Reference on EC 1.7.1.B2 - aromatic nitroreductase [NAD(P)H]
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Green, L.K.; Syddall, S.P.; Carlin, K.M.; Bell, G.D.; Guise, C.P.; Mowday, A.M.; Hay, M.P.; Smaill, J.B.; Patterson, A.V.; Ackerley, D.F.
Pseudomonas aeruginosa NfsB and nitro-CBI-DEI - a promising enzyme/prodrug combination for gene directed enzyme prodrug therapy
Mol. Cancer
12
58
2013
Escherichia coli (P38489), Pseudomonas aeruginosa (Q9HTZ9)
Bai, J.; Yang, J.; Liu, P.; Yang, Q.
Transformation pathway of 2,4,6-trinitrotoluene by Escherichia coli nitroreductases and improvement of activity using structure-based mutagenesis
Process Biochem.
50
705-711
2015
Escherichia coli (P38489)
Van Hung Le, V.; Davies, I.; Moon, C.; Wheeler, D.; Biggs, P.; Rakonjac, J.
Novel 5-nitrofuran-activating reductase in Escherichia coli
Antimicrob. Agents Chemother.
63
e00868-19
2019
Escherichia coli
Toogood, H.; Scrutton, N.
Flavin oxidation state impacts on nitrofuran antibiotic binding orientation in nitroreductases
Biochem. J.
478
3423-3428
2021
Escherichia coli
Williams, E.M.; Rich, M.H.; Mowday, A.M.; Ashoorzadeh, A.; Copp, J.N.; Guise, C.P.; Anderson, R.F.; Flanagan, J.U.; Smaill, J.B.; Patterson, A.V.; Ackerley, D.F.
Engineering Escherichia coli NfsB To activate a hypoxia-resistant analogue of the PET probe EF5 to enable non-invasive imaging during enzyme prodrug therapy
Biochemistry
58
3700-3710
2019
Escherichia coli (P38489), Escherichia coli
Hyde, E.; Chau, A.; Smith, L.
Backbone assignment of E. coli NfsB and the effects of addition of the cofactor analogue nicotinic acid
Biomol. NMR Assign.
15
143-151
2021
Escherichia coli
Williams, E.; Sharrock, A.; Rylott, E.; Bruce, N.; MacKichan, J.; Ackerley, D.
A cofactor consumption screen identifies promising NfsB family nitroreductases for dinitrotoluene remediation
Biotechnol. Lett.
41
1155-1162
2019
Bacillus subtilis (O34475), Vibrio vulnificus (Q7MCD2), Vibrio vulnificus ATCC 27562 (Q7MCD2), Bacillus subtilis 168 (O34475)
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