Ehrlich ascites tumor cells.
Positive correlation between decreased cellular uptake, NADPH-glutathione reductase activity and adriamycin resistance in Ehrlich ascites tumor lines.
Carcinoma, Hepatocellular
Analysis of glutathione-dependent enzyme activities in two different rat hepatomas and in normal liver in relation to their role in resistance to oxidative stress.
Assay of free-radical toxicity and antioxidant effect on the Hep 3B cell line: a test survey using lindane.
Comparison of metabolic activities in two human hepatoma cell lines, HEP 3B and HEP G2. Application to lindane.
Effects of vitamins B1, B2, B6 and C on erythrocyte enzymes in South African Bantu.
Glutathione and GSH-dependent enzymes in patients with liver cirrhosis and hepatocellular carcinoma.
Glutathione reductase plays an anti-apoptotic role against oxidative stress in human hepatoma cells.
Nrf2-mediated induction of detoxifying enzymes by alantolactone present in Inula helenium.
[Glutathione reductase activity in erythrocytes of rats with transplantable Morris 5123 hepatoma]
[Latent form of glutathione reductase in the rat liver]
Carcinoma, Small Cell
Evidence of differential cisplatin-DNA adduct formation, removal and tolerance of DNA damage in three human lung carcinoma cell lines.
Carcinoma, Squamous Cell
Activity of Antioxidant Enzymes in the Tumor and Adjacent Noncancerous Tissues of Non-Small-Cell Lung Cancer.
Role of mitogen activated protein kinases in skin tumorigenicity of patulin.
[The activity of redox-regulatory systems in the primary and recurrence tumors in vulvar cancer].
Cardiac Complexes, Premature
Ventricular arrhythmias following exposure of failing hearts to oxidative stress in vitro.
Cardiomegaly
Role of the vagus nerves and catecholamines in the production mechanism of the myocardial failure induced by arteriovenous fistulas.
Cardiomyopathies
Isoproterenol-Induced Cardiomyopathy in Rats: Influence of Acorus calamus Linn. : A. calamus Attenuates Cardiomyopathy.
Cardiomyopathy, Alcoholic
Effect of chronic ethanol treatment under partial catalase inhibition on the activity of enzymes related to peroxide metabolism in rat liver and heart.
Cardiotoxicity
Cissampelos pareira Linn. ameliorates thyroxin-induced cardiac hypertrophy in rats.
Effect of doxorubicin on glutathione and glutathione-dependent enzymes in cultured rat heart cells.
Protective effect of Piper longum L. on oxidative stress induced injury and cellular abnormality in adriamycin induced cardiotoxicity in rats.
Sodium arsenite-induced cardiotoxicity in rats: protective role of p-coumaric acid, a common dietary polyphenol.
Cardiovascular Diseases
Redox status of patients before cardiac surgery.
Carpal Tunnel Syndrome
Enzymology of the response of the carpal tunnel syndrome to riboflavin and to combined riboflavin and pyridoxine.
Cataract
Ascorbate free radical reductase and ascorbate redox cycle in the human lens.
Biochemical changes and cataract formation in lenses from rats receiving multiple, low doses of sodium selenite.
Blood and lens lipid peroxidation and antioxidant status in normal individuals, senile and diabetic cataractous patients.
Cataracts and riboflavin deficiency.
Changes in glutathione, glutathione-linked enzymes and hexose monophosphate shunt enzymes in senile cataract.
Early onset steroid induced posterior subcapsular cataract in a patient with common variable immunodeficiency: case reports and review of literature.
Effects of low-carbohydrate diet and pycnogenol((r)) treatment on retinal antioxidant enzymes in normal and diabetic rats.
Effects of N-acetylcysteine and glutathione ethyl ester drops on streptozotocin-induced diabetic cataract in rats.
Enzyme activities in human lens epithelium of age-related cataract.
Glutathione and glutathione-related enzymes in human cataractous lenses.
Glutathione reductase from human cataract lenses can be revived by reducing agents and by a molecular chaperone, alpha-crystallin.
Glutathione reductase in human lens epithelium: FAD-induced in vitro activation.
Lens capsule and epithelium in age-related cataract.
Lupeol, a pentacyclic triterpenoid isolated from Vernonia cinerea attenuate selenite induced cataract formation in Sprague Dawley rat pups.
On the changes in the activity of glutathione reductase on the maturation of senile cataract.
Oral consumption of ?-glucosyl-hesperidin could prevent lens hardening, which causes presbyopia.
Preventive effect of danshensu on selenite-induced cataractogenesis in cultured rat lens.
Red blood cells and serum antioxidant defense systems of galactosaemic children.
Revival of glutathione reductase in human cataractous and clear lens extracts by thioredoxin and thioredoxin reductase, in conjunction with alpha-crystallin or thioltransferase.
Studies on glutathione S-transferase, glutathione peroxidase and glutathione reductase in human normal and cataractous lenses.
Celiac Disease
Antioxidant status and lipid peroxidation in small intestinal mucosa of children with celiac disease.
Glutathione redox cycle in small intestinal mucosa and peripheral blood of pediatric celiac disease patients.
Cerebral Hemorrhage
Dauricine alleviated secondary brain injury after intracerebral hemorrhage by upregulating GPX4 expression and inhibiting ferroptosis of nerve cells.
Cerebral Infarction
Cerebroprotective activity of Pentapetes phoenicea on global cerebral ischemia in rats.
Chagas Disease
Novel aryl ?-aminocarbonyl derivatives as inhibitors of Trypanosoma cruzi trypanothione reductase: binding mode revised by docking and GRIND2-based 3D-QSAR procedures.
Trypanothione reductase from Trypanosoma cruzi. Catalytic properties of the enzyme and inhibition studies with trypanocidal compounds.
Trypanothione reductase from Trypanosoma cruzi. Purification and characterization of the crystalline enzyme.
Chemical and Drug Induced Liver Injury
Expression of Glutathione Peroxidase and Glutathione Reductase and Level of Free Radical Processes under Toxic Hepatitis in Rats.
[Catalytic properties of glutathione reductase from rats liver at norm and toxic hepatitis]
[Thioctic acid action on glutathione-dependent antioxidant system functioning at toxic hepatitis of rats]
Cholestasis
Protective effect of Jasonia montana against ethinylestradiol-induced cholestasis in rats.
Cholestasis, Extrahepatic
Glucose phosphate isomerase and glutathione reductase in benign and malignant extrahepatic cholestasis.
Chronic Periodontitis
Association of salivary lipid peroxidation levels, antioxidant enzymes, and chronic periodontitis.
Evaluation of Antioxidant Enzymes Activity and Malondialdehyde Levels in Chronic Periodontitis Patients with Diabetes.
Influence of Periodontal Clinical Status on Salivary Levels of Glutathione Reductase.
Colitis
[Status of the glutathione system in gastroduodenal ulcers]
Colitis, Ulcerative
Colonic mucosal antioxidant enzymes and lipid peroxide levels in normal subjects and patients with ulcerative colitis.
Colonic Neoplasms
Anthocyanin Encapsulated by Ferulic Acid-Grafted-Maltodextrin (FA-g-MD) Microcapsules Potentially Improved its Free Radical Scavenging Capabilities Against H2O2-Induced Oxidative Stress.
Chemopreventive efficacy of ginger, a naturally occurring anticarcinogen during the initiation, post-initiation stages of 1,2 dimethylhydrazine-induced colon cancer.
Glutathione and mercapturic acid conjugates of sulofenur and their activity against a human colon cancer cell line.
Induction of oxidative cell damage by photo-treatment with zinc meta N-methylpyridylporphyrin.
Protective role of luteolin on the status of lipid peroxidation and antioxidant defense against azoxymethane-induced experimental colon carcinogenesis.
Colorectal Neoplasms
Activity of superoxide dismutase, catalase, glutathione peroxidase, and glutathione reductase in different stages of colorectal carcinoma.
AMPK?1 confers survival advantage of colorectal cancer cells under metabolic stress by promoting redox balance through the regulation of glutathione reductase phosphorylation.
Cystatin SN inhibits auranofin-induced cell death by autophagic induction and ROS regulation via glutathione reductase activity in colorectal cancer.
Coma
Glutathione metabolism is modulated by postmortem interval, gender difference and agonal state in postmortem human brains.
Plasma oxidants and antioxidants in acute ischaemic stroke.
[Energy metabolic changes and nerve cell damage in rats exposed to multiple administration of large-dose insulin].
Common Variable Immunodeficiency
Early onset steroid induced posterior subcapsular cataract in a patient with common variable immunodeficiency: case reports and review of literature.
Communicable Diseases
[Value of glutathione reductase and glucosephosphate isomerase measurements in infectious diseases]
Congenital Abnormalities
Toxicity of Aqueous L-Selenomethionine and Tert-Butyl Hydroperoxide Exposure to Zebrafish (Danio rerio) Embryos Following Tert-Butyl Hydroquinone Treatment.
Coronary Artery Disease
Redox status of patients before cardiac surgery.
Coronary Disease
Effect of lycopene from cooked tomatoes on serum antioxidant enzymes, lipid peroxidation rate and lipid profile in coronary heart disease.
Redox status of patients before cardiac surgery.
cystathionine beta-synthase deficiency
Cystathionine beta synthase deficiency induces catalase-mediated hydrogen peroxide detoxification in mice liver.
Cystic Fibrosis
Aberrant GSH reductase and NOX activities concur with defective CFTR to pro-oxidative imbalance in cystic fibrosis airways.
Letter: Serum glutathione reductase and cystic fibrosis.
Letter: White-cell glutathione reductase in cystic fibrosis.
Red cell glutathione and glutathione reductase in cystic fibrosis.
Serum glutathione reductase and cystic fibrosis.
Some biochemical indices of nutrition in treated cystic fibrosis patients.
[Serum glutathione reductase activity in children with mucoviscidosis]
Cytomegalovirus Infections
Morphofunctional characteristics of the glutathione cycle in peripheral blood erythrocytes of pregnant women with a history of cytomegalovirus infection exacerbation during gestation.
Dehydration
Antioxidant response of wheat roots to drought acclimation.
Antioxidative defense system, pigment composition, and photosynthetic efficiency in two wheat cultivars subjected to drought
Antioxidative protection in the inducible CAM plant Sedum album L. following the imposition of severe water stress and recovery.
Ascorbic acid mitigation of water stress-inhibition of root growth in association with oxidative defense in tall fescue (Festuca arundinacea Schreb.).
Cytological and physiological changes in orthodox maize embryos during cryopreservation.
Cytological and physiological changes in recalcitrant Chinese fan palm (Livistona chinensis) embryos during cryopreservation.
Effect of short-term water deficit stress on antioxidative systems in cucumber seedling roots.
Effect of water stress on antioxidant systems and oxidative parameters in fruits of tomato (Solanum lycopersicon L, cv. Micro-tom).
Effect of Water Stress on the Chloroplast Antioxidant System: I. Alterations in Glutathione Reductase Activity.
Effects of drying rate on dehydration sensitivity of excised wheat seedling shoots as related to sucrose metabolism and antioxidant enzyme activities.
Effects of water-saving superabsorbent polymer on antioxidant enzyme activities and lipid peroxidation in oat (Avena sativa L.) under drought stress.
Exogenous melatonin improves glutathione content, redox state and increases essential oil production in two Salvia species under drought stress.
Increased Drying Rate Lowers the Critical Water Content for Survival in Embryonic Axes of English Oak (Quercus robur L.) Seeds.
Nitric oxide reduces hydrogen peroxide accumulation involved in water stress-induced subcellular anti-oxidant defense in maize plants.
Nitric Oxide Signal, Nitrogen Metabolism, and Water Balance Affected by ?-Aminobutyric Acid (GABA) in Relation to Enhanced Tolerance to Water Stress in Creeping Bentgrass.
Piriformospora indica symbiosis improves water stress tolerance of rice through regulating stomata behavior and ROS scavenging systems.
Pretreatment with NaCl Promotes the Seed Germination of White Clover by Affecting Endogenous Phytohormones, Metabolic Regulation, and Dehydrin-Encoded Genes Expression under Water Stress.
Resurrection plants of the genus Ramonda: prospective survival strategies - unlock further capacity of adaptation, or embark on the path of evolution?
Role of abscissic acid in water stress-induced antioxidant defense in leaves of maize seedlings.
Role of antioxidant defenses in the tolerance of severe dehydration by anurans. The case of the leopard frog Rana pipiens.
The role of glutathione in yeast dehydration tolerance.
Water stress reveals differential antioxidant responses of tolerant and non-tolerant sugarcane genotypes.
Water stress-induced abscisic acid accumulation triggers the increased generation of reactive oxygen species and up-regulates the activities of antioxidant enzymes in maize leaves.
Dermatitis Herpetiformis
Analyses in blood of dermatological patients. I. Glutathione and glutathione reductase.
[Glutathione reductase deficiency in Duhring's dermatitis herpetiformis]
Diabetes Complications
Plasma malondialdehyde (MDA) and anti-oxidant status in diabetic retinopathy.
Recent Insights into the Nutritional Antioxidant Therapy in Prevention and Treatment of Diabetic Vascular Complications - A comprehensive Review.
The effect of oxidants on biomembranes and cellular metabolism.
