Disease on EC 1.6.5.10 - NADPH dehydrogenase (quinone)
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Abscess
Adaptive immune defects against glycoantigens in chronic granulomatous disease via dysregulated nitric oxide production.
Acidosis
Possible mechanism(s) of arachidonic acid-induced intracellular acidosis in rat cardiac myocytes.
Acute Coronary Syndrome
Is there a clinical role for oxidative stress biomarkers in atherosclerotic diseases?
Acute Kidney Injury
CYBA Gene Polymorphisms and Adverse Outcomes in Acute Kidney Injury: A Prospective Cohort Study.
Acute Kidney Injury
Farnesoid X receptor agonist obeticholic acid inhibits renal inflammation and oxidative stress during lipopolysaccharide-induced acute kidney injury.
Acute Kidney Injury
Hyperbaric oxygen preconditioning and the role of NADPH oxidase inhibition in postischemic acute kidney injury induced in spontaneously hypertensive rats.
Acute Kidney Injury
NADPH oxidase p22phox and catalase gene variants are associated with biomarkers of oxidative stress and adverse outcomes in acute renal failure.
Acute Kidney Injury
Short chain fatty acid, acetate ameliorates sepsis-induced acute kidney injury by inhibition of NADPH oxidase signaling in T cells.
Acute Kidney Injury
TGF-?-mediated NADPH oxidase 4-dependent oxidative stress promotes colistin-induced acute kidney injury.
Acute Lung Injury
Acetovanillone prevents cyclophosphamide-induced acute lung injury by modulating PI3K/Akt/mTOR and Nrf2 signaling in rats.
Acute Lung Injury
Acute lung injury leads to depression-like symptoms through upregulation of neutrophilic and neuronal NADPH oxidase signaling in a murine model.
Acute Lung Injury
Apocynin alleviates lung injury by suppressing NLRP3 inflammasome activation and NF-?B signaling in acute pancreatitis.
Acute Lung Injury
Effect of the NADPH oxidase inhibitor apocynin on septic lung injury in guinea pigs.
Acute Lung Injury
In Vivo evidence of free radical generation in the mouse lung after exposure to Pseudomonas Aeruginosa bacterium: An ESR spin-trapping investigation.
Acute Lung Injury
In vivo lipid-derived free radical formation by NADPH oxidase in acute lung injury induced by lipopolysaccharide: a model for ARDS.
Acute Lung Injury
Inhibition of NADPH oxidase prevents acute lung injury in obese rats following severe trauma.
Acute Lung Injury
Inhibition of spleen tyrosine kinase signaling protects against acute lung injury through blockade of NADPH oxidase and IL-17A in neutrophils and ?? T cells respectively in mice.
Acute Lung Injury
NADPH oxidase and Nrf2 regulate gastric aspiration-induced inflammation and acute lung injury.
Acute Lung Injury
Pivotal Role of Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 in Inflammatory Pulmonary Diseases.
Acute Lung Injury
Propofol alleviates acute lung injury following orthotopic autologous liver transplantation in rats via inhibition of the NADPH oxidase pathway.
Acute Lung Injury
Protection against LPS-induced acute lung injury by a mechanism-based inhibitor of NADPH oxidase (type 2).
Acute Lung Injury
Protective effects of diphenyleneiodonium, an NADPH oxidase inhibitor, on lipopolysaccharide-induced acute lung injury.
Adenocarcinoma
Acid-induced p16 hypermethylation contributes to development of esophageal adenocarcinoma via activation of NADPH oxidase NOX5-S.
Adenocarcinoma
Apocynin, an NADPH oxidase inhibitor, suppresses rat prostate carcinogenesis.
Adenocarcinoma
Bile acid receptor TGR5, NADPH Oxidase NOX5-S and CREB Mediate Bile Acid-Induced DNA Damage In Barrett's Esophageal Adenocarcinoma Cells.
Adenocarcinoma
Bile acid reflux contributes to development of esophageal adenocarcinoma via activation of phosphatidylinositol-specific phospholipase Cgamma2 and NADPH oxidase NOX5-S.
Adenocarcinoma
cAMP-response element-binding protein mediates acid-induced NADPH oxidase NOX5-S expression in Barrett esophageal adenocarcinoma cells.
Adenocarcinoma
Decreased NADPH oxidase expression and antioxidant activity in cachectic skeletal muscle.
Adenocarcinoma
Extracellular matrix stimulates reactive oxygen species production and increases pancreatic cancer cell survival through 5-lipoxygenase and NADPH oxidase.
Adenocarcinoma
NADPH Oxidase Activation in Pancreatic Cancer Cells Is Mediated through Akt-dependent Up-regulation of p22phox.
Adenocarcinoma
NADPH Oxidase NOX5-S and NF-?B1 Mediate Acid-Induced Microsomal Prostaglandin Synthase-1 (Mpges1) Expression in Barrett's Esophageal Adenocarcinoma (EA) Cells.
Adenocarcinoma
NADPH oxidase NOX5-S mediates acid-induced cyclooxygenase-2 expression via activation of NF-kappaB in Barrett's esophageal adenocarcinoma cells.
Adenocarcinoma
Rho Kinase ROCK2 Mediates Acid-Induced NADPH Oxidase NOX5-S Expression in Human Esophageal Adenocarcinoma Cells.
Adenocarcinoma
Role Of Intracellular Calcium And NADPH Oxidase NOX5-S In Acid-Induced DNA Damage In Barrett's cells and Barrett's Esophageal Adenocarcinoma Cells.
Adenocarcinoma
Role of Rac1 in regulation of NOX5-S function in Barrett's esophageal adenocarcinoma cells.
Adenocarcinoma
STAT5 mediates PAF-induced NADPH oxidase NOX5-S expression in Barrett's esophageal adenocarcinoma cells.
Adenocarcinoma of Lung
HIF-1alpha signaling is augmented during intermittent hypoxia by induction of the Nrf2 pathway in NOX1-expressing adenocarcinoma A549 cells.
Adenoma, Pleomorphic
Binding of pleomorphic adenoma gene-like 2 to the tumor necrosis factor (TNF)-alpha-responsive region of the NCF2 promoter regulates p67(phox) expression and NADPH oxidase activity.
Adenomyosis
Involvement of NADPH oxidase and NF-?B activation in CXCL1 induction by vascular endothelial growth factor in human endometrial epithelial cells of patients with adenomyosis.
Adrenoleukodystrophy
Oxidative imbalance in nonstimulated X-adrenoleukodystrophy-derived lymphoblasts.
Aggressive Periodontitis
NADPH oxidase (CYBA) and FcgammaR polymorphisms as risk factors for aggressive periodontitis: a case-control association study.
Aggressive Periodontitis
Respiratory burst of neutrophils in diabetic patients with periodontal disease.
Agranulocytosis
Involvement of Myeloperoxidase and NADPH Oxidase in the Covalent Binding of Amodiaquine and Clozapine to Neutrophils: Implications for Drug-Induced Agranulocytosis.
AIDS Dementia Complex
Cooperative induction of CXCL10 involves NADPH oxidase: Implications for HIV dementia.
Albuminuria
A Salt-Induced Reno-Cerebral Reflex Activates Renin-Angiotensin Systems and Promotes CKD Progression.
Albuminuria
Accumulation of advanced oxidation protein products induces podocyte apoptosis and deletion through NADPH-dependent mechanisms.
Albuminuria
Advanced oxidation protein products decrease expression of nephrin and podocin in podocytes via ROS-dependent activation of p38 MAPK.
Albuminuria
Albuminuria, expression of nicotinamide adenine dinucleotide phosphate oxidase and monocyte chemoattractant protein-1 in the renal tubules of hypertensive Dahl salt-sensitive rats.
Albuminuria
Apocynin attenuates tubular apoptosis and tubulointerstitial fibrosis in transgenic mice independent of hypertension.
Albuminuria
Attenuation of NADPH oxidase activation and glomerular filtration barrier remodeling with statin treatment.
Albuminuria
Calcium channel blocker enhances beneficial effects of an angiotensin II AT1 receptor blocker against cerebrovascular-renal injury in type 2 diabetic mice.
Albuminuria
Candesartan reduced advanced glycation end-products accumulation and diminished nitro-oxidative stress in type 2 diabetic KK/Ta mice.
Albuminuria
Cardiac myocyte-derived follistatin-like 1 prevents renal injury in a subtotal nephrectomy model.
Albuminuria
Diabetes-Induced Reactive Oxygen Species: Mechanism of Their Generation and Role in Renal Injury.
Albuminuria
Exacerbation of albuminuria and renal fibrosis in subtotal renal ablation model of adiponectin-knockout mice.
Albuminuria
Hypoglycaemic, antioxidative and nephroprotective effects of taurine in alloxan diabetic rabbits.
Albuminuria
Mechanisms of podocyte injury in diabetes: role of cytochrome P450 and NADPH oxidases.
Albuminuria
NADPH oxidase-mediated triggering of inflammasome activation in mouse podocytes and glomeruli during hyperhomocysteinemia.
Albuminuria
RAGE-Aptamer Blocks the Development and Progression of Experimental Diabetic Nephropathy.
Albuminuria
Selective albuminuria via podocyte albumin transport in puromycin nephrotic rats is attenuated by an inhibitor of NADPH oxidase.
Albuminuria
The mTOR promotes oxidative stress-induced apoptosis of mesangial cells in diabetic nephropathy.
Albuminuria
Theobromine increases NAD?/Sirt-1 activity and protects the kidney under diabetic conditions.
Alkalosis
Extracellular alkalosis activates ERK mitogen-activated protein kinase of vascular smooth muscle cells through NADPH-mediated formation of reactive oxygen species.
Alveolar Bone Loss
Effect of resveratrol on the progression of experimental periodontitis in an ovariectomized rat model of osteoporosis: Morphometric, immune-enzymatic, and gene expression analysis.
Alveolitis, Extrinsic Allergic
Role of NADPH oxidase in host defense against aspergillosis.
Alzheimer Disease
AGEs Induce Cell Death via Oxidative and Endoplasmic Reticulum Stresses in Both Human SH-SY5Y Neuroblastoma Cells and Rat Cortical Neurons.
Alzheimer Disease
Amino- and carboxyl-terminal mutants of presenilin 1 cause neuronal cell death through distinct toxic mechanisms: Study of 27 different presenilin 1 mutants.
Alzheimer Disease
Amyloid ? induces microglia to phagocytose neurons via activation of protein kinase Cs and NADPH oxidase.
Alzheimer Disease
Apocynin administration does not improve behavioral and neuropathological deficits in a transgenic mouse model of Alzheimer's disease.
Alzheimer Disease
Astragaloside IV ameliorates cognitive impairment and neuroinflammation in an oligomeric A? induced Alzheimer's disease mouse model via inhibition of microglial activation and NADPH oxidase expression.
Alzheimer Disease
beta-amyloid activates the O-2 forming NADPH oxidase in microglia, monocytes, and neutrophils. A possible inflammatory mechanism of neuronal damage in Alzheimer's disease.
Alzheimer Disease
Brain Perivascular Macrophages Initiate the Neurovascular Dysfunction of Alzheimer A? Peptides.
Alzheimer Disease
Chronic apocynin treatment attenuates beta amyloid plaque size and microglial number in hAPP(751)(SL) mice.
Alzheimer Disease
Cognitive enhancing effect of diapocynin in D-galactose-ovariectomy-induced Alzheimer's-like disease in rats: Role of ERK, GSK-3?, and JNK signaling.
Alzheimer Disease
Design of dual inhibitors of ROCK-I and NOX2 as potential leads for the treatment of neuroinflammation associated with various neurological diseases including autism spectrum disorder.
Alzheimer Disease
Motor coordination and synaptic plasticity deficits are associated with increased cerebellar activity of NADPH oxidase, CAMKII, and PKC at preplaque stage in the TgCRND8 mouse model of Alzheimer's disease.
Alzheimer Disease
Neurodegenerative Disease: Roles for Sex, Hormones, and Oxidative Stress.
Alzheimer Disease
Neurovascular coupling in the normal brain and in hypertension, stroke, and Alzheimer disease.
Alzheimer Disease
Oligomeric A?-induced microglial activation is possibly mediated by NADPH oxidase.
Alzheimer Disease
Oxidative Stress, Neuroinflammation, and NADPH Oxidase: Implications in the Pathogenesis and Treatment of Alzheimer's Disease.
Alzheimer Disease
The microglial NADPH oxidase complex as a source of oxidative stress in Alzheimer's disease.
Alzheimer Disease
The role of secretory phospholipase A2 in the central nervous system and neurological diseases.
Alzheimer Disease
The roles of NADPH oxidase and phospholipases A2 in oxidative and inflammatory responses in neurodegenerative diseases.
Amyotrophic Lateral Sclerosis
The inflammatory NADPH oxidase enzyme modulates motor neuron degeneration in amyotrophic lateral sclerosis mice.
Amyotrophic Lateral Sclerosis
The NADPH oxidase pathway is dysregulated by the P2X7 receptor in the SOD1-G93A microglia model of amyotrophic lateral sclerosis.
Anaplasmosis
Commentary: adaptive immunity in the absence of innate immune responses? The un-Tolled truth of the silent invaders.
Androgen-Insensitivity Syndrome
A2A AR deficiency leads to impaired tracheal relaxation via NADPH oxidase pathway in allergic mice.
Anemia
Sumoylation of nucleoprotein (NP) mediated by activation of NADPH oxidase complex is a consequence of oxidative cellular stress during infection by Infectious salmon anemia (ISA) virus necessary to viral progeny.
Anemia, Sickle Cell
Endothelin-1 Contributes to the Progression of Renal Injury in Sickle Cell Disease via Reactive Oxygen Species.
Anemia, Sickle Cell
Erythrocyte NADPH oxidase activity modulated by Rac GTPases, PKC, and plasma cytokines contributes to oxidative stress in sickle cell disease.
Anemia, Sickle Cell
Modulation of redox pathways in neutrophils from sickle cell disease patients.
Anemia, Sickle Cell
Raised neutrophil phospholipase A2 activity and defective priming of NADPH oxidase and phospholipase A2 in sickle cell disease.
Anemia, Sickle Cell
Up-regulation of NADPH oxidase components and increased production of interferon-gamma by leukocytes from sickle cell disease patients.
Aneurysm
Anatomically specific reactive oxygen species production participates in Marfan syndrome aneurysm formation.
Aneurysm
Inhibition of reactive oxygen species attenuates aneurysm formation in a murine model.
Aneurysm
Mechanisms of oxidative stress in human aortic aneurysms - Association with clinical risk factors for atherosclerosis and disease severity.
Angina Pectoris
Suppressing NADPH oxidase-dependent oxidative stress in the vasculature with nitric oxide donors.
Antiphospholipid Syndrome
NCF1-339 polymorphism is associated with altered formation of neutrophil extracellular traps, high serum interferon activity and antiphospholipid syndrome in systemic lupus erythematosus.
Aortic Aneurysm
Redox stress in Marfan syndrome: Dissecting the role of the NADPH oxidase NOX4 in aortic aneurysm.
Aortic Aneurysm
The protective effect of puerarin on angiotensin II-induced aortic aneurysm formation by the inhibition of NADPH oxidase activation and oxidative stress-triggered AP-1 signaling pathways.
Aortic Aneurysm, Abdominal
Deletion of p47phox attenuates angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E-deficient mice.
Aortic Aneurysm, Abdominal
NADPH oxidase deficiency exacerbates angiotensin II-induced abdominal aortic aneurysms in mice.
Aortic Aneurysm, Abdominal
Vitamin E inhibits abdominal aortic aneurysm formation in angiotensin II-infused apolipoprotein E-deficient mice.
Aortic Aneurysm, Thoracic
Pleiotropic effects of ARB in vascular metabolism--focusing on atherosclerosis-based cardiovascular disease.
Aortic Coarctation
Effects of aortic coarctation on aortic antioxidant enzymes and NADPH oxidase protein expression.
Arteriovenous Fistula
p47phox-dependent NADPH oxidase regulates flow-induced vascular remodeling.
Arthritis
Advanced intercross line mapping suggests that ncf1 (ean6) regulates severity in an animal model of guillain-barre syndrome.
Arthritis
Arthritis suppression by NADPH activation operates through an interferon-beta pathway.
Arthritis
Deficiency of NADPH oxidase components p47phox and gp91phox caused granulomatous synovitis and increased connective tissue destruction in experimental arthritis models.
Arthritis
Inconsistent susceptibility to autoimmunity in inbred LEW rats is due to genetic crossbreeding involving segregation of the arthritis-regulating gene Ncf1.
Arthritis
Increased ILC3s associated with higher levels of IL-1? aggravates inflammatory arthritis in mice lacking phagocytic NADPH oxidase.
Arthritis
Lack of reactive oxygen species breaks T cell tolerance to collagen type II and allows development of arthritis in mice.
Arthritis
Modulation of inflammatory arthritis by inhibition of poly(ADP ribose) polymerase.
Arthritis
Monocyte-Derived Dendritic Cell Differentiation in Inflammatory Arthritis Is Regulated by the JAK/STAT Axis via NADPH Oxidase Regulation.
Arthritis
Positional identification of Ncf1 as a gene that regulates arthritis severity in rats.
Arthritis
Reactive Oxygen Species Regulate Innate But Not Adaptive Inflammation in ZAP70-Mutated SKG Arthritic Mice.
Arthritis
Rheumatoid arthritis: the role of reactive oxygen species in disease development and therapeutic strategies.
Arthritis
Suppression of inflammatory arthritis by simultaneous inhibition of nitric oxide synthase and NADPH oxidase.
Arthritis, Experimental
Synergistic effects of thalidomide and poly (ADP-ribose) polymerase inhibition on type II collagen-induced arthritis in mice.
Arthritis, Rheumatoid
Activation of neutrophil reactive-oxidant production by synovial fluid from patients with inflammatory joint disease. Soluble and insoluble immunoglobulin aggregates activate different pathways in primed and unprimed cells.
Arthritis, Rheumatoid
Bb2Bb3 regulation of murine Lyme arthritis is distinct from Ncf1 and independent of the phagocyte nicotinamide adenine dinucleotide phosphate oxidase.
Arthritis, Rheumatoid
Hydrogen Peroxide As an Immunological Transmitter Regulating Autoreactive T Cells.
Arthritis, Rheumatoid
Hydroxytyrosol promotes autophagy by regulating SIRT1 against advanced oxidation protein product?induced NADPH oxidase and inflammatory response.
Arthritis, Rheumatoid
NADPH oxidase priming and p47phox phosphorylation in neutrophils from synovial fluid of patients with rheumatoid arthritis and spondylarthropathy.
Arthritis, Rheumatoid
Superoxide production and NADPH oxidase expression in human rheumatoid synovial cells: regulation by interleukin-1beta and tumour necrosis factor-alpha.
Aspergillosis
Corticosteroids block autophagy protein recruitment in Aspergillus fumigatus phagosomes via targeting dectin-1/Syk kinase signaling.
Aspergillosis
Mitochondrial Reactive Oxygen Species Enhance Alveolar Macrophage Activity against Aspergillus fumigatus but Are Dispensable for Host Protection.
Aspergillosis
NADPH oxidase promotes neutrophil extracellular trap formation in pulmonary aspergillosis.
Asthma
A2A AR deficiency leads to impaired tracheal relaxation via NADPH oxidase pathway in allergic mice.
Asthma
Anti-inflammatory effects of apocynin, an inhibitor of NADPH oxidase, in airway inflammation.
Asthma
Defining the molecular role of gp91phox in the immune manifestation of acute allergic asthma using a preclinical murine model.
Asthma
Increased Expression of p22phox Mediates Airway Hyperresponsiveness in an Experimental Model of Asthma.
Asthma
NADPH oxidase 4 over-expression is associated with epithelial ciliary dysfunction in neutrophilic asthma.
Asthma
Nitric oxide-mediated activation of NADPH oxidase by salbutamol during acute asthma in children.
Asthma
Nonhematopoietic NADPH oxidase regulation of lung eosinophilia and airway hyperresponsiveness in experimentally induced asthma.
Asthma
Review - Nutraceuticals Can Target Asthmatic Bronchoconstriction: NADPH Oxidase-Dependent Oxidative Stress, RhoA and Calcium Dynamics.
Asthma
[Association of C242T and A640G polymorphisms in the gene for p22phox subunit of NADPH oxidase with the risk of bronchial asthma: a pilot study]
Astrocytoma
Nox2-based NADPH oxidase mediates HIV-1 Tat-induced up-regulation of VCAM-1/ICAM-1 and subsequent monocyte adhesion in human astrocytes.
Atherosclerosis
A Drosophila model for the screening of bioavailable NADPH oxidase inhibitors and antioxidants.
Atherosclerosis
A variant of p22(phox), involved in generation of reactive oxygen species in the vessel wall, is associated with progression of coronary atherosclerosis.
Atherosclerosis
Activated glycine receptors may decrease endosomal NADPH oxidase activity by opposing ClC-3-mediated efflux of chloride from endosomes.
Atherosclerosis
Active principle of kimchi, 3-(4'-hydroxyl-3',5'-dimethoxyphenyl)propionic acid, retards fatty streak formation at aortic sinus of apolipoprotein E knockout mice.
Atherosclerosis
Aldosterone administration to mice stimulates macrophage NADPH oxidase and increases atherosclerosis development: a possible role for angiotensin-converting enzyme and the receptors for angiotensin II and aldosterone.
Atherosclerosis
Ambient Particulates Alter Vascular Function through Induction of Reactive Oxygen and Nitrogen Species.
Atherosclerosis
An Inhibitor of Activated Blood Coagulation Factor X Shows Anti-Endothelial Senescence and Anti-Atherosclerotic Effects.
Atherosclerosis
Anti-atherosclerotic effects of dihomo-gamma-linolenic acid in ApoE-deficient mice.
Atherosclerosis
Antioxidative potential of fluvastatin via the inhibition of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase activity.
Atherosclerosis
C-C motif ligand 8 promotes atherosclerosis via NADPH oxidase 2/reactive oxygen species-induced endothelial permeability increase.
Atherosclerosis
C/EBP transcription factors regulate NADPH oxidase in human aortic smooth muscle cells.
Atherosclerosis
C242T polymorphism of NADPH oxidase p22 PHOX gene and ischemic cerebrovascular disease in the Japanese population.
Atherosclerosis
Clinical Application of NOX Activity and Other Oxidative Biomarkers in Cardiovascular Disease: A Critical Review.
Atherosclerosis
Dietary nitrate attenuated endothelial dysfunction and atherosclerosis in apolipoprotein E knockout mice fed a high-fat diet: A critical role for NADPH oxidase.
Atherosclerosis
Direct evidence of a role for Nox2 in superoxide production, reduced nitric oxide bioavailability and early atherosclerotic plaque formation in ApoE-/- mice.
Atherosclerosis
Effects of dietary sodium on reactive oxygen species formation and endothelial dysfunction in low-density lipoprotein receptor-deficient mice on high-fat diet.
Atherosclerosis
Endothelial Nox4 dysfunction aggravates atherosclerosis by inducing endoplasmic reticulum stress and soluble epoxide hydrolase.
Atherosclerosis
Endothelial Nox4-based NADPH oxidase regulates atherosclerosis via soluble epoxide hydrolase.
Atherosclerosis
Endothelium-restricted endothelin-1 overexpression in type 1 diabetes worsens atherosclerosis and immune cell infiltration via NOX1.
Atherosclerosis
Epigallocatechin-3-gallate Regulates NADPH Oxidase Expression in Human Umbilical Vein Endothelial Cells.
Atherosclerosis
Expression of p22-phox and gp91-phox, essential components of NADPH oxidase, increases after myocardial infarction.
Atherosclerosis
Galectin-3, a biomarker linking oxidative stress and inflammation with the clinical outcomes of patients with atherothrombosis.
Atherosclerosis
High glucose downregulates the number of caveolae in monocytes through oxidative stress from NADPH oxidase: implications for atherosclerosis.
Atherosclerosis
Homocysteine stimulates phosphorylation of NADPH oxidase p47phox and p67phox subunits in monocytes via protein kinase Cbeta activation.
Atherosclerosis
Identification of a functional leukocyte-type NADPH oxidase in human endothelial cells :a potential atherogenic source of reactive oxygen species.
Atherosclerosis
Impaired superoxide production due to a deficiency in phagocyte NADPH oxidase fails to inhibit atherosclerosis in mice.
Atherosclerosis
Increased phagocytic NADPH oxidase activity associates with coronary artery calcification in asymptomatic men.
Atherosclerosis
Inhibition of human neutrophil reactive oxygen species production and p67phox translocation by cigarette smoke extract.
Atherosclerosis
Inhibition of NADPH oxidase by apocynin attenuates progression of atherosclerosis.
Atherosclerosis
Inhibition of NADPH oxidase by vaspin may prevent progression of atherosclerosis.
Atherosclerosis
Inhibition of Rac1 GTPase Decreases Vascular Oxidative Stress, Improves Endothelial Function, and Attenuates Atherosclerosis Development in Mice.
Atherosclerosis
Interaction of hyperlipidemia and reactive oxygen species: Insights from the lipid-raft platform.
Atherosclerosis
Is leptin involved in phagocytic NADPH oxidase overactivity in obesity? Potential clinical implications.
Atherosclerosis
Is there a clinical role for oxidative stress biomarkers in atherosclerotic diseases?
Atherosclerosis
Letter by violi et Al regarding article, "molecular imaging of inflammation and platelet adhesion in advanced atherosclerosis effects of antioxidant therapy with NADPH oxidase inhibition".
Atherosclerosis
Lutein Prevents High Fat Diet-Induced Atherosclerosis in ApoE-Deficient Mice by Inhibiting NADPH Oxidase and Increasing PPAR Expression.
Atherosclerosis
MicroRNA-30e regulates TGF-?-mediated NADPH oxidase 4-dependent oxidative stress by Snai1 in atherosclerosis.
Atherosclerosis
MicroRNAs as Potential Mediators for Cigarette Smoking Induced Atherosclerosis.
Atherosclerosis
MiR-155 acts as an inhibitory factor in atherosclerosis-associated arterial pathogenesis by down-regulating NoxA1 related signaling pathway in ApoE-/- mouse.
Atherosclerosis
Modulation of oxidized-LDL receptor-1 (LOX1) contributes to the antiatherosclerosis effect of oleanolic acid.
Atherosclerosis
Molecular imaging of inflammation and platelet adhesion in advanced atherosclerosis effects of antioxidant therapy with NADPH oxidase inhibition.
Atherosclerosis
NADPH Oxidase Overactivity Underlies Telomere Shortening in Human Atherosclerosis.
Atherosclerosis
NADPH oxidase-dependent superoxide production is associated with carotid intima-media thickness in subjects free of clinical atherosclerotic disease.
Atherosclerosis
NADPH oxidases regulate CD44 and hyaluronic acid expression in thrombin-treated vascular smooth muscle cells and in atherosclerosis.
Atherosclerosis
Nitric oxide suppresses NADPH oxidase-dependent superoxide production by S-nitrosylation in human endothelial cells.
Atherosclerosis
Novel isoforms of NADPH oxidase in vascular physiology and pathophysiology.
Atherosclerosis
Nox activator 1: a potential target for modulation of vascular reactive oxygen species in atherosclerotic arteries.
Atherosclerosis
Nox isoforms in vascular pathophysiology: insights from transgenic and knockout mouse models.
Atherosclerosis
NOX4 NADPH Oxidase-Dependent Mitochondrial Oxidative Stress in Aging-Associated Cardiovascular Disease.
Atherosclerosis
NOXA1-dependent NADPH oxidase regulates redox signaling and phenotype of vascular smooth muscle cell during atherogenesis.
Atherosclerosis
Oxyradical stress increases the biosynthesis of 2-arachidonoylglycerol: involvement of NADPH oxidase.
Atherosclerosis
p-Cresyl sulfate is associated with carotid arteriosclerosis in hemodialysis patients and promotes atherogenesis in apoE-/- mice.
Atherosclerosis
Phagocytic NADPH oxidase overactivity underlies oxidative stress in metabolic syndrome.
Atherosclerosis
Phagocytic NADPH oxidase-dependent superoxide production stimulates matrix metalloproteinase-9: implications for human atherosclerosis.
