Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

Reference on EC 1.7.1.7 - GMP reductase

Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Moffat, K.G.; Mackinnon, G.
Cloning of the Escherichia coli K-12 guaC gene following its transposition into the RP4:Mu cointegrate
Gene
40
141-143
1985
Escherichia coli
Manually annotated by BRENDA team
Stephens, R.W.; Whittaker, V.K.
Calf thymus GMP reductase: control by XMP
Biochem. Biophys. Res. Commun.
53
975-981
1973
Bos taurus
Manually annotated by BRENDA team
Endo, T.; Uratani, B.; Freese, E.
Purine salvage pathways of Bacillus subtilis and effect of guanine on growth of GMP reductase mutants
J. Bacteriol.
155
169-179
1983
Bacillus subtilis
Manually annotated by BRENDA team
Andrews, S.C.; Guest, J.R.
Nucleotide sequence of the gene encoding the GMP reductase of Escherichia coli K12
Biochem. J.
255
35-43
1988
Escherichia coli
Manually annotated by BRENDA team
Spector, T.; Jones, T.E.
Guanosine 5-monophosphate reductase from Leishmania donovani. A possible chemotherapeutic target
Biochem. Pharmacol.
31
3891-3897
1982
Leishmania donovani
Manually annotated by BRENDA team
Neuhard, J.; Nygaard, P.
Escherichia coli and Salmonella typhimurium cellular and molecular biology
American Society for Microbiology Washington (Neidhardt, F. C. , Ingraham, J. L. , Low, K. B. , Magasanik, B. , Schaechter, M. , Umbarger, E. , eds. )
1
445-473
1987
Salmonella enterica subsp. enterica serovar Typhimurium
-
Manually annotated by BRENDA team
Garber, B.B.; Jochimsen, B.U.; Gots, J.S.
Glutamine and related analogs regulate guanosine monophosphate reductase in Salmonella typhimurium
J. Bacteriol.
143
105-111
1980
Salmonella enterica subsp. enterica serovar Typhimurium
Manually annotated by BRENDA team
Mitchell, A.; Sin, I.L.; Finch, L.R.
Enzymes of purine metabolism in Mycoplasma mycoides subsp. mycoides
J. Bacteriol.
134
706-712
1978
Mycoplasma mycoides
Manually annotated by BRENDA team
Spector, T.; Jones, T.E.; Miller, R.L.
Reaction mechanism and specificity of human GMP reductase. Substrates, inhibitors, activators, and inactivators
J. Biol. Chem.
254
2308-2315
1979
Homo sapiens
Manually annotated by BRENDA team
Renart, M.F.; Renart, J.; Sillero, M.A.G.; Sillero, A.
Guanosine monophosphate reductase from Artemia salina: Inhibition by xanthosine monophosphate and activation by diguanosine tetraphosphate
Biochemistry
15
4962-4966
1976
Artemia salina
Manually annotated by BRENDA team
Renart, M.F.; Sillero, A.
GMP reductase in Artemia salina
Biochim. Biophys. Acta
341
178-186
1974
Artemia salina
Manually annotated by BRENDA team
Mackenzie, J.J.; Sorensen, L.B.
Guanosine 5-phosphate reductase of human erythrocytes
Biochim. Biophys. Acta
327
282-294
1973
Homo sapiens
Manually annotated by BRENDA team
Brox, L.W.; Hampton, A.
Inactivation of guanosine 5-phosphate reductase by 6-chloro-, 6-mercapto-, and 2-amino-6-mercapto-9-beta-D-ribofuranosylpurine 5-phosphates
Biochemistry
7
398-405
1968
Klebsiella aerogenes
Manually annotated by BRENDA team
Mager, J.; Magasanik, B.
Guanosine 5'-phosphate reductase and its role in the interconversion of purine nucleotides
J. Biol. Chem.
235
1474-1478
1960
Klebsiella aerogenes, Escherichia coli, Salmonella enterica subsp. enterica serovar Typhimurium
Manually annotated by BRENDA team
Salvatore, D.; Bartha, T.; Larsen, P.R.