Diabetes Mellitus
Activity of the glutathione antioxidant system and NADPH-generating enzymes in blood serum of rats with type 2 diabetes mellitus after administration of melatonin-correcting drugs.
Association of glomerular and tubular dysfunction with glycaemic control, lipid, lipoprotein, apolipoprotein and antioxidant status in type 2 diabetes mellitus.
Effect of Indian herbal hypoglycemic agents on antioxidant capacity and trace elements content in diabetic rats.
Glutathione and glutathione-metabolizing enzymes in the erythrocytes of healthy children and in children with insulin-dependent diabetes mellitus, juvenile rheumatoid arthritis, coeliac disease and acute lymphoblastic leukaemia.
Impaired glutathione-related antioxidant defenses in the arterial tissue of diabetic patients.
Influence of diabetes mellitus on the glutathione redox system of human red blood cells.
Negative association between erythrocyte reduced glutathione concentration and diabetic complications.
Plasma malondialdehyde (MDA) and anti-oxidant status in diabetic retinopathy.
The Role of Oxidative Stress in Diabetic Neuropathy: Generation of Free Radical Species in the Glycation Reaction and Gene Polymorphisms Encoding Antioxidant Enzymes to Genetic Susceptibility to Diabetic Neuropathy in Population of Type I Diabetic Patients.
[Antioxidant enzyme activity in the erythrocytes of rats with alloxan diabetes]
[Interrelation of diabetes mellitus, atherosclerosis and ischemic heart disease]
Diabetes Mellitus, Experimental
Changes in erythrocyte glutathione peroxidase and glutathione reductase in alloxan diabetes.
Diabetes Mellitus, Type 1
[Metabolism of riboflavin and B group vitamins functionally bound to it in insulin-dependent diabetes mellitus]
Diabetes Mellitus, Type 2
Activity of the glutathione antioxidant system and NADPH-generating enzymes in blood serum of rats with type 2 diabetes mellitus after administration of melatonin-correcting drugs.
Association of glomerular and tubular dysfunction with glycaemic control, lipid, lipoprotein, apolipoprotein and antioxidant status in type 2 diabetes mellitus.
Impaired glutathione-related antioxidant defenses in the arterial tissue of diabetic patients.
Increased plasma oxidizability and decreased erythrocyte and plasma antioxidative capacity in patients with NIDDM.
Metformin protects the brain against the oxidative imbalance promoted by type 2 diabetes.
Diabetic Retinopathy
Effects of low-carbohydrate diet and pycnogenol((r)) treatment on retinal antioxidant enzymes in normal and diabetic rats.
Drug-Related Side Effects and Adverse Reactions
Mitotic arrest, apoptosis, and sensitization to chemotherapy of melanomas by methionine deprivation stress.
Relationship of glutathione depletion and inhibition of glutathione-S-transferase activity to the antimitotic properties of estramustine.
Duodenal Ulcer
[Activity of glutathione-dependent enzymes and superoxide dismutase in peptic ulcer]
[Effect of quamatel on neutrophil properties, parameters of lipid peroxidation and the antioxidant defense system in blood of patients with duodenal ulcer and pancreatitis]
[New tableted protein products in the treatment of peptic ulcer patients and the dynamic indices of the glutathione system]
Dyslipidemias
Obesity decreases the oxidant stress induced by tobacco smoke in a rat model.
Eclampsia
Lipid peroxidation and antioxidant activity in complicated pregnancies.
Encephalomyelitis
Hydroxycitric acid ameliorates inflammation and oxidative stress in mouse models of multiple sclerosis.
[Lipid peroxidation and antioxidant defence enzyme activity in multiple sclerosis]
Encephalomyelitis, Autoimmune, Experimental
Hydroxycitric acid ameliorates inflammation and oxidative stress in mouse models of multiple sclerosis.
[Lipid peroxidation and antioxidant defence enzyme activity in multiple sclerosis]
Endotoxemia
Time course of nitric oxide, peroxynitrite, and antioxidants in the endotoxemic heart.
Epilepsy
Effect of add-on melatonin on seizure outcome, neuronal damage, oxidative stress, and quality of life in generalized epilepsy with generalized onset motor seizures in adults: A randomized controlled trial.
Effect of Naringenin (A naturally occurring flavanone) Against Pilocarpine-induced Status Epilepticus and Oxidative Stress in Mice.
Effects of add-on melatonin administration on antioxidant enzymes in children with epilepsy taking carbamazepine monotherapy: a randomized, double-blind, placebo-controlled trial.
Evaluation of the influence of antiepileptic therapy on antioxidant enzyme activity and lipid peroxidation in erythrocytes of children with epilepsy.
Serum and intraerythrocyte antioxidant enzymes and lipid peroxides in children with migraine.
[The effect of antiepileptic drug therapy on antioxidant enzyme activity and serum lipid peroxidation in young patients with epilepsy]
Epilepsy, Temporal Lobe
Effect of Naringenin (A naturally occurring flavanone) Against Pilocarpine-induced Status Epilepticus and Oxidative Stress in Mice.
Essential Hypertension
[Arterial hypertension in glomerulonephritis]
Fanconi Anemia
Superoxide dismutase and other biochemical disorders in a family with Fanconi's anemia.
Fascioliasis
Differential inhibition of rat hepatic glutathione S-transferase isoenzymes in the course of fascioliasis.
Fatty Liver
Oxidative stress and thyroid hormones in patients with liver diseases.
Fetal Diseases
Modulation of embryonic glutathione reductase and phenytoin teratogenicity by 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU).
Molecular and biochemical mechanisms in teratogenesis involving reactive oxygen species.
Fibromyalgia
Absence of correlation between magnesium and riboflavin status.
Folic Acid Deficiency
Folic acid deficiency impairs the gill health status associated with the NF-?B, MLCK and Nrf2 signaling pathways in the gills of young grass carp (Ctenopharyngodon idella).
The coexistence of other micronutrient deficiencies in anaemic adolescent schoolgirls in rural Bangladesh.
Foot-and-Mouth Disease
Agroinfiltration contributes to VP1 recombinant protein degradation.
Friedreich Ataxia
Abnormalities of antioxidant metabolism in a case of Friedreich's disease.
Abnormalities of glutathione peroxidase and glutathione reductase in four patients with Friedreich's disease.
Galactosemias
Abnormalities of retinal metabolism in diabetes or experimental galactosemia. IV. Antioxidant defense system.
Gallstones
Antilithogenic influence of dietary capsaicin and curcumin during experimental induction of cholesterol gallstone in mice.
Gaucher Disease
[Gaucher's disease with glutathione reductase deficiency in the blood cells]
Glioblastoma
Glutathione peroxidase, glutathione reductase and protein oxidation in patients with glioblastoma multiforme and transitional meningioma.
Glutathione reductase mediates drug resistance in glioblastoma cells by regulating redox homeostasis.
Glioma
The non-psychoactive cannabidiol triggers caspase activation and oxidative stress in human glioma cells.
Glomerulonephritis
[Arterial hypertension in glomerulonephritis]
glucose-6-phosphate dehydrogenase (nadp+) deficiency
A series of new screening procedures for pyruvate kinase deficiency, glucose-6-phosphate dehydrogenase deficiency, and glutathione reductase deficiency.
Case studies on haemoglobin S heterozygotes with severe clinical manifestations.
Enhanced binding of FAD to glutathione reductase in G6PD deficiency.
Erythrocyte glutathione reductase in gout and in glucose-6-phosphate dehydrogenase deficiency.
Frequency of glutathione reductase, pyruvate kinase and glucose-6-phosphate dehydrogenase deficiency in a Spanish population.
Glucose-6-phosphate dehydrogenase deficiency in females, diagnosed by partial inhibition of glutathione reductase activity in the erythrocytes after incubation with chromate.
Glutathione reductase activity and its relationship to pyridoxine phosphate activity in G6PD deficiency.
Glutathione reductase-deficient erythrocytes as host cells of malarial parasites.
Influence of glucose-6-phosphate dehydrogenase deficiency on the glutathione reductase test for ariboflavinosis.
NADP+ and NADPH in glucose-6-phosphate dehydrogenase-deficient erythrocytes under oxidative stimulation.
Red Blood Cell Membrane Conductance in Hereditary Haemolytic Anaemias.
Glucosephosphate Dehydrogenase Deficiency
A series of new screening procedures for pyruvate kinase deficiency, glucose-6-phosphate dehydrogenase deficiency, and glutathione reductase deficiency.
Enhanced binding of FAD to glutathione reductase in G6PD deficiency.
Erythrocyte glutathione reductase in gout and in glucose-6-phosphate dehydrogenase deficiency.
Frequency of glutathione reductase, pyruvate kinase and glucose-6-phosphate dehydrogenase deficiency in a Spanish population.
Glucose-6-phosphate dehydrogenase deficiency in females, diagnosed by partial inhibition of glutathione reductase activity in the erythrocytes after incubation with chromate.
Glutathione reductase activity and its relationship to pyridoxine phosphate activity in G6PD deficiency.
Glutathione reductase-deficient erythrocytes as host cells of malarial parasites.
Influence of glucose-6-phosphate dehydrogenase deficiency on the glutathione reductase test for ariboflavinosis.
NADP+ and NADPH in glucose-6-phosphate dehydrogenase-deficient erythrocytes under oxidative stimulation.
Red Blood Cell Membrane Conductance in Hereditary Haemolytic Anaemias.
glutamate-cysteine ligase deficiency
Red Blood Cell Membrane Conductance in Hereditary Haemolytic Anaemias.
glutathione-disulfide reductase deficiency
A series of new screening procedures for pyruvate kinase deficiency, glucose-6-phosphate dehydrogenase deficiency, and glutathione reductase deficiency.
Case studies on haemoglobin S heterozygotes with severe clinical manifestations.
Consequences of erythrocytic glutathione reductase deficiency.
Deficiency of two red-cell flavin enzymes in a population in Sardinia: was glutathione reductase deficiency specifically selected for by malaria?
Disorders of respiratory burst termination.
Erythrocytic glutathione reductase deficiency in a hospital population in the United States.
Glutathione metabolism of the red cells. Effect of glutathione reductase deficiency on the stimulation of hexose monophosphate shunt under oxidative stress.
Glutathione reductase deficiency alters lung development and hyperoxic responses in neonatal mice.
Glutathione reductase deficiency and platelet dysfunction induced by 1,3-bis(2-chloroethyl)-1-nitrosourea.
Glutathione reductase deficiency in a kindred with hereditary spherocytosis.
Glutathione reductase deficiency in association with sickle cell and thalassaemia genes in Saudi populations.
Glutathione reductase deficiency in red cells in aplastic anemia. II. Effects of flavine compounds on red cell glutathione reductase.
Glutathione reductase deficiency in Saudi Arabia.
Glutathione reductase deficiency of red cells in aplastic anemia. I. Red cell enzyme activities, glycolytic intermediates, adenine nucleotides and GSH levels in 11 cases with aplastic anemia.
Glutathione reductase in the south-western province of Saudi Arabia--genetic variation vs. acquired deficiency.
Hematologic and biochemical observations in Gazella dama, G. dorcas and G. cuvieri.
Hemolytic anemia and pancytopenia in glutathione reductase deficiency: further experience with riboflavin.
Hereditary erythrocyte glutathione reductase deficiency.
Inherited glutathione reductase deficiency and Plasmodium falciparum malaria--a case study.
Isoniazid acetylating phenotype in patients with paracoccidioidomycosis and its relationship with serum sulfadoxin levels, glucose-6-phosphate dehydrogenase and glutathione reductase activities.
Lens capsule and epithelium in age-related cataract.
Macrophage endoplasmic reticulum (ER) proteins and reducing elements stabilize paraoxonase 2 (PON2).
Molecular basis of glutathione reductase deficiency in human blood cells.
Partial glutathione reductase deficiency as a cause of diverse clinical manifestations in a family with unstable hemoglobin (Hemoglobin Haná, ?63(E7) His-Asn).
Protection of phagocytic leukocytes by endogenous glutathione: studies in a family with glutathione reductase deficiency.
Severe generalized glutathione reductase deficiency after antitumor chemotherapy with BCNU" [1,3-bis(chloroethyl)-1-nitrosourea].
Visual test for erythrocytic glucose-6-phosphate dehydrogenase, 6-phosphogluconic dehydrogenase, and glutathione reductase deficiencies.
[A new enzymopenic hemolytic anemia with glutathione reductase deficiency.]
[BIOCHEMICAL FINDINGS IN FEMALE HETEROZYGOTIC CARRIERS OF GLUTATHIONE REDUCTASE DEFICIENCY WITH MUSHROOM POISONING.]
[CONGENITAL NONSPHEROCYTIC HEMOLYTIC ANEMIA IN FAMILIAL DPNH AND TPNH-DEPENDENT GLUTATHIONE REDUCTASE DEFICIENCY OF THE ERYTHROCYTES. I.]