Atherosclerosis
Pharmacological inhibition of histone deacetylase reduces NADPH oxidase expression, oxidative stress and the progression of atherosclerotic lesions in hypercholesterolemic apolipoprotein E-deficient mice; potential implications for human atherosclerosis.
Atherosclerosis
Pharmacological inhibition of NOX reduces atherosclerotic lesions, vascular ROS and immune-inflammatory responses in diabetic Apoe(-/-) mice.
Atherosclerosis
Physical inactivity increases oxidative stress, endothelial dysfunction, and atherosclerosis.
Atherosclerosis
Pleiotropic effects of ARB in vascular metabolism--focusing on atherosclerosis-based cardiovascular disease.
Atherosclerosis
Polymorphisms of the NADPH oxidase P22PHOX gene in a Caucasian population with intracranial aneurysms.
Atherosclerosis
Prolonged exposure to LPS increases iron, heme, and p22phox levels and NADPH oxidase activity in human aortic endothelial cells: inhibition by desferrioxamine.
Atherosclerosis
Quercetin attenuates high fat diet-induced atherosclerosis in apolipoprotein E knockout mice: A critical role of NADPH oxidase.
Atherosclerosis
Quercetin Inhibited Endothelial Dysfunction and Atherosclerosis in Apolipoprotein E-Deficient Mice: Critical Roles for NADPH Oxidase and Heme Oxygenase-1.
Atherosclerosis
Reactive Oxygen Species Can Provide Atheroprotection via NOX4-Dependent Inhibition of Inflammation and Vascular Remodeling.
Atherosclerosis
Reactive oxygen species in the cerebral circulation: physiological roles and therapeutic implications for hypertension and stroke.
Atherosclerosis
Reduced atherosclerotic burden in subjects with genetically determined low oxidative stress.
Atherosclerosis
Regulation of NADPH oxidase subunit p22(phox) by NF-kB in human aortic smooth muscle cells.
Atherosclerosis
Regulation of superoxide anion production by NADPH oxidase in monocytes/macrophages: contributions to atherosclerosis.
Atherosclerosis
Role of redox factor-1 in hyperhomocysteinemia-accelerated atherosclerosis.
Atherosclerosis
S-Glutathionylation Reshapes Our Understanding of Endothelial Nitric Oxide Synthase Uncoupling and Nitric Oxide/Reactive Oxygen Species-Mediated Signaling.
Atherosclerosis
S100A12 in Vascular Smooth Muscle Accelerates Vascular Calcification in Apolipoprotein E-Null Mice by Activating an Osteogenic Gene Regulatory Program.
Atherosclerosis
S17834, a new inhibitor of cell adhesion and atherosclerosis that targets nadph oxidase.
Atherosclerosis
Selective recapitulation of conserved and nonconserved regions of putative NOXA1 protein activation domain confers isoform-specific inhibition of Nox1 oxidase and attenuation of endothelial cell migration.
Atherosclerosis
Superoxide dismutase mimetic M40403 improves endothelial function in apolipoprotein(E)-deficient mice.
Atherosclerosis
Suppressing NADPH oxidase-dependent oxidative stress in the vasculature with nitric oxide donors.
Atherosclerosis
The angiotensin-converting enzyme insertion/deletion polymorphism is associated with phagocytic NADPH oxidase-dependent superoxide generation: potential implication in hypertension.
Atherosclerosis
The clinical research for Ganoderan's effect on preventing and treating cerebral arteriosclerosis through inhibiting NADPH oxidizing enzyme expression.
Atherosclerosis
The Renin Angiotensin aldosterone system in hypertension: roles of insulin resistance and oxidative stress.
Atherosclerosis
The role of NADPH oxidase in vascular disease--hypertension, atherosclerosis & stroke.
Atherosclerosis
The role of oxidative stress and NADPH oxidase in the pathogenesis of atherosclerosis.
Atherosclerosis
The role of the methoxyphenol apocynin, a vascular NADPH oxidase inhibitor, as a chemopreventative agent in the potential treatment of cardiovascular diseases.
Atherosclerosis
Thioredoxin attenuates oxidized low-density lipoprotein induced oxidative stress in human umbilical vein endothelial cells by reducing NADPH oxidase activity.
Atherosclerosis
Thioredoxin-1/peroxiredoxin-1 as sensors of oxidative stress mediated by NADPH oxidase activity in atherosclerosis.
Atherosclerosis
Tyrosine kinase-mediated activation of NADPH oxidase enhances proliferative capacity of diabetic vascular smooth muscle cells.
Atherosclerosis
[Effect of Porphyromonas gingivalis infection on atherosclerosis in apolipoprotein-E knockout mice].
Atherosclerosis
[Modulation by some fatty acids of protein kinase C-dependent NADPH oxidase in human adherent monocyte: mechanism of action, possible implication in atherogenesis]
Atherosclerosis
[NADPH oxidase activity does not affect cellular cholesterol loading in vascular smooth muscle cells.]
Atrial Fibrillation
Apocynin: a potent NADPH oxidase inhibitor for the management of atrial fibrillation.
Atrial Fibrillation
Atrial myocardial nox2 containing NADPH oxidase activity contribution to oxidative stress in mitral regurgitation: potential mechanism for atrial remodeling.
Atrial Fibrillation
Different behaviour of NOX2 activation in patients with paroxysmal/persistent or permanent atrial fibrillation.
Atrial Fibrillation
Oxidative stress in atrial fibrillation: an emerging role of NADPH oxidase.
Atrial Fibrillation
The More Effective Treatment of Atrial Fibrillation Applying the Natural Compounds; as NADPH Oxidase and Ion Channel Inhibitors.
Autoimmune Diseases
NADPH oxidase is required for neutrophil-dependent autoantibody-induced tissue damage.
Autoimmune Diseases
Ncf1 (p47phox) polymorphism determines oxidative burst and the severity of arthritis in rats and mice.
Autoimmune Diseases
Oxygen radical production and severity of the Guillain--Barré syndrome.
Bacteremia
NADPH oxidase deficient mice develop colitis and bacteremia upon infection with normally avirulent, TTSS-1- and TTSS-2-deficient Salmonella Typhimurium.
Bacterial Infections
A Localized Pseudomonas syringae Infection Triggers Systemic Clock Responses in Arabidopsis.
Bacterial Infections
Altered Pattern of Naïve and Memory B cells and B1 Cells in Patients with Chronic Granulomatous Disease.
Bacterial Infections
Cytosolic phospholipase A2-alpha is necessary for platelet-activating factor biosynthesis, efficient neutrophil-mediated bacterial killing, and the innate immune response to pulmonary infection: cPLA2-alpha does not regulate neutrophil NADPH oxidase activity.
Bacterial Infections
Evasion of Legionella pneumophila from the bactericidal system by reactive oxygen species (ROS) in macrophages.
Bacterial Infections
NADPH oxidase but not myeloperoxidase protects lymphopenic mice from spontaneous infections.
Bacterial Infections
NADPH oxidases: an overview from structure to innate immunity-associated pathologies.
Bacterial Infections
Partial correction of neutrophil dysfunction by oral galactose therapy in glycogen storage disease type Ib.
Bacterial Infections
Phosphatidylinositol 3-phosphate-dependent and -independent functions of p40phox in activation of the neutrophil NADPH oxidase.
Bacterial Infections
Polymorphonuclear leukocyte-mediated cell and tissue injury: oxygen metabolites and their relations to human disease.
Bacterial Infections
Role of NADPH oxidase versus neutrophil proteases in antimicrobial host defense.
Bacterial Infections
The metabolic and phagocytic activities of leukocytes from patients receiving corticosteroid and radiation therapy, and patients with bacterial infections.
Bacterial Infections
[Studies on relationships between the inhibition of human neutrophil NADPH oxidase by anti-inflammatory drugs and development of bacterial infections]
Barrett Esophagus
NADPH oxidase NOX5-S mediates acid-induced cyclooxygenase-2 expression via activation of NF-kappaB in Barrett's esophageal adenocarcinoma cells.
Barrett Esophagus
STAT5 mediates PAF-induced NADPH oxidase NOX5-S expression in Barrett's esophageal adenocarcinoma cells.
Blast Crisis
Inhibition of the NADPH oxidase regulates heme oxygenase 1 expression in chronic myeloid leukemia.
Bone Resorption
Osteoclastic superoxide production and bone resorption: stimulation and inhibition by modulators of NADPH oxidase.
Brain Edema
Administration of pigment epithelium-derived factor (PEDF) inhibits cold injury-induced brain edema in mice.
Brain Edema
Attenuation of brain edema and spatial learning de?cits by the inhibition of NADPH oxidase activity using apocynin following diffuse traumatic brain injury in rats.
Brain Edema
NADPH oxidase inhibition improves neurological outcomes in surgically-induced brain injury.
Brain Edema
Normobaric hyperoxia inhibits NADPH oxidase-mediated matrix metalloproteinase-9 induction in cerebral microvessels in experimental stroke.
Brain Edema
Peroxynitrite activates NLRP3 inflammasome and contributes to hemorrhagic transformation and poor outcome in ischemic stroke with hyperglycemia.
Brain Infarction
CK2 is a novel negative regulator of NADPH oxidase and a neuroprotectant in mice after cerebral ischemia.
Brain Injuries
Ca(2+)/Calmodulin-Dependent Protein Kinase II Contributes to Hypoxic Ischemic Cell Death in Neonatal Hippocampal Slice Cultures.
Brain Injuries
Cellular and temporal expression of NADPH oxidase (NOX) isotypes after brain injury.
Brain Injuries
CK2 is a novel negative regulator of NADPH oxidase and a neuroprotectant in mice after cerebral ischemia.
Brain Injuries
Excess salt causes cerebral neuronal apoptosis and inflammation in stroke-prone hypertensive rats through angiotensin II-induced NADPH oxidase activation.
Brain Injuries
Hyperbaric oxygen suppresses NADPH oxidase in a rat subarachnoid hemorrhage model.
Brain Injuries
Increased NADPH oxidase-derived superoxide is involved in the neuronal cell death induced by hypoxia-ischemia in neonatal hippocampal slice cultures.
Brain Injuries
Ischemic stroke injury is reduced in mice lacking a functional NADPH oxidase.
Brain Injuries
Mechanisms regulating superoxide generation in experimental models of phenylketonuria: An essential role of NADPH oxidase.
Brain Injuries
Modulation of NADPH oxidase activation in cerebral ischemia/reperfusion injury in rats.
Brain Injuries
NADPH oxidase inhibition improves neurological outcomes in surgically-induced brain injury.
Brain Injuries
NADPH oxidase plays a central role in blood-brain barrier damage in experimental stroke.
Brain Injuries
Neuroprotection by glucose-6-phosphate dehydrogenase and the pentose phosphate pathway.
Brain Injuries
Neuroprotective effect of hyperbaric oxygen in a rat model of subarachnoid hemorrhage.
Brain Injuries
Pharmacological and genetic inhibition of NADPH oxidase does not reduce brain damage in different models of perinatal brain injury in newborn mice.
Brain Injuries
Status epilepticus results in persistent overproduction of reactive oxygen species, inhibition of which is neuroprotective.
Brain Injuries, Traumatic
Activation of mGluR5 and Inhibition of NADPH Oxidase Improves Functional Recovery after Traumatic Brain Injury.
Brain Injuries, Traumatic
Attenuation of brain edema and spatial learning de?cits by the inhibition of NADPH oxidase activity using apocynin following diffuse traumatic brain injury in rats.
Brain Injuries, Traumatic
Critical role of NADPH oxidase in neuronal oxidative damage and microglia activation following traumatic brain injury.
Brain Injuries, Traumatic
Gp91phox (NOX2) in classically activated microglia exacerbates traumatic brain injury.
Brain Injuries, Traumatic
NADPH oxidase 2 deletion enhances neurogenesis following traumatic brain injury.
Brain Injuries, Traumatic
NADPH oxidase inhibition improves neurological outcome in experimental traumatic brain injury.
Brain Injuries, Traumatic
Prevention of traumatic brain injury-induced neuronal death by inhibition of NADPH oxidase activation.
Brain Injuries, Traumatic
The NADPH oxidase NOX2 mediates loss of parvalbumin interneurons in traumatic brain injury: human autoptic immunohistochemical evidence.
Brain Ischemia
Acute NADPH oxidase activation potentiates cerebrovascular permeability response to bradykinin in ischemia-reperfusion.
Brain Ischemia
Alpha-Lipoic Acid Attenuates Cerebral Ischemia and Reperfusion Injury via Insulin Receptor and PI3K/Akt-Dependent Inhibition of NADPH Oxidase.
Brain Ischemia
CK2 is a novel negative regulator of NADPH oxidase and a neuroprotectant in mice after cerebral ischemia.
Brain Ischemia
Effect of the NADPH oxidase inhibitor apocynin on ischemia-reperfusion hippocampus injury in rat brain.
Brain Ischemia
Effects of Vitamin D3 on the NADPH Oxidase and Matrix Metalloproteinase 9 in an Animal Model of Global Cerebral Ischemia.
Brain Ischemia
Inhibition of gp91(phox) contributes towards normobaric hyperoxia afforded neuroprotection in focal cerebral ischemia.
Brain Ischemia
mGluR1 antagonist decreased NADPH oxidase activity and superoxide production after transient focal cerebral ischemia.
Brain Ischemia
Modulation of NADPH oxidase activation in cerebral ischemia/reperfusion injury in rats.
Brain Ischemia
NADPH oxidase mediates striatal neuronal injury after transient global cerebral ischemia.
Brain Ischemia
NADPH oxidase-mediated oxidative damage to proteins in the postsynaptic density after transient cerebral ischemia and reperfusion.
Brain Ischemia
Neuronal expression of the NADPH oxidase NOX4, and its regulation in mouse experimental brain ischemia.
Brain Ischemia
Oral phycocyanobilin may diminish the pathogenicity of activated brain microglia in neurodegenerative disorders.
Brain Ischemia
Oxidative Stress and NAD(+) in Ischemic Brain Injury: Current Advances and Future Perspectives.
Brain Ischemia
Phospholipase A(2), reactive oxygen species, and lipid peroxidation in cerebral ischemia.
Brain Ischemia
Release of mitochondrial apoptogenic factors and cell death are mediated by CK2 and NADPH oxidase.
Brain Ischemia
Role of Rac1 GTPase in NADPH oxidase activation and cognitive impairment following cerebral ischemia in the rat.
Brain Ischemia
Suppression of the inflammatory response by diphenyleneiodonium after transient focal cerebral ischemia.
Brain Ischemia
The roles of NADPH oxidase and phospholipases A2 in oxidative and inflammatory responses in neurodegenerative diseases.
Breast Neoplasms
Metastatic breast carcinoma induces vascular endothelial dysfunction in Balb-c mice: Role of the tumor necrosis factor-? and NADPH oxidase.
Breast Neoplasms
NADPH quinone oxidoreductase 1 mediates breast cancer cell resistance to thymoquinone-induced apoptosis.
Breast Neoplasms
NADPH: Quinone oxidoreductase 1 (NQO1) mediated anti-cancer effects of plumbagin in endocrine resistant MCF7 breast cancer cells.
Breast Neoplasms
Polymorphisms in oxidative stress-related genes and postmenopausal breast cancer risk.
Breast Neoplasms
Pro-survival of estrogen receptor-negative breast cancer cells is regulated by a BLT2-reactive oxygen species-linked signaling pathway.
Breast Neoplasms
Redox-modulating agents target NOX2-dependent IKK? oncogenic kinase expression and proliferation in human breast cancer cell lines.
Breast Neoplasms
Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells.
Breast Neoplasms
Tetrabromobisphenol A Induces MMP-9 Expression via NADPH Oxidase and the activation of ROS, MAPK, and Akt Pathways in Human Breast Cancer MCF-7 Cells.
Bronchiolitis
Anti-inflammatory action of erythromycin. Its inhibitory effect on neutrophil NADPH oxidase activity.
Burkitt Lymphoma
The NADPH oxidase inhibitor imipramine-blue in the treatment of burkitt lymphoma.
Carcinogenesis
Apocynin, an NADPH oxidase inhibitor, suppresses rat prostate carcinogenesis.
Carcinogenesis
Association between NADPH oxidase (NOX) and lung cancer: a systematic review and meta-analysis.
Carcinogenesis
Carcinogenesis and Reactive Oxygen Species Signaling: Interaction of the NADPH Oxidase NOX1-5 and Superoxide Dismutase 1-3 Signal Transduction Pathways.
Carcinogenesis
Minimizing the cancer-promotional activity of cox-2 as a central strategy in cancer prevention.
Carcinogenesis
NADPH oxidase activation is required in reactive oxygen species generation and cell transformation induced by hexavalent chromium.
Carcinogenesis
NADPH Oxidase as a Target for Modulation of Radiation Response; Implications to Carcinogenesis and Radiotherapy.
Carcinogenesis
NADPH oxidase biology and the regulation of tyrosine kinase receptor signaling and cancer drug cytotoxicity.
Carcinogenesis
NADPH oxidase DUOX1 and DUOX2 but not NOX4 are independent predictors in hepatocellular carcinoma after hepatectomy.
Carcinogenesis
NADPH oxidase NOX4 supports renal tumorigenesis by promoting the expression and nuclear accumulation of HIF2?.
Carcinogenesis
NF-?B-induced NOX1 activation promotes gastric tumorigenesis through the expansion of SOX2-positive epithelial cells.
Carcinogenesis
ROS signaling by NADPH oxidase 5 modulates the proliferation and survival of prostate carcinoma cells.
Carcinogenesis
Suppressive effects of the NADPH oxidase inhibitor apocynin on intestinal tumorigenesis in obese KK-A(y) and Apc mutant Min mice.
Carcinogenesis
Targeting NOX, INOS and COX-2 in inflammatory cells: Chemoprevention using food phytochemicals.
Carcinogenesis
The NADPH oxidase inhibitor apocynin inhibits UVB-induced skin carcinogenesis.
Carcinogenesis
Understanding the biology of reactive oxygen species and their link to cancer: NADPH oxidases as novel pharmacological targets.
Carcinoma
ALKBH3 Contributes to Survival and Angiogenesis of Human Urothelial Carcinoma Cells through NADPH Oxidase and Tweak/Fn14/VEGF Signals.
Carcinoma
HaCaT keratinocytes overexpressing the S100 proteins S100A8 and S100A9 show increased NADPH oxidase and NF-kappaB activities.
Carcinoma
miR-372 inhibits p62 in head and neck squamous cell carcinoma in vitro and in vivo.
Carcinoma
NADPH oxidase and uncoupled nitric oxide synthase are major sources of reactive oxygen species in oral squamous cell carcinoma. Potential implications for immune regulation in high oxidative stress conditions.
Carcinoma
NADPH-oxidase and a hydrogen peroxide-sensitive K+ channel may function as an oxygen sensor complex in airway chemoreceptors and small cell lung carcinoma cell lines.
Carcinoma
NOX2 (gp91 phox) is a predominant O2 sensor in a human airway chemoreceptor cell line: biochemical, molecular and electrophysiological evidence.
Carcinoma
ROS generation via NOX4 and its utility in the cytological diagnosis of urothelial carcinoma of the urinary bladder.
Carcinoma
TG-interacting factor-induced superoxide production from NADPH oxidase contributes to the migration/invasion of urothelial carcinoma.
Carcinoma
[Interaction of polymorphisms of PPAR-?2 gene -C34G and NADPH oxidase subunit p22phox gene -C242T with Helicobacter pylori infection in esophageal squamous cell carcinoma].
Carcinoma, Hepatocellular
Divergent pathways for TNF and C(2)-ceramide toxicity in HTC hepatoma cells.
Carcinoma, Hepatocellular
Fluvastatin attenuates hepatic steatosis-induced fibrogenesis in rats through inhibiting paracrine effect of hepatocyte on hepatic stellate cells.
Carcinoma, Hepatocellular
Mechanism of apoptosis induced by apigenin in HepG2 human hepatoma cells: involvement of reactive oxygen species generated by NADPH oxidase.
Carcinoma, Hepatocellular
NADPH oxidase DUOX1 and DUOX2 but not NOX4 are independent predictors in hepatocellular carcinoma after hepatectomy.
Carcinoma, Hepatocellular
NADPH oxidase NOX1 controls autocrine growth of liver tumor cells through up-regulation of the epidermal growth factor receptor pathway.
Carcinoma, Hepatocellular
Role of reactive oxygen species generated by NADPH oxidase in the mechanism of activation of K(+)-Cl(-)-cotransport by N-ethylmaleimide in HepG2 human hepatoma cells.
Carcinoma, Non-Small-Cell Lung
NADPH oxidase 1-dependent ROS is crucial for TLR4 signaling to promote tumor metastasis of non-small cell lung cancer.
Carcinoma, Renal Cell
NADPH oxidase 4 promotes cisplatin-induced acute kidney injury via ROS-mediated programmed cell death and inflammation.
Carcinoma, Squamous Cell
Increased level of the p67phox subunit of NADPH oxidase by 4HPR in head and neck squamous carcinoma cells.
Carcinoma, Squamous Cell
miR-372 inhibits p62 in head and neck squamous cell carcinoma in vitro and in vivo.
Cardio-Renal Syndrome
Chronic Kidney Disease and Disproportionally Increased Cardiovascular Damage: Does Oxidative Stress Explain the Burden?
Cardiomegaly
3,3',4',5,7-Pentamethylquercetin reduces angiotensin II-induced cardiac hypertrophy and apoptosis in rats.
Cardiomegaly
Activation of NADPH oxidase during progression of cardiac hypertrophy to failure.
Cardiomegaly
Administration of rosmarinic acid reduces cardiopathology and blood pressure through inhibition of p22phox NADPH oxidase in fructose-fed hypertensive rats.
Cardiomegaly
Angiotensin II-dependent chronic hypertension and cardiac hypertrophy are unaffected by gp91phox-containing NADPH oxidase.
Cardiomegaly
Apocynin attenuates pressure overload-induced cardiac hypertrophy in rats by reducing levels of reactive oxygen species.
Cardiomegaly
Cardioprotective effects mediated by angiotensin II type 1 receptor blockade and enhancing angiotensin 1-7 in experimental heart failure in angiotensin-converting enzyme 2-null mice.
Cardiomegaly
Contrasting roles of NADPH oxidase isoforms in pressure-overload versus angiotensin II-induced cardiac hypertrophy.
Cardiomegaly
Critical role of X-box binding protein 1 in NADPH oxidase 4-triggered cardiac hypertrophy is mediated by receptor interacting protein kinase 1.
Cardiomegaly
Differential involvement of various sources of reactive oxygen species in thyroxin-induced hemodynamic changes and contractile dysfunction of the heart and diaphragm muscles.
Cardiomegaly
Enhancement of cardiac oxidative stress by tachycardia and its critical role in cardiac hypertrophy and fibrosis.
Cardiomegaly
Extracts enriched in different polyphenolic families normalize increased cardiac NADPH oxidase expression while having differential effects on insulin resistance, hypertension, and cardiac hypertrophy in high-fructose-fed rats.
Cardiomegaly
Impaired endothelial regulation of ventricular relaxation in cardiac hypertrophy: role of reactive oxygen species and NADPH oxidase.
Cardiomegaly
Inhibition of the ROS-EGFR Pathway Mediates the Protective Action of Nox1/4 Inhibitor GKT137831 against Hypertensive Cardiac Hypertrophy via Suppressing Cardiac Inflammation and Activation of Akt and ERK1/2.
Cardiomegaly
NADPH oxidase-dependent redox signalling in cardiac hypertrophy, remodelling and failure.
Cardiomegaly
Nox2-containing NADPH oxidase and Akt activation play a key role in angiotensin II-induced cardiomyocyte hypertrophy.
Cardiomegaly
Olmesartan inhibits cardiac hypertrophy in mice overexpressing renin independently of blood pressure: its beneficial effects on ACE2/Ang(1-7)/Mas axis and NADPH oxidase expression.
Cardiomegaly
Pathogenesis of target organ damage in hypertension: role of mitochondrial oxidative stress.
Cardiomegaly
Pivotal role of a gp91(phox)-containing NADPH oxidase in angiotensin II-induced cardiac hypertrophy in mice.
Cardiomegaly
Polydatin prevents angiotensin II-induced cardiac hypertrophy and myocardial superoxide generation.
Cardiomegaly
Proteomic profiling reveals comprehensive insights into adrenergic receptor-mediated hypertrophy in neonatal rat cardiomyocytes.
Cardiomegaly
Puerarin Suppresses Angiotensin II-Induced Cardiac Hypertrophy by Inhibiting NADPH Oxidase Activation and Oxidative Stress-Triggered AP-1 Signaling Pathways.
Cardiomegaly
Resveratrol ameliorates cardiac oxidative stress in diabetes through deacetylation of NFkB-p65 and histone 3.
Cardiomegaly
Role of AT1 receptor in isoproterenol-induced cardiac hypertrophy and oxidative stress in mice.
Cardiomegaly
Stachydrine Protects Against Pressure Overload-Induced Cardiac Hypertrophy by Suppressing Autophagy.
Cardiomegaly
The antioxidant tempol inhibits cardiac hypertrophy in the insulin-resistant GLUT4-deficient mouse in vivo.
Cardiomegaly
Vascular but not cardiac remodeling is associated with superoxide production in angiotensin II hypertension.
Cardiomegaly
[Oxidative stress and calcium/calmodulin-dependent protein kinase II contribute to the development of sustained ? adrenergic receptor-stimulated cardiac hypertrophy in rats].
Cardiomyopathies
Astragaloside IV alleviates doxorubicin induced cardiomyopathy by inhibiting NADPH oxidase derived oxidative stress.
Cardiomyopathies
Hemin decreases cardiac oxidative stress and fibrosis in a rat model of systemic hypertension via PI3K/Akt signaling.
Cardiomyopathies
Increase of NADPH oxidase 3 in heart failure of hereditary cardiomyopathy 1.
Cardiomyopathies
NecroX-7 prevents oxidative stress-induced cardiomyopathy by inhibition of NADPH oxidase activity in rats.
Cardiomyopathies
NOX Inhibition Improves ?-Adrenergic Stimulated Contractility and Intracellular Calcium Handling in the Aged Rat Heart.
Cardiomyopathies
Oxygen free radical release in human failing myocardium is associated with increased activity of rac1-GTPase and represents a target for statin treatment.
Cardiomyopathies
Phosphoinositide 3-kinase (p110?) gene delivery limits diabetes-induced cardiac NADPH oxidase and cardiomyopathy in a mouse model with established diastolic dysfunction.
Cardiomyopathies
Ramipril restores PPAR?/? and PPAR? expressions and reduces cardiac NADPH oxidase but fails to restore cardiac function and accompanied myosin heavy chain ratio shift in severe anthracycline-induced cardiomyopathy in rat.
Cardiomyopathies
Role of alpha1-adrenoreceptors in cocaine-induced NADPH oxidase expression and cardiac dysfunction.
Cardiomyopathies
Therapeutic targeting of oxidative stress with coenzyme Q10 counteracts exaggerated diabetic cardiomyopathy in a mouse model of diabetes with diminished PI3K(p110?) signaling.
Cardiomyopathy, Dilated
Enhanced susceptibility to biomechanical stress in ACE2 null mice is prevented by loss of the p47phox NADPH oxidase subunit.
Cardiomyopathy, Dilated
Over-expression of a cardiac-specific human dopamine D5 receptor mutation in mice causes a dilated cardiomyopathy through ROS over-generation by NADPH oxidase activation and Nrf2 degradation.
Cardiomyopathy, Dilated
Oxygen free radical release in human failing myocardium is associated with increased activity of rac1-GTPase and represents a target for statin treatment.
Cardiotoxicity
17?-estradiol protects against doxorubicin-induced cardiotoxicity in male Sprague-Dawley rats by regulating NADPH oxidase and apoptosis genes.
Cardiotoxicity
Association of anthracycline-related cardiac histological lesions with NADPH oxidase functional polymorphisms.
Cardiotoxicity
Association of NADPH oxidase polymorphisms with anthracycline-induced cardiotoxicity in the RICOVER-60 trial of patients with aggressive CD20(+) B-cell lymphoma.
