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Information on EC 1.8.1.16 - glutathione amide reductase

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IUBMB Comments
A dimeric flavoprotein (FAD). The enzyme restores glutathione amide disulfide, which is produced during the reduction of peroxide by EC 1.11.1.17 (glutathione amide-dependent peroxidase), back to glutathione amide (it catalyses the reaction in the opposite direction to that shown). The enzyme belongs to the family of flavoprotein disulfide oxidoreductases, but unlike other members of the family, which are specific for NADPH, it prefers NADH .
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The expected taxonomic range for this enzyme is: Marichromatium gracile
Synonyms
GAR, garB, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2 glutathione amide + NAD+ = glutathione amide disulfide + NADH + H+
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PATHWAY SOURCE
PATHWAYS
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