[Congenital, nonspherocytic, hemolytic anemia associated with familial DPNH- and TPNH-dependent glutathione reductase deficiency in the erythrocytes. II]
[Deficiency of leukocyte glutathione reductase, deficiency of leukocyte glutathione peroxidase]
[Development of drug induced anemia in patients with glutathione reductase deficiency]
[Enzyme deficiencies of blood cells in bone marrow insufficiency (author's transl]
[Familial glutathione reductase deficiency and disorder of glutathione synthesis in the erythrocyte]
[Family studies on glutathione reductase deficiency in human erythrocytes]
[Gaucher's disease with glutathione reductase deficiency in the blood cells]
[Glutathione reductase deficiency in Duhring's dermatitis herpetiformis]
[Glutathione reductase deficiency with hematological and neurologic disorders. (Autosomal dominant hereditary formation of a pathological enzyme)]
[Glutathione reductase deficiency with membrane defect in hereditary hemolytic anemia]
[Glutathione reduction in erythrocytes of healthy persons and enzyme defect carriers. Use of the azoester test by Kosower et al. in glucose-6-P-dehydrogenase and glutathione reductase deficiency]
[Hb C homozygosity with glutathione reductase deficiency in the blood cells]
[Hemolytic anemia due to erythrocyte glutathione reductase deficiency: a familial case]
[March hemoglobinuria. One case with erythrocyte glutathione peroxidase deficiency]
[On a simultaneous occurrence of a glutathione reductase deficiency, a heme synthesis disorder and an Hb-F increase in the erythrocytes]
[Pancytopenias with erythrocyte pyruvate kinase- and glutathione reductase deficiencies]
[Purification of the erythrocyte glutathione reductase in normal subjects and patients with glutathione reductase deficiency]
[Spontaneous and chloramphenicol-induced chromosome mutations and biochemical data in 2 cases with glutathione reductase deficiency (NAD(P)H: glutathione oxidoreductase, E.C.1.6.4.2.)]
[Superoxide dismutase activity in the platelets of myeloproliferative disorders and of hemolytic anemia with glutathione reductase deficiency (author's transl)]
[Transient pyruvate kinase- and glutathione reductase deficiency of erythrocytes in chronic idiopathic infantile pancytopenia]
[Ulcer on white atrophy: hemolytic anemia caused by disulone revealing an erythrocytic glutathione reductase deficiency]
Glycogen Storage Disease
[Interrelationship between purine, carbohydrate, lipid and aminoacid metabolism, in hyperuricaemia and gout (author's transl)]
Glycogen Storage Disease Type I
[Interrelationship between purine, carbohydrate, lipid and aminoacid metabolism, in hyperuricaemia and gout (author's transl)]
Gout
Effect of treatment on erythrocyte phosphoribosyl pyrophosphate synthetase and glutathione reductase activity in patients with primary gout.
Erythrocyte glutathione reductase in gout and in glucose-6-phosphate dehydrogenase deficiency.
Glutathione reductase in red blood cells: variant associated with gout.
Phosphoribosyl pyrophosphate synthetase and glutathione reductase in erythrocytes from hyperuricaemic and gout patients.
Head and Neck Neoplasms
Serum glutathione-S-transferase and glutathione reductase activity in head and neck cancer patients.
Head Injuries, Closed
Antioxidant mechanisms in apolipoprotein E deficient mice prior to and following closed head injury.
Hearing Loss
Changes in cochlear antioxidant enzyme activity after sound conditioning and noise exposure in the chinchilla.
Evaluating protective and therapeutic effects of alpha-lipoic acid on cisplatin-induced ototoxicity.
Heart Arrest
Oxidative stress reversibly inactivates myocardial enzymes during cardiac arrest.
Heart Failure
B-vitamin deficiency in hospitalized patients with heart failure.
Oxy free radical system in heart failure and therapeutic role of oral vitamin E.
Role of the vagus nerves and catecholamines in the production mechanism of the myocardial failure induced by arteriovenous fistulas.
Hemorrhagic Stroke
Lipid peroxidation, hemolysis and antioxidant enzymes of erythrocytes in stroke.
Plasma values of oxidants and antioxidants in acute brain hemorrhage: role of free radicals in the development of brain injury.
Hepatic Encephalopathy
[Status of the processes of free-radical oxidation and the antioxidation system in patients with a severe course of hepatitis B]
Hepatitis
Clinical significance of serum glutathione reductase in various clinical conditions, especially in liver diseases.
Metabolism of mutagens and carcinogens in woodchuck liver and its relationship with hepatitis virus infection.
[Lactate dehydrogenase, glucosephosphate dehydrogenase, glutathione reductase and adenosine triphosphatase activities in the erythrocytes of patients with acute viral hepatitis]
[The erythrocyte antioxidant system in chronic liver diseases]
Hepatitis B
[Status of the processes of free-radical oxidation and the antioxidation system in patients with a severe course of hepatitis B]
Hepatitis B, Chronic
Circulating Biomarkers and their Possible Role in Pathogenesis of Chronic Hepatitis B and C Viral Infections.
Hepatitis C
Circulating Biomarkers and their Possible Role in Pathogenesis of Chronic Hepatitis B and C Viral Infections.
Perioperative levels of glutathione reductase in liver transplant recipients with hepatitis C virus cirrhosis.
Hepatitis C, Chronic
Antioxidant status and glutathione metabolism in peripheral blood mononuclear cells from patients with chronic hepatitis C.
Hepatitis, Alcoholic
The effect of melaxen on the activity of caspases and the glutathione antioxidant system in toxic liver injury.
Hepatitis, Autoimmune
Oxidative stress and antioxidant status in patients with autoimmune liver diseases.
Hepatitis, Chronic
Clinical significance of serum glutathione reductase in various clinical conditions, especially in liver diseases.
Metabolism of mutagens and carcinogens in woodchuck liver and its relationship with hepatitis virus infection.
[Status of the glutathione system in gastroduodenal ulcers]
[The activity of the glutathione-dependent enzymes of erythrocytes in chronic liver diseases in children]
Hepatoblastoma
Structure-activity relationships for the impact of selected isothiazol-3-one biocides on glutathione metabolism and glutathione reductase of the human liver cell line Hep G2.
Hepatomegaly
A novel dairy product fermented with Propionibacterium freudenreichii improves the riboflavin status of deficient rats.
Ingestion of milk fermented by genetically modified Lactococcus lactis improves the riboflavin status of deficient rats.
Herpes Zoster
Are Atlantic cod in Store Lungegårdsvann, a seawater recipient in Bergen, affected by environmental contaminants? A qRT-PCR survey.
Hodgkin Disease
[The glutathione enzymatic redox system in the blood of patients with lymphoproliferative diseases]
Homocystinuria
Cystathionine beta synthase deficiency induces catalase-mediated hydrogen peroxide detoxification in mice liver.
Hyperglycemia
Diabetes, oxidative stress, and antioxidants: a review.
Effect of thiamine pyrophosphate on retinopathy induced by hyperglycemia in rats: A biochemical and pathological evaluation.
Effects of Combination of Thiazolidinediones with Melatonin in Dexamethasone-induced Insulin Resistance in Mice.
Erythrocyte sodium-potassium ATPase activity and thiol metabolism in genetically hyperglycemic mice.
Glucose-6-phosphate dehydrogenase activity and NADPH/NADP+ ratio in liver and pancreas are dependent on the severity of hyperglycemia in rat.
Glutathione depletion in the lens of galactosemic and diabetic rats.
Instant White Rice with Pigmented Giant Embryonic Rice Improves Glucose Metabolism and Inhibits Oxidative Stress in High-Fat Diet-Fed Mice.
Parameters of antioxidative defense in type 2 diabetic patients with cardiovascular complications.
Regulation mechanism of oxidative stress induced by high glucose through PI3K/Akt/Nrf2 pathway in juvenile blunt snout bream (Megalobrama amblycephala).
Hyperlipidemias
Hovenia Dulcis Extract Reduces Lipid Accumulation in Oleic Acid-Induced Steatosis of Hep G2 Cells via Activation of AMPK and PPAR?/CPT-1 Pathway and in Acute Hyperlipidemia Mouse Model.
Hypersensitivity
Early onset steroid induced posterior subcapsular cataract in a patient with common variable immunodeficiency: case reports and review of literature.
Reverse genetic analysis of the glutathione metabolic pathway suggests a novel role of PHGPX and URE2 genes in aluminum resistance in Saccharomyces cerevisiae.
The AMPK Family Member Snf1 Protects Saccharomyces cerevisiae Cells upon Glutathione Oxidation.
Hypertension
Antioxidant enzymes and effects of tempol on the development of hypertension induced by nitric oxide inhibition.
Aortic glutathione-related antioxidant defences in rabbits subjected to suprarenal aortic coarctation hypertension.
Cardiac and renal antioxidant enzymes and effects of tempol in hyperthyroid rats.
Glutathione-related antioxidant defense system in patients with hypertensive retinopathy.
Grape powder supplementation prevents oxidative stress-induced anxiety-like behavior, memory impairment, and high blood pressure in rats.
[Arterial hypertension in glomerulonephritis]
[CHANGES IN THE METABOLISM IN THE MYOCARDIUM OF RATS WITH ARTERIAL HYPERTENSION].
Hypertensive Retinopathy
Glutathione-related antioxidant defense system in patients with hypertensive retinopathy.
Hyperthyroidism
Adaptation of red cell enzymes and intermediates in metabolic disorders.
Biochemical evaluation of oxidative stress in propylthiouracil treated hyperthyroid patients. Effects of vitamin C supplementation.
Cardiac and renal antioxidant enzymes and effects of tempol in hyperthyroid rats.
Cissampelos pareira Linn. ameliorates thyroxin-induced cardiac hypertrophy in rats.
Effect of thyroid state on lipid peroxidation, antioxidant defences, and susceptibility to oxidative stress in rat tissues.
Expression of hepatic antioxidant genes in l-thyroxine-induced hyperthyroid rats: regulation by vitamin E and curcumin.
Melatonin enhances antioxidant defenses but could not ameliorate the reproductive disorders in induced hyperthyroidism model in male rats.
The impact of thyroid activity variations on some oxidizing-stress parameters in rats.
The response of rat liver lipid peroxidation, antioxidant enzyme activities and glutathione concentration to the thyroid hormone.
Tri-iodo thyronine regulates antioxidant enzyme activities in different cell fractions through a mechanism sensitive to actinomycin D in a teleost, Anabas testudineus (Bloch).
[The effect of one-month antithyroid therapy on peripheral metabolism of reactive oxygen species in Graves' disease with infiltrative ophthalmopathy]
Hypoglossal Nerve Injuries
Simultaneous expression of glutathione, thioredoxin-1, and their reductases in nerve transected hypoglossal motor neurons of rat.
Hypoglycemia
Adaptation of red cell enzymes and intermediates in metabolic disorders.
Cortical and hippocampal mitochondria bioenergetics and oxidative status during hyperglycemia and/or insulin-induced hypoglycemia.
Effect of starvation and insulin-induced hypoglycemia on oxidative stress scavenger system and electron transport chain complexes from rat brain, liver, and kidney.
Hypokinesia
Does antioxidant system adaptive response alleviate related oxidative damage with long term bed rest?
[Enzyme system of initiation and protection against lipid peroxidation in the liver and blood of rats with hypokinesia]
Hypothyroidism
Absence of correlation between magnesium and riboflavin status.
Hypothyroidism impairs antioxidant defence system and testicular physiology during development and maturation.
Protein-chemical standardization of the erythrocyte glutathione reductase activation test (EGRAC test). Application to hypothyroidism.
Riboflavin metabolism in the hypothyroid newborn.
Thyroid hormones regulate lipid peroxidation and antioxidant enzyme activities in Anabas testudineus (Bloch).
Infections
Alteration of free radical metabolism in the brain of mice infected with scrapie agent.
Alterations of the glutathione cycle enzymes during and after SV40-transformation of human fibroblasts.
Antimalarial efficacy of methylene blue and menadione and their effect on glutathione metabolism of Plasmodium yoelii-infected albino mice.
Biochemical characterization of compatible plant-viral interaction: A case study with a Begomovirus-Kenaf host-pathosystem.
Ceratonia siliqua pod extract ameliorates Schistosoma mansoni-induced liver fibrosis and oxidative stress.
Changes in expression and activity of glutathione S-transferase in different organs of schistosoma haematobium-infected hamster.
Changes in rodent-erythrocyte methemoglobin reductase system produced by two malaria parasites, viz. Plasmodium yoelii nigeriensis and Plasmodium berghei.
Changes in the activities of antioxidant enzymes in response to virus infection and hormone treatment.
Dietary vitamin C deficiency depressed the gill physical barriers and immune barriers referring to Nrf2, apoptosis, MLCK, NF-?B and TOR signaling in grass carp (Ctenopharyngodon idella) under infection of Flavobacterium columnare.
Different levels of Schistosoma mansoni infection induce changes in drug-metabolizing enzymes.
Effect of beta-arteether treatment on erythrocytic methemoglobin reductase system in Plasmodium yoelii nigeriensis infected mice.
Effect of picroliv on glutathione metabolism in liver and brain of Mastomys natalensis infected with Plasmodium berghei.
Effect of respiratory infection on tissue riboflavin and flavin enzymes in mice.
Enzymatic activity of peripheral blood erythrocytes in pregnant women with exacerbation of herpesvirus infection.
Gingival Periodontal Disease (PD) Level-Butyric Acid Affects the Systemic Blood and Brain Organ: Insights Into the Systemic Inflammation of Periodontal Disease.
Glutathione Reductase Promotes Fungal Clearance and Suppresses Inflammation during Systemic Candida albicans Infection in Mice.