Cardiotoxicity
Chronic cocaine-induced cardiac oxidative stress and mitogen-activated protein kinase activation: the role of Nox2 oxidase.
Cardiotoxicity
Corrigendum to "Exploring the protective role of apocynin, a specific NADPH oxidase inhibitor, in cisplatin-induced cardiotoxicity in rats" [Chem. Biol. Interact. 207 (2014) 58-66].
Cardiotoxicity
Exploring the protective role of apocynin, a specific NADPH oxidase inhibitor, in cisplatin-induced cardiotoxicity in rats.
Cardiotoxicity
Grape Seed Proanthocyanidin Ameliorates Cardiac Toxicity Induced by Boldenone Undecylenate through Inhibition of NADPH Oxidase and Reduction in the Expression of NOX2 and NOX4.
Cardiotoxicity
Nox2 NADPH Oxidase Promotes Pathologic Cardiac Remodeling Associated with Doxorubicin Chemotherapy.
Cardiotoxicity
p-Cresyl sulfate aggravates cardiac dysfunction associated with chronic kidney disease by enhancing apoptosis of cardiomyocytes.
Cardiotoxicity
Rac1 signalling mediates doxorubicin-induced cardiotoxicity through both reactive oxygen species-dependent and -independent pathways.
Cardiovascular Diseases
Acute inhibition of superoxide formation and Rac1 activation by nitric oxide and iloprost in human vascular smooth muscle cells in response to the thromboxane A2 analogue, U46619.
Cardiovascular Diseases
Angiotensin-Generated Reactive Oxygen Species in Brain and Pathogenesis of Cardiovascular Diseases.
Cardiovascular Diseases
Anthracycline-Induced Cardiotoxicity: The Role of Endothelial Dysfunction.
Cardiovascular Diseases
Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets.
Cardiovascular Diseases
Coordination between NADPH oxidase and vascular peroxidase 1 promotes dysfunctions of endothelial progenitor cells in hypoxia-induced pulmonary hypertensive rats.
Cardiovascular Diseases
Current status of NADPH oxidase research in cardiovascular pharmacology.
Cardiovascular Diseases
D1-Like Receptors Regulate NADPH Oxidase Activity and Subunit Expression in Lipid Raft Microdomains of Renal Proximal Tubule Cells.
Cardiovascular Diseases
Dysfunctional endothelial progenitor cells in cardiovascular diseases: role of NADPH oxidase.
Cardiovascular Diseases
Epigallocatechin-3-gallate Regulates NADPH Oxidase Expression in Human Umbilical Vein Endothelial Cells.
Cardiovascular Diseases
Mitochondrial reactive oxygen species and calcium uptake regulate activation of phagocytic NADPH oxidase.
Cardiovascular Diseases
NADPH oxidase 1 mediates upregulation of thromboxane A(2) synthase in human vascular smooth muscle cells: Inhibition with iloprost.
Cardiovascular Diseases
NADPH oxidase CYBA polymorphisms, oxidative stress and cardiovascular diseases.
Cardiovascular Diseases
NADPH oxidase-mediated oxidative stress: genetic studies of the p22(phox) gene in hypertension.
Cardiovascular Diseases
NADPH oxidases and oxidase crosstalk in cardiovascular diseases: novel therapeutic targets.
Cardiovascular Diseases
NADPH oxidases in cardiovascular disease: insights from in vivo models and clinical studies.
Cardiovascular Diseases
NADPH oxidases in the vasculature: molecular features, roles in disease and pharmacological inhibition.
Cardiovascular Diseases
NADPH oxidases of the brain: distribution, regulation, and function.
Cardiovascular Diseases
Nicotinamide adenine dinucleotide phosphate oxidase: a promiscuous therapeutic target for cardiovascular drugs?
Cardiovascular Diseases
Nox isoforms in vascular pathophysiology: insights from transgenic and knockout mouse models.
Cardiovascular Diseases
Oxidative stress, inflammation, and peritoneal dialysis: A molecular biology approach.
Cardiovascular Diseases
p22phox C242T Single-Nucleotide Polymorphism Inhibits Inflammatory Oxidative Damage to Endothelial Cells and Vessels.
Cardiovascular Diseases
Procyanidins from grape pomace are suitable inhibitors of human endothelial NADPH oxidase.
Cardiovascular Diseases
Recent development in the effects of statins on cardiovascular disease through Rac1 and NADPH oxidase.
Cardiovascular Diseases
Relation between development of cardiovascular disease and the C242T CYBA polymorphism of the NADPH oxidase in ESRD patients.
Cardiovascular Diseases
Requirement for Rac1-dependent NADPH oxidase in the cardiovascular and dipsogenic actions of angiotensin II in the brain.
Cardiovascular Diseases
Role of Nox inhibitors plumbagin, ML090 and gp91ds-tat peptide on homocysteine thiolactone induced blood vessel dysfunction.
Cardiovascular Diseases
Role of nox2-based NADPH oxidase in bone marrow and progenitor cell function involved in neovascularization induced by hindlimb ischemia.
Cardiovascular Diseases
Suppression of oxidative stress in the endothelium and vascular wall.
Cardiovascular Diseases
The C242T CYBA polymorphism as a major determinant of NADPH oxidase activity in patients with cardiovascular disease.
Cardiovascular Diseases
The endothelin receptor antagonist CPU0213 is more effective than aminoguanidine to attenuate isoproterenol-induced vascular abnormality by suppressing overexpression of NADPH Oxidas, ETA, ETB, and MMP9 in the vasculature.
Cardiovascular Diseases
The role of the methoxyphenol apocynin, a vascular NADPH oxidase inhibitor, as a chemopreventative agent in the potential treatment of cardiovascular diseases.
Cardiovascular Diseases
Upregulation of intermediate-conductance Ca2+-activated K+ channels (KCNN4) in porcine coronary smooth muscle requires NADPH oxidase 5 (NOX5).
Carotid Artery Diseases
Association of the C242T polymorphism in the NADPH oxidase p22 phox gene with carotid atherosclerosis in Slovenian patients with type 2 diabetes.
Carotid Stenosis
Attenuation of Brain Damage and Cognitive Impairment by Direct Renin Inhibition in Mice With Chronic Cerebral Hypoperfusion.
Carotid Stenosis
Phagocytic NADPH oxidase-dependent superoxide production stimulates matrix metalloproteinase-9: implications for human atherosclerosis.
Central Nervous System Diseases
Control of JNK for an activation of NADPH oxidase in LPS-stimulated BV2 microglia.
Central Nervous System Diseases
NADPH oxidases - molecular understanding finally reaching the clinical level?
Central Nervous System Diseases
NOX Inhibitors as a Therapeutic Strategy for Stroke and Neurodegenerative Disease.
Cerebral Hemorrhage
Effect of Pretreatment with the NADPH Oxidase Inhibitor Apocynin on the Therapeutic Efficacy of Human Placenta-Derived Mesenchymal Stem Cells in Intracerebral Hemorrhage.
Cerebral Hemorrhage
P2X7 receptor activation aggravates NADPH oxidase 2-induced oxidative stress after intracerebral hemorrhage.
Cerebral Infarction
Apocynin attenuates cerebral infarction after transient focal ischaemia in rats.
Cerebral Infarction
NADPH oxidase-mediated oxidative damage to proteins in the postsynaptic density after transient cerebral ischemia and reperfusion.
Cerebral Small Vessel Diseases
NADPH oxidase polymorphisms in cerebral small vessel disease.
Cerebrovascular Disorders
Association between NADPH oxidase p22(phox) C242T polymorphism and ischemic cerebrovascular disease: a meta-analysis.
Cerebrovascular Disorders
C242T polymorphism of NADPH oxidase p22 PHOX gene and ischemic cerebrovascular disease in the Japanese population.
Cerebrovascular Disorders
NADPH oxidase p22phox C242T polymorphism and ischemic cerebrovascular disease: an updated meta-analysis.
Cerebrovascular Disorders
Pathophysiology and Therapeutic Potential of NADPH Oxidases in Ischemic Stroke-Induced Oxidative Stress.
Cerebrovascular Disorders
Polymorphisms of the NADPH oxidase P22PHOX gene in a Caucasian population with intracranial aneurysms.
Cerebrovascular Disorders
The role of oxidative stress and NADPH oxidase in cerebrovascular disease.
Cerebrovascular Disorders
The role of secretory phospholipase A2 in the central nervous system and neurological diseases.
Chagas Disease
NADPH oxidase inhibition ameliorates Trypanosoma cruzi-induced myocarditis during Chagas disease.
Chagas Disease
Ovarian dual oxidase (Duox) activity is essential for insect eggshell hardening and waterproofing.
Chediak-Higashi Syndrome
Defective priming of the phagocyte oxidative burst in a child with recurrent intracellular infections.
Cholangiocarcinoma
Free radicals enzymatically triggered by Clonorchis sinensis excretory-secretory products cause NF-?B-mediated inflammation in human cholangiocarcinoma cells.
Cholera
Activation of the superoxide-generating NADPH oxidase of macrophages by sodium dodecyl sulfate in a soluble cell-free system: evidence for involvement of a G protein.
Cholera
Concanavalin A stimulation of O2 consumption in electropermeabilized neutrophils via a pertussis toxin-insensitive G protein.
Cholera
Regulation of neutrophil NADPH oxidase activation in a cell-free system by guanine nucleotides and fluoride. Evidence for participation of a pertussis and cholera toxin-insensitive G protein.
Cholera
Subcellular distribution and membrane association of human neutrophil substrates for ADP-ribosylation by pertussis toxin and cholera toxin.
Choriocarcinoma
Expression of NADPH oxidase isoform 1 (Nox1) in human placenta: involvement in preeclampsia.
Choroidal Neovascularization
Breaking barriers: insight into the pathogenesis of neovascular age-related macular degeneration.
Choroidal Neovascularization
The role of vascular endothelial growth factor-induced activation of NADPH oxidase in choroidal endothelial cells and choroidal neovascularization.
Clonorchiasis
The Overactivation of NADPH Oxidase during Clonorchis sinensis Infection and the Exposure to N-Nitroso Compounds Promote Periductal Fibrosis.
Coinfection
Coinfection with Leishmania major and Staphylococcus aureus enhances the pathologic responses to both microbes through a pathway involving IL-17A.
Coinfection
Coinfection with PCV2 and SS2 enhances the survival of SS2 in swine tracheal epithelial cells by decreasing reactive oxygen species production.
Coinfection
Nox2-derived oxidative stress results in inefficacy of antibiotics against post-influenza S. aureus pneumonia.
Coinfection
Trichinella spiralis infection affects p47(phox) protein expression in guinea-pig alveolar macrophages.
Colitis
5-Hydroxytryptamine (5-HT)-exacerbated DSS-induced colitis is associated with elevated NADPH oxidase expression in the colon.
Colitis
A novel danshensu derivative ameliorates experimental colitis by modulating NADPH oxidase 4-dependent NLRP3 inflammasome activation.
Colitis
NADPH oxidase deficient mice develop colitis and bacteremia upon infection with normally avirulent, TTSS-1- and TTSS-2-deficient Salmonella Typhimurium.
Colitis
Protective action of NADPH oxidase inhibitors and role of NADPH oxidase in pathogenesis of colon inflammation in mice.
Colitis
Regulation of murine intestinal inflammation by reactive metabolites of oxygen and nitrogen: divergent roles of superoxide and nitric oxide.
Colitis, Ulcerative
Apocynin Suppresses Lipopolysaccharide-Induced Inflammatory Responses Through the Inhibition of MAP Kinase Signaling Pathway in RAW264.7 Cells.
Colitis, Ulcerative
Influence of NADPH oxidase on inflammatory response in primary intestinal epithelial cells in patients with ulcerative colitis.
Colitis, Ulcerative
No association between a genetic variant of the p22PHOX component of NADPH oxidase C242T and ulcerative colitis.
Colitis-Associated Neoplasms
An ultralow dose of the NADPH oxidase inhibitor diphenyleneiodonium (DPI) is an economical and effective therapeutic agent for the treatment of colitis-associated colorectal cancer.
Colitis-Associated Neoplasms
Defective IL-23/IL-17 Axis Protects p47phox-/- Mice from Colon Cancer.
Colonic Neoplasms
Effects of iodonium-class flavin dehydrogenase inhibitors on growth, reactive oxygen production, cell cycle progression, NADPH oxidase 1 levels, and gene expression in human colon cancer cells and xenografts.
Colonic Neoplasms
Epidermal growth factor stimulates nuclear factor-?B activation and heme oxygenase-1 expression via c-Src, NADPH oxidase, PI3K, and Akt in human colon cancer cells.
Colonic Neoplasms
IGF-1 induces expression of zinc-finger protein 143 in colon cancer cells through phosphatidylinositide 3-kinase and reactive oxygen species.
Colonic Neoplasms
Interleukin-4 and interleukin-13 increase NADPH oxidase 1-related proliferation of human colon cancer cells.
Colonic Neoplasms
NADPH oxidase is involved in protein kinase CKII down-regulation-mediated senescence through elevation of the level of reactive oxygen species in human colon cancer cells.
Colonic Neoplasms
NADPH oxidase overexpression in human colon cancers and rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
Colonic Neoplasms
NADPH oxidase subunit, gp91(phox) homologue, preferentially expressed in human colon epithelial cells.
Colonic Neoplasms
NOX1 to NOX2 switch deactivates AMPK and induces invasive phenotype in colon cancer cells through overexpression of MMP-7.
Colorectal Neoplasms
15d-PGJ2 induces apoptosis by reactive oxygen species-mediated inactivation of Akt in leukemia and colorectal cancer cells and shows in vivo antitumor activity.
Colorectal Neoplasms
Expression of NOX Family Genes and Their Clinical Significance in Colorectal Cancer.
Colorectal Neoplasms
Suppressive effects of the NADPH oxidase inhibitor apocynin on intestinal tumorigenesis in obese KK-A(y) and Apc mutant Min mice.
Coma
Hypoglycemic neuronal death is triggered by glucose reperfusion and activation of neuronal NADPH oxidase.
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
A novel and unusual case of chronic granulomatous disease in a child with a homozygous 36-bp deletion in the CYBA gene (A22(0)) leading to the activation of a cryptic splice site in intron 4.
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Different unequal cross-over events between NCF1 and its pseudogenes in autosomal p47(phox)-deficient chronic granulomatous disease.
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Point mutation in the cytoplasmic domain of the neutrophil p22-phox cytochrome b subunit is associated with a nonfunctional NADPH oxidase and chronic granulomatous disease.
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Rare Duplication or Deletion of Exons 6, 7 and 8 in CYBB Leading to X-Linked Chronic Granulomatous Disease in Two Patients from Different Families.
Corneal Neovascularization
NADPH oxidase 2 plays a role in experimental corneal neovascularization.
Corneal Neovascularization
Wound Healing After Alkali Burn Injury of the Cornea Involves Nox4-Type NADPH Oxidase.
Coronary Artery Disease
C242T polymorphism of NADPH oxidase p22 PHOX gene and ischemic cerebrovascular disease in the Japanese population.
Coronary Artery Disease
C242T polymorphism of NADPH oxidase p22phox and recurrence of cardiovascular events in coronary artery disease.
Coronary Artery Disease
C242T polymorphism of NADPH oxidase p22phox gene reduces the risk of coronary artery disease in a random sample of Egyptian population.
Coronary Artery Disease
Endothelin-1 increases superoxide production in human coronary artery bypass grafts.
Coronary Artery Disease
NADPH oxidase activation played a critical role in the oxidative stress process in stable coronary artery disease.
Coronary Artery Disease
Relationship between NADPH oxidase p22phox C242T, PARP-1 Val762Ala polymorphisms, angiographically verified coronary artery disease and myocardial infarction in South Indian patients with type 2 diabetes mellitus.
Coronary Artery Disease
Relationship of the C242T p22phox gene polymorphism to angiographic coronary artery disease and endothelial function.
Coronary Artery Disease
Roles of NADPH oxidase and mitochondria in flow-induced vasodilation of human adipose arterioles: ROS-induced ROS release in coronary artery disease.
Coronary Artery Disease
The effect of p22-PHOX (CYBA) polymorphisms on premature coronary artery disease (? 40 years of age).
Coronary Artery Disease
[Role of NADPH oxidase in endothelial cell dysfunction induced by endothelial microparticles]
Coronary Disease
p22phox C242T Single-Nucleotide Polymorphism Inhibits Inflammatory Oxidative Damage to Endothelial Cells and Vessels.
Coronary Disease
Supplementation with Phycocyanobilin, Citrulline, Taurine, and Supranutritional Doses of Folic Acid and Biotin-Potential for Preventing or Slowing the Progression of Diabetic Complications.
COVID-19
Crosstalk of TLR4, vascular NADPH oxidase, and COVID-19 in diabetes: What are the potential implications?
COVID-19
Thrombotic complications of COVID-19 may reflect an upregulation of endothelial tissue factor expression that is contingent on activation of endosomal NADPH oxidase.
Coxsackievirus Infections
Superoxide Production by NADPH Oxidase Intensifies Macrophage Antiviral Responses during Diabetogenic Coxsackievirus Infection.
Crohn Disease
Dexamethasone and Tofacitinib suppress NADPH oxidase expression and alleviate very-early-onset ileocolitis in mice deficient in GSH peroxidase 1 and 2.
Crohn Disease
Escherichia coli LF82 differentially regulates ROS production and mucin expression in intestinal epithelial T84 cells: implication of NOX1.
Crohn Disease
NADPH oxidase complex and IBD candidate gene studies: identification of a rare variant in NCF2 that results in reduced binding to RAC2.
Crohn Disease
Subtractive screening reveals up-regulation of NADPH oxidase expression in Crohn's disease intestinal macrophages.
cystathionine beta-synthase deficiency
Cystathionine beta synthase deficiency induces catalase-mediated hydrogen peroxide detoxification in mice liver.
Cystic Fibrosis
Delayed association of the NADPH oxidase complex with macrophage vacuoles containing the opportunistic pathogen Burkholderia cenocepacia.
Cystic Fibrosis
Dysregulation in lung immunity - the protective and pathologic Th17 response in infection.
Cystic Fibrosis
Human Cystic Fibrosis Macrophages Have Defective Calcium-Dependent Protein Kinase C Activation of the NADPH Oxidase, an Effect Augmented by
Cystic Fibrosis
Small interfering peptide (siP) for in vivo examination of the developing lung interactonome.
Cystic Fibrosis
The role of chloride anion and CFTR in killing of Pseudomonas aeruginosa by normal and CF neutrophils.
Dehydration
A novel rice C2H2-type zinc finger protein, ZFP36, is a key player involved in abscisic acid-induced antioxidant defence and oxidative stress tolerance in rice.
Dehydration
Abscisic acid mediated differential growth responses of root and shoot of Vigna radiata (L.) Wilczek seedlings under water stress.
Dehydration
Drought-stimulated activity of plasma membrane nicotinamide adenine dinucleotide phosphate oxidase and its catalytic properties in rice.
Dehydration
Mechanical wounding-induced laticifer differentiation in rubber tree: An indicative role of dehydration, hydrogen peroxide, and jasmonates.
Delirium
Involvement of the NADPH Oxidase NOX2-Derived Brain Oxidative Stress in an Unusual Fatal Case of Cocaine-Related Neurotoxicity Associated With Excited Delirium Syndrome.
Delirium
The role of the NADPH oxidase derived brain oxidative stress in the cocaine-related death associated with excited delirium: A literature review.
Dementia, Vascular
Pitavastatin and 4'-hydroxy-3'-methoxyacetophenone (HMAP) reduce cognitive dysfunction in vascular dementia during experimental diabetes.
Demyelinating Diseases
Aging-Exacerbated Acute Axon and Myelin Injury Is Associated with Microglia-Derived Reactive Oxygen Species and Is Alleviated by the Generic Medication Indapamide.
Demyelinating Diseases
Microglial Hv1 proton channel promotes cuprizone-induced demyelination through oxidative damage.
Dermatitis
Severe Dermatitis Associated with Spontaneous Staphylococcus xylosus Infection in Rag(-/-)Tpl2(-/-) Mice.
Dermatitis, Atopic
NADPH oxidase inhibition rescues keratinocytes from elevated oxidative stress in a 2D atopic dermatitis and psoriasis model.
Diabetes Complications
Effects of Apocynin on Heart Muscle Oxidative Stress of Rats with Experimental Diabetes: Implications for Mitochondria.
Diabetes Complications
Modified kinetics of generation of reactive species in peripheral blood of patients with type 2 diabetes.
Diabetes Complications
NADPH Oxidase Inhibition: Preclinical and Clinical Studies in Diabetic Complications.
Diabetes Complications
NADPH oxidase: A membrane-bound enzyme and its inhibitors in diabetic complications.
Diabetes Complications
Treatment with NADPH oxidase inhibitor apocynin alleviates diabetic neuropathic pain in rats.
Diabetes Mellitus
Apocynin influence on oxidative stress and cardiac remodeling of spontaneously hypertensive rats with diabetes mellitus.
Diabetes Mellitus
Apoptosis signal regulating kinase-1 and NADPH oxidase mediate human amylin evoked redox stress and apoptosis in pancreatic beta-cells.
Diabetes Mellitus
Association of the -262C/T polymorphism in the catalase gene promoter and the C242T polymorphism of the NADPH oxidase P22phox gene with essential arterial hypertension in patients with diabetes mellitus type 2.
Diabetes Mellitus
Augmented NADPH oxidase activity and p22phox expression in monocytes underlie oxidative stress of patients with type 2 diabetes mellitus.
Diabetes Mellitus
Correction of aberrant NADPH oxidase activity in blood derived mononuclear cells from type II diabetes mellitus patients by a naturally fermented papaya preparation.
Diabetes Mellitus
Deletion of p47 ( phox ) attenuates the progression of diabetic nephropathy and reduces the severity of diabetes in the Akita mouse.
Diabetes Mellitus
Differential effects of diabetes on the expression of the gp91phox homologues nox1 and nox4.
Diabetes Mellitus
Monocyte NADPH oxidase subunit p22(phox) and inducible hemeoxygenase-1 gene expressions are increased in type II diabetic patients: relationship with oxidative stress.
Diabetes Mellitus
Priming of neutrophil oxidative burst in diabetes requires preassembly of the NADPH oxidase.
Diabetes Mellitus
Reactive Oxygen Species Can Provide Atheroprotection via NOX4-Dependent Inhibition of Inflammation and Vascular Remodeling.
Diabetes Mellitus
Relationship between NADPH oxidase p22phox C242T, PARP-1 Val762Ala polymorphisms, angiographically verified coronary artery disease and myocardial infarction in South Indian patients with type 2 diabetes mellitus.
Diabetes Mellitus
Selective Rac-1 inhibition protects from diabetes-induced vascular injury.
Diabetes Mellitus
The regulatory roles of NADPH oxidase, intra- and extra-cellular HSP70 in pancreatic islet function, dysfunction and diabetes.
Diabetes Mellitus
[Genetic risk factors for ischemic cerebrovascular disease--analysis on fifteen candidate prothrombotic gene polymorphisms in the Japanese population]
Diabetes Mellitus, Type 1
A physician-initiated double-blind, randomised, placebo-controlled, phase 2 study evaluating the efficacy and safety of inhibition of NADPH oxidase with the first-in-class Nox-1/4 inhibitor, GKT137831, in adults with type 1 diabetes and persistently elevated urinary albumin excretion: Protocol and statistical considerations.
Diabetes Mellitus, Type 1
Allelic variations in the CYBA gene of NADPH oxidase and risk of kidney complications in patients with type 1 diabetes.
Diabetes Mellitus, Type 1
Deficiency of rac1 blocks NADPH oxidase activation, inhibits endoplasmic reticulum stress, and reduces myocardial remodeling in a mouse model of type 1 diabetes.
Diabetes Mellitus, Type 1
Deletion of p47 ( phox ) attenuates the progression of diabetic nephropathy and reduces the severity of diabetes in the Akita mouse.
Diabetes Mellitus, Type 1
NADPH oxidase and PKC contribute to increased Na transport by the thick ascending limb during type 1 diabetes.
Diabetes Mellitus, Type 1
Superoxide production by macrophages and T cells is critical for the induction of autoreactivity and type 1 diabetes.
Diabetes Mellitus, Type 1
Targeting NADPH oxidase with a novel dual Nox1/Nox4 inhibitor attenuates renal pathology in type 1 diabetes.
Diabetes Mellitus, Type 1
Targeting the upregulation of reactive oxygen species subsequent to hyperglycemia prevents type 1 diabetic cardiomyopathy in mice.
Diabetes Mellitus, Type 1
The interleukin-1 receptor antagonist anakinra improves endothelial dysfunction in streptozotocin-induced diabetic rats.
Diabetes Mellitus, Type 1
The proinflammatory effects of macrophage-derived NADPH oxidase function in autoimmune diabetes.
Diabetes Mellitus, Type 1
The superoxide dismutase mimetic tempol blunts diabetes-induced upregulation of NADPH oxidase and endoplasmic reticulum stress in a rat model of diabetic nephropathy.
Diabetes Mellitus, Type 2
Association of the -262C/T polymorphism in the catalase gene promoter and the C242T polymorphism of the NADPH oxidase P22phox gene with essential arterial hypertension in patients with diabetes mellitus type 2.
Diabetes Mellitus, Type 2
Association of the C242T polymorphism in the NADPH oxidase p22 phox gene with carotid atherosclerosis in Slovenian patients with type 2 diabetes.
Diabetes Mellitus, Type 2
Augmented NADPH oxidase activity and p22phox expression in monocytes underlie oxidative stress of patients with type 2 diabetes mellitus.
Diabetes Mellitus, Type 2
Differential gene expression of NADPH oxidase (p22phox) and hemoxygenase-1 in patients with Type 2 diabetes and microangiopathy.
Diabetes Mellitus, Type 2
Modified kinetics of generation of reactive species in peripheral blood of patients with type 2 diabetes.
Diabetes Mellitus, Type 2
Modulation of mitochondria and NADPH oxidase function by the nitrate-nitrite-NO pathway in metabolic disease with focus on type 2 diabetes.
Diabetes Mellitus, Type 2
Monocyte NADPH oxidase subunit p22(phox) and inducible hemeoxygenase-1 gene expressions are increased in type II diabetic patients: relationship with oxidative stress.
Diabetes Mellitus, Type 2
NADPH oxidase inhibitor, apocynin, restores the impaired endothelial-dependent and -independent responses and scavenges superoxide anion in rats with type 2 diabetes complicated by NO dysfunction.
Diabetes Mellitus, Type 2
Relationship between NADPH oxidase p22phox C242T, PARP-1 Val762Ala polymorphisms, angiographically verified coronary artery disease and myocardial infarction in South Indian patients with type 2 diabetes mellitus.
Diabetes Mellitus, Type 2
Short-term intravenous insulin infusion is associated with reduced expression of NADPH oxidase p47(phox) subunit in monocytes from type 2 diabetes patients.
Diabetes Mellitus, Type 2
Superoxide and NADPH oxidase do not modulate skin blood flow in older exercising adults with and without type 2 diabetes.
Diabetes Mellitus, Type 2
The novel NADPH oxidase 4 inhibitor GLX351322 counteracts glucose intolerance in high-fat diet-treated C57BL/6 mice.
Diabetes Mellitus, Type 2
The novel NADPH oxidase 4 selective inhibitor GLX7013114 counteracts human islet cell death in vitro.
Diabetes Mellitus, Type 2
Tyrosine kinase-mediated activation of NADPH oxidase enhances proliferative capacity of diabetic vascular smooth muscle cells.
Diabetes Mellitus, Type 2
Unacylated ghrelin rescues endothelial progenitor cell function in individuals with type 2 diabetes.
Diabetic Angiopathies
Blockade of chronic high glucose-induced endothelial apoptosis by Sasa borealis bamboo extract.
Diabetic Angiopathies
Blockade of Renin-Angiotensin System Attenuates Advanced Glycation End Products-Mediated Signaling Pathways.
Diabetic Angiopathies
Endothelium-restricted endothelin-1 overexpression in type 1 diabetes worsens atherosclerosis and immune cell infiltration via NOX1.