The guanosine monophosphate reductase gene is conserved in rats and its expression increases rapidly in brown adipose tissue during cold exposure
J. Biol. Chem.
273
31092-31096
1998
Rattus norvegicus (Q9Z244)
Manually annotated by BRENDA team
Deng, Y.; Wang, Z.; Ying, K.; Gu, S.; Ji, C.; Huang, Y.; Gu, X.; Wang, Y.; Xu, Y.; Li, Y.; Xie, Y.; Mao, Y.
NADPH-dependent GMP reductase isoenzyme of human (GMPR2). Expression, purification, and kinetic properties
Int. J. Biochem. Cell Biol.
34
1035-1050
2002
Homo sapiens, Homo sapiens (Q9P2T1), no activity in Haemophilus influenzae, no activity in Methanocaldococcus jannaschii, no activity in Mycoplasma genitalium
Manually annotated by BRENDA team
Ji, C.N.; Ying, G.; Deng, Y.F.; Chen, S.; Zhang, W.H.; Shu, G.; Xie, Y.; Mao, Y.M.
Purification, crystallization and preliminary X-ray studies of GMP reductase 2 from human
Acta Crystallogr. Sect. D
59
1109-1110
2003
Homo sapiens
Manually annotated by BRENDA team
Zhang, J.; Zhang, W.; Zou, D.; Chen, G.; Wan, T.; Zhang, M.; Cao, X.
Cloning and functional characterization of GMPR2, a novel human guanosine monophosphate reductase, which promotes the monocytic differentiation of HL-60 leukemia cells
J. Cancer Res. Clin. Oncol.
129
76-83
2003
Homo sapiens (Q9P2T1), Homo sapiens
Manually annotated by BRENDA team
Mohamed Fahmy Gad El-Rab, S.; Abdel-Fattah Shoreit, A.; Fukumori, Y.
Effects of cadmium stress on growth, morphology, and protein expression in Rhodobacter capsulatus B10
Biosci. Biotechnol. Biochem.
70
2394-2402
2006
Rhodobacter capsulatus, Rhodobacter capsulatus B10
Manually annotated by BRENDA team
Li, J.; Wei, Z.; Zheng, M.; Gu, X.; Deng, Y.; Qiu, R.; Chen, F.; Ji, C.; Gong, W.; Xie, Y.; Mao, Y.
Crystal structure of human guanosine monophosphate reductase 2 (GMPR2) in complex with GMP
J. Mol. Biol.
355
980-988
2006
Homo sapiens
Manually annotated by BRENDA team
Martinelli, L.K.; Ducati, R.G.; Rosado, L.A.; Breda, A.; Selbach, B.P.; Santos, D.S.; Basso, L.A.
Recombinant Escherichia coli GMP reductase: kinetic, catalytic and chemical mechanisms, and thermodynamics of enzyme-ligand binary complex formation
Mol. Biosyst.
7
1289-1305
2011
Escherichia coli
Manually annotated by BRENDA team
Wawrzyniak, J.A.; Bianchi-Smiraglia, A.; Bshara, W.; Mannava, S.; Ackroyd, J.; Bagati, A.; Omilian, A.R.; Im, M.; Fedtsova, N.; Miecznikowski, J.C.; Moparthy, K.C.; Zucker, S.N.; Zhu, Q.; Kozlova, N.I.; Berman, A.E.; Hoek, K.S.; Gudkov, A.V.; Shewach, D.S.; Morrison, C.D.; Nikiforov, M.A.
A purine nucleotide biosynthesis enzyme guanosine monophosphate reductase is a suppressor of melanoma invasion
Cell Rep.
5
493-507
2013
Homo sapiens (P36959), Homo sapiens
Manually annotated by BRENDA team
Rosenberg, M.M.; Redfield, A.G.; Roberts, M.F.; Hedstrom, L.