Glutathione synthesis is compromised in erythrocytes from individuals with HIV.
Gut pathology and responses to the microsporidium Nosema ceranae in the honey bee Apis mellifera.
In vitro Staphylococcus aureus-induced oxidative stress in mice murine peritoneal macrophages: a duration-dependent approach.
In vitro time-dependent vancomycin-resistant Staphylococcus aureus-induced free radical generation and status of antioxidant enzymes in murine peritoneal macrophage.
Liver endogenous antioxidant defenses in mice fed AIN-76A diet and infected with murine AIDS.
Melatonin restores neutrophil functions and prevents apoptosis amid dysfunctional glutathione redox system.
Mild riboflavin deficiency is highly prevalent in school-age children but does not increase risk for anaemia in Côte d'Ivoire.
Neutrophil superoxide anion production, and CAT and GSSGR activity in patients with tuberculosis.
Opportunistic Pathogen Porphyromonas gingivalis Modulates Danger Signal ATP-Mediated Antibacterial NOX2 Pathways in Primary Epithelial Cells.
Riboflavin deficiency and severity of malaria.
Role of intracellular second messengers and reactive oxygen species in the pathophysiology of V. cholera O139 treated rabbit ileum.
Status of hepatic oxidative stress and antioxidant defense systems during chloroquine treatment of Plasmodium yoelii nigeriensis infected mice.
Studies on hepatic oxidative stress and antioxidant defence systems during arteether treatment of Plasmodium yoelii nigeriensis infected mice.
Systemic effects on leaf glutathione metabolism and defence protein expression caused by esca infection in grapevines.
The potential of melatonin in reducing morbidity-mortality after craniocerebral trauma.
The Redox Systems of Plasmodium falciparum and Plasmodium vivax: Comparison, In silico Analyses and Inhibitor Studies.
The use of pentoxifylline as adjuvant therapy with praziquantel downregulates profibrogenic cytokines, collagen deposition and oxidative stress in experimental schistosomiasis mansoni.
Up-regulation of the ascorbate-dependent antioxidative system in barley leaves during powdery mildew infection.
White spot syndrome virus infection decreases the activity of antioxidant enzymes in Fenneropenaeus indicus.
[Antioxidants and immunomodulating action of antibiotics and antibiotic-treated erythrocytes in staphylococcal infections]
Infertility
Association of oxidative stress with female infertility - A case control study.
Markers of oxidative stress in follicular fluid of women with endometriosis and tubal infertility undergoing IVF.
Influenza, Human
Rigid protein motion as a model for crystallographic temperature factors.
Insulin Resistance
Effects of Combination of Thiazolidinediones with Melatonin in Dexamethasone-induced Insulin Resistance in Mice.
Effects of Huangjiu, Baijiu and Red Wine Combined With High-Fat Diet on Glucose and Lipid Metabolism: Aggravate or Alleviate?
Structural basis for catalytic and inhibitory mechanisms of human prostaglandin reductase PTGR2.
Type 2 diabetic patients with ischemic stroke: decreased insulin sensitivity and decreases in antioxidant enzyme activity are related to different stroke subtypes.
Intervertebral Disc Degeneration
The Evaluation of Glutathione Reductase and Malondialdehyde Levels in Patients With Lumbar Disc Degeneration Disease.
Intestinal Volvulus
Molecular characterization and expression of Onchocerca volvulus glutathione reductase.
Iron Deficiencies
Pyrimidine 5'nucleotidase and several other red cell enzyme activities in beta-thalassaemia trait.
Reduced antioxidant capacity in children with iron deficiency and iron-deficiency anemia.
Iron Overload
Activities of some free-radical scavenging enzymes and glutathione concentrations in human and rat liver and their relationship to the pathogenesis of tissue damage in iron overload.
In vitro and in vivo effects of iron on the expression and activity of glucose 6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase, and glutathione reductase in rat spleen.
Irritable Bowel Syndrome
Evaluation of glutathione reductase activity in colon tissue of patients with irritable bowel syndrome.
Ischemic Stroke
Plasma oxidants and antioxidants in acute ischaemic stroke.
Jaundice, Neonatal
Jaundice in new born and erythrocyte and plasma antioxidant defence system.
Keratitis
Corneal aldehyde dehydrogenase, glutathione reductase, and glutathione S-transferase in pathologic corneas.
Keratitis, Herpetic
[Enzymatic analysis of lacrimal fluid in viral keratitis]
Keratoconus
Corneal aldehyde dehydrogenase, glutathione reductase, and glutathione S-transferase in pathologic corneas.
Kidney Failure, Chronic
Serum and erythrocyte glutathione reductase activity in chronic renal failure.
The role of the oxidative state of glutathione and glutathione-related enzymes in anemia of hemodialysis patients.
[Catalytic activity of glutathione reductase in erythrocytes in chronic kidney failure]
Kwashiorkor
Glutathione and association antioxidant systems in protein energy malnutrition: results of a study in Nigeria.
Leishmaniasis
Trypanothione reductase activity is prominent in metacyclic promastigotes and axenic amastigotes of Leishmania amazonesis. Evaluation of its potential as a therapeutic target.
Leprosy
Erythrocyte glutathione peroxidase, glutathione reductase activities and blood glutathione content in leprosy.
Leukemia
Activities of enzyme transducing extracellular signals--gamma glutamyltransferase and enzymes metabolizing glutathione in acute lymphoblastic and myeloid human leukemias.
Adenosine acts as an endogenous activator of the cellular antioxidant defense system.
Bis(2-hydroxybenzylidene)acetone, a potent inducer of the phase 2 response, causes apoptosis in mouse leukemia cells through a p53-independent, caspase-mediated pathway.
Characterization of the inhibition of glutathione reductase and the recovery of enzyme activity in exponentially growing murine leukemia (L1210) cells treated with 1,3-bis(2-chloroethyl)-1-nitrosourea.
Glutathione, cell proliferation, and 1,3-bis-(2-chloroethyl)-1-nitrosourea in K562 leukemia.
IV-evaluation of plasma glutathione reductase as a marker during therapy in leukemia patients.
Oxidative stress and total antioxidant status in acute leukemia at diagnosis and post remission induction phase.
[Relative deficiency of glutathione reductase and or pyruvate kinase in erythrocytes in aplastic anemia and acute leukemia]
[The glutathione enzymatic redox system in the blood of patients with lymphoproliferative diseases]
[The osmotic stability, glucose-6-phosphate dehydrogenase and glutathione reductase activity of the erythrocytes of leukemia and anemia patients]
[Use of the antioxidant complex of vitamins A, E and C in murine leukemia]
Leukemia, Lymphocytic, Chronic, B-Cell
Glutathione peroxidase, glutathione reductase, Cu-Zn superoxide dismutase activities, glutathione, nitric oxide, and malondialdehyde concentrations in serum of patients with chronic lymphocytic leukemia.
Leukemia, Myeloid, Acute
Oxidative stress and total antioxidant status in acute leukemia at diagnosis and post remission induction phase.
Liver Cirrhosis
Clinical significance of serum glutathione reductase in various clinical conditions, especially in liver diseases.
[The activity of the glutathione-dependent enzymes of erythrocytes in chronic liver diseases in children]
Liver Diseases
Antioxidant status and lipid peroxidation activity in evaluating hepatocellular damage in children.
Clinical significance of serum glutathione reductase in various clinical conditions, especially in liver diseases.
Oxidative stress and antioxidant status in patients with autoimmune liver diseases.
[On glutathione reductase in the serum of man. A contribution to the differential diagnosis of liver diseases.]
[The diagnostic importance of isocitrate dehydrogenase and of glutathione reductase in liver diseases.]
[The erythrocyte antioxidant system in chronic liver diseases]
Liver Failure
Vitamin B 1, B 2 and B 6 deficiency in neurological disorders.
Liver Neoplasms, Experimental
The activities of superoxide dismutase, catalase, glutathione peroxidase and glutathione reductase in erythrocytes of rats with experimental neoplastic disease.
Lung Diseases
Preferential effects of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) on pulmonary glutathione reductase and glutathione/glutathione disulfide ratios: possible implications for lung toxicity.
[Changes in the activity of glutathione peroxidase and glutathione reductase in the blood in nonspecific inflammatory lung diseases]
Lung Injury
Glutathione reductase targeted to type II cells does not protect mice from hyperoxic lung injury.
Oxidative stress and inflammation contribute to lung toxicity after a common breast cancer chemotherapy regimen.
Oxidative stress and lung injury induced by short-term exposure to wood smoke in guinea pigs.
Riboflavin supplementation does not attenuate hyperoxic lung injury in transgenic (spc-mt)hGR mice.
Lung Neoplasms
Determination of glutathione, glutathione reductase, glutathione peroxidase and glutathione S-transferase levels in human lung cancer tissues.
Drug-resistant human lung cancer cells are more sensitive to selenium cytotoxicity. Effects on thioredoxin reductase and glutathione reductase.
Evidence of differential cisplatin-DNA adduct formation, removal and tolerance of DNA damage in three human lung carcinoma cell lines.
Glutathione and glutathione linked enzymes in human small cell lung cancer cell lines.
Glutathione reductase (GSR) gene deletion and chromosome 8 aneuploidy in primary lung cancers detected by fluorescence in situ hybridization.
Immunohistochemical study of glutathione-related enzymes and proliferative antigens in lung cancer. Relation to cisplatin sensitivity.
In vitro effects of folic acid on gamma-glutamyltransferase and glutathione reductase activities in malignant lung and thymus tumors.
Proteomic and redox-proteomic study on the role of glutathione reductase in human lung cancer cells.
The effects of quercetin on antioxidant status and tumor markers in the lung and serum of mice treated with benzo(a)pyrene.
[Chemistry and toxicology of cigarette smoke in the lungs]
Lymphoma
Changes in glutathione-related enzymes in tumor-bearing mice after cisplatin treatment.
Mitochondrial peroxiredoxin 3 is rapidly oxidized in cells treated with isothiocyanates.
Queuine promotes antioxidant defence system by activating cellular antioxidant enzyme activities in cancer.
Lymphoma, B-Cell
Are Atlantic cod in Store Lungegårdsvann, a seawater recipient in Bergen, affected by environmental contaminants? A qRT-PCR survey.
Deficiency of dietary pyridoxine disturbed the intestinal physical barrier function of young grass carp (Ctenopharyngodon idella).
Dietary vitamin C deficiency depressed the gill physical barriers and immune barriers referring to Nrf2, apoptosis, MLCK, NF-?B and TOR signaling in grass carp (Ctenopharyngodon idella) under infection of Flavobacterium columnare.
Dietary vitamin C deficiency depresses the growth, head kidney and spleen immunity and structural integrity by regulating NF-?B, TOR, Nrf2, apoptosis and MLCK signaling in young grass carp (Ctenopharyngodon idella).
Lymphoma, Non-Hodgkin
[The glutathione enzymatic redox system in the blood of patients with lymphoproliferative diseases]
Lymphopenia
The potential of melatonin in reducing morbidity-mortality after craniocerebral trauma.
Macular Degeneration
Low glutathione reductase and peroxidase activity in age-related macular degeneration.
Magnesium Deficiency
Magnesium Deficiency and High Light Intensity Enhance Activities of Superoxide Dismutase, Ascorbate Peroxidase, and Glutathione Reductase in Bean Leaves.
Malaria
A fluoro analogue of the menadione derivative 6-[2'-(3'-methyl)-1',4'-naphthoquinolyl]hexanoic acid is a suicide substrate of glutathione reductase. Crystal structure of the alkylated human enzyme.
Antiplasmodial Activity of Nitroaromatic Compounds: Correlation with Their Reduction Potential and Inhibitory Action on Plasmodium falciparum Glutathione Reductase.
Cation exchange resins as pharmaceutical carriers for methylene blue: binding and release.
Deficiency of two red-cell flavin enzymes in a population in Sardinia: was glutathione reductase deficiency specifically selected for by malaria?
Deletion of the parasite-specific insertions and mutation of the catalytic triad in glutathione reductase from chloroquine-sensitive Plasmodium falciparum 3D7.
Facile oxidation of leucomethylene blue and dihydroflavins by artemisinins: relationship with flavoenzyme function and antimalarial mechanism of action.
Flavin analogs with antimalarial activity as glutathione reductase inhibitors.
Glutathione reductase activity and its relation with riboflavin levels measured by methemoglobin reduction by cystamine in patients with malaria (preliminary report).
Glutathione reductase and glutamate dehydrogenase of Plasmodium falciparum, the causative agent of tropical malaria.
Glutathione reductase-deficient erythrocytes as host cells of malarial parasites.
In vitro inhibition of human erythrocyte glutathione reductase by some new organic nitrates.
Is the flavin-deficient red blood cell common in Maremma, Italy, an important defense against malaria in this area?
Plasmodium falciparum glutathione reductase exhibits sequence similarities with the human host enzyme in the core structure but differs at the ligand-binding sites.
Recombinant Plasmodium falciparum glutathione reductase is inhibited by the antimalarial dye methylene blue.
Targeting the intersubunit cavity of Plasmodium falciparum glutathione reductase by a novel natural inhibitor: Computational and experimental evidence.
The 58 kDa mouse selenoprotein is a BCNU-sensitive thioredoxin reductase.
Malaria, Cerebral
Crystal structure of the antioxidant enzyme glutathione reductase inactivated by peroxynitrite.