Diabetic Angiopathies
Resveratrol Protects Vascular Endothelial Cells from High Glucose-Induced Apoptosis through Inhibition of NADPH Oxidase Activation-Driven Oxidative Stress.
Diabetic Angiopathies
Vascular Dysfunction in Streptozotocin-Induced Experimental Diabetes Strictly Depends on Insulin Deficiency.
Diabetic Cardiomyopathies
AT1 blockade prevents glucose-induced cardiac dysfunction in ventricular myocytes: role of the AT1 receptor and NADPH oxidase.
Diabetic Cardiomyopathies
Cannabinoid 1 receptor promotes cardiac dysfunction, oxidative stress, inflammation, and fibrosis in diabetic cardiomyopathy.
Diabetic Cardiomyopathies
Deficiency of rac1 blocks NADPH oxidase activation, inhibits endoplasmic reticulum stress, and reduces myocardial remodeling in a mouse model of type 1 diabetes.
Diabetic Cardiomyopathies
Long term liver specific glucokinase gene defect induced diabetic cardiomyopathy by up regulating NADPH oxidase and down regulating insulin receptor and p-AMPK.
Diabetic Cardiomyopathies
Metallothionein alleviates cardiac dysfunction in streptozotocin-induced diabetes: role of Ca2+ cycling proteins, NADPH oxidase, poly(ADP-Ribose) polymerase and myosin heavy chain isozyme.
Diabetic Cardiomyopathies
Nox4-derived reactive oxygen species mediate cardiomyocyte injury in early type 1 diabetes.
Diabetic Cardiomyopathies
Phosphoinositide 3-kinase (p110?) gene delivery limits diabetes-induced cardiac NADPH oxidase and cardiomyopathy in a mouse model with established diastolic dysfunction.
Diabetic Cardiomyopathies
ShengMai-San Attenuates Cardiac Remodeling in Diabetic Rats by Inhibiting NOX-Mediated Oxidative Stress.
Diabetic Cardiomyopathies
Therapeutic targeting of oxidative stress with coenzyme Q10 counteracts exaggerated diabetic cardiomyopathy in a mouse model of diabetes with diminished PI3K(p110?) signaling.
Diabetic Nephropathies
A novel pan-Nox inhibitor, APX-115, protects kidney injury in streptozotocin-induced diabetic mice: possible role of peroxisomal and mitochondrial biogenesis.
Diabetic Nephropathies
Allelic variations in the CYBA gene of NADPH oxidase and risk of kidney complications in patients with type 1 diabetes.
Diabetic Nephropathies
Argirein alleviates diabetic nephropathy through attenuating NADPH oxidase, Cx43, and PERK in renal tissue.
Diabetic Nephropathies
Chronic Running Exercise Alleviates Early Progression of Nephropathy with Upregulation of Nitric Oxide Synthases and Suppression of Glycation in Zucker Diabetic Rats.
Diabetic Nephropathies
Comment on: Thallas-Bonke et al. (2008) Inhibition of NADPH oxidase prevents advanced glycation end product-mediated damage in diabetic nephropathy through a protein kinase C-alpha-dependent pathway: Diabetes 57:460-469, 2008.
Diabetic Nephropathies
Critical role of Nox4-based NADPH oxidase in glucose-induced oxidative stress in the kidney - implications in type 2 diabetic nephropathy.
Diabetic Nephropathies
Differential contribution of Nox1, Nox2 and Nox4 to kidney vascular oxidative stress and endothelial dysfunction in obesity.
Diabetic Nephropathies
Effects of NADPH oxidase inhibitor on diabetic nephropathy in OLETF rats: the role of reducing oxidative stress in its protective property.
Diabetic Nephropathies
Ethyl pyruvate ameliorates albuminuria and glomerular injury in the animal model of diabetic nephropathy.
Diabetic Nephropathies
Genetic Targeting or Pharmacologic Inhibition of NADPH Oxidase Nox4 Provides Renoprotection in Long-Term Diabetic Nephropathy.
Diabetic Nephropathies
Glycated albumin activates NADPH oxidase in rat mesangial cells through up-regulation of p47phox.
Diabetic Nephropathies
Inhibition of NADPH oxidase prevents advanced glycation end product-mediated damage in diabetic nephropathy through a protein kinase C-alpha-dependent pathway.
Diabetic Nephropathies
Inhibition of renal gluconeogenesis contributes to hypoglycaemic action of NADPH oxidase inhibitor, apocynin.
Diabetic Nephropathies
Lysophosphatidic acid receptor 1 inhibitor, AM095, attenuates diabetic nephropathy in mice by downregulation of TLR4/NF-?B signaling and NADPH oxidase.
Diabetic Nephropathies
Mammalian target of rapamycin regulates Nox4-mediated podocyte depletion in diabetic renal injury.
Diabetic Nephropathies
Melatonin nephroprotective action in Zucker diabetic fatty rats involves its inhibitory effect on NADPH oxidase.
Diabetic Nephropathies
Metabolomics Reveals a Key Role for Fumarate in Mediating the Effects of NADPH Oxidase 4 in Diabetic Kidney Disease.
Diabetic Nephropathies
Microarray analysis of multiple candidate genes and associated plasma proteins for nephropathy secondary to type 2 diabetes among Chinese individuals.
Diabetic Nephropathies
mTORC2 Signaling Regulates Nox4-Induced Podocyte Depletion in Diabetes.
Diabetic Nephropathies
NADPH oxidase 4 promotes cisplatin-induced acute kidney injury via ROS-mediated programmed cell death and inflammation.
Diabetic Nephropathies
NADPH Oxidase Nox5 Accelerates Renal Injury in Diabetic Nephropathy.
Diabetic Nephropathies
NADPH oxidase p22phox C242T polymorphism is associated with macroalbuminuria in diabetic patients: A meta-analysis.
Diabetic Nephropathies
Normalizing NADPH Oxidase Contributes to Attenuating Diabetic Nephropathy by the Dual Endothelin Receptor Antagonist CPU0213 in Rats.
Diabetic Nephropathies
Preservation of kidney function with combined inhibition of NADPH oxidase and angiotensin-converting enzyme in diabetic nephropathy.
Diabetic Nephropathies
Regulation of NADPH oxidase activity is associated with miRNA-25-mediated NOX4 expression in experimental diabetic nephropathy.
Diabetic Nephropathies
Regulation of transforming growth factor beta 1 gene expression by dihydropteridine reductase in kidney 293T cells.
Diabetic Nephropathies
Renoprotective effects of a novel Nox1/4 inhibitor in a mouse model of type 2 diabetes.
Diabetic Nephropathies
ROS generation by nonphagocytic NADPH oxidase: potential relevance in diabetic nephropathy.
Diabetic Nephropathies
Schizandrin prevents damage of murine mesangial cells via blocking NADPH oxidase-induced ROS signaling in high glucose.
Diabetic Nephropathies
Targeting of Rho kinase ameliorates impairment of diabetic endothelial function in intrarenal artery.
Diabetic Nephropathies
The mTOR promotes oxidative stress-induced apoptosis of mesangial cells in diabetic nephropathy.
Diabetic Nephropathies
The role of adrenomedullin in the renal NADPH oxidase and (pro)renin in diabetic mice.
Diabetic Nephropathies
The superoxide dismutase mimetic tempol blunts diabetes-induced upregulation of NADPH oxidase and endoplasmic reticulum stress in a rat model of diabetic nephropathy.
Diabetic Neuropathies
Curcumin ameliorated diabetic neuropathy partially by inhibition of NADPH oxidase mediating oxidative stress in the spinal cord.
Diabetic Retinopathy
A lipidomic screen of hyperglycemia-treated HRECs links 12/15-Lipoxygenase to microvascular dysfunction during diabetic retinopathy via NADPH oxidase.
Diabetic Retinopathy
Activation of nicotinamide adenine dinucleotide phosphate (reduced form) oxidase by advanced glycation end products links oxidative stress to altered retinal vascular endothelial growth factor expression.
Diabetic Retinopathy
Apocynin ameliorates NADPH oxidase 4 (NOX4) induced oxidative damage in the hypoxic human retinal Müller cells and diabetic rat retina.
Diabetic Retinopathy
Diabetic retinopathy and transcriptional regulation of a small molecular weight G-Protein, Rac1.
Diabetic Retinopathy
Diabetic retinopathy: Focus on NADPH oxidase and its potential as therapeutic target.
Diabetic Retinopathy
NADPH Oxidase versus Mitochondria-Derived ROS in Glucose-Induced Apoptosis of Pericytes in Early Diabetic Retinopathy.
Diabetic Retinopathy
Pigment epithelium-derived factor inhibits advanced glycation end products-induced retinal vascular permeability.
Diabetic Retinopathy
Pigment epithelium-derived factor inhibits retinal microvascular dysfunction induced by 12/15-lipoxygenase-derived eicosanoids.
Diabetic Retinopathy
Role of endoplasmic reticulum stress in 12/15-lipoxygenase-induced retinal microvascular dysfunction in a mouse model of diabetic retinopathy.
Diabetic Retinopathy
Role of NADPH oxidase and Stat3 in statin-mediated protection against diabetic retinopathy.
Disorders of Excessive Somnolence
NADPH oxidase mediates hypersomnolence and brain oxidative injury in a murine model of sleep apnea.
Duodenal Ulcer
Genetic variant of the p22PHOX component of NADPH oxidase C242T and the incidence of gastric cancer in Japan.
Dyslipidemias
Simvastatin Attenuates Oxidative Stress, NF-?B Activation, and Artery Calcification in LDLR-/- Mice Fed with High Fat Diet via Down-regulation of Tumor Necrosis Factor-? and TNF Receptor 1.
Ectodermal Dysplasia
Essential role of nuclear factor-kappaB for NADPH oxidase activity in normal and anhidrotic ectodermal dysplasia leukocytes.
Ectodermal Dysplasia
Nuclear factor-{kappa}B is not essential for NADPH oxidase activity in neutrophils from anhidrotic ectodermal dysplasia patients.
Ehrlichiosis
Anaplasma phagocytophilum modulates gp91phox gene expression through altered interferon regulatory factor 1 and PU.1 levels and binding of CCAAT displacement protein.
Ehrlichiosis
Essential role for humoral immunity during Ehrlichia infection in immunocompetent mice.
Encephalomyelitis
A leading role for NADPH oxidase in an in-vitro study of experimental autoimmune encephalomyelitis.
Encephalomyelitis
Advanced intercross line mapping suggests that ncf1 (ean6) regulates severity in an animal model of guillain-barre syndrome.
Encephalomyelitis
Experimental autoimmune encephalomyelitis and age-related correlations of NADPH oxidase, MMP-9, and cell adhesion molecules: The increased disease severity and blood-brain barrier permeability in middle-aged mice.
Encephalomyelitis
Expression and activation of matrix metalloproteinase-9 and NADPH oxidase in tissues and plasma of experimental autoimmune encephalomyelitis in mice.
Encephalomyelitis
Inhibition of NADPH oxidase activation reduces EAE-induced white matter damage in mice.
Encephalomyelitis
Oxidative tissue injury in multiple sclerosis is only partly reflected in experimental disease models.
Encephalomyelitis
Superoxide prevents nitric oxide-mediated suppression of helper T lymphocytes: decreased autoimmune encephalomyelitis in nicotinamide adenine dinucleotide phosphate oxidase knockout mice.
Encephalomyelitis, Autoimmune, Experimental
A leading role for NADPH oxidase in an in-vitro study of experimental autoimmune encephalomyelitis.
Encephalomyelitis, Autoimmune, Experimental
Experimental autoimmune encephalomyelitis and age-related correlations of NADPH oxidase, MMP-9, and cell adhesion molecules: The increased disease severity and blood-brain barrier permeability in middle-aged mice.
Encephalomyelitis, Autoimmune, Experimental
Expression and activation of matrix metalloproteinase-9 and NADPH oxidase in tissues and plasma of experimental autoimmune encephalomyelitis in mice.
Encephalomyelitis, Autoimmune, Experimental
Inhibition of NADPH oxidase activation reduces EAE-induced white matter damage in mice.
Encephalomyelitis, Autoimmune, Experimental
Superoxide prevents nitric oxide-mediated suppression of helper T lymphocytes: decreased autoimmune encephalomyelitis in nicotinamide adenine dinucleotide phosphate oxidase knockout mice.
Endometrial Neoplasms
?-Terthienylmethanol, isolated from Eclipta prostrata, induces apoptosis by generating reactive oxygen species via NADPH oxidase in human endometrial cancer cells.
Endometrial Neoplasms
Endogenous production of reactive oxygen species by the NADPH oxidase complexes is a determinant of ?-glutamyltransferase expression.
Endotoxemia
Anthocyanins protect the gastrointestinal tract from high fat diet-induced alterations in redox signaling, barrier integrity and dysbiosis.
Endotoxemia
Effect of natural antioxidants and apocynin on LPS-induced endotoxemia in rabbit.
Eosinophilia
Nonhematopoietic NADPH oxidase regulation of lung eosinophilia and airway hyperresponsiveness in experimentally induced asthma.
Eosinophilia
Pivotal Advance: Eosinophilia in the MES rat strain is caused by a loss-of-function mutation in the gene for cytochrome b(-245), alpha polypeptide (Cyba).
Epilepsy
NADPH oxidase activation and 4-hydroxy-2-nonenal/aquaporin-4 adducts as possible new players in oxidative neuronal damage presents in drug-resistant epilepsy.
Epilepsy
Reactive oxygen species generated by NADPH oxidase are involved in neurodegeneration in the pilocarpine model of temporal lobe epilepsy.
Epilepsy
Status epilepticus results in persistent overproduction of reactive oxygen species, inhibition of which is neuroprotective.
Epilepsy, Temporal Lobe
Reactive oxygen species generated by NADPH oxidase are involved in neurodegeneration in the pilocarpine model of temporal lobe epilepsy.
Erectile Dysfunction
Comparison of sildenafil with strontium fructose diphosphate in improving erectile dysfunction against upregulated cavernosal NADPH oxidase, protein kinase C?, and endothelin system in diabetic rats.
Erectile Dysfunction
Constitutive NOS uncoupling and NADPH oxidase upregulation in the penis of type 2 diabetic men with erectile dysfunction.
Erectile Dysfunction
Effect of sildenafil citrate and a nitric oxide donating sildenafil derivative, NCX 911, on cavernosal relaxation and superoxide formation in hypercholesterolaemic rabbits.
Erectile Dysfunction
NADPH Oxidase Activation: A Mechanism of Erectile Dysfunction in a Rat Model of Sleep Apnea.
Erectile Dysfunction
NADPH oxidase activation: a mechanism of hypertension-associated erectile dysfunction.
Erectile Dysfunction
Reactive oxygen species and erectile dysfunction: possible role of NADPH oxidase.
Erectile Dysfunction
Sildenafil inhibits the up-regulation of phosphodiesterase type 5 elicited with nicotine and tumour necrosis factor-alpha in cavernosal vascular smooth muscle cells: mediation by superoxide.
Erectile Dysfunction
Superoxide Anion Production by NADPH Oxidase Plays a Major Role in Erectile Dysfunction in Middle-Aged Rats: Prevention by Antioxidant Therapy.
Erectile Dysfunction
The arachidonic acid-binding protein S100A8/A9 promotes NADPH oxidase activation by interaction with p67phox and Rac-2.
Esophageal Squamous Cell Carcinoma
[Interaction of polymorphisms of PPAR-?2 gene -C34G and NADPH oxidase subunit p22phox gene -C242T with Helicobacter pylori infection in esophageal squamous cell carcinoma].
Essential Hypertension
Hemizygosity at the NCF1 Gene in Patients with Williams-Beuren Syndrome Decreases Their Risk of Hypertension.
Essential Hypertension
Inhibition of the ROS-EGFR Pathway Mediates the Protective Action of Nox1/4 Inhibitor GKT137831 against Hypertensive Cardiac Hypertrophy via Suppressing Cardiac Inflammation and Activation of Akt and ERK1/2.
Essential Hypertension
NADPH oxidase, superoxide overproduction and nitric oxide bioavailability in essential hypertension.
Essential Hypertension
Regulation of the superoxide-forming NADPH oxidase of human neutrophils is not altered in essential hypertension.
Essential Hypertension
The C242T CYBA polymorphism of NADPH oxidase is associated with essential hypertension.
Fatty Liver
AMP-activated protein kinase activation and NADPH oxidase inhibition by inorganic nitrate and nitrite prevent liver steatosis.
Fatty Liver
Apocynin administration prevents the changes induced by a fructose-rich diet on rat liver metabolism and the antioxidant system.
Fatty Liver
Association between the CYBA and NOX4 genes of NADPH oxidase and its relationship with metabolic syndrome in non-alcoholic fatty liver disease in Brazilian population.
Fatty Liver
NADPH oxidase is not an essential mediator of oxidative stress or liver injury in murine MCD diet-induced steatohepatitis.
Fatty Liver
The Presence of p47phox in Liver Parenchymal Cells is a Key Mediator in the Pathogenesis of Alcoholic Liver Steatosis.
Fetal Alcohol Spectrum Disorders
The role of NADPH oxidase in a mouse model of fetal alcohol syndrome.
Fibrosarcoma
Involvement of oxidants and oxidant-generating enzyme(s) in tumour-necrosis-factor-alpha-mediated apoptosis: role for lipoxygenase pathway but not mitochondrial respiratory chain.
Fibrosarcoma
Superoxide plays critical roles in electrotaxis of fibrosarcoma cells via activation of ERK and reorganization of cytoskeleton.
Fragile X Syndrome
Design of dual inhibitors of ROCK-I and NOX2 as potential leads for the treatment of neuroinflammation associated with various neurological diseases including autism spectrum disorder.
Galactosemias
Impaired NADPH oxidase activity in peripheral blood lymphocytes of galactosemia patients.
Gastritis
Association of polymorphism of the p22PHOX component of NADPH oxidase in gastroduodenal diseases in Japan.
Gastrointestinal Neoplasms
Dual Oxidase2 and pancreatic adenocarcinoma: IFN-?-mediated dual oxidase2 overexpression results in H2O2-induced, ERKassociated up-regulation of HIF-1? and VEGF-A.
Genetic Diseases, Inborn
Interferon gamma-1b. A review of its pharmacology and therapeutic potential in chronic granulomatous disease.
Genetic Diseases, Inborn
Molecular analysis of X-linked chronic granulomatous disease in five unrelated Korean patients.
Genetic Diseases, Inborn
Rapid determination of chimerism status using dihydrorhodamine assay in a patient with X-linked chronic granulomatous disease following hematopoietic stem cell transplantation.
Genetic Diseases, Inborn
Renal transplantation in a patient with chronic granulomatous disease: case report.
Genetic Diseases, Inborn
Successful renal transplantation in patients with chronic granulomatous disease.
Genetic Diseases, Inborn
The p47(phox-/-) mouse model of chronic granulomatous disease has normal granuloma formation and cytokine responses to Mycobacterium avium and Schistosoma mansoni eggs.
Genetic Diseases, Inborn
Thymosin ?4 promotes autophagy and repair via HIF-1? stabilization in chronic granulomatous disease.
Genetic Diseases, Inborn
Virulence of catalase-deficient aspergillus nidulans in p47(phox)-/- mice. Implications for fungal pathogenicity and host defense in chronic granulomatous disease.
Genetic Diseases, Inborn
[Chronic granulomatous disease: pathogenesis and therapy of associated fungal infections].
Gilbert Disease
NAPDH oxidase mediates glucolipotoxicity-induced beta cell dysfunction - Clinical implications.
Glaucoma
Extracellular Signal-Regulated Kinase 1/2 Pathway Is Insufficiently Involved in the Neuroprotective Effect by Hydrogen Sulfide Supplement in Experimental Glaucoma.
Glioblastoma
Lentivirus-mediated Nox4 shRNA invasion and angiogenesis and enhances radiosensitivity in human glioblastoma.
Glioblastoma
NADPH oxidase subunit 4 mediates cycling hypoxia-promoted radiation resistance in glioblastoma multiforme.
Glioblastoma
NADPH oxidase subunit 4-mediated reactive oxygen species contribute to cycling hypoxia-promoted tumor progression in glioblastoma multiforme.
Glioblastoma
Nox4 redox regulation of PTP1B contributes to the proliferation and migration of glioblastoma cells by modulating tyrosine phosphorylation of coronin-1C.
Glioma
Differential suitability of reactive oxygen species and the role of glutathione in regulating paradoxical behavior in gliomas: A mathematical perspective.
Glioma
Enhanced expression of NADPH oxidase Nox4 in human gliomas and its roles in cell proliferation and survival.
Glioma
Mechanisms of tumor necrosis factor-alpha-induced interleukin-6 synthesis in glioma cells.
Glioma
Nicotine- and tar-free cigarette smoke extract induces cell injury via intracellular Ca2+-dependent subtype-specific protein kinase C activation.
Glomerulonephritis
Addition of the Antioxidant Probucol to Angiotensin II Type I Receptor Antagonist Arrests Progressive Mesangioproliferative Glomerulonephritis in the Rat.
Glomerulonephritis
Peroxisome proliferator-activated receptor alpha protects against glomerulonephritis induced by long-term exposure to the plasticizer di-(2-ethylhexyl)phthalate.
Glomerulonephritis
Polymorphisms in NADPH oxidase CYBA gene modify the risk of ESRD in patients with chronic glomerulonephritis.
Glucose Intolerance
Effect of spirulina and silicon-enriched spirulina on metabolic syndrome features, oxidative stress and mitochondrial activity in Zucker fatty rats.
Glucose Intolerance
Spirulina platensis and silicon-enriched spirulina equally improve glucose tolerance and decrease the enzymatic activity of hepatic NADPH oxidase in obesogenic diet-fed rats.
glucose-6-phosphate dehydrogenase (nadp+) deficiency
Association of glucose-6-phosphate dehydrogenase deficiency and X-linked chronic granulomatous disease in a child with anemia and recurrent infections.
glucose-6-phosphate dehydrogenase (nadp+) deficiency
Expanding the clinical and genetic spectrum of G6PD deficiency: The occurrence of BCGitis and novel missense mutation.
glucose-6-phosphate dehydrogenase (nadp+) deficiency
Glucose-6 phosphate dehydrogenase deficiency decreases the vascular response to angiotensin II.
Glucosephosphate Dehydrogenase Deficiency
Association of glucose-6-phosphate dehydrogenase deficiency and X-linked chronic granulomatous disease in a child with anemia and recurrent infections.
Glucosephosphate Dehydrogenase Deficiency
Expanding the clinical and genetic spectrum of G6PD deficiency: The occurrence of BCGitis and novel missense mutation.
Glucosephosphate Dehydrogenase Deficiency
Glucose-6 phosphate dehydrogenase deficiency decreases the vascular response to angiotensin II.
Glycogen Storage Disease
NADPH oxidase activity and chemotaxis by neutrophils in two patients with glycogen storage disease type Ib treated with recombinant human granulocyte-monocyte colony-stimulating factor.
Goiter
A Novel Missense Mutation (I26M) in DUOXA2 Causing Congenital Goiter Hypothyroidism Impairs NADPH Oxidase Activity but Not Protein Expression.
Goiter
Ca(2+)/nicotinamide adenine dinucleotide phosphate-dependent H(2)O(2) generation is inhibited by iodide in human thyroids.
Granuloma
Adaptive immune defects against glycoantigens in chronic granulomatous disease via dysregulated nitric oxide production.
Granuloma
B subset cells in patients with chronic granulomatous disease in a Mexican population.
Granuloma
Bacillus calmette-guerin infection in NADPH oxidase deficiency: defective mycobacterial sequestration and granuloma formation.
Granuloma
Induction of Pulmonary Granuloma Formation by Propionibacterium acnes is regulated by MyD88 and Nox2.
Granuloma
Rasamsonia sp: An emerging infection amongst chronic granulomatous disease patients. A case of disseminated infection by a putatively novel Rasamsonia argillacea species complex involving the heart.
Granuloma
Safety and effectiveness of long-term interferon gamma therapy in patients with chronic granulomatous disease.
Granulomatous Disease, Chronic
A 1.1-kb duplication in the p67-phox gene causes chronic granulomatous disease.
Granulomatous Disease, Chronic
A C126R de novo Mutation in CYBB Leads to X-linked Chronic Granulomatous Disease With Recurrent Pneumonia and BCGitis.
Granulomatous Disease, Chronic
A founder effect for p47(phox)Trp193Ter chronic granulomatous disease in Kavkazi Jews.
Granulomatous Disease, Chronic
A functional NADPH oxidase prevents caspase involvement in the clearance of phagocytic neutrophils.
Granulomatous Disease, Chronic
A mutation located at the 5' splice junction sequence of intron 3 in the p67phox gene causes the lack of p67phox mRNA in a patient with chronic granulomatous disease.
Granulomatous Disease, Chronic
A new genetic subgroup of chronic granulomatous disease with autosomal recessive mutations in p40 phox and selective defects in neutrophil NADPH oxidase activity.
Granulomatous Disease, Chronic
A novel and unusual case of chronic granulomatous disease in a child with a homozygous 36-bp deletion in the CYBA gene (A22(0)) leading to the activation of a cryptic splice site in intron 4.
Granulomatous Disease, Chronic
A novel role for the beta 2 integrin CD11b/CD18 in neutrophil apoptosis: a homeostatic mechanism in inflammation.
Granulomatous Disease, Chronic
A novel variant in the neutrophil cytosolic factor 2 (NCF2) gene results in severe disseminated BCG infectious disease: A clinical report and literature review.
Granulomatous Disease, Chronic
A simple approach for the analysis of intracellular movement of oxidant-producing intracellular compartments in living human neutrophils.
Granulomatous Disease, Chronic
A variant of chronic granulomatous disease: deficient oxidative metabolism due to a low-affinity NADPH oxidase.
Granulomatous Disease, Chronic
Abnormal activation of H+ conductance in NADPH oxidase-defective neutrophils.
Granulomatous Disease, Chronic
Activation of H+ conductance in neutrophils requires assembly of components of the respiratory burst oxidase but not its redox function.
Granulomatous Disease, Chronic
Activation of NADPH oxidase required for macrophage-mediated oxidation of low-density lipoprotein.
Granulomatous Disease, Chronic
Adaptive immune defects against glycoantigens in chronic granulomatous disease via dysregulated nitric oxide production.
Granulomatous Disease, Chronic
Adenosine A(2A) receptor activation limits chronic granulomatous disease-induced hyperinflammation.
Granulomatous Disease, Chronic
Altered Pattern of Naïve and Memory B cells and B1 Cells in Patients with Chronic Granulomatous Disease.
Granulomatous Disease, Chronic
An efferocytosis-induced, IL-4-dependent macrophage-iNKT cell circuit suppresses sterile inflammation and is defective in murine CGD.
Granulomatous Disease, Chronic
Analysis of Chronic Granulomatous Disease in the Kavkazi Population in Israel Reveals Phenotypic Heterogeneity in Patients with the Same NCF1 mutation (c.579G>A).
Granulomatous Disease, Chronic
Approach to Molecular Diagnosis of Chronic Granulomatous Disease (CGD): an Experience from a Large Cohort of 90 Indian Patients.
Granulomatous Disease, Chronic
Aspergillus nidulans infection in chronic granulomatous disease.
Granulomatous Disease, Chronic
Assessment of the contribution of the cytochrome b moiety of the NADPH oxidase to the transmembrane H+ conductance of leukocytes.
Granulomatous Disease, Chronic
Association of glucose-6-phosphate dehydrogenase deficiency and X-linked chronic granulomatous disease in a child with anemia and recurrent infections.
Granulomatous Disease, Chronic
Autosomal recessive chronic granulomatous disease with absence of the 67-kD cytosolic NADPH oxidase component: identification of mutation and detection of carriers.
Granulomatous Disease, Chronic
B subset cells in patients with chronic granulomatous disease in a Mexican population.
Granulomatous Disease, Chronic
beta-amyloid activates the O-2 forming NADPH oxidase in microglia, monocytes, and neutrophils. A possible inflammatory mechanism of neuronal damage in Alzheimer's disease.