Substrate and Cofactor Dynamics on Guanosine Monophosphate Reductase Probed by High Resolution Field Cycling 31P NMR Relaxometry
J. Biol. Chem.
291
22988-22998
2016
Homo sapiens (Q9P2T1)
Manually annotated by BRENDA team
Smith, S.; Boitz, J.; Chidambaram, E.S.; Chatterjee, A.; Ait-Tihyaty, M.; Ullman, B.; Jardim, A.
The cystathionine-beta-synthase domains on the guanosine 5'-monophosphate reductase and inosine 5'-monophosphate dehydrogenase enzymes from Leishmania regulate enzymatic activity in response to guanylate and adenylate nucleotide levels
Mol. Microbiol.
100
824-840
2016
Leishmania major (Q4QEB3)
Manually annotated by BRENDA team
Sarwono, A.E.Y.; Suganuma, K.; Mitsuhashi, S.; Okada, T.; Musinguzi, S.P.; Shigetomi, K.; Inoue, N.; Ubukata, M.
Identification and characterization of guanosine 5'-monophosphate reductase of Trypanosoma congolense as a drug target
Parasitol. Int.
66
537-544
2017
Trypanosoma congolense (G0UMT0), Trypanosoma congolense, Trypanosoma congolense IL3000 (G0UMT0)
Manually annotated by BRENDA team
Bessho, T.; Okada, T.; Kimura, C.; Shinohara, T.; Tomiyama, A.; Imamura, A.; Kuwamura, M.; Nishimura, K.; Fujimori, K.; Shuto, S.; Ishibashi, O.; Kubata, B.K.; Inui, T.
Novel characteristics of Trypanosoma brucei guanosine 5-monophosphate reductase distinct from host animals
PLoS Negl. Trop. Dis.
10
e0004339
2016
Homo sapiens (P36959), Homo sapiens (Q9P2T1), Trypanosoma brucei brucei (Q57ZS7), Trypanosoma brucei brucei 927/4 GUTat10.1 (Q57ZS7)
Manually annotated by BRENDA team
Rosenberg, M.M.; Redfield, A.G.; Roberts, M.F.; Hedstrom, L.
Dynamic characteristics of guanosine-5'-monophosphate reductase complexes revealed by high-resolution 31P field-cycling NMR relaxometry
Biochemistry
57
3146-3154
2018
Homo sapiens (Q9P2T1)
Manually annotated by BRENDA team
Sommerville, E.W.; Dalla Rosa, I.; Rosenberg, M.M.; Bruni, F.; Thompson, K.; Rocha, M.; Blakely, E.L.; He, L.; Falkous, G.; Schaefer, A.M.; Yu-Wai-Man, P.; Chinnery, P.F.; Hedstrom, L.; Spinazzola, A.; Taylor, R.W.; Gorman, G.S.
Identification of a novel heterozygous guanosine monophosphate reductase (GMPR) variant in a patient with a late-onset disorder of mitochondrial DNA maintenance
Clin. Genet.
97
276-286
2020
Homo sapiens (P36959)
Manually annotated by BRENDA team
Bairagya, H.R.; Tasneem, A.; Rai, G.P.; Reyaz, S.
Structural and dynamical impact of water molecules at substrate- or product-binding sites in human GMPR enzyme A study by molecular dynamics simulations
J. Phys. Chem. B
125
1351-1362
2021
Homo sapiens (P36959), Homo sapiens (Q9P2T1), Homo sapiens
Manually annotated by BRENDA team
Imamura, A.; Okada, T.; Mase, H.; Otani, T.; Kobayashi, T.; Tamura, M.; Kubata, B.K.; Inoue, K.; Rambo, R.P.; Uchiyama, S.; Ishii, K.; Nishimura, S.; Inui, T.
Allosteric regulation accompanied by oligomeric state changes of Trypanosoma brucei GMP reductase through cystathionine-beta-synthase domain
Nat. Commun.
11
1837
2020
Trypanosoma brucei, Trypanosoma brucei ILTat
Manually annotated by BRENDA team