Malnutrition
Effect of simultaneous thiamin and riboflavin deficiencies on the determination of transketolase and glutathione reductase.
Vitamin B 1, B 2 and B 6 deficiency in neurological disorders.
Mania
Protein kinase C isoforms as a target for manic-like behaviors and oxidative stress in a dopaminergic animal model of mania.
Mastocytoma
Influence of nitric oxide on the intracellular reduced glutathione pool: different cellular capacities and strategies to encounter nitric oxide-mediated stress.
Measles
Urinary riboflavin excretion and erythrocyte glutathione reductase activity in preschool children suffering from upper respiratory infections and measles.
Melanoma
Effects of 4-tertiary butyl catechol on glutathione-metabolizing enzymes in vivo and in vitro.
Glutathione and related enzymes in tumor progression and metastases of human melanoma.
Glutathione reductase-mediated thiol oxidative stress suppresses metastasis of murine melanoma cells.
Intracellular glutathione and its metabolizing enzyme activities in a metastatic variant melanoma cell line.
Opposite regulation of tyrosinase and glutathione peroxidase by intracellular thiols in human melanoma cells.
Sensitivity and resistance in human metastatic melanoma to the new chloroethylnitrosourea anti-tumor drug Fotemustine.
[Functional deficiency of riboflavin in patients with melanoma]
Melanoma, Experimental
Role of antioxidant enzymes in the induction of increased experimental metastasis by hydroxyurea.
Meningioma
Comparative analysis of antioxidative systems in malignant and benign brain tumours.
Glutathione peroxidase, glutathione reductase and protein oxidation in patients with glioblastoma multiforme and transitional meningioma.
Meningomyelocele
Comparison of erythrocyte antioxidant enzyme activities and embryologic level of neural tube defects.
Erythrocyte antioxidant enzyme activities in children with myelomeningocele.
Mercury Poisoning
The effect of experimental methyl mercury poisoning on the activity of the TPNH-specific glutathione reductase of rat brain and liver.
Methemoglobinemia
Associated red cell enzyme deficiencies and their significance in a case of congenital enzymopenic methemoglobinemia.
Methemoglobinemia and eccentrocytosis in equine erythrocyte flavin adenine dinucleotide deficiency.
Pathogenesis, laboratory diagnosis, and clinical implications of erythrocyte enzyme deficiencies in dogs, cats, and horses.
[Detection of combined forms of hemoglobino- and enzymopathies in newborns]
Migraine Disorders
Serum and intraerythrocyte antioxidant enzymes and lipid peroxides in children with migraine.
Mitochondrial Diseases
Plasma thiol status is altered in children with mitochondrial diseases.
Mitral Valve Prolapse
Imbalance in the antioxidant defense system as a possible cause of decreased compensatory and adaptive reserves in youths with mitral valve prolapse.
Mouth Neoplasms
Oxidant and antioxidant activity changes in patients with oral cancer and treated with radiotherapy.
Tobacco, antioxidant enzymes, oxidative stress, and genetic susceptibility in oral cancer.
Multiple Sclerosis
Changes in cerebrospinal fluid levels of malondialdehyde and glutathione reductase activity in multiple sclerosis.
Erythrocyte antioxidant enzymes in multiple sclerosis and the effect of hyperbaric oxygen.
Leucocyte glutathione peroxidase activity and selenium level in multiple sclerosis.
Mapping Protein Targets of Bioactive Small Molecules Using Lipid-Based Chemical Proteomics.
[Lipid peroxidation and antioxidant defence enzyme activity in multiple sclerosis]
Murine Acquired Immunodeficiency Syndrome
Liver endogenous antioxidant defenses in mice fed AIN-76A diet and infected with murine AIDS.
Muscular Dystrophies
Catalase, superoxide dismutase, glutathione reductase and thiobarbituric acid-reactive products in normal and dystrophic human muscle.
Glutathione peroxidase, glutathione reductase, and thiobarbituric acid-reactive products in muscles of chickens and mice with genetic muscular dystrophy.
[NADPH- and NADH-specific glutathione reductase (GSSGR) activity in the serum and muscles of patients with muscular dystrophy (Erb)]
[Studies on pathogenesis of muscular dystrophy: levels of thiobarbituric acid-reactive products in avian muscular dystrophy]
Muscular Dystrophy, Duchenne
Changes in some cytoplasmic enzymes from red cells fractionated into age groups by centrifugation in Ficoll/Triosil gradients. Comparison of normal humans and patients with Duchenne muscular dystrophy.
Mycoses
Antioxidative response patterns of Norway spruce bark to low-density Ceratocystis polonica inoculation
Myeloproliferative Disorders
[Superoxide dismutase activity in the platelets of myeloproliferative disorders and of hemolytic anemia with glutathione reductase deficiency (author's transl)]
Myocardial Infarction
Antioxidative defense in human myocardial reperfusion injury.
Carvedilol increases copper-zinc superoxide dismutase activity in patients with acute myocardial infarction.
Levels of glutathione reductase and glutathione peroxidase of human platelets in unstable angina and myocardial infarction.
Oleuropein offers cardioprotection in rats with acute myocardial infarction.
Sundarban Honey Confers Protection against Isoproterenol-Induced Myocardial Infarction in Wistar Rats.
The free radical system in ischemic heart disease.
[Myocardial infarction: peculiarities of lipid metabolism, oxidative and antioxidative potential]
Myocardial Ischemia
Heart protective effects and mechanism of quercetin preconditioning on anti-myocardial ischemia reperfusion (IR) injuries in rats.
SALVIANOLIC ACID B ALLEVIATING MYOCARDIUM INJURY IN ISCHEMIA REPERFUSION RATS.
Myocarditis
Concomitant exercise training attenuates the cardioprotective effects of pharmacological therapy in a murine model of acute infectious myocarditis.
[Intensity of cardiac free-radicals processes and expression of glutathione peroxidase and glutathione reductase genes in rats with adrenaline].
[Lipid peroxidation and anti-oxidative systems of an organism in experimental streptococcal myocarditis and rheumocarditis]
Myoma
Antioxidant status in women with uterine leiomyoma: relation with sex hormones.
Nasopharyngeal Carcinoma
Activities of gamma-glutamyl transpeptidase and erythrocyte glutathione dependent enzymes in nasopharyngeal carcinoma patients and normal controls.
Neoplasm Metastasis
Glutathione reductase-mediated thiol oxidative stress suppresses metastasis of murine melanoma cells.
[Activity of glutathione peroxidase (GSH-Px), glutathione reductase (GSSG-R) and superoxide dismutase (SOD-1) in single brain metastasis]
Neoplasms
1,2,3-Triazole tethered 1,2,4?trioxane trimer induces apoptosis in metastatic cancer cells and inhibits their proliferation, migration and invasion.
2-Acetylamino-3-[4-(2-acetylamino-2-carboxyethylsulfanylcarbonylamino) phenyl carbamoylsulfanyl] propionic acid, a glutathione reductase inhibitor, induces G
Acquired disturbance of erythrocyte glutathione reductase in experimental tumors.
Activities of free radical metabolizing enzymes in tumours.
Activity of Antioxidant Enzymes in the Tumor and Adjacent Noncancerous Tissues of Non-Small-Cell Lung Cancer.
Adipose Tissue Redox Microenvironment as a Potential Link between Persistent Organic Pollutants and the 16-Year Incidence of Non-hormone-Dependent Cancer.
Allicin Alleviates Dextran Sodium Sulfate- (DSS-) Induced Ulcerative Colitis in BALB/c Mice.
Alterations in lipid peroxidation and antioxidant status in different types of intracranial tumors within their relative peritumoral tissues.
Amelioration of ethanol-induced liver injury in rats by nanogold flakes.
Amelioration of tamoxifen-induced liver injury in rats by grape seed extract, black seed extract and curcumin.
Ameliorative Effect of Coenzyme Q10 and/or Candesartan on Carboplatin-Induced Nephrotoxicity: Roles of Apoptosis, Transforming Growth Factor-?1, Nuclear Factor Kappa-B And The Nrf2/HO-1 Pathway
Analgesic and anti-inflammatory activities of methanol extract from Desmodium triflorum DC in mice.
Analgesic and Anti-Inflammatory Activities of Rosa taiwanensis Nakai in Mice.
Analgesic and Anti-Inflammatory Activities of the Methanol Extract from Pogostemon cablin.
Analgesic and anti-inflammatory activities of the methanol extract of Kalanchoe gracilis (L.) DC stem in mice.
Anti-inflammation and antioxidant effect of Cordymin, a peptide purified from the medicinal mushroom Cordyceps sinensis, in middle cerebral artery occlusion-induced focal cerebral ischemia in rats.
Anti-inflammatory activity of N-(3-florophenyl)ethylcaffeamide in mice.
Anti-inflammatory effects of Scoparia dulcis L. and betulinic acid.
Anticancer effect of Limonin against benzo(a)pyrene-induced lung carcinogenesis in Swiss albino mice and the inhibition of A549 cell proliferation through apoptotic pathway.
Anticancer potentials of root extract of Polygala senega against benzo[a]pyrene-induced lung cancer in mice.
Antioxidant and antitumor efficacy of Luteolin, a dietary flavone on benzo(a)pyrene-induced experimental lung carcinogenesis.
Antioxidant and glutathione-associated enzymes in Wilms' tumour after chemotherapy.
Antioxidant enzyme levels in cases with gastrointesinal cancer.
Antioxidant status and lipid peroxidation in colorectal cancer.
Antioxidant, antiapoptotic, antigenotoxic, and hepatic ameliorative effects of L-carnitine and selenium on cadmium-induced hepatotoxicity and alterations in liver cell structure in male mice.
Antitumor activities of vanadium(IV), manganese(IV), iron(III), cobalt(II) and copper(II) complexes of 2-methylaminopyridine.
Apigenin inhibits d-galactosamine/LPS-induced liver injury through upregulation of hepatic Nrf-2 and PPAR? expressions in mice.
Apigenin protects against alcohol-induced liver injury in mice by regulating hepatic CYP2E1-mediated oxidative stress and PPAR?-mediated lipogenic gene expression.
Aqueous and Ethanol Extracts of Daylily Flower (Hemerocallis fulva L.) Protect HUVE Cells Against High Glucose.
Association Between Leukocyte Mitochondrial DNA Copy Number and Non-alcoholic Fatty Liver Disease in a Chinese Population Is Mediated by 8-Oxo-2'-Deoxyguanosine.
Benzimidazol-2-ylidene gold(I) complexes are thioredoxin reductase inhibitors with multiple antitumor properties.
Biochanin A protects against acute carbon tetrachloride-induced hepatotoxicity in rats.
Biochemical and biophysical study of chemopreventive and chemotherapeutic anti-tumor potential of some Egyptian plant extracts.
Biochemical characterization of in vivo alkylating agent resistance of a murine EMT-6 mammary carcinoma. Implication for systemic involvement in the resistance phenotype.
Biocompatibility studies of intravenously administered ionic-crosslinked chitosan-BSA nanoparticles as vehicles for antitumour drugs.
Biomarkers of oxidative stress and smoking in cancer patients.
Boeravinone B Protects Brain against Cerebral Ichemia Reperfusion Injury in Rats: Possible Role of Anti-inflammatory and Antioxidant.
Brazilian berry extract (Myrciaria jaboticaba): A promising therapy to minimize prostatic inflammation and oxidative stress.
Cardamom supplementation improves inflammatory and oxidative stress biomarkers in hyperlipidemic, overweight, and obese pre-diabetic women: a randomized double-blind clinical trial.
Changes in antioxidant defense status in response to cisplatin and 5-FU in esophageal carcinoma.
Changes in genotoxicity, inflammatory and oxidative stress parameters of workers in marble processing plants.
Characterization of drug metabolism enzymes in estrogen-induced kidney tumors in male Syrian hamsters.
Characterization of Hydrophilic Gold(I) N-Heterocyclic Carbene (NHC) Complexes as Potent TrxR Inhibitors Using Biochemical and Mass Spectrometric Approaches.
Chemomodulatory effects of Azadirachta indica on the hepatic status of skin tumor bearing mice.
Chemopreventive potential of luteolin during colon carcinogenesis induced by 1,2-dimethylhydrazine.
Chondroitin-4-sulphate reduced oxidative injury in caerulein-induced pancreatitis in mice: the involvement of NF-kappaB translocation and apoptosis activation.
Clozapine, ziprasidone, and sertindole-induced morphological changes in the rat heart and their relationship to antioxidant enzymes function.
Comparison of glutathione reductase activity and the intracellular glutathione reducing effects of 13 derivatives of 1'-acetoxychavicol acetate in Ehrlich ascites tumor cells.
Computational and Preclinical Evidence of Anti-ischemic Properties of L-Carnitine-Rich Supplement via Stimulation of Anti-inflammatory and Antioxidant Events in Testicular Torsed Rats.
Consequences of selenite supplementation on the growth and metabolism of cultures of canine mammary cells.
Constitutional trisomy 8 as first mutation in multistep carcinogenesis: clinical, cytogenetic, and molecular data on three cases.
Cytokines increase rat lung antioxidant enzymes during exposure to hyperoxia.
Depletion of brain perivascular macrophages regulates acute restraint stress-induced neuroinflammation and oxidative/nitrosative stress in rat frontal cortex.