Granulomatous Disease, Chronic
Bioluminescence imaging of NADPH oxidase activity in different animal models.
Granulomatous Disease, Chronic
Catalase negative Staphylococcus aureus retain virulence in mouse model of chronic granulomatous disease.
Granulomatous Disease, Chronic
CD40/CD40L expression in leukocytes from chronic granulomatous disease patients.
Granulomatous Disease, Chronic
Cell-free assays: the reductionist approach to the study of NADPH oxidase assembly, or "all you wanted to know about cell-free assays but did not dare to ask".
Granulomatous Disease, Chronic
Cell-free NADPH oxidase activation assays: "in vitro veritas".
Granulomatous Disease, Chronic
Cell-Free NADPH Oxidase Activation Assays: A Triumph of Reductionism.
Granulomatous Disease, Chronic
Characterization of nitric oxide consumption pathways by normal, chronic granulomatous disease and myeloperoxidase-deficient human neutrophils.
Granulomatous Disease, Chronic
Characterization of six novel mutations in the CYBB gene leading to different sub-types of X-linked chronic granulomatous disease.
Granulomatous Disease, Chronic
Characterization of the 47-kilodalton autosomal chronic granulomatous disease protein: tissue-specific expression and transcriptional control by retinoic acid.
Granulomatous Disease, Chronic
Chronic granulomatous disease due to granulocytes with abnormal NADPH oxidase activity and deficient cytochrome-b.
Granulomatous Disease, Chronic
Chronic Granulomatous Disease Due to Neutrophil Cytosolic Factor (NCF2) Gene Mutations in Three Unrelated Families.
Granulomatous Disease, Chronic
Chronic granulomatous disease, the McLeod phenotype and the contiguous gene deletion syndrome-a review.
Granulomatous Disease, Chronic
Chronic Granulomatous Disease: A 25-Year Patient Registry Based on a Multistep Diagnostic Procedure, from the Referral Center for Primary Immunodeficiencies in Greece.
Granulomatous Disease, Chronic
Chronic granulomatous disease: Clinical, molecular, and therapeutic aspects.
Granulomatous Disease, Chronic
Chronic granulomatous disease: why an inflammatory disease?
Granulomatous Disease, Chronic
Clinical and Immunological Characteristics of 63 Patients with Chronic Granulomatous Disease: Hacettepe Experience.
Granulomatous Disease, Chronic
Clinical and molecular features of 38 children with chronic granulomatous disease in mainland china.
Granulomatous Disease, Chronic
Clinical Manifestations of Disease in X-Linked Carriers of Chronic Granulomatous Disease.
Granulomatous Disease, Chronic
Clinical, Functional and Genetic Analysis of Twenty-Four Patients with Chronic Granulomatous Disease - Identification of Eight Novel Mutations in CYBB and NCF2 Genes.
Granulomatous Disease, Chronic
Clinical, functional and genetic characterization of Sixteen Patients Suffering from Chronic Granulomatous Disease variants - Identification of Eleven Novel Mutations in CYBB.
Granulomatous Disease, Chronic
Clinical, Immunological, and Molecular Findings of Patients with p47(phox) Defect Chronic Granulomatous Disease (CGD) in Indian Families.
Granulomatous Disease, Chronic
Cloning of the cDNA and functional expression of the 47-kilodalton cytosolic component of human neutrophil respiratory burst oxidase.
Granulomatous Disease, Chronic
Complementation of NADPH oxidase in p67-phox-deficient CGD patients p67-phox/p40-phox interaction.
Granulomatous Disease, Chronic
Conventional versus interferon-gamma therapy in chronic granulomatous disease.
Granulomatous Disease, Chronic
Copy number variations due to large genomic deletion in x-linked chronic granulomatous disease.
Granulomatous Disease, Chronic
Coregulation of NADPH oxidase activation and phosphorylation of a 48-kD protein(s) by a cytosolic factor defective in autosomal recessive chronic granulomatous disease.
Granulomatous Disease, Chronic
Cytochrome b558-negative, autosomal recessive chronic granulomatous disease: two new mutations in the cytochrome b558 light chain of the NADPH oxidase (p22-phox).
Granulomatous Disease, Chronic
Cytokine-mediated induction of MHC class II in human neutrophils is dependent on NADPH oxidase activity.
Granulomatous Disease, Chronic
Cytosolic phox proteins interact with and regulate the assembly of coronin in neutrophils.
Granulomatous Disease, Chronic
Decreased neural precursor cell pool in NADPH oxidase 2-deficiency: From mouse brain to neural differentiation of patient derived iPSC.
Granulomatous Disease, Chronic
Defective priming of the phagocyte oxidative burst in a child with recurrent intracellular infections.
Granulomatous Disease, Chronic
Deficiency of NADPH oxidase activity in chronic granulomatous disease.
Granulomatous Disease, Chronic
Deficiency of p67phox, p47phox or gp91phox in chronic granulomatous disease does not impair leucocyte chemotaxis or motility.
Granulomatous Disease, Chronic
Delineation of the phagocyte NADPH oxidase through studies of chronic granulomatous diseases of childhood.
Granulomatous Disease, Chronic
Derivation and Functional Analysis of Patient Specific Induced Pluripotent Stem Cells as an In Vitro Model of Chronic Granulomatous Disease.
Granulomatous Disease, Chronic
Detection of gp91-phox precursor protein in B-cell lines from patients with X-linked chronic granulomatous disease as an indicator for mutations impairing cytochrome b558 biosynthesis.
Granulomatous Disease, Chronic
Detection of non-DeltaGT NCF-1 mutations in chronic granulomatous disease.
Granulomatous Disease, Chronic
Different unequal cross-over events between NCF1 and its pseudogenes in autosomal p47(phox)-deficient chronic granulomatous disease.
Granulomatous Disease, Chronic
Differential expression and regulation of hsp70 and hsp90 by phorbol esters and heat shock.
Granulomatous Disease, Chronic
Diverse stimuli engage different neutrophil extracellular trap pathways.
Granulomatous Disease, Chronic
Dysregulation in lung immunity - the protective and pathologic Th17 response in infection.
Granulomatous Disease, Chronic
Effect of amphotericin B and micafungin combination on survival, histopathology, and fungal burden in experimental aspergillosis in the p47phox-/- mouse model of chronic granulomatous disease.
Granulomatous Disease, Chronic
Effects of platinum and palladium ions on the production and reactivity of neutrophil-derived reactive oxygen species.
Granulomatous Disease, Chronic
Enhanced cutaneous inflammatory reactions to Aspergillus fumigatus in a murine model of chronic granulomatous disease.
Granulomatous Disease, Chronic
Enterobacter cloacae pyomyositis complicating chronic granulomatous disease and review of gram-negative bacilli pyomyositis.
Granulomatous Disease, Chronic
EROS/CYBC1 mutations: Decreased NADPH oxidase function and chronic granulomatous disease.
Granulomatous Disease, Chronic
Exon skipping in CYBB mRNA and skewed inactivation of X chromosome cause late-onset chronic granulomatous disease.
Granulomatous Disease, Chronic
Fas and FasL expression in leukocytes from chronic granulomatous disease patients.
Granulomatous Disease, Chronic
Flow cytometric analysis of the granulocyte respiratory burst: a comparison study of fluorescent probes.
Granulomatous Disease, Chronic
Functional analysis of NADPH oxidase in granulocytic cells expressing a delta488-497 gp91(phox) deletion mutant.
Granulomatous Disease, Chronic
Functional analysis of two-amino acid substitutions in gp91 phox in a patient with X-linked flavocytochrome b558-positive chronic granulomatous disease by means of transgenic PLB-985 cells.
Granulomatous Disease, Chronic
Functional Restoration of gp91phox-Oxidase Activity by BAC Transgenesis and Gene Targeting in X-linked Chronic Granulomatous Disease iPSCs.
Granulomatous Disease, Chronic
Gene transfer to primary chronic granulomatous disease monocytes.
Granulomatous Disease, Chronic
Generation of X-CGD cells for vector evaluation from healthy donor CD34(+) HSCs by shRNA-mediated knock down of gp91(phox).
Granulomatous Disease, Chronic
Genetic studies of three Japanese patients with p22-phox-deficient chronic granulomatous disease: detection of a possible common mutant CYBA allele in Japan and a genotype-phenotype correlation in these patients.
Granulomatous Disease, Chronic
Genetic variants of chronic granulomatous disease: prevalence of deficiencies of two cytosolic components of the NADPH oxidase system.
Granulomatous Disease, Chronic
Genetic, biochemical, and clinical features of chronic granulomatous disease.
Granulomatous Disease, Chronic
Genetical analysis of all Danish patients diagnosed with chronic granulomatous disease.
Granulomatous Disease, Chronic
Granulocyte colony-stimulating factor prior to nonmyeloablative irradiation decreases murine host hematopoietic stem cell function and increases engraftment of donor marrow cells.
Granulomatous Disease, Chronic
Haploidentical stem cell transplantation in a boy with chronic granulomatous disease.
Granulomatous Disease, Chronic
Haploinsufficiency of NADPH Oxidase Subunit Neutrophil Cytosolic Factor 2 Is Sufficient to Accelerate Full-Blown Lupus in NZM 2328 Mice.
Granulomatous Disease, Chronic
Health-Related Quality of Life and Emotional Health in X-Linked Carriers of Chronic Granulomatous Disease in the United Kingdom.
Granulomatous Disease, Chronic
Hematopoietic Tumors in a Mouse Model of X-linked Chronic Granulomatous Disease after Lentiviral Vector-Mediated Gene Therapy.
Granulomatous Disease, Chronic
Human polymorphonuclear leukocytes inhibit Aspergillus fumigatus conidial growth by lactoferrin-mediated iron depletion.
Granulomatous Disease, Chronic
Hyper-responsive Toll-like receptor 7 and 9 activation in NADPH oxidase-deficient B lymphoblasts.
Granulomatous Disease, Chronic
Hypochlorous acid regulates neutrophil extracellular trap release in humans.
Granulomatous Disease, Chronic
Identification of a thermolabile component of the human neutrophil NADPH oxidase. A model for chronic granulomatous disease caused by deficiency of the p67-phox cytosolic component.
Granulomatous Disease, Chronic
Identification of the defective NADPH-oxidase component in chronic granulomatous disease: a study of 57 European families.
Granulomatous Disease, Chronic
Impaired macrophage function following bacterial stimulation in chronic granulomatous disease.
Granulomatous Disease, Chronic
Infections associated with chronic granulomatous disease: linking genetics to phenotypic expression.
Granulomatous Disease, Chronic
Inflammasome activation in NADPH oxidase defective mononuclear phagocytes from patients with chronic granulomatous disease.
Granulomatous Disease, Chronic
Inflammatory Manifestations in Children with Chronic Granulomatous Disease.
Granulomatous Disease, Chronic
Inherited p40phox deficiency differs from classic chronic granulomatous disease.
Granulomatous Disease, Chronic
Inhibition of spontaneous neutrophil apoptosis by parabutoporin acts independently of NADPH oxidase inhibition but by lipid raft-dependent stimulation of Akt.
Granulomatous Disease, Chronic
Interferon gamma-1b. A review of its pharmacology and therapeutic potential in chronic granulomatous disease.
Granulomatous Disease, Chronic
Interferon-gamma improves splicing efficiency of CYBB gene transcripts in an interferon-responsive variant of chronic granulomatous disease due to a splice site consensus region mutation.
Granulomatous Disease, Chronic
Intersecting Stories of the Phagocyte NADPH Oxidase and Chronic Granulomatous Disease.
Granulomatous Disease, Chronic
Intracellular generation of superoxide by the phagocyte NADPH oxidase: How, where, and what for?
Granulomatous Disease, Chronic
Intracellular Neutrophil Oxidants: From Laboratory Curiosity to Clinical Reality.
Granulomatous Disease, Chronic
Intractable colitis associated with chronic granulomatous disease in a young girl.
Granulomatous Disease, Chronic
Intrapulmonary Mycobacterium avium infection as the first manifestation of chronic granulomatous disease.
Granulomatous Disease, Chronic
Investigation into the relationship between calyculin A-mediated potentiation of NADPH oxidase activity and inhibition of store-operated uptake of calcium by human neutrophils.
Granulomatous Disease, Chronic
Involvement of a functional NADPH oxidase in neutrophils and macrophages during programmed cell clearance: implications for chronic granulomatous disease.
Granulomatous Disease, Chronic
Involvement of p40phox in activation of phagocyte NADPH oxidase through association of its carboxyl-terminal, but not its amino-terminal, with p67phox.
Granulomatous Disease, Chronic
IRE1? mediates PKR activation in response to Chlamydia trachomatis infection.
Granulomatous Disease, Chronic
Killing of Mycobacterium tuberculosis by neutrophils: a nonoxidative process.
Granulomatous Disease, Chronic
Lentivirus-mediated gene transfer of gp91phox corrects chronic granulomatous disease (CGD) phenotype in human X-CGD cells.
Granulomatous Disease, Chronic
Lessons about the pathogenesis and management of aspergillosis from studies in chronic granulomatous disease.
Granulomatous Disease, Chronic
Leukotriene B4 metabolism in neutrophils of patients with chronic granulomatous disease: phorbol myristate acetate decreases endogenous leukotriene B4 via NADPH oxidase-dependent mechanism.
Granulomatous Disease, Chronic
Long polymerase chain reaction-based fluorescence in situ hybridization analysis of female carriers of X-linked chronic granulomatous disease deletions.
Granulomatous Disease, Chronic
Long-term high-level reconstitution of NADPH oxidase activity in murine X-linked chronic granulomatous disease using a bicistronic vector expressing gp91phox and a Delta LNGFR cell surface marker.
Granulomatous Disease, Chronic
Missense mutations in the gp91-phox gene encoding cytochrome b558 in patients with cytochrome b positive and negative X-linked chronic granulomatous disease.
Granulomatous Disease, Chronic
Molecular analysis of X-linked chronic granulomatous disease in five unrelated Korean patients.
Granulomatous Disease, Chronic
Molecular Basis of Autosomal Recessive Chronic Granulomatous Disease in Iran.
Granulomatous Disease, Chronic
Molecular characterization of a large cohort of patients with Chronic Granulomatous Disease and identification of novel CYBB mutations: An Italian multicenter study.
Granulomatous Disease, Chronic
Molecular diagnosis of X-linked chronic granulomatous disease in Iran.
Granulomatous Disease, Chronic
Molecular dynamics study on the ligand recognition by tandem SH3 domains of p47phox, regulating NADPH oxidase activity.
Granulomatous Disease, Chronic
Molecular quality control machinery contributes to the leukocyte NADPH oxidase deficiency in chronic granulomatous disease.
Granulomatous Disease, Chronic
Monocyte- and Macrophage-Targeted NADPH Oxidase Mediates Antifungal Host Defense and Regulation of Acute Inflammation in Mice.
Granulomatous Disease, Chronic
Mutation at histidine 338 of gp91(phox) depletes FAD and affects expression of cytochrome b558 of the human NADPH oxidase.
Granulomatous Disease, Chronic
NADPH Oxidase 1 and Its Derived Reactive Oxygen Species Mediated Tissue Injury and Repair.
Granulomatous Disease, Chronic
NADPH oxidase activation regulates apoptotic neutrophil clearance by murine macrophages.
Granulomatous Disease, Chronic
NADPH oxidase activity and cytochrome b558 content of human Epstein-Barr-virus-transformed B lymphocytes correlate with expression of genes encoding components of the oxidase system.
Granulomatous Disease, Chronic
NADPH oxidase controls pulmonary neutrophil infiltration in the response to fungal cell walls by limiting LTB4.
Granulomatous Disease, Chronic
NADPH oxidase correction by mRNA transfection of apheresis granulocytes in chronic granulomatous disease.
Granulomatous Disease, Chronic
NADPH oxidase deficiency in X-linked chronic granulomatous disease.
Granulomatous Disease, Chronic
NADPH oxidase deficient mice develop colitis and bacteremia upon infection with normally avirulent, TTSS-1- and TTSS-2-deficient Salmonella Typhimurium.
Granulomatous Disease, Chronic
NADPH oxidase involvement in the pathology of Helicobacter pylori infection.
Granulomatous Disease, Chronic
NADPH oxidase is not essential for low density lipoprotein oxidation by human monocyte-derived macrophages.
Granulomatous Disease, Chronic
NADPH oxidase is not required for spontaneous and Staphylococcus aureus-induced apoptosis of monocytes.
Granulomatous Disease, Chronic
NADPH Oxidase Limits Collaborative Pattern-Recognition Receptor Signaling to Regulate Neutrophil Cytokine Production in Response to Fungal Pathogen-Associated Molecular Patterns.
Granulomatous Disease, Chronic
NADPH oxidase limits innate immune responses in the lungs in mice.
Granulomatous Disease, Chronic
NADPH oxidase promotes neutrophil extracellular trap formation in pulmonary aspergillosis.
Granulomatous Disease, Chronic
Neutrophil extracellular trap cell death requires both autophagy and superoxide generation.
Granulomatous Disease, Chronic
Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease.
Granulomatous Disease, Chronic
Neutrophil-derived TNF drives fungal acute lung injury in chronic granulomatous disease.
Granulomatous Disease, Chronic
Neutrophil-mediated oxidative burst and host defense are controlled by a Vav-PLCgamma2 signaling axis in mice.
Granulomatous Disease, Chronic
Nicotinamide-adenine dinucleotide phosphate oxidase assembly and activation in EBV-transformed B lymphoblastoid cell lines of normal and chronic granulomatous disease patients.
Granulomatous Disease, Chronic
Nitric oxide and peroxynitrite trigger and enhance release of neutrophil extracellular traps.
Granulomatous Disease, Chronic
Novel cell death program leads to neutrophil extracellular traps.
Granulomatous Disease, Chronic
NOX2 Deficiency Permits Sustained Survival of S. aureus in Macrophages and Contributes to Severity of Infection.
Granulomatous Disease, Chronic
Ocular manifestations in chronic granulomatous disease in Saudi Arabia.
Granulomatous Disease, Chronic
Osteomyelitis due to Aspergillus spp. in patients with chronic granulomatous disease: comparison of Aspergillus nidulans and Aspergillus fumigatus.
Granulomatous Disease, Chronic
Oxidant-mediated phosphatidylserine exposure and macrophage uptake of activated neutrophils: possible impairment in chronic granulomatous disease.
Granulomatous Disease, Chronic
P47(phox)-deficient NADPH oxidase defect in neutrophils of diabetic mouse strains, C57BL/6J-m db/db and db/+.
Granulomatous Disease, Chronic
p47phox-deficient immune microenvironment signals dysregulate naive T-cell apoptosis.
Granulomatous Disease, Chronic
Persistence of the Bacterial Pathogen Granulibacter bethesdensis in Chronic Granulomatous Disease Monocytes and Macrophages Lacking a Functional NADPH Oxidase.
Granulomatous Disease, Chronic
Phagocytic NADPH oxidase and its role in chronic granulomatous disease.
Granulomatous Disease, Chronic
Phorbol myristate acetate induced oxidation of 2',7'-dichlorofluorescin by neutrophils from patients with chronic granulomatous disease.
Granulomatous Disease, Chronic
PI(3)P-p40phox binding regulates NADPH oxidase activation in mouse macrophages and magnitude of inflammatory responses in vivo.
Granulomatous Disease, Chronic
Pivotal Advance: Eosinophilia in the MES rat strain is caused by a loss-of-function mutation in the gene for cytochrome b(-245), alpha polypeptide (Cyba).
Granulomatous Disease, Chronic
Point mutation in the cytoplasmic domain of the neutrophil p22-phox cytochrome b subunit is associated with a nonfunctional NADPH oxidase and chronic granulomatous disease.
Granulomatous Disease, Chronic
PPAR{gamma} activation normalizes resolution of acute sterile inflammation in murine chronic granulomatous disease.
Granulomatous Disease, Chronic
Preservation of complement-induced lung injury in mice with deficiency of NADPH oxidase.
Granulomatous Disease, Chronic
Protein delivery by Pseudomonas type III secretion system: Ex vivo complementation of p67(phox)-deficient chronic granulomatous disease.
Granulomatous Disease, Chronic
Pulmonary computed tomography scan findings in chronic granulomatous disease.
Granulomatous Disease, Chronic
Pyocyanin-enhanced neutrophil extracellular trap formation requires the NADPH oxidase.
Granulomatous Disease, Chronic
Rapid Detection of Intracellular p47phox and p67phox by Flow Cytometry; Useful Screening Tests for Chronic Granulomatous Disease.
Granulomatous Disease, Chronic
Rapid determination of chimerism status using dihydrorhodamine assay in a patient with X-linked chronic granulomatous disease following hematopoietic stem cell transplantation.
Granulomatous Disease, Chronic
Rapid whole-blood flow cytometry assay for diagnosis of chronic granulomatous disease.
Granulomatous Disease, Chronic
Rare Duplication or Deletion of Exons 6, 7 and 8 in CYBB Leading to X-Linked Chronic Granulomatous Disease in Two Patients from Different Families.
Granulomatous Disease, Chronic
Rasamsonia sp: An emerging infection amongst chronic granulomatous disease patients. A case of disseminated infection by a putatively novel Rasamsonia argillacea species complex involving the heart.
Granulomatous Disease, Chronic
Recombinant 47-kilodalton cytosol factor restores NADPH oxidase in chronic granulomatous disease.
Granulomatous Disease, Chronic
Recombinant interferon gamma augments phagocyte superoxide production and X-chronic granulomatous disease gene expression in X-linked variant chronic granulomatous disease.
Granulomatous Disease, Chronic
Reconstitution of NADPH oxidase activity in human X-linked chronic granulomatous disease myeloid cells after stable gene transfer using a recombinant adeno-associated virus 2 vector.
Granulomatous Disease, Chronic
Regulation of NADPH oxidase activity in phagocytes: relationship between FAD/NADPH binding and oxidase complex assembly.
Granulomatous Disease, Chronic
Renal transplantation in a patient with chronic granulomatous disease: case report.
Granulomatous Disease, Chronic
Residual NADPH oxidase activity and isolated lung involvement in x-linked chronic granulomatous disease.
Granulomatous Disease, Chronic
Residual NADPH oxidase and survival in chronic granulomatous disease.
Granulomatous Disease, Chronic
Respiratory complications after haematopoietic stem cell transplantation in a patient with chronic granulomatous disease.
Granulomatous Disease, Chronic
Restoration of superoxide generation to a chronic granulomatous disease-derived B-cell line by retrovirus mediated gene transfer.
Granulomatous Disease, Chronic
Retroviral-mediated gene transfer and nonmyeloablative conditioning: studies in a murine X-linked chronic granulomatous disease model.
Granulomatous Disease, Chronic
Role of Flow Cytometry in the Diagnosis of Chronic Granulomatous Disease: the Egyptian Experience.
Granulomatous Disease, Chronic
Role of NADPH oxidase in host defense against aspergillosis.
Granulomatous Disease, Chronic
Role of NADPH oxidase versus neutrophil proteases in antimicrobial host defense.
Granulomatous Disease, Chronic
Role of p47phox in antigen-presenting cell-mediated regulation of humoral immunity in mice.
Granulomatous Disease, Chronic
Safety and effectiveness of long-term interferon gamma therapy in patients with chronic granulomatous disease.
Granulomatous Disease, Chronic
Safety and Efficacy of Ustekinumab in the Inflammatory Bowel Disease of Chronic Granulomatous Disease.
Granulomatous Disease, Chronic
Severe glucose-6-phosphate dehydrogenase deficiency leads to susceptibility to infection and absent NETosis.
Granulomatous Disease, Chronic
Skewed X-inactivation in a Female Carrier with X-linked Chronic Granulomatous Disease.
Granulomatous Disease, Chronic
Study of naïve and memory cells in a cohort of Egyptian chronic granulomatous disease patients.
Granulomatous Disease, Chronic
Successful immune reconstitution by means of hematopoietic stem cell transplantation in a Colombian patient with chronic granulomatous disease.
Granulomatous Disease, Chronic
Successful renal transplantation in patients with chronic granulomatous disease.
Granulomatous Disease, Chronic
Sulfite stimulates NADPH oxidase of human neutrophils to produce active oxygen radicals via protein kinase C and Ca2+/calmodulin pathways.
Granulomatous Disease, Chronic
Synaptic plasticity deficits and mild memory impairments in mouse models of chronic granulomatous disease.
Granulomatous Disease, Chronic
Targeted gene addition in human CD34(+) hematopoietic cells for correction of X-linked chronic granulomatous disease.
Granulomatous Disease, Chronic
Targeted Repair of p47-CGD in iPSCs by CRISPR/Cas9: Functional Correction without Cleavage in the Highly Homologous Pseudogenes.
Granulomatous Disease, Chronic
Thapsigargin and flavin adenine dinucleotide ex vivo treatment rescues trafficking-defective gp91phox in chronic granulomatous disease leukocytes.
Granulomatous Disease, Chronic
The active N-terminal region of p67phox. Structure at 1.8 A resolution and biochemical characterizations of the A128V mutant implicated in chronic granulomatous disease.
Granulomatous Disease, Chronic
The glycoprotein encoded by the X-linked chronic granulomatous disease locus is a component of the neutrophil cytochrome b complex.
Granulomatous Disease, Chronic
The NADPH oxidase: lessons from chronic granulomatous disease neutrophils.
Granulomatous Disease, Chronic
The neutrophil-activating protein (HP-NAP) of Helicobacter pylori is a protective antigen and a major virulence factor.
Granulomatous Disease, Chronic
The p47(phox-/-) mouse model of chronic granulomatous disease has normal granuloma formation and cytokine responses to Mycobacterium avium and Schistosoma mansoni eggs.
Granulomatous Disease, Chronic
The relationship between alloimmunization and posttransfusion granulocyte survival: experience in a chronic granulomatous disease cohort.
Granulomatous Disease, Chronic
The role of reactive oxygen species (ROS) in the effector mechanisms of human antimycobacterial immunity.
Granulomatous Disease, Chronic
The search for a genetic defect in Polish patients with chronic granulomatous disease.
Granulomatous Disease, Chronic
The three CYBA variants (rs4673, rs1049254 and rs1049255) are benign: new evidence from a patient with CGD.
Granulomatous Disease, Chronic
Thymosin ?4 promotes autophagy and repair via HIF-1? stabilization in chronic granulomatous disease.
Granulomatous Disease, Chronic
Transducible form of p47phox and p67phox compensate for defective NADPH oxidase activity in neutrophils of patients with chronic granulomatous disease.
Granulomatous Disease, Chronic
Tumor necrosis factor and immune interferon synergistically induce cytochrome b-245 heavy-chain gene expression and nicotinamide-adenine dinucleotide phosphate hydrogenase oxidase in human leukemic myeloid cells.
Granulomatous Disease, Chronic
Two CGD Families with a Hypomorphic Mutation in the Activation Domain of p67(phox).
Granulomatous Disease, Chronic
Two x-linked chronic granulomatous disease patients with unusual NADPH oxidase properties.
Granulomatous Disease, Chronic
Undiagnosed Chronic Granulomatous Disease, Burkholderia cepacia complex Pneumonia, and Acquired Hemophagocytic Lymphohistiocytosis: A Deadly Association.
Granulomatous Disease, Chronic
Variant of X-Linked Chronic Granulomatous Disease Revealed by a Severe Burkholderia cepacia Invasive Infection in an Infant.
Granulomatous Disease, Chronic
Variations in the Phagosomal Environment of Human Neutrophils and Mononuclear Phagocyte Subsets.
Granulomatous Disease, Chronic
Virulence of catalase-deficient aspergillus nidulans in p47(phox)-/- mice. Implications for fungal pathogenicity and host defense in chronic granulomatous disease.
Granulomatous Disease, Chronic
X-linked chronic granulomatous disease secondary to skewed X chromosome inactivation in a female with a novel CYBB mutation and late presentation.
Granulomatous Disease, Chronic
X-linked chronic granulomatous disease: correction of NADPH oxidase defect by retrovirus-mediated expression of gp91-phox.
Granulomatous Disease, Chronic
X-linked chronic granulomatous disease: first report of mutations in patients of Argentina.