Determination of glutathione, glutathione reductase, glutathione peroxidase and glutathione S-transferase levels in human lung cancer tissues.
Diesel exhaust exposure intensifies inflammatory and structural changes associated with lung aging in mice.
Diesel Exhaust Particles Induce Impairment of Vascular and Cardiac Homeostasis in Mice: Ameliorative Effect of Emodin.
Dietary sulphur amino acid adequacy influences glutathione synthesis and glutathione-dependent enzymes during the inflammatory response to endotoxin and tumour necrosis factor-alpha in rats.
Differences among human tumor cell lines in the expression of glutathione transferases and other glutathione-linked enzymes.
Differential sensitivity of tumor cells to externally generated hydrogen peroxide. Role of glutathione and related enzymes.
Duloxetine by Modulating the Akt/GSK3 Signaling Pathways Has Neuroprotective Effects against Methamphetamine-Induced Neurodegeneration and Cognition Impairment in Rats.
Edible Bird's Nest attenuates high fat diet-induced oxidative stress and inflammation via regulation of hepatic antioxidant and inflammatory genes.
Effect of asoka on the intracellular glutathione levels and skin tumour promotion in mice.
Effect of atorvastatin and methotrexate on solid Ehrlich tumor.
Effect of cacao liquor extract on tumor marker enzymes during chemical hepatocarcinogenesis in rats.
Effect of canagliflozin, a sodium glucose co-transporter 2 inhibitor, on cisplatin-induced nephrotoxicity in mice.
Effect of cysteamine hydrochloride supplementation on the growth performance, enterotoxic status, and glutathione turnover of broilers fed aflatoxin B1 contaminated diets.
Effect of etoricoxib on experimental oxidative testicular ischemia-reperfusion damage in rats induced with torsion-detorsion.
Effect of Ginkgo leaf parenteral solution on blood and cochlea antioxidant and immunity indexes in OM rats.
Effect of Naringenin (A naturally occurring flavanone) Against Pilocarpine-induced Status Epilepticus and Oxidative Stress in Mice.
Effect of saffron on thymocyte proliferation, intracellular glutathione levels and its antitumor activity.
Effect of tocilizumab, an interleukin-6 inhibitor, on early stage streptozotocin-induced diabetic nephropathy in rats.
Effects of dietary monocalcium phosphate supplementation on the anti-oxidative capacity, anti-bacteria function in immune organs of obscure puffer (Takifugu obscurus) after infection with Aeromonas hydrophila.
Effects of dietary monoterpene, myrcene, administration on immune- and health-related genes expression in common carp gill following exposure to copper sulfate.
Effects of inflammatory responses, apoptosis, and STAT3/NF-?B- and Nrf2-mediated oxidative stress on benign prostatic hyperplasia induced by a high-fat diet.
Effects of Occupational Silica Exposure on OXIDATIVE Stress and Immune System Parameters in Ceramic Workers in TURKEY.
Effects of the SGLT-2 Inhibitor Canagliflozin on Adenine-Induced Chronic Kidney Disease in Rats.
Embelin attenuates cisplatin-induced nephrotoxicity: Involving inhibition of oxidative stress and inflammation in addition with activation of Nrf-2/Ho-1 pathway.
Enhancement of radiation-induced oxidative stress and cytotoxicity in tumor cells by ellagic acid.
Essential oils and their constituents as anticancer agents: a mechanistic view.
Exposure to Zinc Oxide Nanoparticles Induces Neurotoxicity and Proinflammatory Response: Amelioration by Hesperidin.
Extracts from Fermented Black Garlic Exhibit a Hepatoprotective Effect on Acute Hepatic Injury.
Fe3O4@mSiO2 core-shell nanocomposite capped with disulfide gatekeepers for enzyme-sensitive controlled release of anti-cancer drugs.
Gated magnetic mesoporous silica nanoparticles for intracellular enzyme-triggered drug delivery.
Gingko Biloba protects cardiomyocytes against acute doxorubicin induced cardiotoxicity by suppressing oxidative stress.
Glutathione and glutathione linked enzymes in human small cell lung cancer cell lines.
Glutathione level and glutathione-dependent enzyme activities in blood serum of patients with gastrointestinal tract tumors.
Glutathione metabolizing enzyme activities in human thyroid.
Glutathione reductase (GSR) gene deletion and chromosome 8 aneuploidy in primary lung cancers detected by fluorescence in situ hybridization.
Glutathione reductase and lactic dehydrogenase activities of tissues of rodents with transplanted tumors.
Glutathione reductase in human and murine lung tumors: high levels of mRNA and enzymatic activity.
Glutathione reductase in human epidermal tumors. Basal and squamous cell epithelioma, verruca seborrhoeica.
Glutathione related enzymes in human testicular germ cell tumors and normal testes.
Glutathione S-transferase isoenzymes in human lung tumors.
Glutathione system in animal model of solid tumors: From regulation to therapeutic target.
Glutathione, cell proliferation, and 1,3-bis-(2-chloroethyl)-1-nitrosourea in K562 leukemia.
Glutathione-related factors are not correlated with sensitivity of human tumour cells to actinomycin D.
Graphene Oxide Normal (GO + Mn2+) and Ultrapure: Short-Term Impact on Selected Antioxidant Stress Markers and Cytokines in NHDF and A549 Cell Lines.
Greater Protective Potent of s-Methyl Cysteine and Syringic Acid Combination for NGF-differentiated PC12 Cells against Kainic acid-induced Injury.
GSH, GSH-related enzymes and GS-X pump in relation to sensitivity of human tumor cell lines to chlorambucil and adriamycin.
Hepatoprotective and antioxidant effects of gallic acid in paracetamol-induced liver damage in mice.
Homeopathic drugs Natrum sulphuricum and Carcinosin prevent azo dye-induced hepatocarcinogenesis in mice.
Human monocyte activation by cleaved form of alpha-1-antitrypsin involvement of the phagocytic pathway.
Hydrogen peroxide from cellular metabolism of cystine. A requirement for lysis of murine tumor cells by vernolepin, a glutathione-depleting antineoplastic.
Hydroxycitric acid ameliorates inflammation and oxidative stress in mouse models of multiple sclerosis.
Immunohistochemical study of glutathione-related enzymes and proliferative antigens in lung cancer. Relation to cisplatin sensitivity.
In vitro effects of folic acid on gamma-glutamyltransferase and glutathione reductase activities in malignant lung and thymus tumors.
Increase in thiol oxidative stress via glutathione reductase inhibition as a novel approach to enhance cancer sensitivity to X-ray irradiation.
Inflammatory and Antioxidant Gene Transcripts: A Novel Profile in Postoperative Atrial Fibrillation.
Influence of diet on leukocyte telomere length, markers of inflammation and oxidative stress in individuals with varied glucose tolerance: a Chinese population study.
Influence of selenium on glutathione and some associated enzymes in rats with mammary tumor induced by 7,12-dimethylbenz(a)anthracene.
Inhibition of Prostaglandin Reductase 2, a Putative Oncogene Overexpressed in Human Pancreatic Adenocarcinoma, Induces Oxidative Stress-Mediated Cell Death Involving xCT and CTH Gene Expressions through 15-Keto-PGE2.
Inhibition of thioredoxin reductase by alantolactone prompts oxidative stress-mediated apoptosis of HeLa cells.
Involvement of AMPA/kainate and GABAA receptors in topiramate neuroprotective effects against methylphenidate abuse sequels involving oxidative stress and inflammation in rat isolated hippocampus.
Isocyanates induces DNA damage, apoptosis, oxidative stress, and inflammation in cultured human lymphocytes.
Malaysian propolis, metformin and their combination, exert hepatoprotective effect in streptozotocin-induced diabetic rats.
Mechanism of inhibition of estrogen-induced renal carcinogenesis in male Syrian hamsters by vitamin C.
Mechanisms involved in the attenuation of intestinal toxicity induced by (S)-(+)-ketoprofen in re-fed rats.
Melatonin Regulates Oxidative Stress Initiated by Freund's Complete Adjuvant.
Metallothionein attenuates carmustine-induced oxidative stress and protects against pulmonary fibrosis in rats.
Metformin protects against diabetes-induced heart injury and dunning prostate cancer model.
Mitochondria-targeted chemotherapeutics: the rational design of gold(I) N-heterocyclic carbene complexes that are selectively toxic to cancer cells and target protein selenols in preference to thiols.
Modulation of antioxidant enzymes, SIRT1 and NF-?B by resveratrol and nicotinamide in alcohol-aflatoxin B1-induced hepatocellular carcinoma.
Modulation of radiation response of human tumour cells by the differentiation inducers, phenylacetate and phenylbutyrate.
Neuroprotective Effects of Forced Exercise and Bupropion on Chronic Methamphetamine-induced Cognitive Impairment via Modulation of cAMP Response Element-binding Protein/Brain-derived Neurotrophic Factor Signaling Pathway, Oxidative Stress, and Inflammatory Biomarkers in Rats.
Overweight Women with Breast Cancer on Chemotherapy Have More Unfavorable Inflammatory and Oxidative Stress Profiles.
Partial mRNA Sequences of the Biomarkers CYP1A, GST, CAT, GR, SOD, GPx, VTG and p53 in Flatfish Syacium gunteri from Gulf of Mexico.
Pequi (Caryocar brasiliense Camb.) almond oil attenuates carbon tetrachloride-induced acute hepatic injury in rats: Antioxidant and anti-inflammatory effects.
Plasma antioxidant enzymes and clastogenic factors as possible biomarkers of colorectal cancer risk.
Positive correlation between decreased cellular uptake, NADPH-glutathione reductase activity and adriamycin resistance in Ehrlich ascites tumor lines.
Potential contribution of oxidative stress and inflammation to anxiety and hypertension.
Pre-Clinical Study for the Antidiabetic Potential of Selenium Nanoparticles.
Preventive effect of silymarin-loaded chitosan nanoparticles against global cerebral ischemia/reperfusion injury in rats.
Preventive Effects of Duloxetine Against Methamphetamine Induced Neurodegeneration and Motor Activity Disorder in Rat: Possible Role of CREB/BDNF Signaling Pathway.
Progressive apoptosis in chorion laeve trophoblast cells of human fetal membrane tissues during in vitro incubation is suppressed by antioxidative reagents.
Prostaglandin reductase 2 modulates ROS-mediated cell death and tumor transformation of gastric cancer cells and is associated with higher mortality in gastric cancer patients.
Protection effect of intracellular melanin from Lachnum YM156 and Haikunshenxi capsule combination on adenine-induced chronic renal failure in mice.
Protective effect of resveratrol and vitamin E against ethanol-induced oxidative damage in mice: biochemical and immunological basis.
Protective effect of vanillic acid against benzo(a)pyrene induced lung cancer in Swiss albino mice.
Protective effects of forced exercise against topiramate-induced cognition impairment and enhancement of its antiepileptic activity: molecular and behavioral evidences.
Protective Effects of Fragaria ananassa Extract Against Cadmium Chloride-Induced Acute Renal Toxicity in Rats.
Protective role of metformin against methamphetamine induced anxiety, depression, cognition impairment and neurodegeneration in rat: The role of CREB/BDNF and Akt/GSK3 signaling pathways.
Qualitative erythrocyte enzymatic disorder in Ehrlich tumor-bearing mice.
Redox-active phytoconstituents ameliorate cell damage and inflammation in rat hippocampal neurons exposed to hyperglycemia+A?1-42 peptide.
Reduction sensitive nanocarriers mPEG-g-?-PGA/SSBPEI@siRNA for effective targeted delivery of survivin siRNA against NSCLC.
Regulation of isocyanate-induced apoptosis, oxidative stress, and inflammation in cultured human neutrophils : Isocyanate-induced neutrophils apoptosis.
Resveratrol improves sperm parameter and testicular apoptosis in cisplatin-treated rats: Effects on ERK1/2, JNK, and Akt pathways.
Role of mitogen activated protein kinases in skin tumorigenicity of patulin.
Role of pretherapeutic biomarkers in predicting postoperative radiotherapy response in patients with advanced squamous cell carcinoma.
S-Nitrosoglutathione and Hypoxia-Inducible Factor-1 Confer Chemoresistance against Carbamoylating Cytotoxicity of BCNU in Rat C6 Glioma Cells.
Selenium level and glutathione-dependent enzyme activities in normal and neoplastic human lung tissues.
Sensitivity and resistance in human metastatic melanoma to the new chloroethylnitrosourea anti-tumor drug Fotemustine.
Studies of methyl 2-nitroimidazole-1-acetohydroxamate (KIN-804) 1: effect on free radical scavenging system in mice bearing Ehrlich ascites carcinoma.
Studies on glutathione metabolism in ventral prostate and chemically induced prostatic carcinoma in rats.
Synergistic antioxidant capacities of vanillin and chitosan nanoparticles against reactive oxygen species, hepatotoxicity, and genotoxicity induced by aging in male Wistar rats.
Synthetic ?-nitrostyrene derivative CYT-Rx20 as inhibitor of oral cancer cell proliferation and tumor growth through glutathione suppression and reactive oxygen species induction.
Telomere Length, Oxidative Stress, Inflammation and BDNF Levels in Siblings of Patients with Bipolar Disorder: Implications for Accelerated Cellular Aging.
The 58 kDa mouse selenoprotein is a BCNU-sensitive thioredoxin reductase.
The activities of superoxide dismutase, catalase, glutathione peroxidase and glutathione reductase in erythrocytes of rats with experimental neoplastic disease.
The biochemistry of aging.
The decrease in antioxidant potential in human brain tumours.
The Differential Tissue Expression of Inflammatory, Oxidative Stress, and Apoptosis Markers in Human Uncontrolled Non-Heart-Beating Donors.
The effects of the Pringle maneuver on the pancreas: can octreotide be protective?
The growth performance and non-specific immunity of juvenile grass carp (Ctenopharyngodon idella) affected by dietary alginate oligosaccharide.
The histological distribution of glutathione reductase activity in solid mouse tumor transplants and a comparison with ascites tumors and normal tissues.
The organochlorine pesticide residues and antioxidant enzyme activities in human breast tumors: is there any association?
The relationship between antioxidant enzymes and bladder cancer.
The renoprotective effect of the dipeptidyl peptidase-4 inhibitor sitagliptin on adenine-induced kidney disease in rats.
The role of thioredoxin reductase and glutathione reductase in plumbagin-induced, reactive oxygen species-mediated apoptosis in cancer cell lines.
Therapeutic effectiveness of rectally administered fish oil and mesalazine in trinitrobenzenesulfonic acid-induced colitis.
Three pentacyclic triterpenes protect H9c2 cardiomyoblast cells against high-glucose-induced injury.
Trans-chalcone added in topical formulation inhibits skin inflammation and oxidative stress in a model of ultraviolet B radiation skin damage in hairless mice.
TrxR1, Gsr, and oxidative stress determine hepatocellular carcinoma malignancy.
Vitamin B 1, B 2 and B 6 deficiency in neurological disorders.
Xenobiotic metabolizing enzymes in genetically and chemically initiated mouse liver tumors.
[Activity of enzymes of glutathione metabolism and regulation by cAMP in human tumors]
[Defense system antioxidants in blood of children with neoplasms. II. Antioxidant enzymes and lipid peroxidation in erythrocytes]
[Effects of smoking and tumor process on the contents of key proteins of apoptosis and activity of antioxidant enzymes in blood].
[Glutathione reductase activity in erythrocytes of rats with transplantable Morris 5123 hepatoma]
[Glutathione reductase activity in human and animal tumors]
[Rosuvastatin and metformin decrease inflammation and oxidative stress in patients with hypertension and dyslipidemia]
[The activity of redox-regulatory systems in the primary and recurrence tumors in vulvar cancer].
[THE MODE OF CLARIFYING DIAGNOSTIC OF PROGRESSING FORMS OF OVARIAN CARCINOMA].
[Thiol-dependent protective systems in alimentary prevention of the toxic effect of carminomycin]
Nervous System Diseases
Melatonin restores neutrophil functions and prevents apoptosis amid dysfunctional glutathione redox system.
Vitamin B 1, B 2 and B 6 deficiency in neurological disorders.
Neuroblastoma
Effect of fraxetin on antioxidant defense and stress proteins in human neuroblastoma cell model of rotenone neurotoxicity. Comparative study with myricetin and N-acetylcysteine.
Electron spin resonance studies of the interaction of oxidoreductases with 2,6-dimethoxy-p-quinone and semiquinone.
Low levels of selenium compounds are selectively toxic for a human neuron cell line through ROS/RNS increase and apoptotic process activation.
The novel cholinesterase-monoamine oxidase inhibitor and antioxidant, ladostigil, confers neuroprotection in neuroblastoma cells and aged rats.
Neuroinflammatory Diseases
Selol, an organic selenium donor, prevents lipopolysaccharide-induced oxidative stress and inflammatory reaction in the rat brain.
Neuromuscular Diseases
Elevated activity of several antioxidant enzymes in neuromuscular diseases. A histochemical and biochemical study.
Non-alcoholic Fatty Liver Disease
A Decreased Response to Resistin in Mononuclear Leukocytes Contributes to Oxidative Stress in Nonalcoholic Fatty Liver Disease.
Evaluation of blood oxidative stress-related parameters in alcoholic liver disease and non-alcoholic fatty liver disease.
Obesity
Activity of antioxidant enzymes in children from families at high risk of premature coronary heart disease.
Anti-obesity Effect of Gymnema sylvestre Extract on High Fat Diet-induced Obesity in Wistar Rats.
Binge ethanol exposure increases liver injury in obese rats.
Effect of gallic acid on high fat diet-induced dyslipidaemia, hepatosteatosis and oxidative stress in rats.
Effects of acute physical exercise on oxidative stress and inflammatory status in young, sedentary obese subjects.
Phenolic compounds rutin and o-coumaric acid ameliorate obesity induced by high-fat diet in rats.
Obesity, Maternal
Altered hepatic insulin signalling in male offspring of obese mice.
Obesity, Morbid
Effects of acute physical exercise on oxidative stress and inflammatory status in young, sedentary obese subjects.
Osteoarthritis
Glutathione reductase activity correlates with concentration of extracellular matrix.
Impaired glutathione reductase activity and levels of collagenase and elastase in synovial fluid in rheumatoid arthritis.
Otitis Media with Effusion
Effect of dantrolene on lipid peroxidation, lutathione and glutathione-dependent enzyme activities in experimental otitis media with effusion in guinea pigs.
Effect of melatonin on lipid peroxidation, glutathione and glutathione-dependent enzyme activities in experimental otitis media with effusion in guinea pigs.
Overweight
B vitamins, vitamin C and hematological measurements in overweight and obese Thais in Bangkok.
Effects of acute physical exercise on oxidative stress and inflammatory status in young, sedentary obese subjects.
Overweight Women with Breast Cancer on Chemotherapy Have More Unfavorable Inflammatory and Oxidative Stress Profiles.
Peripheral Blood Mononuclear Cells Oxidative Stress and Plasma Inflammatory Biomarkers in Adults with Normal Weight, Overweight and Obesity.
Pancreatic Neoplasms
Inhibition of Prostaglandin Reductase 2, a Putative Oncogene Overexpressed in Human Pancreatic Adenocarcinoma, Induces Oxidative Stress-Mediated Cell Death Involving xCT and CTH Gene Expressions through 15-Keto-PGE2.
Inhibitors of hydroperoxide metabolism enhance ascorbate-induced cytotoxicity.
Pancreatitis
Free radical oxidation and activity of enzymes catalyzing biotransformation of xenobiotics in the liver of rats with experimental acute pancreatitis.
[Effect of quamatel on neutrophil properties, parameters of lipid peroxidation and the antioxidant defense system in blood of patients with duodenal ulcer and pancreatitis]
Pancytopenia
Hemolytic anemia and pancytopenia in glutathione reductase deficiency: further experience with riboflavin.
[Glutathione reductase and thriosephosphate isomerase deficiency in erythrocytes and thrombocytes in pancytopenia (Estren-Damashek type)]
[Pancytopenias with erythrocyte pyruvate kinase- and glutathione reductase deficiencies]
[Transient pyruvate kinase- and glutathione reductase deficiency of erythrocytes in chronic idiopathic infantile pancytopenia]
Papilloma
Pathogenesis of skin and liver neoplasms in white suckers from industrially polluted areas in Lake Ontario.
Paracoccidioidomycosis
Isoniazid acetylating phenotype in patients with paracoccidioidomycosis and its relationship with serum sulfadoxin levels, glucose-6-phosphate dehydrogenase and glutathione reductase activities.
Measurement of glucose-6-phosphate dehydrogenase and glutathione reductase activity in patients with paracoccidioidomycosis treated with ketoconazole.
Parasitemia
Changes in rodent-erythrocyte methemoglobin reductase system produced by two malaria parasites, viz. Plasmodium yoelii nigeriensis and Plasmodium berghei.
Concomitant exercise training attenuates the cardioprotective effects of pharmacological therapy in a murine model of acute infectious myocarditis.
Effect of beta-arteether treatment on erythrocytic methemoglobin reductase system in Plasmodium yoelii nigeriensis infected mice.
Glutathione reductase (EC 1.6.4.2.) in experimental trypanosomiasis.
Studies on erythrocytic methemoglobin reductase systems in Plasmodium yoelii nigeriensis infected mice.
Studies on hepatic oxidative stress and antioxidant defence systems during arteether treatment of Plasmodium yoelii nigeriensis infected mice.
Parasitic Diseases
An investigation into the riboflavin status of young Egyptians from the oasis with glucose-6-phosphate dehydrogenase deficiency.
Parkinson Disease
Free radical toxicity and antioxidants in Parkinson's disease.
Parotitis
[The participation of prostaglandin F2 in the peroxidation damages and antiperoxidation protection of the parotid gland in acute nonepidemic parotitis]
Peptic Ulcer
[Status of the glutathione system in gastroduodenal ulcers]
Periodontal Diseases
[Effect of vitamins A, E and K on the indices of the glutathione antiperoxide system in gingival tissues in periodontosis]
Periodontitis
Evaluation of Antioxidant Enzymes Activity and Malondialdehyde Levels in Chronic Periodontitis Patients with Diabetes.
phosphogluconate 2-dehydrogenase deficiency
Erythrocytic glutathione reductase, glucose-6-phosphate dehydrogenase, and 6-phosphogluconic dehydrogenase deficiencies in populations of the United States, South Vietnam, Iran, and Ethiopia.
Pneumonia
Bleomycin-induced pulmonary toxicopathological changes in rats and its prevention by walnut extract.
Comparative acute toxicity of four nickel compounds to F344 rat lung.
Polycythemia
Serum enzyme activities in patients with polycythemia and myelofibrosis. Glutamic oxaloacetic transaminase, glutamic pyruvic transaminase, lactic dehydrogenase, and glutathione reductase in serum of patients with polycythemia and myelofibrosis.
Pre-Eclampsia
Abnormal levels of antioxidant defenses in a large sample of patients with hypertensive disorders of pregnancy.
Evidence for increased methylglyoxal in the vasculature of women with preeclampsia: role in upregulation of LOX-1 and arginase.
Lipid peroxidation and antioxidant activity in complicated pregnancies.
Reduced cellular glutathione reductase activity and increased adhesion molecule expression in endothelial cells cultured with maternal plasma from women with preeclampsia.
Relationship Between Xanthine Oxidase, Ischemia Modified Albumin, Nitric Oxide with Antioxidants in Non Pregnants, Pre and Post-delivery of Normal Pregnants and Preeclampsia.
[Disbalance of redox processes in amniotic fluid at pre-eclampsia.]
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Oxidative stress and total antioxidant status in acute leukemia at diagnosis and post remission induction phase.
Primary Myelofibrosis
Glutathione reductase and nitroblue tetrazolium reduction deficiencies in neutrophils of patients with primary idiopathic myelofibrosis.
Serum enzyme activities in patients with polycythemia and myelofibrosis. Glutamic oxaloacetic transaminase, glutamic pyruvic transaminase, lactic dehydrogenase, and glutathione reductase in serum of patients with polycythemia and myelofibrosis.
Prostatic Neoplasms
Oxidative stress adaptation in aggressive prostate cancer may be counteracted by the reduction of glutathione reductase.
Subditine, a new monoterpenoid indole alkaloid from Bark of Nauclea subdita (Korth.) Steud. Induces apoptosis in human prostate cancer cells.
The effect of prostate cancer and antiandrogenic therapy on lipid peroxidation and antioxidant systems.
Protein Deficiency
Influence of protein deficiency on hexachlorocyclohexane and malathion toxicity in pregnant rats.
Oxidative stress due to nickel toxicity in the liver of protein-deficient rats.
Protective effects of zinc on oxidative stress enzymes in liver of protein deficient rats.
Protective effects of zinc on oxidative stress enzymes in liver of protein-deficient rats.
Protein-Energy Malnutrition
Glutathione and association antioxidant systems in protein energy malnutrition: results of a study in Nigeria.
Psoriasis
Aerobic Training Increased Glutathione Reductase Activity In Adults With Moderate Psoriasis: Psorexercise Study Group: 932 Board #248 June 1, 3: 30 PM - 5: 00 PM.
Analyses in blood of dermatological patients. I. Glutathione and glutathione reductase.
Deciphering psoriasis. A bioinformatic approach.
Pulmonary Disease, Chronic Obstructive
Cigarette smoke-induced induction of antioxidant enzyme activities in airway leukocytes is absent in active smokers with COPD.
Correlation of EPHX1, GSTP1, GSTM1, and GSTT1 genetic polymorphisms with antioxidative stress markers in chronic obstructive pulmonary disease.
Glutathione cycle in stable chronic obstructive pulmonary disease.
Malondialdehyde and superoxide dismutase correlate with FEV(1) in patients with COPD associated with wood smoke exposure and tobacco smoking.
Redox status of patients before cardiac surgery.
pyruvate kinase deficiency
A series of new screening procedures for pyruvate kinase deficiency, glucose-6-phosphate dehydrogenase deficiency, and glutathione reductase deficiency.
Red Blood Cell Membrane Conductance in Hereditary Haemolytic Anaemias.
Renal Insufficiency, Chronic
Erythrocyte glutathione reductase activity in chronic renal disease.
Glutathione and its associated enzymes in peripheral blood cells in different stages of chronic renal insufficiency.