Granulomatous Disease, Chronic
X-Linked Chronic Granulomatous Disease: First Report of Mutations in Patients of Argentina.
Granulomatous Disease, Chronic
Xanthine oxidase contributes to host defense against Burkholderia cepacia in the p47(phox-/-) mouse model of chronic granulomatous disease.
Granulomatous Disease, Chronic
[A report of a family with chronic granulomatous disease with a gp91phox disorder]
Granulomatous Disease, Chronic
[Activation mechanism of neutrophil NADPH oxidase complex--molecular pathology of chronic granulomatous disease]
Granulomatous Disease, Chronic
[Chronic granulomatous disease (CGD): dysfunction of the neutrophil granulocyte NADPH-oxidase enzyme system]
Granulomatous Disease, Chronic
[Chronic granulomatous disease recognised in 42-years-old patient.]
Granulomatous Disease, Chronic
[Chronic granulomatous disease: pathogenesis and therapy of associated fungal infections].
Granulomatous Disease, Chronic
[Clinical, genetic and molecular characterization of the X-linked chronic granulomatous disease: A case report of a new splicing mutation].
Granulomatous Disease, Chronic
[Multifocal osteomyelitis as the first manifestation of chronic granulomatous disease]
Granulomatous Disease, Chronic
[Mycobacterial disease in patients with chronic granulomatous disease].
Granulomatous Disease, Chronic
[Prenatal diagnosis and novel mutation in X-linked chronic granulomatous disease.]
Granulomatous Disease, Chronic
[The X+ chronic granulomatous disease as a fabulous model to study the NADPH oxidase complex activation]
gtp cyclohydrolase i deficiency
High-cholesterol Diet Augments Endothelial Dysfunction via Elevated Oxidative Stress and Reduced BH(4) in Ins2(Akita) Mice, an Autosomal Dominant Mutant Type 1 Diabetic Model.
Hearing Loss
NOX3 NADPH Oxidase Couples Transient Receptor Potential Vanilloid 1 to STAT1-Mediated Inflammation and Hearing Loss.
Hearing Loss
Transtympanic Administration of Short Interfering (si)RNA for the NOX3 Isoform of NADPH Oxidase Protects Against Cisplatin-Induced Hearing Loss in the Rat.
Hearing Loss, Noise-Induced
Noise-induced changes in expression levels of NADPH oxidases in the cochlea.
Heart Diseases
Association of phagocytic NADPH oxidase activity with hypertensive heart disease: a role for cardiotrophin-1?
Heart Diseases
Recent Insights into the Biological Functions of Sestrins in Health and Disease.
Heart Failure
Activated glycine receptors may decrease endosomal NADPH oxidase activity by opposing ClC-3-mediated efflux of chloride from endosomes.
Heart Failure
Activation of NADPH oxidase during progression of cardiac hypertrophy to failure.
Heart Failure
Argirein alleviates vascular endothelial insulin resistance through suppressing the activation of Nox4-dependent O2- production in diabetic rats.
Heart Failure
Cardiomyocyte-specific overexpression of an active form of Rac predisposes the heart to increased myocardial stunning and ischemia-reperfusion injury.
Heart Failure
CPU228, a derivative of dofetilide, relieves cardiac dysfunction by normalizing FKBP12.6, NADPH oxidase and protein kinase C epsilon in the myocardium.
Heart Failure
Diaphragm Abnormalities in Patients with End-Stage Heart Failure: NADPH Oxidase Upregulation and Protein Oxidation.
Heart Failure
Enhanced ROS production by NADPH oxidase is correlated to changes in antioxidant enzyme activity in human heart failure.
Heart Failure
Enhanced susceptibility to biomechanical stress in ACE2 null mice is prevented by loss of the p47phox NADPH oxidase subunit.
Heart Failure
Enhanced TNF alpha and oxidative stress in patients with heart failure: effect of TNF alpha on platelet O2- production.
Heart Failure
Exercise training decreases NADPH oxidase activity and restores skeletal muscle mass in heart failure rats.
Heart Failure
Glucose-6-phosphate dehydrogenase: a novel therapeutic target in cardiovascular diseases.
Heart Failure
Influence of N- acetylcysteine on oxidative stress in slow-twitch soleus muscle of heart failure rats.
Heart Failure
Inhibition of NADPH oxidase reduces myocardial oxidative stress and apoptosis and improves cardiac function in heart failure after myocardial infarction.
Heart Failure
Inhibition of NADPH oxidase up-regulates connexin 43 and ameliorates electrical remodeling in rabbits with heart failure.
Heart Failure
NADPH oxidase inhibition ameliorates cardiac dysfunction in rabbits with heart failure.
Heart Failure
NADPH oxidase is involved in angiotensin II-induced apoptosis in H9C2 cardiac muscle cells: Effects of apocynin.
Heart Failure
NADPH oxidase-dependent redox signaling in human heart failure: relationship between the left and right ventricle.
Heart Failure
NADPH oxidase-dependent redox signalling in cardiac hypertrophy, remodelling and failure.
Heart Failure
NADPH oxidase/ROS-dependent PYK2 activation is involved in TNF-?-induced matrix metalloproteinase-9 expression in rat heart-derived H9c2 cells.
Heart Failure
Neutrophil-Initiated Myocardial Inflammation and Its Modulation by B-Type Natriuretic Peptide: A Potential Therapeutic Target.
Heart Failure
Parsing the role of NADPH oxidase enzymes and reactive oxygen species in heart failure.
Heart Failure
Rac1-Mediated Activation of Mineralocorticoid Receptor in Pressure Overload-Induced Cardiac Injury.
Heart Failure
Regulation of NADPH oxidase subunit p22(phox) by NF-kB in human aortic smooth muscle cells.
Heart Failure
Right-ventricular failure is associated with increased mitochondrial complex II activity and production of reactive oxygen species.
Heart Failure
S-Glutathionylation Reshapes Our Understanding of Endothelial Nitric Oxide Synthase Uncoupling and Nitric Oxide/Reactive Oxygen Species-Mediated Signaling.
Heart Failure
The NADPH oxidase inhibitor apocynin improves cardiac sympathetic nerve terminal innervation and function in heart failure.
Heart Failure
[Correlation between left ventricular mass index and NADPH oxidase p22phox in patients with non-valvular chronic heart failure].
Heart Failure
[Effects of NADPH oxidase inhibition on cardiac function and myocardial calcium regulatory proteins in rabbits with heart failure]
Hematologic Diseases
Generation of X-CGD cells for vector evaluation from healthy donor CD34(+) HSCs by shRNA-mediated knock down of gp91(phox).
Hemochromatosis
Potential thrombophilic mutations/polymorphisms in patients with no flow-limiting stenosis after myocardial infarction.
Hepatic Encephalopathy
Elevated dopamine induces minimal hepatic encephalopathy by activation of astrocytic NADPH oxidase and astrocytic protein tyrosine nitration.
Hepatitis
Histamine dihydrochloride protects against early alcohol-induced liver injury in a rat model.
Hepatitis
NADPH oxidase-derived free radicals are key oxidants in alcohol-induced liver disease.
Hepatitis C
Nonstructural 3 protein of hepatitis C virus triggers an oxidative burst in human monocytes via activation of NADPH oxidase.
Hepatitis C, Chronic
Effects of Losartan on Hepatic Expression of Non-phagocytic NADPH Oxidase and Fibrogenic Genes in Patients with Chronic Hepatitis C.
Hepatitis, Alcoholic
Defective monocyte oxidative burst predicts infection in alcoholic hepatitis and is associated with reduced expression of NADPH oxidase.
Hepatoblastoma
Atrial natriuretic peptide induces cell death in human hepatoblastoma (HepG2) through the involvement of NADPH oxidase.
HIV Infections
NADPH oxidase drives cytokine and neurotoxin release from microglia and macrophages in response to HIV-Tat.
HIV Infections
[Analysis of p22-phox and p47-phox subcellular localization and distribution in neutrophils from human immunodeficiency virus (HIV) infected patients].
Hodgkin Disease
Hodgkin-Reed-Sternberg cells in classical Hodgkin lymphoma show alterations of genes encoding the NADPH oxidase complex and impaired reactive oxygen species synthesis capacity.
Homocystinuria
Cystathionine beta synthase deficiency induces catalase-mediated hydrogen peroxide detoxification in mice liver.
Huntington Disease
Acute exposure to chlorpyrifos caused NADPH oxidase mediated oxidative stress and neurotoxicity in a striatal cell model of Huntington's disease.
Huntington Disease
Elevated NADPH oxidase activity contributes to oxidative stress and cell death in Huntington's disease.
Huntington Disease
Retracted: Elevated NADPH oxidase activity contributes to oxidative stress and cell death in Huntington's disease.
Hyperaldosteronism
Aldosterone increases kidney tubule cell oxidants through calcium-mediated activation of NADPH oxidase and nitric oxide synthase.
Hyperalgesia
Argan Oil as an Effective Nutri-Therapeutic Agent in Metabolic Syndrome: A Preclinical Study.
Hyperalgesia
Oral phycocyanobilin may diminish the pathogenicity of activated brain microglia in neurodegenerative disorders.
Hyperalgesia
Reactive oxygen species derived from NOX1/NADPH oxidase enhance inflammatory pain.
Hyperalgesia
Role for peroxynitrite in sphingosine-1-phosphate-induced hyperalgesia in rats.
Hyperalgesia
Rostral ventromedial medulla-mediated descending facilitation following P2X7 receptor activation is involved in the development of chronic post-operative pain.
Hyperalgesia
Spinal NADPH oxidase is a source of superoxide in the development of morphine-induced hyperalgesia and antinociceptive tolerance.
Hyperalgesia
Superoxide anion-induced pain and inflammation depends on TNF?/TNFR1 signaling in mice.
Hyperargininemia
High concentration of L-arginine suppresses nitric oxide synthase activity and produces reactive oxygen species in NB9 human neuroblastoma cells.
Hypercholesterolemia
Augmented superoxide production by Nox2-containing NADPH oxidase causes cerebral artery dysfunction during hypercholesterolemia.
Hypercholesterolemia
CD40 ligand enhances monocyte tissue factor expression and thrombin generation via oxidative stress in patients with hypercholesterolemia.
Hypercholesterolemia
Cerebral microvascular responses to hypercholesterolemia: roles of NADPH oxidase and P-selectin.
Hypercholesterolemia
Impaired superoxide production due to a deficiency in phagocyte NADPH oxidase fails to inhibit atherosclerosis in mice.
Hypercholesterolemia
LDL are oxidatively modified by platelets via GP91(phox) and accumulate in human monocytes.
Hypercholesterolemia
Persistence of the nitric oxide pathway in the aorta of hypercholesterolemic apolipoprotein-E-deficient mice.
Hyperemia
Angiotensin II impairs neurovascular coupling in neocortex through NADPH oxidase-derived radicals.
Hyperglycemia
?3 Adrenergic Stimulation Restores Nitric Oxide/Redox Balance and Enhances Endothelial Function in Hyperglycemia.
Hyperglycemia
?3-Adrenoceptor activation relieves oxidative inhibition of the cardiac Na+-K+ pump in hyperglycemia induced by insulin receptor blockade.
Hyperglycemia
Abundance of TRPC6 protein in glomerular mesangial cells is decreased by ROS and PKC in diabetes.
Hyperglycemia
Acetylcholine-induced relaxation of rabbit basilar artery in vitro is rapidly reduced by reactive oxygen species in acute hyperglycemia: role of NADPH oxidase.
Hyperglycemia
AMPK activation by glucagon-like peptide-1 prevents NADPH oxidase activation induced by hyperglycemia in adult cardiomyocytes.
Hyperglycemia
Angiotensin-(1-7) prevents diabetes-induced attenuation in PPAR-gamma and catalase activities.
Hyperglycemia
Cardioprotective effects of polydatin against myocardial injury in diabetic rats via inhibition of NADPH oxidase and NF-?B activities.
Hyperglycemia
Chronic hyperglycemia predisposes to exaggerated inflammatory response and leukocyte dysfunction in Akita mice.
Hyperglycemia
Curcumin ameliorated diabetic neuropathy partially by inhibition of NADPH oxidase mediating oxidative stress in the spinal cord.
Hyperglycemia
Diabetes Upregulates Oxidative Stress and Downregulates Cardiac Protection to Exacerbate Myocardial Ischemia/Reperfusion Injury in Rats.
Hyperglycemia
Endothelium-dependent vasodilation in the cerebral arterioles of rats deteriorates during acute hyperglycemia and then is restored by reducing the glucose level.
Hyperglycemia
Gene therapy of endothelial nitric oxide synthase and manganese superoxide dismutase restores delayed wound healing in type 1 diabetic mice.
Hyperglycemia
High glucose-induced oxidative stress inhibits Na+/glucose cotransporter activity in renal proximal tubule cells.
Hyperglycemia
Hyperglycemia-Mediated Oxidative Stress Increases Pulmonary Vascular Permeability.
Hyperglycemia
Lack of p47(phox) in Akita Diabetic Mice Is Associated with Interstitial Pneumonia, Fibrosis, and Oral Inflammation.
Hyperglycemia
Modified kinetics of generation of reactive species in peripheral blood of patients with type 2 diabetes.
Hyperglycemia
NADPH oxidase activation by hyperglycemia in cardiomyocytes is independent of glucose metabolism but requires SGLT1.
Hyperglycemia
NADPH Oxidase Activity in Cerebral Arterioles Is a Key Mediator of Cerebral Small Vessel Disease-Implications for Prevention.
Hyperglycemia
Neonatal hyperglycemia induces oxidative stress in the rat brain: the role of pentose phosphate pathway enzymes and NADPH oxidase.
Hyperglycemia
Perivascular Cells and NADPH Oxidase Inhibition Partially Restore Hyperglycemia-Induced Alterations in Hematopoietic Stem Cell and Myeloid-Derived Suppressor Cell Populations in the Bone Marrow.
Hyperglycemia
Peroxynitrite activates NLRP3 inflammasome and contributes to hemorrhagic transformation and poor outcome in ischemic stroke with hyperglycemia.
Hyperglycemia
Priming of neutrophil oxidative burst in diabetes requires preassembly of the NADPH oxidase.
Hyperglycemia
Prorenin receptor (PRR)-mediated NADPH oxidase (Nox) signaling regulates VEGF synthesis under hyperglycemic condition in ARPE-19 cells.
Hyperglycemia
Regulation of NADPH oxidase activity is associated with miRNA-25-mediated NOX4 expression in experimental diabetic nephropathy.
Hyperglycemia
Short-term intravenous insulin infusion is associated with reduced expression of NADPH oxidase p47(phox) subunit in monocytes from type 2 diabetes patients.
Hyperglycemia
Spironolactone improves nephropathy by enhancing glucose-6-phosphate dehydrogenase activity and reducing oxidative stress in diabetic hypertensive rat.
Hyperglycemia
Studying neuroprotective effect of Atorvastatin as a small molecule drug on high glucose-induced neurotoxicity in undifferentiated PC12 cells: role of NADPH oxidase.
Hyperhomocysteinemia
Acid sphingomyelinase gene deficiency ameliorates the hyperhomocysteinemia-induced glomerular injury in mice.
Hyperhomocysteinemia
Epithelial-to-mesenchymal transition in podocytes mediated by activation of NADPH oxidase in hyperhomocysteinemia.
Hyperhomocysteinemia
Folic acid supplementation inhibits NADPH oxidase-mediated superoxide anion production in the kidney.
Hyperhomocysteinemia
Homocysteine stimulates NADPH oxidase-mediated superoxide production leading to endothelial dysfunction in rats.
Hyperhomocysteinemia
Hyperhomocysteinemia, a cardiac metabolic disease: role of nitric oxide and the p22phox subunit of NADPH oxidase.
Hyperhomocysteinemia
Picroside II attenuates hyperhomocysteinemia-induced endothelial injury by reducing inflammation, oxidative stress and cell apoptosis.
Hyperinsulinism
Hyperinsulinemia-induced vascular smooth muscle cell (VSMC) migration and proliferation is mediated by converging mechanisms of mitochondrial dysfunction and oxidative stress.
Hyperinsulinism
Nox2 contributes to hyperinsulinemia-induced redox imbalance and impaired vascular function.
Hyperinsulinism
Phagocytic NADPH oxidase overactivity underlies oxidative stress in metabolic syndrome.
Hyperlipidemias
Endothelial cell superoxide generation: regulation and relevance for cardiovascular pathophysiology.
Hyperlipidemias
Increased oxidative stress in obesity and its impact on metabolic syndrome.
Hyperlipidemias
Involvement of NADPH oxidases and non-muscle myosin light chain in senescence of endothelial progenitor cells in hyperlipidemia.
Hyperlipidemias
Nebivolol prevents vascular NOS III uncoupling in experimental hyperlipidemia and inhibits NADPH oxidase activity in inflammatory cells.
Hyperlipidemias
Superoxide dismutase mimetic M40403 improves endothelial function in apolipoprotein(E)-deficient mice.
Hyperlipidemias
[Genetic risk factors for ischemic cerebrovascular disease--analysis on fifteen candidate prothrombotic gene polymorphisms in the Japanese population]
Hyperoxaluria
Apocynin-treatment reverses hyperoxaluria induced changes in NADPH oxidase system expression in rat kidneys: a transcriptional study.
Hyperoxaluria
Ayurvedic medicine and NADPH oxidase: a possible approach to the prevention of ESRD in hyperoxaluria.
Hyperoxaluria
Design and characterization of apocynin loaded PLGA nanoparticles and their in vivo efficacy in hyperoxaluric rats.
Hyperoxaluria
Effect of NADPH oxidase inhibition on the expression of kidney injury molecule and calcium oxalate crystal deposition in hydroxy-L-proline-induced hyperoxaluria in the male Sprague-Dawley rats.
Hyperoxaluria
Opportunities for future therapeutic interventions for hyperoxaluria: targeting oxidative stress.
Hyperoxaluria
Role of mitochondria and NADPH oxidase derived reactive oxygen species in hyperoxaluria induced nephrolithiasis: therapeutic intervention with combinatorial therapy of N-acetyl cysteine and Apocynin.
Hypersensitivity
Advanced Oxidative Protein Products Cause Pain Hypersensitivity in Rats by Inducing Dorsal Root Ganglion Neurons Apoptosis via NADPH Oxidase 4/c-Jun N-terminal Kinase Pathways.
Hypersensitivity
Modulation of chronic hypoxia-induced chemoreceptor hypersensitivity by NADPH oxidase subunits in rat carotid body.
Hypersensitivity
NADPH Oxidase-Derived ROS Induced by Chronic Intermittent Hypoxia Mediates Hypersensitivity of Lung Vagal C Fibers in Rats.
Hypersensitivity
Nociceptive behavior induced by chemotherapeutic paclitaxel and beneficial role of antioxidative pathways.
Hypersensitivity
Oxidative stress and alpha(1)-adrenoceptor-mediated stimulation of the Cl(-)/HCO(3)(-) exchanger in immortalized SHR proximal tubular epithelial cells.
Hypersensitivity
ROS-mediated vascular homeostatic control of root-to-shoot soil Na delivery in Arabidopsis.
Hypersensitivity
Three novel mutations in CYBA among 22 Iranians with Chronic granulomatous disease.
Hypertension
"Angiotensin II memory" contributes to the development of hypertension and vascular injury via activation of NADPH oxidase.
Hypertension
A Drosophila model for the screening of bioavailable NADPH oxidase inhibitors and antioxidants.
Hypertension
A novel CYBA variant, the -675A/T polymorphism, is associated with essential hypertension.
Hypertension
A Synthetic Peptide from Transforming Growth Factor-?1 Type III Receptor Inhibits NADPH Oxidase and Prevents Oxidative Stress in the Kidney of Spontaneously Hypertensive Rats.
Hypertension
ACE2-Mediated Reduction of Oxidative Stress in the Central Nervous System Is Associated with Improvement of Autonomic Function.
Hypertension
Activation of vascular p38MAPK by mechanical stretch is independent of c-Src and NADPH oxidase: influence of hypertension and angiotensin II.
Hypertension
Aldosterone mediates angiotensin II-induced interstitial cardiac fibrosis via a Nox2-containing NADPH oxidase.
Hypertension
Alterations in the subcellular distribution of NADPH oxidase p47(phox) in hypothalamic paraventricular neurons following slow pressor Angiotensin II hypertension in female mice with accelerated ovarian failure.
Hypertension
Angiotensin Converting Enzyme 2 antagonizes Ang II-induced pressor response and NADPH oxidase activation in WKY rats and in SHR model.
Hypertension
Angiotensin II induces p67phox mRNA expression and NADPH oxidase superoxide generation in rabbit aortic adventitial fibroblasts.
Hypertension
Angiotensin II-dependent chronic hypertension and cardiac hypertrophy are unaffected by gp91phox-containing NADPH oxidase.
Hypertension
Angiotensin-(1-7) prevents diabetes-induced attenuation in PPAR-gamma and catalase activities.
Hypertension
Antioxidant effect of imperatorin from Angelica dahurica in hypertension via inhibiting NADPH oxidase activation and MAPK pathway.
Hypertension
Antioxidant effects of vitamins C and E are associated with altered activation of vascular NADPH oxidase and superoxide dismutase in stroke-prone SHR.
Hypertension
Aortic dysfunction by chronic cadmium exposure is linked to multiple metabolic risk factors that converge in anion superoxide production.
Hypertension
Apocynin activity in spontaneously hypertensive rats (SHR): preliminary studies in vivo.
Hypertension
Apocynin Ameliorates Cadmium-Induced Hypertension Through Elevation of Endothelium Nitric Oxide Synthase.
Hypertension
Apocynin attenuates oxidative stress and hypertension in young spontaneously hypertensive rats independent of ADMA/NO pathway.
Hypertension
Apocynin attenuates tubular apoptosis and tubulointerstitial fibrosis in transgenic mice independent of hypertension.
Hypertension
Aspirin suppresses cardiac fibroblast proliferation and collagen formation through downregulation of angiotensin type 1 receptor transcription.
Hypertension
Association between p22PHOX gene C242T polymorphism and hypertension in end-stage kidney disease patients.
Hypertension
Association of the -262C/T polymorphism in the catalase gene promoter and the C242T polymorphism of the NADPH oxidase P22phox gene with essential arterial hypertension in patients with diabetes mellitus type 2.
Hypertension
Associations of NADPH oxidase-related genes with blood pressure changes and incident hypertension: The GenSalt Study.
Hypertension
C242T polymorphism of the NADPH oxidase p22PHOX gene and its association with endothelial dysfunction in asymptomatic individuals with essential systemic hypertension.
Hypertension
Cadmium exposure activates NADPH oxidase, renin-angiotensin system and cyclooxygenase 2 pathways in arteries, inducing hypertension and vascular damage.
Hypertension
Central interactions of aldosterone and angiotensin II in aldosterone- and angiotensin II-induced hypertension.
Hypertension
Chronic alcohol-induced oxidative endothelial injury relates to angiotensin II levels in the rat.
Hypertension
Chronic cigarette smoke exposure triggers a vicious cycle of leukocyte and endothelial-mediated oxidant stress that results in vascular dysfunction.
Hypertension
D1-Like Receptors Regulate NADPH Oxidase Activity and Subunit Expression in Lipid Raft Microdomains of Renal Proximal Tubule Cells.
Hypertension
Differential regulation of NADPH oxidase in sympathetic and sensory Ganglia in deoxycorticosterone acetate salt hypertension.
Hypertension
Effect of apocynin treatment on renal expression of COX-2, NOS1, and renin in Wistar-Kyoto and spontaneously hypertensive rats.
Hypertension
Effect of hyperhomocystinemia and hypertension on endothelial function in methylenetetrahydrofolate reductase-deficient mice.
Hypertension
Effect of NADPH oxidase inhibitor apocynin on the expression of hypoxia-induced factor-1? and endothelin-1 in rat carotid body exposed to chronic intermittent hypoxia.
Hypertension
Effects of aortic coarctation on aortic antioxidant enzymes and NADPH oxidase protein expression.
Hypertension
Effects of continuous ingestion of hesperidin and glucosyl hesperidin on vascular gene expression in spontaneously hypertensive rats.
Hypertension
Elevated peripheral blood mononuclear cell-derived superoxide production in healthy young black men.
Hypertension
Elevated systemic TGF-beta impairs aortic vasomotor function through activation of NADPH oxidase-driven superoxide production and leads to hypertension, myocardial remodeling, and increased plaque formation in apoE(-/-) mice.
Hypertension
Ellagic Acid Prevents L-NAME-Induced Hypertension via Restoration of eNOS and p47phox Expression in Rats.
Hypertension
Endothelin-1-induced oxidative stress in DOCA-salt hypertension involves NADPH-oxidase-independent mechanisms.
Hypertension
Enhanced platelet release of superoxide anion in systemic hypertension: role of AT1 receptors.
Hypertension
EPA:DHA 6:1 prevents angiotensin II-induced hypertension and endothelial dysfunction in rats: role of NADPH oxidase- and COX-derived oxidative stress.
Hypertension
Epicatechin lowers blood pressure, restores endothelial function, and decreases oxidative stress and endothelin-1 and NADPH oxidase activity in DOCA-salt hypertension.
Hypertension
Erratum to: Role of endothelial Nox2 NADPH oxidase in angiotensin II-induced hypertension and vasomotor dysfunction.
Hypertension
Exaggerated vasomotor response to ANG II in rats with fetal programming of hypertension associated with exposure to a low-protein diet during gestation.
Hypertension
Exercise training, NADPH oxidase p22phox gene polymorphisms, and hypertension.
Hypertension
Extracts enriched in different polyphenolic families normalize increased cardiac NADPH oxidase expression while having differential effects on insulin resistance, hypertension, and cardiac hypertrophy in high-fructose-fed rats.
Hypertension
Functional and genetic characterization of two extremely rare cases of Williams-Beuren syndrome associated with chronic granulomatous disease.
Hypertension
Functional effect of the p22phox -930A/G polymorphism on p22phox expression and NADPH oxidase activity in hypertension.
Hypertension
G allele of the -930A>G polymorphism of the CYBA gene is associated with insulin resistance in obese subjects.
Hypertension
Garcinia mangostana pericarp extract protects against oxidative stress and cardiovascular remodeling via suppression of p47(phox) and iNOS in nitric oxide deficient rats.
Hypertension
Genetic polymorphisms of oxidative and antioxidant enzymes and arsenic-related hypertension.
Hypertension
Glucose-6 phosphate dehydrogenase deficiency decreases the vascular response to angiotensin II.
Hypertension
Hemin decreases cardiac oxidative stress and fibrosis in a rat model of systemic hypertension via PI3K/Akt signaling.
Hypertension
Hemizygosity at the NCF1 Gene in Patients with Williams-Beuren Syndrome Decreases Their Risk of Hypertension.
Hypertension
High Salt Intake Delayed Angiotensin II-Induced Hypertension in Mice With a Genetic Variant of NADPH Oxidase.
Hypertension
Immune activation caused by vascular oxidation promotes fibrosis and hypertension.
Hypertension
Increased free radical production in hypertension due to increased expression of the NADPH oxidase subunit p22(phox) in lymphoblast cell lines.
Hypertension
Increased NADPH oxidase activity mediates spontaneous aortic tone in genetically hypertensive rats.
Hypertension
Inhibition of the ROS-EGFR Pathway Mediates the Protective Action of Nox1/4 Inhibitor GKT137831 against Hypertensive Cardiac Hypertrophy via Suppressing Cardiac Inflammation and Activation of Akt and ERK1/2.
Hypertension
Interleukin-10 Released by CD4+CD25+ Natural Regulatory T Cells Improves Microvascular Endothelial Function Through Inhibition of NADPH Oxidase Activity in Hypertensive Mice.
Hypertension
Intermedin in Paraventricular Nucleus Attenuates Ang II-Induced Sympathoexcitation through the Inhibition of NADPH Oxidase-Dependent ROS Generation in Obese Rats with Hypertension.
Hypertension
L-arginine reverses p47phox and gp91phox expression induced by high salt in Dahl rats.
Hypertension
Lancemaside A from Codonopsis lanceolata prevents hypertension by inhibiting NADPH oxidase 2-mediated MAPK signalling and improving NO bioavailability in rats.