Glutathione, glutathione reductase and glutathione S-transferase activities in erythrocytes and lymphocytes in chronic renal disease.
Respiratory Tract Infections
Effect of respiratory infection on tissue riboflavin and flavin enzymes in mice.
Urinary riboflavin excretion and erythrocyte glutathione reductase activity in preschool children suffering from upper respiratory infections and measles.
Retinal Degeneration
Low glutathione peroxidase in rd1 mouse retina increases oxidative stress and proteases.
Retinitis Pigmentosa
Low glutathione peroxidase in rd1 mouse retina increases oxidative stress and proteases.
Rett Syndrome
Oxidative stress in Rett syndrome.
Rheumatic Fever
[DETERMINATION OF THE DYNAMICS OF GLUTATHIONE REDUCTASE IN THE BLOOD DURING THE ACUTE PHASE OF RHEUMATIC FEVER.]
Riboflavin Deficiency
Age-related changes of glutathione content, glutathione reductase and glutathione peroxidase activity of human erythrocytes.
Alterations in dimethylnitrosamine-induced lethality and acute hepatotoxicity in rats during dietary thiamin, riboflavin and pyridoxine deficiencies.
Antioxidant enzyme levels in the erythrocytes of riboflavin-deficient and Trichinella spiralis-infected rats.
Biochemical ariboflavinosis among Nigerian rural school children.
Biochemical evaluation of the erythrocyte glutathione reductase test for riboflavin deficiency.
Depressed erythrocyte glutathione reductase activity in sickle cell disease.
Diet and vitamin nutrition of the high esophageal cancer risk population in Linxian, China.
Dietary riboflavin deficiency decreases immunity and antioxidant capacity, and changes tight junction proteins and related signaling molecules mRNA expression in the gills of young grass carp (Ctenopharyngodon idella).
Dietary Riboflavin Intake and Riboflavin Status in Young Adult Women Living in Metro Vancouver, Canada.
Effect of energy restriction on riboflavin retention in normal and deficient tissues of the rat.
Effect of riboflavin deficiency on the metabolism of the red blood cell.
Effect of riboflavin status on acetaminophen toxicity in the rat.
Effect of simultaneous thiamin and riboflavin deficiencies on the determination of transketolase and glutathione reductase.
Effects of dietary riboflavin levels on antioxidant defense of the juvenile grouper Epinephelus coioides.
Effects of moderate riboflavin deficiency on lipid metabolism in rats.
Efficacy of a riboflavin supplement given at fortnightly intervals to pregnant and lactating women in rural Gambia.
Enhanced depletion of lens reduced glutathione Adriamycin in riboflavin-deficient rats.
Enzymatic evaluation of riboflavin status of infants.
Enzymatic test for the detection of a riboflavin deficiency. NADPH-dependent glutathione reductase of red blood cells and its activation by FAD in vitro.
Impact and consequences of dietary riboflavin deficiency treatment on flesh quality loss in on-growing grass carp (Ctenopharyngodon idella).
Interaction of lead toxicity and riboflavin status in chicks (Gallus domesticus).
Intestinal immune function, antioxidant status and tight junction proteins mRNA expression in young grass carp (Ctenopharyngodon idella) fed riboflavin deficient diet.
Light (phototherapy)--induced riboflavin deficiency in the neonate.
Method for the detection of a biochemical riboflavin deficiency. Stimulation of NADPH2-dependent glutathione reductase from human erythrocytes by FAD in vitro. Investigations on the vitamin B2 status in healthly people and geriatric patients.
Morphologic, biochemical, and cytogenetic studies of bone marrow and circulating blood cells in painters exposed to ethylene glycol ethers.
Nutritional deficiencies in institutionalized mentally retarded and physically disabled individuals.
Nutritional status of rural elderly Malays: dietary and biochemical findings.
Photodegradation of riboflavin in neonates.
Protein-chemical standardization of the erythrocyte glutathione reductase activation test (EGRAC test). Application to hypothyroidism.
Riboflavin deficiency and glutathione metabolism in rats: possible mechanisms underlying altered responses to hemolytic stimuli.
Riboflavin deficiency and preeclampsia.
Riboflavin deficiency causes protein and DNA damage in HepG2 cells, triggering arrest in G1 phase of the cell cycle.
Riboflavin deficiency in women taking oral contraceptive agents.
Riboflavin deficiency, metabolic rate and brown adipose tissue function in sucking and weanling rats.
Riboflavin metabolism in the hypothyroid human adult.
Riboflavin metabolism in the hypothyroid newborn.
Riboflavin metabolism--relevance to human nutrition.
The effect of reduced dietary protein level on the activity of transketolase and glutathione reductase in pig erythrocytes.
The effect of riboflavin deficiency on white cell glutathione reductase in rats.
The influence of G-6-PD activity on the response of erythrocyte glutathione reductase to riboflavin deficiency.
The riboflavin requirement of adult dogs at maintenance is greater than previous estimates.
Update on riboflavin and multiple sclerosis: a systematic review.
Vitamin E deficiency in phrynoderma cases from Sri Lanka.
[Colorimetric method of determination of the erythrocyte glutathione reductase activity and its use in the enzymatic test for detection of riboflavin deficiency]
Rotavirus Infections
Study of oxidative-stress in rotavirus infected infant mice.
Salmonella Infections
[Early manifestations of the effect of Salmonella endotoxin on the antioxidizing enzyme systems of the liver and intestines in the rat]
Sarcoidosis
Decreased redox state in red blood cells from patients with sarcoidosis.
Sarcoma
Mapping the sheep genome: production of characterized sheep x hamster cell hybrids.
Sheep gene mapping: additional DNA markers included (CASB, CASK, LALBA, IGF-1 and AMH).
[Effect of sarcolysine on glutathione peroxidase and glutathione reductase activity in sarcoma C-45]
Schistosomiasis
Kinetic potentials of certain scavenger enzymes in fresh water snails susceptible and non-susceptible to Schistosoma infection.
Scrapie
Alteration of free radical metabolism in the brain of mice infected with scrapie agent.
Seizures
Effect of add-on melatonin on seizure outcome, neuronal damage, oxidative stress, and quality of life in generalized epilepsy with generalized onset motor seizures in adults: A randomized controlled trial.
Effect of inhibition of glutathione reductase by carmustine on central nervous system oxygen toxicity.
Effects of add-on melatonin administration on antioxidant enzymes in children with epilepsy taking carbamazepine monotherapy: a randomized, double-blind, placebo-controlled trial.
Sepsis
Therapeutic effects of simvastatin on Galectin-3 and oxidative stress parameters in endotoxemic lung tissue.
Shock, Septic
Glutathione Reductase Is Associated with the Clinical Outcome of Septic Shock in the Patients Treated Using Continuous Veno-Venous Haemofiltration.
Plasma glutathione reductase activity and prognosis of septic shock.
Sleep Initiation and Maintenance Disorders
Lipid peroxidation depends on the clock 3111T/C gene polymorphism in menopausal women with Insomnia.
Small Cell Lung Carcinoma
Glutathione and glutathione linked enzymes in human small cell lung cancer cell lines.
Starvation
Antioxidative and immunological responses in the haemolymph of wolf spider Xerolycosa nemoralis (Lycosidae) exposed to starvation and dimethoate.
Effect of starvation and insulin-induced hypoglycemia on oxidative stress scavenger system and electron transport chain complexes from rat brain, liver, and kidney.
Glutathione-Mediated Regulation of ATP Sulfurylase Activity, SO42- Uptake, and Oxidative Stress Response in Intact Canola Roots.
Metabolic responses to prolonged starvation, food restriction, and refeeding in the brown trout, Salmo trutta: oxidative stress and antioxidant defenses.
Oxidative stress and some biochemical parameters during starvation and refeeding in Astacus leptodactylus (Esch., 1823).
Relationship between hepatic glutathione content and carbon tetrachloride-induced hepatotoxicity in vivo.
Transcriptional and Proteomic Profiling of Aspergillus flavipes in Response to Sulfur Starvation.
[Glutathione defense system in various brain structures during starvation]
Status Epilepticus
Effect of Naringenin (A naturally occurring flavanone) Against Pilocarpine-induced Status Epilepticus and Oxidative Stress in Mice.
Stomach Neoplasms
Inhibition of Prostaglandin Reductase 2, a Putative Oncogene Overexpressed in Human Pancreatic Adenocarcinoma, Induces Oxidative Stress-Mediated Cell Death Involving xCT and CTH Gene Expressions through 15-Keto-PGE2.
Modulatory effect of naringenin on N-methyl-N'-nitro-N-nitrosoguanidine- and saturated sodium chloride-induced gastric carcinogenesis in male Wistar rats.
Prostaglandin reductase 2 modulates ROS-mediated cell death and tumor transformation of gastric cancer cells and is associated with higher mortality in gastric cancer patients.
[Antioxidant barrier in patients with gastric cancer--preliminary study]
Stomach Ulcer
Gastroprotective and antioxidant effects of amiodarone on indomethacin-induced gastric ulcers in rats.
Gastroprotective effect of leptin in indomethacin-induced gastric injury.
Spirulina ameliorates aspirin-induced gastric ulcer in albino mice by alleviating oxidative stress and inflammation.
Stroke
Genome-Wide Association Study of White Blood Cell Counts in Patients With Ischemic Stroke.
Oleuropein offers cardioprotection in rats with acute myocardial infarction.
Plasma oxidants and antioxidants in acute ischaemic stroke.
PON1 55/192 polymorphism, oxidative stress, type, prognosis and severity of stroke.
Relationship between estradiol and antioxidant enzymes activity of ischemic stroke.
Type 2 diabetic patients with ischemic stroke: decreased insulin sensitivity and decreases in antioxidant enzyme activity are related to different stroke subtypes.
Stroke, Lacunar
Type 2 diabetic patients with ischemic stroke: decreased insulin sensitivity and decreases in antioxidant enzyme activity are related to different stroke subtypes.
Sunburn
Photoprotection mechanism in the 'Fuji' apple peel at different levels of photooxidative sunburn.
Photoprotection mechanism in the ‘Fuji’ apple peel at different levels of photooxidative sunburn
Thrombocytopenia
Intra-erythrocytary enzymes before and after splenectomy.
Thrombophilia
Antioxidative defense enzymes in placenta protect placenta and fetus in inherited thrombophilia from hydrogen peroxide.
Thrombosis
Involvement of bioantioxidants in thrombosis in mice.
Thrombotic Stroke
Lipid peroxidation, hemolysis and antioxidant enzymes of erythrocytes in stroke.
Thymoma
Effect of prolonged phenytoin administration on rat brain gene expression assessed by DNA microarrays.
In vitro effects of folic acid on gamma-glutamyltransferase and glutathione reductase activities in malignant lung and thymus tumors.
Thymus Neoplasms
In vitro effects of folic acid on gamma-glutamyltransferase and glutathione reductase activities in malignant lung and thymus tumors.
Trypanosomiasis
Glutathione reductase (EC 1.6.4.2.) in experimental trypanosomiasis.
Tuberculosis, Meningeal
Oxidative stress and antioxidants in tubercular meningitis.
Tuberculosis, Pulmonary
The roles of glutathione, glutathione peroxidase, glutathione reductase and the carbonyl protein in pulmonary and extra pulmonary tuberculosis.
[Dynamics of the activity of antioxidant enzymes in the blood of patients with pulmonary tuberculosis]
[The oxidative metabolic indices of phagocytizing and immunocompetent cells in patients with pulmonary tuberculosis]
Urinary Bladder Neoplasms
Oxidant-antioxidant levels in patients with bladder tumours.
Uterine Cervical Neoplasms
A Novel Biological Activity of the STAT3 Inhibitor Stattic in Inhibiting Glutathione Reductase and Suppressing the Tumorigenicity of Human Cervical Cancer Cells via a ROS-Dependent Pathway.
Dynamics of proinflammatory cytokine levels and their role in the development of local and systemic effects during progressing cervical cancer.
Vascular System Injuries
Aqueous extract of Whitmania pigra Whitman ameliorates ferric chloride-induced venous thrombosis in rats via antioxidation.
Vitamin B 12 Deficiency
GLUTATHIONE REDUCTASE AND DEHYDROGENASE ACTIVITY IN VITAMIN B12 DEFICIENCY.
Vitamin E Deficiency
Effect of vitamin E deficiency on oxidative metabolism and antioxidant enzyme activity of macrophages.
Tissue and biliary glutathione disulfide in the perfused vitamin E-deficient rat liver.
Vitamin E deficiency depressed fish growth, disease resistance, and the immunity and structural integrity of immune organs in grass carp (Ctenopharyngodon idella): Referring to NF-?B, TOR and Nrf2 signaling.
[Effect of vitamin E on the oxidative metabolism of macrophages]
Vitiligo
Hermansky-Pudlak syndrome in a Swiss population.
Low catalase levels in the epidermis of patients with vitiligo.
Warts
Glutathione reductase in human epidermal tumors. Basal and squamous cell epithelioma, verruca seborrhoeica.
Xeroderma Pigmentosum
Defects in antioxidant defense and calcium transport in the epidermis of xeroderma pigmentosum patients.
Tailoring Supramolecular Prodrug Nanoassemblies for Reactive Nitrogen Species-Potentiated Chemotherapy of Liver Cancer.