Hypertension
Low-dose dextromethorphan, a NADPH oxidase inhibitor, reduces blood pressure and enhances vascular protection in experimental hypertension.
Hypertension
Lysozyme M-Positive Monocytes Mediate Angiotensin II-Induced Arterial Hypertension and Vascular Dysfunction.
Hypertension
MAPK pathway activation by chronic lead-exposure increases vascular reactivity through oxidative stress/cyclooxygenase-2-dependent pathways.
Hypertension
Marinobufagenin and cyclic strain may activate endothelial NADPH oxidase, contributing to the adverse impact of salty diets on vascular and cerebral health.
Hypertension
Membrane rafts-redox signalling pathway contributes to renal fibrosis via modulation of the renal tubular epithelial-mesenchymal transition.
Hypertension
Membrane Trafficking of NADPH Oxidase p47phox in Paraventricular Hypothalamic Neurons Parallels Local Free Radical Production in Angiotensin II Slow-Pressor Hypertension.
Hypertension
Mitochondrial Thioredoxin: novel regulator for NADPH oxidase and angiotensin II-induced hypertension.
Hypertension
mPGES-1 (Microsomal Prostaglandin E Synthase-1) Mediates Vascular Dysfunction in Hypertension Through Oxidative Stress.
Hypertension
NADPH Oxidase Activity in Cerebral Arterioles Is a Key Mediator of Cerebral Small Vessel Disease-Implications for Prevention.
Hypertension
NADPH oxidase contributes to renal damage and dysfunction in Dahl salt-sensitive hypertension.
Hypertension
NADPH oxidase in the renal medulla causes oxidative stress and contributes to salt-sensitive hypertension in Dahl S rats.
Hypertension
NADPH oxidase in the renal microvasculature is a primary target for blood pressure-lowering effects by inorganic nitrate and nitrite.
Hypertension
NADPH oxidase in the vasculature: Expression, regulation and signalling pathways; role in normal cardiovascular physiology and its dysregulation in hypertension.
Hypertension
NADPH oxidase inhibition attenuates oxidative stress but not hypertension produced by chronic ET-1.
Hypertension
NADPH Oxidase Plays a Role on Ethanol-Induced Hypertension and Reactive Oxygen Species Generation in the Vasculature.
Hypertension
NADPH oxidase-derived superoxide augments endothelin-1-induced venoconstriction in mineralocorticoid hypertension.
Hypertension
NADPH oxidase-mediated oxidative stress: genetic studies of the p22(phox) gene in hypertension.
Hypertension
NADPH oxidase: its potential role in promotion of pulmonary arterial hypertension.
Hypertension
Nebivolol inhibits superoxide formation by NADPH oxidase and endothelial dysfunction in angiotensin II-treated rats.
Hypertension
Neurovascular coupling in the normal brain and in hypertension, stroke, and Alzheimer disease.
Hypertension
New roles for old pathways? A circuitous relationship between reactive oxygen species and cyclo-oxygenase in hypertension.
Hypertension
Nitric oxide generation by the organic nitrate NDBP attenuates oxidative stress and angiotensin II-mediated hypertension.
Hypertension
Nitric oxide, oxidative stress and vascular endothelium in health and hypertension.
Hypertension
Non-muscle myosin light chain promotes endothelial progenitor cells senescence and dysfunction in pulmonary hypertensive rats through up-regulation of NADPH oxidase.
Hypertension
Nox isoforms in vascular pathophysiology: insights from transgenic and knockout mouse models.
Hypertension
Nox1/4 inhibition exacerbates age dependent perivascular inflammation and fibrosis in a model of spontaneous hypertension.
Hypertension
Nox2 deficiency prevents hypertension-induced vascular dysfunction and hypertrophy in cerebral arterioles.
Hypertension
NOX2-derived reactive oxygen species in immune cells exacerbates salt-sensitive hypertension.
Hypertension
NOX5-induced uncoupling of endothelial NO synthase is a causal mechanism and theragnostic target of an age-related hypertension endotype.
Hypertension
Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension.
Hypertension
Oxidative stress contributes to sex differences in angiotensin II-mediated hypertension in spontaneously hypertensive rats.
Hypertension
Pathogenesis of target organ damage in hypertension: role of mitochondrial oxidative stress.
Hypertension
Polyphenols restore endothelial function in DOCA-salt hypertension: role of endothelin-1 and NADPH oxidase.
Hypertension
Protein disulfide isomerase expression increases in resistance arteries during hypertension development. Effects on Nox1 NADPH oxidase signaling.
Hypertension
PVN adenovirus-siRNA injections silencing either NOX2 or NOX4 attenuate aldosterone/NaCl-induced hypertension in mice.
Hypertension
Reactive oxygen species in the cerebral circulation: physiological roles and therapeutic implications for hypertension and stroke.
Hypertension
Red wine polyphenols prevent angiotensin II-induced hypertension and endothelial dysfunction in rats: role of NADPH oxidase.
Hypertension
Reduced NOS3 phosphorylation mediates reduced NO/cGMP signaling in mesenteric arteries of deoxycorticosterone acetate-salt hypertensive rats.
Hypertension
Regression of glomerular and tubulointerstitial injuries by dietary salt reduction with combination therapy of angiotensin II receptor blocker and calcium channel blocker in Dahl salt-sensitive rats.
Hypertension
Regulation of NADPH oxidase subunit p22(phox) by NF-kB in human aortic smooth muscle cells.
Hypertension
Relative contributions of mitochondria and NADPH oxidase to deoxycorticosterone acetate-salt hypertension in mice.
Hypertension
Renal ischemia-reperfusion leads to hypertension and changes in proximal tubule Na+ transport and renin-angiotensin-aldosterone system: Role of NADPH oxidase.
Hypertension
Renal molecular mechanisms underlying altered Na+ handling and genesis of hypertension during adulthood in prenatally undernourished rats.
Hypertension
Renal redox-sensitive signaling, but not blood pressure, is attenuated by Nox1 knockout in angiotensin II-dependent chronic hypertension.
Hypertension
Requirement for Rac1-dependent NADPH oxidase in the cardiovascular and dipsogenic actions of angiotensin II in the brain.
Hypertension
Resveratrol Inhibition of Rac1-Derived Reactive Oxygen Species by AMPK Decreases Blood Pressure in a Fructose-Induced Rat Model of Hypertension.
Hypertension
Resveratrol Regulates Blood Pressure by Enhancing AMPK Signaling to Downregulate a Rac1-Derived NADPH Oxidase in the Central Nervous System.
Hypertension
Right-ventricular failure is associated with increased mitochondrial complex II activity and production of reactive oxygen species.
Hypertension
RNA silencing in vivo reveals role of p22phox in rat angiotensin slow pressor response.
Hypertension
RNF34 ablation promotes cerebrovascular remodeling and hypertension by increasing NADPH-derived ROS generation.
Hypertension
Role of endothelial Nox2 NADPH oxidase in angiotensin II-induced hypertension and vasomotor dysfunction.
Hypertension
Role of extracellular superoxide dismutase in the mouse angiotensin slow pressor response.
Hypertension
Role of gp91phox-containing NADPH oxidase in the deoxycorticosterone acetate-salt-induced hypertension.
Hypertension
Role of reactive oxygen species in chronic hypoxia-induced pulmonary hypertension and vascular remodeling.
Hypertension
Role of the T cell in the genesis of angiotensin II induced hypertension and vascular dysfunction.
Hypertension
S-Glutathionylation Reshapes Our Understanding of Endothelial Nitric Oxide Synthase Uncoupling and Nitric Oxide/Reactive Oxygen Species-Mediated Signaling.
Hypertension
Selective recapitulation of conserved and nonconserved regions of putative NOXA1 protein activation domain confers isoform-specific inhibition of Nox1 oxidase and attenuation of endothelial cell migration.
Hypertension
Sex differences in angiotensin signaling in bulbospinal neurons in the rat rostral ventrolateral medulla.
Hypertension
Sex differences in maternal gestational hypertension-induced sensitization of angiotensin II hypertension in rat offspring: the protective effect of estrogen.
Hypertension
Sodium nitrite downregulates vascular NADPH oxidase and exerts antihypertensive effects in hypertension.
Hypertension
Superoxide anion is elevated in sympathetic neurons in DOCA-salt hypertension via activation of NADPH oxidase.
Hypertension
Superoxide dismutase, catalase, glutathione peroxidase and NADPH oxidase in lead-induced hypertension.
Hypertension
Sympathoexcitation by oxidative stress in the brain mediates arterial pressure elevation in obesity-induced hypertension.
Hypertension
The C242T CYBA polymorphism of NADPH oxidase is associated with essential hypertension.
Hypertension
The effects of novokinin, an AT2 agonist, on blood pressure, vascular responses, and levels of ADMA, NADPH oxidase, and Rho kinase in hypertension induced by NOS inhibition and salt.
Hypertension
The elevated blood pressure of human GRK4gamma A142V transgenic mice is not associated with increased ROS production.
Hypertension
The natural phenolic compounds as modulators of NADPH oxidases in hypertension.
Hypertension
The polymorphonuclear leukocyte contributes to the development of hypertension in the Sabra rat.
Hypertension
The protective effect of Apocynin on Cyclosporine A-induced hypertension and nephrotoxicity in rats.
Hypertension
Time course involvement of matrix metalloproteinases in the vascular alterations of renovascular hypertension.
Hypertension
TMEM16A Contributes to Endothelial Dysfunction by Facilitating Nox2 NADPH Oxidase-Derived Reactive Oxygen Species Generation in Hypertension.
Hypertension
Tumor necrosis factor-alpha: a possible priming agent for the polymorphonuclear leukocyte-reduced nicotinamide-adenine dinucleotide phosphate oxidase in hypertension.
Hypertension
Upregulation of Nox1 in vascular smooth muscle leads to impaired endothelium-dependent relaxation via eNOS uncoupling.
Hypertension
Vaccarin alleviates hypertension and nephropathy in renovascular hypertensive rats.
Hypertension
[Effect of NADPH oxidase activity inhibitor apocynin on blood pressure in rats exposed to chronic intermittent hypoxia and the possible mechanisms]
Hypertension
[Genetic risk factors for ischemic cerebrovascular disease--analysis on fifteen candidate prothrombotic gene polymorphisms in the Japanese population]
Hypertension
[Influence of polymorphism's of endothelial nitric oxide synthase gene and polymorphism of NADPH oxidase gene on development of complications of arterial hypertension]
Hypertension, Portal
NADPH oxidase 1/4 inhibition attenuates the portal hypertensive syndrome via modulation of mesenteric angiogenesis and arterial hyporeactivity in rats.
Hypertension, Pregnancy-Induced
Uncoupled endothelial nitric oxide synthase and oxidative stress in a rat model of pregnancy-induced hypertension.
Hypertension, Pulmonary
Augmented pulmonary vasoconstrictor reactivity following chronic hypoxia requires Src kinase and EGFR signaling.
Hypertension, Pulmonary
Control of vascular smooth muscle function by Src-family kinases and reactive oxygen species in health and disease.
Hypertension, Pulmonary
Cross-Talk between NADPH Oxidase and Autophagy in Pulmonary Artery Endothelial Cells with Intrauterine Persistent Pulmonary Hypertension.
Hypertension, Pulmonary
Cyclic stretch stimulates mitochondrial reactive oxygen species and Nox4 signaling in pulmonary artery smooth muscle cells.
Hypertension, Pulmonary
Hypoxia induces K(v) channel current inhibition by increased NADPH oxidase-derived reactive oxygen species.
Hypertension, Pulmonary
Hypoxic pulmonary hypertension: role of superoxide and NADPH oxidase (gp91phox).
Hypertension, Pulmonary
Increased oxidative stress in lambs with increased pulmonary blood flow and pulmonary hypertension: role of NADPH oxidase and endothelial NO synthase.
Hypertension, Pulmonary
Increased p22(phox)/Nox4 Expression Is Involved in Remodeling Through Hydrogen Peroxide Signaling in Experimental Persistent Pulmonary Hypertension of the Newborn.
Hypertension, Pulmonary
Increased superoxide generation is associated with pulmonary hypertension in fetal lambs: a role for NADPH oxidase.
Hypertension, Pulmonary
Increased Superoxide Production Contributes to the Impaired Angiogenesis of Fetal Pulmonary Arteries with In Utero Pulmonary Hypertension.
Hypertension, Pulmonary
Magnesium lithospermate B prevents phenotypic transformation of pulmonary arteries in rats with hypoxic pulmonary hypertension through suppression of NADPH oxidase.
Hypertension, Pulmonary
NADPH oxidase subunit NOXO1 is a target for emphysema treatment in COPD.
Hypertension, Pulmonary
Perinatal changes in superoxide generation in the ovine lung: Alterations associated with increased pulmonary blood flow.
Hypertension, Pulmonary
Reactive oxygen species and RhoA signaling in vascular smooth muscle: role in chronic hypoxia-induced pulmonary hypertension.
Hypertension, Pulmonary
Reactive oxygen species from NADPH oxidase contribute to altered pulmonary vascular responses in piglets with chronic hypoxia-induced pulmonary hypertension.
Hypertension, Pulmonary
Rosiglitazone Attenuates Chronic Hypoxia-induced Pulmonary Hypertension in a Mouse Model.
Hypertension, Pulmonary
Statins ameliorate pulmonary hypertension secondary to left ventricular dysfunction through the Rho-kinase pathway and NADPH oxidase.
Hypertension, Pulmonary
The role of NADPH oxidase in chronic intermittent hypoxia-induced pulmonary hypertension in mice.
Hypertension, Renovascular
gp91phox-containing NADPH oxidase mediates endothelial dysfunction in renovascular hypertension.
Hyperthyroidism
Superoxide radical generation, NADPH oxidase activity, and cytochrome P-450 content of rat liver microsomal fractions in an experimental hyperthyroid state: relation to lipid peroxidation.
Hypertrophy, Left Ventricular
Downregulation of PPAR? during Experimental Left Ventricular Hypertrophy Is Critically Dependent on Nox2 NADPH Oxidase Signalling.
Hypoglycemia
Control of Insulin Secretion by Production of Reactive Oxygen Species: Study Performed in Pancreatic Islets from Fed and 48-Hour Fasted Wistar Rats.
Hypoglycemia
Hypoglycemic neuronal death is triggered by glucose reperfusion and activation of neuronal NADPH oxidase.
Hypotension
NO mediates the effect of the synthetic natriuretic peptide NPCdc on kidney and aorta in nephrectomised rats.
Hypotension
Tetrahydrobiopterin paradoxically mediates cardiac oxidative stress and mitigates ethanol-evoked cardiac dysfunction in conscious female rats.
Hypotension
The restorative effect of apocynin and catalase in l-arginine induced hypotension on normotensive subjects - the role of oxidative stress.
Hypothyroidism
A Novel Missense Mutation (I26M) in DUOXA2 Causing Congenital Goiter Hypothyroidism Impairs NADPH Oxidase Activity but Not Protein Expression.
Idiopathic Pulmonary Fibrosis
First in Class, Potent, and Orally Bioavailable NADPH Oxidase Isoform 4 (Nox4) Inhibitors for the Treatment of Idiopathic Pulmonary Fibrosis.
Idiopathic Pulmonary Fibrosis
[Increased expression of NADPH oxidase p47-PHOX and p67-PHOX factor in idiopathic pulmonary fibrosis]
Immune System Diseases
Recent Insights into the Biological Functions of Sestrins in Health and Disease.
Immune System Diseases
[Multifocal osteomyelitis as the first manifestation of chronic granulomatous disease]
Infarction, Middle Cerebral Artery
Ischemic stroke injury is reduced in mice lacking a functional NADPH oxidase.
Infarction, Middle Cerebral Artery
Normobaric hyperoxia inhibits NADPH oxidase-mediated matrix metalloproteinase-9 induction in cerebral microvessels in experimental stroke.
Infarction, Middle Cerebral Artery
Normobaric hyperoxia protects the blood brain barrier through inhibiting Nox2 containing NADPH oxidase in ischemic stroke.
Infarction, Middle Cerebral Artery
NOX2 inhibition with apocynin worsens stroke outcome in aged rats.
Infarction, Middle Cerebral Artery
Synergistic Interaction Between Zinc and Reactive Oxygen Species Amplifies Ischemic Brain Injury in Rats.
Infections
A novel missense mutation in the NADPH binding domain of CYBB abolishes the NADPH oxidase activity in a male patient with increased susceptibility to infections.
Infections
A Phaseolus vulgaris NADPH Oxidase Gene Is Required For Root Infection By Rhizobia.
Infections
Acid sphingomyelinase amplifies redox signaling in Pseudomonas aeruginosa-induced macrophage apoptosis.
Infections
Activation of NADPH oxidase is essential, but not sufficient, in controlling intracellular multiplication of Burkholderia pseudomallei in primary human monocytes.
Infections
Adaptive immune defects against glycoantigens in chronic granulomatous disease via dysregulated nitric oxide production.
Infections
Adenosine A(2A) receptor activation limits chronic granulomatous disease-induced hyperinflammation.
Infections
Anaerobic Respiration of NOX1-Derived Hydrogen Peroxide Licenses Bacterial Growth at the Colonic Surface.
Infections
Analysis of Chronic Granulomatous Disease in the Kavkazi Population in Israel Reveals Phenotypic Heterogeneity in Patients with the Same NCF1 mutation (c.579G>A).
Infections
Anaplasma phagocytophilum Dihydrolipoamide Dehydrogenase 1 Affects Host-Derived Immunopathology during Microbial Colonization.
Infections
Anaplasma phagocytophilum modulates gp91phox gene expression through altered interferon regulatory factor 1 and PU.1 levels and binding of CCAAT displacement protein.
Infections
Anaplasma phagocytophilum utilizes multiple host evasion mechanisms to thwart NADPH oxidase-mediated killing during neutrophil infection.
Infections
Association of glucose-6-phosphate dehydrogenase deficiency and X-linked chronic granulomatous disease in a child with anemia and recurrent infections.
Infections
Attenuated Salmonella typhimurium htrA mutants cause fatal infections in mice deficient in NADPH oxidase and destroy NADPH oxidase-deficient macrophage monolayers.
Infections
Autophagy protein Rubicon mediates phagocytic NADPH oxidase activation in response to microbial infection or TLR stimulation.
Infections
B subset cells in patients with chronic granulomatous disease in a Mexican population.
Infections
Bacillus calmette-guerin infection in NADPH oxidase deficiency: defective mycobacterial sequestration and granuloma formation.
Infections
Beta-glucan is a fungal determinant for adhesion-dependent human neutrophil functions.
Infections
Both inducible nitric oxide synthase and NADPH oxidase contribute to the control of virulent phase I Coxiella burnetii infections.
Infections
Caveolin-1 serves as a negative effector in senescent human gingival fibroblasts during Fusobacterium nucleatum infection.
Infections
Changes in the superoxide anion generating capacity and respiratory burst enzymes of peripheral blood monocytes of monkeys during acute Plasmodium knowlesi infection.
Infections
Chronic granulomatous disease, the McLeod phenotype and the contiguous gene deletion syndrome-a review.
Infections
Combined proteomic and transcriptomic analysis of the response of Bacillus anthracis to oxidative stress.
Infections
Commentary: adaptive immunity in the absence of innate immune responses? The un-Tolled truth of the silent invaders.
Infections
Cutting Edge: NOX2 NADPH Oxidase Controls Infection by an Intracellular Bacterial Pathogen through Limiting the Type 1 IFN Response.
Infections
Cytokines, signaling pathways, and effector molecules required for the control of Leishmania (Viannia) braziliensis in mice.
Infections
Cytosolic phospholipase A2-alpha is necessary for platelet-activating factor biosynthesis, efficient neutrophil-mediated bacterial killing, and the innate immune response to pulmonary infection: cPLA2-alpha does not regulate neutrophil NADPH oxidase activity.
Infections
Damage sensing by a Nox-Ask1-MKK3-p38 signaling pathway mediates regeneration in the adult Drosophila midgut.
Infections
Deciphering of the Dual oxidase (Nox family) gene from kuruma shrimp, Marsupenaeus japonicus: full-length cDNA cloning and characterization.
Infections
Dectin-1 Activation during Leishmania amazonensis Phagocytosis Prompts Syk-Dependent Reactive Oxygen Species Production To Trigger Inflammasome Assembly and Restriction of Parasite Replication.
Infections
Dectin-1 Compromises Innate Responses and Host Resistance against Neospora caninum Infection.
Infections
Defective monocyte oxidative burst predicts infection in alcoholic hepatitis and is associated with reduced expression of NADPH oxidase.
Infections
Delayed association of the NADPH oxidase complex with macrophage vacuoles containing the opportunistic pathogen Burkholderia cenocepacia.
Infections
Delineation of the phagocyte NADPH oxidase through studies of chronic granulomatous diseases of childhood.
Infections
Diphenyleneiodonium Inhibits Apoptotic Cell Death of Gastric Epithelial Cells Infected with Helicobacter pylori in a Korean Isolate.
Infections
Distinct signalling mechanisms mediate neutrophil attraction to bacterial infection and tissue injury.
Infections
Dual oxidase 2 and glutathione peroxidase gene expression are elevated in hyperimmunised sheep challenged with Haemonchus contortus.
Infections
Effects of Anaplasma phagocytophilum on host cell ferritin mRNA and protein levels.
Infections
Effects of p47phox C terminus phosphorylations on binding interactions with p40phox and p67phox. Structural and functional comparison of p40phox and p67phox SH3 domains.
Infections
EmrA1 membrane fusion protein of Francisella tularensis?LVS is required for resistance to oxidative stress, intramacrophage survival and virulence in mice.
Infections
Enterobacter cloacae pyomyositis complicating chronic granulomatous disease and review of gram-negative bacilli pyomyositis.
Infections
Expanding the clinical and genetic spectrum of G6PD deficiency: The occurrence of BCGitis and novel missense mutation.
Infections
Expression of NADPH oxidase-dependent resistance to listeriosis in mice occurs during the first 6 to 12 hours of liver infection.
Infections
Fas-associated factor 1 mediates NADPH oxidase-induced reactive oxygen species production and proinflammatory responses in macrophages against Listeria infection.
Infections
Functional interplay between Arabidopsis NADPH oxidases and heterotrimeric G protein.
Infections
Functional Restoration of gp91phox-Oxidase Activity by BAC Transgenesis and Gene Targeting in X-linked Chronic Granulomatous Disease iPSCs.
Infections
Future climate CO2 can harness ROS homeostasis and improve cell wall fortification to alleviate the hazardous effect of Phelipanche infection in pea seedlings.
Infections
Genetic and epigenetic damage induced by reactive nitrogen species: implications in carcinogenesis.
Infections
Health-Related Quality of Life and Emotional Health in X-Linked Carriers of Chronic Granulomatous Disease in the United Kingdom.
Infections
Identification of DUOX1-dependent redox signaling through protein S-glutathionylation in airway epithelial cells.
Infections
Identification of the defective NADPH-oxidase component in chronic granulomatous disease: a study of 57 European families.
Infections
Impaired host defense against Sporothrix schenckii in mice with chronic granulomatous disease.
Infections
In vitro Staphylococcus aureus-induced oxidative stress in mice murine peritoneal macrophages: a duration-dependent approach.
Infections
In vitro time-dependent vancomycin-resistant Staphylococcus aureus-induced free radical generation and status of antioxidant enzymes in murine peritoneal macrophage.
Infections
Influenza Infection Suppresses NADPH Oxidase-Dependent Phagocytic Bacterial Clearance and Enhances Susceptibility to Secondary Methicillin-Resistant Staphylococcus aureus Infection.
Infections
Inhibition of Fatty Acid Oxidation Promotes Macrophage Control of Mycobacterium tuberculosis.
Infections
Inhibitory Effect of ?-Carotene on Helicobacter pylori-Induced TRAF Expression and Hyper-Proliferation in Gastric Epithelial Cells.
Infections
Inhibitory Effects of Antioxidant Reagent in Reactive Oxygen Species Generation and Penetration of Appressoria of Alternaria alternata Japanese Pear Pathotype
Infections
Inhibitory effects of antioxidant reagent in reactive oxygen species generation and penetration of appressoria of Alternaria alternata Japanese pear pathotype.
Infections
Inositol-Requiring Enzyme 1-Dependent Activation of AMPK Promotes Brucella abortus Intracellular Growth.
Infections
Interactions between the components of the human NADPH oxidase: a review about the intrigues in the phox family.
Infections
Intersecting Stories of the Phagocyte NADPH Oxidase and Chronic Granulomatous Disease.
Infections
Intracellular Neutrophil Oxidants: From Laboratory Curiosity to Clinical Reality.
Infections
Leishmania amazonensis amastigotes highly express a tryparedoxin peroxidase isoform that increases parasite resistance to macrophage antimicrobial defenses and Fosters parasite virulence.
Infections
Lipopolysaccharide primes the respiratory burst of Atlantic salmon SHK-1 cells through protein kinase C-mediated phosphorylation of p47phox.
Infections
Listeriolysin O suppresses phospholipase C-mediated activation of the microbicidal NADPH oxidase to promote Listeria monocytogenes infection.
Infections
Live attenuated S. Typhimurium vaccine with improved safety in immuno-compromised mice.
Infections
Localization of the Dual Oxidase BLI-3 and Characterization of Its NADPH Oxidase Domain during Infection of Caenorhabditis elegans.
Infections
Macrophages target Salmonella by Lc3-associated phagocytosis in a systemic infection model.
Infections
Macrophages, but not neutrophils, are critical for proliferation of Burkholderia cenocepacia and ensuing host-damaging inflammation.
Infections
MAMP and DAMP signalling contributes resistance to Fusarium graminearum in Arabidopsis.
Infections
May Dietary Supplementation Augment Respiratory Burst in Wound-site Inflammatory Cells?
Infections
Mechanisms of natural resistance of Balb/c mice to experimental liver amoebiasis.
Infections
MicroRNA-217 suppresses homocysteine-induced proliferation and migration of vascular smooth muscle cells via N-methyl-D-aspartic acid receptor inhibition.
Infections
Mitochondrial Reactive Oxygen Species Enhance Alveolar Macrophage Activity against Aspergillus fumigatus but Are Dispensable for Host Protection.
Infections
Mitogen-activated protein kinase phosphatase 1 (MKP1) negatively regulates the production of Reactive Oxygen Species during Arabidopsis immune responses.
Infections
Molecular cloning and sequencing of Japanese pufferfish (Takifugu rubripes) NADPH oxidase cDNAs.
Infections
Mycobacterial infection induces higher interleukin-1? and dysregulated lung inflammation in mice with defective leukocyte NADPH oxidase.
Infections
NADPH oxidase activation regulates apoptotic neutrophil clearance by murine macrophages.
Infections
NADPH oxidase but not myeloperoxidase protects lymphopenic mice from spontaneous infections.
Infections
NADPH oxidase deficiency results in reduced alveolar macrophage 5-lipoxygenase expression and decreased leukotriene synthesis.
Infections
NADPH oxidase deficient mice develop colitis and bacteremia upon infection with normally avirulent, TTSS-1- and TTSS-2-deficient Salmonella Typhimurium.
Infections
NADPH oxidase depletion in neutrophils from patients with cirrhosis and restoration via toll-like receptor 7/8 activation.
Infections
NADPH oxidase promotes neutrophil extracellular trap formation in pulmonary aspergillosis.
Infections
NADPH oxidases regulate septin-mediated cytoskeletal remodeling during plant infection by the rice blast fungus.
Infections
Neutrophil NADPH oxidase activity in chronic myeloproliferative and myelodysplastic diseases by microscopic and photometric assays.
Infections
Neutrophil pyroptosis mediates pathology of P. aeruginosa lung infection in the absence of the NADPH oxidase NOX2.
Infections
Neutrophil-mediated oxidative burst and host defense are controlled by a Vav-PLCgamma2 signaling axis in mice.
Infections
Nicotinamide effects oxidative burst activity of neutrophils in patients with poorly controlled type 2 diabetes mellitus.
Infections
Nonstructural 3 protein of hepatitis C virus triggers an oxidative burst in human monocytes via activation of NADPH oxidase.
Infections
NOX1/2 activation in human gingival fibroblasts by Fusobacterium nucleatum facilitates attachment of Porphyromonas gingivalis.
Infections
NOX2 Deficiency Permits Sustained Survival of S. aureus in Macrophages and Contributes to Severity of Infection.
Infections
Orange-spotted grouper (Epinephelus coioides) NADPH oxidase: Cloning and expression analysis after Cryptocaryon irritans infection.
Infections
Oxidase activity in cord blood neutrophils: a balance between increased membrane associated cytochrome b558 and deficient cytosolic components.
Infections
p47phox-deficient immune microenvironment signals dysregulate naive T-cell apoptosis.
Infections
Pathogenic Effects of IFIT2 and Interferon-? during Fatal Systemic Candida albicans Infection.
Infections
Peptide inhibition of p22phox and Rubicon interaction as a therapeutic strategy for septic shock.
Infections
Phosphoinositol 3-phosphate acts as a timer for reactive oxygen species production in the phagosome.
Infections
PI(3)P-p40phox binding regulates NADPH oxidase activation in mouse macrophages and magnitude of inflammatory responses in vivo.
Infections
Pivotal Advance: Eosinophilia in the MES rat strain is caused by a loss-of-function mutation in the gene for cytochrome b(-245), alpha polypeptide (Cyba).
Infections
Plant defense factors involved in Olea europaea resistance against Xylella fastidiosa infection.
Infections
Potential dengue virus-triggered apoptotic pathway in human neuroblastoma cells: arachidonic acid, superoxide anion, and NF-kappaB are sequentially involved.
Infections
PPAR{gamma} activation normalizes resolution of acute sterile inflammation in murine chronic granulomatous disease.
Infections
Production of reactive oxygen species is turned on and rapidly shut down in epithelial cells infected with Chlamydia trachomatis.
Infections
Protein disulfide isomerase (PDI) associates with NADPH oxidase and is required for phagocytosis of Leishmania chagasi promastigotes by macrophages.
Infections
Proteomics Landscape of Host-Pathogen Interaction in Acinetobacter baumannii Infected Mouse Lung.
Infections
Rac1 disrupts p67phox/p40phox binding: a novel role for Rac in NADPH oxidase activation.
Infections
Rasamsonia sp: An emerging infection amongst chronic granulomatous disease patients. A case of disseminated infection by a putatively novel Rasamsonia argillacea species complex involving the heart.
Infections
Reactive Oxygen Species-Producing Myeloid Cells Act as a Bone Marrow Niche for Sterile Inflammation-Induced Reactive Granulopoiesis.
Infections
Redox Signaling of NADPH Oxidases Regulates Oxidative Stress Responses, Immunity and Aging.
Infections
Redox Status, JA and ET Signaling Pathway Regulating Responses to Botrytis cinerea Infection Between the Resistant Cucumber Genotype and Its Susceptible Mutant.
Infections
Regulation of alveolar macrophage p40phox: hierarchy of activating kinases and their inhibition by PGE2.
Infections
Regulation of protein kinase CKII by direct interaction with the C-terminal region of p47(phox).
Infections
Residual NADPH oxidase activity and isolated lung involvement in x-linked chronic granulomatous disease.
Infections
Restoration of superoxide generation to a chronic granulomatous disease-derived B-cell line by retrovirus mediated gene transfer.
Infections
Role of inducible nitric oxide synthase and NADPH oxidase in early control of Burkholderia pseudomallei infection in mice.
Infections
Role of NOX Proteins in Pseudomonas aeruginosa Induced Lung Inflammation and Permeability.
Infections
Role of superoxide and reactive nitrogen intermediates in Rhodnius prolixus (Reduviidae)/Trypanosoma rangeli interactions.
Infections
Safety and effectiveness of long-term interferon gamma therapy in patients with chronic granulomatous disease.
Infections
Salmonella pathogenicity island 2-encoded type III secretion system mediates exclusion of NADPH oxidase assembly from the phagosomal membrane.
Infections
Silencing of the Rac1 GTPase MtROP9 in Medicago truncatula stimulates early mycorrhizal and oomycete root colonizations but negatively affects rhizobial infection.
Infections
Small-angle X-ray scattering reveals an extended organization for the autoinhibitory resting state of the p47(phox) modular protein.
Infections
Spontaneous Staphylococcus xylosus Infection in Mice Deficient in NADPH Oxidase and Comparison with Other Laboratory Mouse Strains.
Infections
Sumoylation of nucleoprotein (NP) mediated by activation of NADPH oxidase complex is a consequence of oxidative cellular stress during infection by Infectious salmon anemia (ISA) virus necessary to viral progeny.
Infections
Superoxide production by plant homologues of the gp91(phox) NADPH oxidase. Modulation of activity by calcium and by tobacco mosaic virus infection.
Infections
T3SS effector VopL inhibits the host ROS response, promoting the intracellular survival of Vibrio parahaemolyticus.
Infections
Th17 Cells Provide Mucosal Protection against Gastric Trypanosoma cruzi Infection.
Infections
The active N-terminal region of p67phox. Structure at 1.8 A resolution and biochemical characterizations of the A128V mutant implicated in chronic granulomatous disease.
Infections
The autophagic response to Staphylococcus aureus provides an intracellular niche in neutrophils.
Infections
The circulating immunoglobulins negatively impact on the parasite clearance in the liver of Leishmania donovani-infected mice via dampening ROS activity.
Infections
The effect of captopril on the expression of MMP-9 and the prognosis of neurological function in herpes simplex encephalitis mice.
Infections
The human NADPH oxidase: primary and secondary defects impairing the respiratory burst function and the microbicidal ability of phagocytes.
Infections
The NADPH oxidase AoNoxA in Arthrobotrys oligospora functions as an initial factor in the infection of Caenorhabditis elegans.
Infections
The O-2 Generating NADPH Oxidase of Phagocytes: Structure and Methods of Detection
Infections
The Overactivation of NADPH Oxidase during Clonorchis sinensis Infection and the Exposure to N-Nitroso Compounds Promote Periductal Fibrosis.
Infections
The p47phox deficiency significantly attenuates the pathogenicity of Chlamydia muridarum in the mouse oviduct but not uterine tissues.
Infections
The role of NADH-NADPH oxidase activity in the leukocyte function of burned patients.
Infections
Thymosin ?4 promotes autophagy and repair via HIF-1? stabilization in chronic granulomatous disease.
Infections
Transcriptome analysis of hybrid tilapia (Oreochromis spp.) with Streptococcus agalactiae infection identifies Toll-like receptor pathway-mediated induction of NADPH oxidase complex and piscidins as primary immune-related responses.
Infections
Trichinella spiralis infection affects p47(phox) protein expression in guinea-pig alveolar macrophages.
Infections
Trypanosoma cruzi Needs a Signal Provided by Reactive Oxygen Species to Infect Macrophages.
Infections
Unraveling the role of H3K4 trimethylation and lncRNA HOTAIR in SATB1 and DUSP4-dependent survival of virulent Mycobacterium tuberculosis in macrophages.
Infections
Upregulation of cannabinoid receptor-1 and fibrotic activation of mouse hepatic stellate cells during Schistosoma J. infection: Role of NADPH oxidase.
Infections
Variable correction of host defense following gene transfer and bone marrow transplantation in murine X-linked chronic granulomatous disease.
Infections
Virulent Shigella flexneri causes damage to mitochondria and triggers necrosis in infected human monocyte-derived macrophages.
Infections
Yersinia pseudotuberculosis YopH targets SKAP2-dependent and independent signaling pathways to block neutrophil antimicrobial mechanisms during infection.
Infections
[Effects of respiratory tract infections and antibiotic therapy on NADPH oxidase activity]
Infections
[Interaction of polymorphisms of PPAR-?2 gene -C34G and NADPH oxidase subunit p22phox gene -C242T with Helicobacter pylori infection in esophageal squamous cell carcinoma].
Infections
[Molecular aspects of chronic granulomatous disease. "the NADPH oxidase complex"]
Infections
[The NADPH oxidase activity of pea seedling roots in rhizobial infection depending on abiotic and biotic factors]
Inflammatory Bowel Diseases
Association between a multi-locus genetic risk score and inflammatory bowel disease.
Inflammatory Bowel Diseases
Defects in NADPH Oxidase Genes NOX1 and DUOX2 in Very Early Onset Inflammatory Bowel Disease.
Inflammatory Bowel Diseases
Dexamethasone and Tofacitinib suppress NADPH oxidase expression and alleviate very-early-onset ileocolitis in mice deficient in GSH peroxidase 1 and 2.
Inflammatory Bowel Diseases
In vivo treatment with the herbal phenylethanoid acteoside ameliorates intestinal inflammation in dextran sulphate sodium-induced colitis.
Inflammatory Bowel Diseases
NADPH oxidase complex and IBD candidate gene studies: identification of a rare variant in NCF2 that results in reduced binding to RAC2.
Influenza, Human
Influenza Infection Suppresses NADPH Oxidase-Dependent Phagocytic Bacterial Clearance and Enhances Susceptibility to Secondary Methicillin-Resistant Staphylococcus aureus Infection.
Influenza, Human
Inhibition of Nox2 oxidase activity ameliorates influenza A virus-induced lung inflammation.
Influenza, Human
NADPH Oxidase 1 Is Associated with Altered Host Survival and T Cell Phenotypes after Influenza A Virus Infection in Mice.
Influenza, Human
NADPH oxidases as novel pharmacologic targets against influenza A virus infection.
Influenza, Human
Nox1 oxidase suppresses influenza a virus-induced lung inflammation and oxidative stress.
Influenza, Human
Practical strategies for targeting NF-kappaB and NADPH oxidase may improve survival during lethal influenza epidemics.
Influenza, Human
Superoxide anion production in influenza protein-activated NADPH oxidase of human polymorphonuclear leukocytes.
Insulin Resistance
(-)-Epicatechin and its metabolites prevent palmitate-induced NADPH oxidase upregulation, oxidative stress and insulin resistance in HepG2 cells.
Insulin Resistance
(-)-Epicatechin in the control of glucose homeostasis: Involvement of redox-regulated mechanisms.
Insulin Resistance
(-)-Epicatechin mitigates high-fructose-associated insulin resistance by modulating redox signaling and endoplasmic reticulum stress.
Insulin Resistance
Administration of rosmarinic acid reduces cardiopathology and blood pressure through inhibition of p22phox NADPH oxidase in fructose-fed hypertensive rats.
Insulin Resistance
Advanced oxidation protein products induce inflammatory response and insulin resistance in cultured adipocytes via induction of endoplasmic reticulum stress.
Insulin Resistance
Angiotensin II-induced skeletal muscle insulin resistance mediated by NF-kappaB activation via NADPH oxidase.
Insulin Resistance
Antioxidant treatment prevents the development of fructose-induced abdominal adipose tissue dysfunction.
Insulin Resistance
Argan Oil as an Effective Nutri-Therapeutic Agent in Metabolic Syndrome: A Preclinical Study.
Insulin Resistance
Beneficial effects of argan oil on blood pressure, insulin resistance, and oxidative stress in rat.
Insulin Resistance
Differential effect of amylin on endothelial-dependent vasodilation in mesenteric arteries from control and insulin resistant rats.
Insulin Resistance
Effect of pioglitazone on insulin resistance in fructose-drinking rats correlates with AGEs/RAGE inhibition and block of NADPH oxidase and NF kappa B activation.
Insulin Resistance
Extracts enriched in different polyphenolic families normalize increased cardiac NADPH oxidase expression while having differential effects on insulin resistance, hypertension, and cardiac hypertrophy in high-fructose-fed rats.
Insulin Resistance
FFA-induced hepatic insulin resistance in vivo is mediated by PKC?, NADPH oxidase, and oxidative stress.
Insulin Resistance
Garlic and onion attenuates vascular inflammation and oxidative stress in fructose-fed rats.
Insulin Resistance
Impact of combined exercise training on the development of cardiometabolic and neuroimmune complications induced by fructose consumption in hypertensive rats.
Insulin Resistance
Insulin resistance determines phagocytic nicotinamide adenine dinucleotide phosphate oxidase overactivation in metabolic syndrome patients.
Insulin Resistance
Involvement of oxidative stress and NADPH oxidase activation in the development of cardiovascular complications in a model of insulin resistance, the fructose-fed rat.
Insulin Resistance
L-Arginine supplementation improves insulin sensitivity and beta cell function in the offspring of diabetic rats through AKT and PDX-1 activation.
Insulin Resistance
Low-dose spironolactone reduces reactive oxygen species generation and improves insulin-stimulated glucose transport in skeletal muscle in the TG(mRen2)27 rat.
Insulin Resistance
Mice lacking NOX2 are hyperphagic and store fat preferentially in the liver.
Insulin Resistance
NADPH oxidase activation by hyperglycemia in cardiomyocytes is independent of glucose metabolism but requires SGLT1.
Insulin Resistance
NADPH oxidase contributes to vascular inflammation, insulin resistance, and remodeling in the transgenic (mRen2) rat.
Insulin Resistance
Nox2 contributes to hyperinsulinemia-induced redox imbalance and impaired vascular function.
Insulin Resistance
Nox2 NADPH Oxidase Has a Critical Role in Insulin Resistance-Related Endothelial Cell Dysfunction.
Insulin Resistance
Oral administration of spa-derived green alga improves insulin resistance in overweight subjects: Mechanistic insights from fructose-fed rats.
Insulin Resistance
Renin inhibition attenuates insulin resistance, oxidative stress, and pancreatic remodeling in the transgenic ren2 rat.
Insulin Resistance
Sleep fragmentation promotes NADPH oxidase 2-mediated adipose tissue inflammation leading to insulin resistance in mice.
Insulin Resistance
The antioxidant tempol inhibits cardiac hypertrophy in the insulin-resistant GLUT4-deficient mouse in vivo.
Insulin Resistance
The effects of palmitate on hepatic insulin resistance are mediated by NADPH Oxidase 3-derived reactive oxygen species through JNK and p38MAPK pathways.
Insulin Resistance
The Renin Angiotensin aldosterone system in hypertension: roles of insulin resistance and oxidative stress.
Insulinoma
Apoptosis signal regulating kinase-1 and NADPH oxidase mediate human amylin evoked redox stress and apoptosis in pancreatic beta-cells.
Intervertebral Disc Degeneration
Sparstolonin B prevents lumbar intervertebral disc degeneration through toll like receptor 4, NADPH oxidase activation and the protein kinase B signaling pathway.
Intracranial Aneurysm
Polymorphisms of the NADPH oxidase P22PHOX gene in a Caucasian population with intracranial aneurysms.
Intracranial Arteriosclerosis
Omega-3 fatty acid supplement reduces activation of NADPH oxidase in intracranial atherosclerosis stenosis.
Invasive Pulmonary Aspergillosis
Restoration of anti-Aspergillus defense by neutrophil extracellular traps in human chronic granulomatous disease after gene therapy is calprotectin-dependent.
Invasive Pulmonary Aspergillosis
Restoration of NET formation by gene therapy in CGD controls aspergillosis.
Iron Deficiencies
Dietary iron deficiency induces ventricular dilation, mitochondrial ultrastructural aberrations and cytochrome c release: involvement of nitric oxide synthase and protein tyrosine nitration.
Iron Overload
Chronic iron overload induces functional and structural vascular changes in small resistance arteries via NADPH oxidase-dependent O2(-) production.
Ischemic Attack, Transient
Normobaric hyperoxia inhibits NADPH oxidase-mediated matrix metalloproteinase-9 induction in cerebral microvessels in experimental stroke.
Ischemic Stroke
Apocynin attenuates cerebral infarction after transient focal ischaemia in rats.
Ischemic Stroke
Deficiency in the voltage-gated proton channel Hv1 increases M2 polarization of microglia and attenuates brain damage from photothrombotic ischemic stroke.
Ischemic Stroke
Early increase of Nox4 NADPH oxidase and superoxide generation following endothelin-1-induced stroke in conscious rats.
Ischemic Stroke
Inhibition of gp91(phox) contributes towards normobaric hyperoxia afforded neuroprotection in focal cerebral ischemia.
Ischemic Stroke
Ischemic stroke injury is reduced in mice lacking a functional NADPH oxidase.
Ischemic Stroke
NADPH oxidase and angiogenesis following endothelin-1 induced stroke in rats: role for nox2 in brain repair.
Ischemic Stroke
NADPH Oxidase as a Therapeutic Target for Neuroprotection against Ischaemic Stroke: Future Perspectives.
Ischemic Stroke
Normobaric hyperoxia inhibits NADPH oxidase-mediated matrix metalloproteinase-9 induction in cerebral microvessels in experimental stroke.
Ischemic Stroke
Normobaric hyperoxia protects the blood brain barrier through inhibiting Nox2 containing NADPH oxidase in ischemic stroke.
Ischemic Stroke
NOX2 deficiency ameliorates cerebral injury through reduction of complexin II-mediated glutamate excitotoxicity in experimental stroke.
Ischemic Stroke
Pathophysiology and Therapeutic Potential of NADPH Oxidases in Ischemic Stroke-Induced Oxidative Stress.
Ischemic Stroke
Pathophysiology and treatments of oxidative injury in ischemic stroke: focus on the phagocytic NADPH oxidase (NOX) 2.
Ischemic Stroke
Role of NADPH Oxidase-Induced Hypoxia-Induced Factor-1? Increase in Blood-Brain Barrier Disruption after 2-Hour Focal Ischemic Stroke in Rat.
Ischemic Stroke
The 2-(2-benzofuranyl)-2-imidazoline provides neuroprotection against focal cerebral ischemia-reperfusion injury in diabetic rats: Influence of microglia and possible mechanisms of action.
Joint Instability
Genetic dissection of canine hip dysplasia phenotypes and osteoarthritis reveals three novel loci.
Kidney Calculi
NADPH oxidase as a therapeutic target for oxalate induced injury in kidneys.
Kidney Diseases
A Synthetic Peptide from Transforming Growth Factor-?1 Type III Receptor Inhibits NADPH Oxidase and Prevents Oxidative Stress in the Kidney of Spontaneously Hypertensive Rats.
Kidney Diseases
Asymmetric dimethylarginine and reactive oxygen species: unwelcome twin visitors to the cardiovascular and kidney disease tables.
Kidney Diseases
Hydrogen peroxide derived from NADPH oxidase 4- and 2 contributes to the endothelium-dependent vasodilatation of intrarenal arteries.
Kidney Diseases
NADPH oxidase 4 promotes cisplatin-induced acute kidney injury via ROS-mediated programmed cell death and inflammation.
Kidney Diseases
Recent Insights into the Biological Functions of Sestrins in Health and Disease.
Kidney Failure, Chronic
Ayurvedic medicine and NADPH oxidase: a possible approach to the prevention of ESRD in hyperoxaluria.
Kidney Failure, Chronic
Depressed phagocytosis in hemodialyzed patients: in vivo and in vitro mechanisms.
Kidney Failure, Chronic
Polymorphisms in NADPH oxidase CYBA gene modify the risk of ESRD in patients with chronic glomerulonephritis.
Kidney Failure, Chronic
Relation between development of cardiovascular disease and the C242T CYBA polymorphism of the NADPH oxidase in ESRD patients.
Kidney Failure, Chronic
[Effects of Jianpi Qinghua Recipe on angiotensin II/NADPH oxidase pathway in 5/6 nephrectomized rats].
Kidney Neoplasms
Nox4 inhibition enhances the cytotoxicity of cisplatin in human renal cancer cells.
Leiomyoma
Reactive Oxygen Species Mediate Mitogenic Growth Factor Signaling Pathways in Human Leiomyoma Smooth Muscle Cells.
Leukemia
15d-PGJ2 induces apoptosis by reactive oxygen species-mediated inactivation of Akt in leukemia and colorectal cancer cells and shows in vivo antitumor activity.
Leukemia
Bifidobacterium breve - HT-29 cell line interaction: modulation of TNF-? induced gene expression.
Leukemia
Development of the superoxide-generating system during differentiation of the HL-60 human promyelocytic leukemia cell line.
Leukemia
Glucocorticoid-induced apoptotic pathways in eosinophils: comparison with glucocorticoid-sensitive leukemia cells.
Leukemia
Induction of cytosolic activation factor for NADPH oxidase in differentiated HL-60 leukemia cells.
Leukemia
Isolation and characterization of a variant HL60 cell line defective in the activation of the NADPH oxidase by phorbol myristate acetate.
Leukemia
Letter by Wang Regarding Article, "Megakaryocytic Leukemia 1 Bridges Epigenetic Activation of NADPH Oxidase in Macrophages to Cardiac Ischemia-Reperfusion Injury".
Leukemia
NADPH oxidase-mediated generation of reactive oxygen species is critically required for survival of undifferentiated human promyelocytic leukemia cell line HL-60.
Leukemia
Pigment epithelium-derived factor (PEDF) inhibits survival and proliferation of VEGF-exposed multiple myeloma cells through its anti-oxidative properties.
Leukemia
PML/RARalpha fusion protein mediates the unique sensitivity to arsenic cytotoxicity in acute promyelocytic leukemia cells: Mechanisms involve the impairment of cAMP signaling and the aberrant regulation of NADPH oxidase.
Leukemia
Progression and inflammation of human myeloid leukemia induced by ambient PM2.5 exposure.
Leukemia
Response by Li and Xu to Letter Regarding Article, "Megakaryocytic Leukemia 1 Bridges Epigenetic Activation of NADPH Oxidase in Macrophages to Cardiac Ischemia-Reperfusion Injury".
Leukemia
Role of oxygen radicals generated by NADPH oxidase in apoptosis induced in human leukemia cells.
Leukemia
The role of Rac2-NADPH oxidase-ROS in human leukemia HL-60 cell apoptosis induced by diallyl disulfide.
Leukemia
Transcriptional activation of the gp91phox NADPH oxidase subunit by TPA in HL-60 cells.
Leukemia
Tumor necrosis factor and immune interferon synergistically induce cytochrome b-245 heavy-chain gene expression and nicotinamide-adenine dinucleotide phosphate hydrogenase oxidase in human leukemic myeloid cells.
Leukemia
Zerumbone, a Southeast Asian ginger sesquiterpene, markedly suppresses free radical generation, proinflammatory protein production, and cancer cell proliferation accompanied by apoptosis: the alpha,beta-unsaturated carbonyl group is a prerequisite.
Leukemia, Megakaryoblastic, Acute
Megakaryocytic Leukemia 1 (MKL1) Bridges Epigenetic Activation of NADPH Oxidase in Macrophages to Cardiac Ischemia-Reperfusion Injury.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Inhibition of the NADPH oxidase regulates heme oxygenase 1 expression in chronic myeloid leukemia.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Studies on granulocyte functions in patients with chronic myeloid leukemia.
Leukemia, Myeloid
Pharmacological targeting of ROS reaction network in myeloid leukemia cells monitored by ultra-weak photon emission.
Leukemia, Myeloid
Role of NADPH oxidase in arsenic-induced reactive oxygen species formation and cytotoxicity in myeloid leukemia cells.
Leukemia, Myeloid, Acute
Characterization of NADPH Oxidase Expression and Activity in Acute Myeloid Leukemia Cell Lines: A Correlation with the Differentiation Status.
Leukemia, Myeloid, Acute
Impact of NADPH oxidase functional polymorphisms in acute myeloid leukemia induction chemotherapy.
Leukemia, Promyelocytic, Acute
PML/RARalpha fusion protein mediates the unique sensitivity to arsenic cytotoxicity in acute promyelocytic leukemia cells: Mechanisms involve the impairment of cAMP signaling and the aberrant regulation of NADPH oxidase.
Leukemia, Promyelocytic, Acute
Zerumbone, a Southeast Asian ginger sesquiterpene, markedly suppresses free radical generation, proinflammatory protein production, and cancer cell proliferation accompanied by apoptosis: the alpha,beta-unsaturated carbonyl group is a prerequisite.
Leukocyte-Adhesion Deficiency Syndrome
Defective priming of the phagocyte oxidative burst in a child with recurrent intracellular infections.
Liver Abscess
Autosomal recessive chronic granulomatous disease with absence of the 67-kD cytosolic NADPH oxidase component: identification of mutation and detection of carriers.
Liver Cirrhosis
Effects of Losartan on Hepatic Expression of Non-phagocytic NADPH Oxidase and Fibrogenic Genes in Patients with Chronic Hepatitis C.
Liver Cirrhosis
NADPH oxidase 5 promotes proliferation and fibrosis in human hepatic stellate cells.
Liver Cirrhosis
NADPH oxidase NOX4 mediates stellate cell activation and hepatocyte cell death during liver fibrosis development.
Liver Cirrhosis
NADPH oxidase signal transduces angiotensin II in hepatic stellate cells and is critical in hepatic fibrosis.
Liver Cirrhosis
NADPH Oxidase Signaling Pathway Mediates Mesenchymal Stem Cell-Induced Inhibition of Hepatic Stellate Cell Activation.
Liver Cirrhosis
Nicotinamide adenine dinucleotide phosphate oxidase (nox) in experimental liver fibrosis: GKT137831 as a novel potential therapeutic agent.
Liver Cirrhosis
Phagocytosis of apoptotic bodies by hepatic stellate cells induces NADPH oxidase and is associated with liver fibrosis in vivo.
Liver Cirrhosis
Sustained activation of Rac1 in hepatic stellate cells promotes liver injury and fibrosis in mice.
Liver Cirrhosis
The potential antifibrotic impact of apocynin and alpha-lipoic acid in concanavalin A-induced liver fibrosis in rats: Role of NADPH oxidases 1 and 4.
Liver Diseases
Association between the CYBA and NOX4 genes of NADPH oxidase and its relationship with metabolic syndrome in non-alcoholic fatty liver disease in Brazilian population.
Liver Diseases
Hepatitis C Viral Proteins induce NADPH Oxidase 4 (Nox4) in a TGF{beta}-dependent manner: A new contributor of HCV-induced oxidative stress.
Liver Diseases
The NOX1 isoform of NADPH oxidase is involved in dysfunction of liver sinusoids in nonalcoholic fatty liver disease.
Liver Diseases
[Effects of sequoyitol on expression of NADPH oxidase subunits p22 phox and p47 phox in rats with type 2 diabetic liver disease].
Liver Diseases, Alcoholic
Oxidative stress in alcoholic liver disease: role of NADPH oxidase complex.
Liver Neoplasms
The NADPH oxidase inhibitor VAS2870 impairs cell growth and enhances TGF-?-induced apoptosis of liver tumor cells.
Liver Neoplasms
The NADPH oxidase NOX4 inhibits hepatocyte proliferation and liver cancer progression.
Liver Neoplasms
Vitamin E down-modulates iNOS and NADPH oxidase in c-Myc/TGF-alpha transgenic mouse model of liver cancer.
Lung Diseases
Recent Insights into the Biological Functions of Sestrins in Health and Disease.
Lung Diseases
Regulation of NADPH Oxidase in Vascular Endothelium: The Role of Phospholipases, Protein Kinases, and Cytoskeletal Proteins.
Lung Diseases, Interstitial
[A clinical study of haploid hematopoietic stem cells combined with third-party umbilical cord blood transplantation in the treatment of chronic granulomatous disease].
Lung Injury
A Peptide Inhibitor of NADPH Oxidase (NOX2) Activation Markedly Decreases Mouse Lung Injury and Mortality Following Administration of Lipopolysaccharide (LPS).
Lung Injury
Acid aspiration-induced lung inflammation and injury are exacerbated in NADPH oxidase-deficient mice.
Lung Injury
Aprotinin attenuated ischemia-reperfusion injury in an isolated rat lung model after 18-hours preservation.
Lung Injury
Correction: Fisher, Aron B., et al. A Peptide Inhibitor of NADPH Oxidase (NOX2) Activation Markedly Decreases Mouse Lung Injury and Mortality Following Administration of Lipopolysaccharide (LPS). Int. J. Mol. Sci. 2019, 20, 2395.
Lung Injury
Dynamin 2 and c-Abl are novel regulators of hyperoxia-mediated NADPH oxidase activation and ROS production in caveolin-enriched microdomains of the endothelium.
Lung Injury
Effect of NADPH oxidase inhibition on cardiopulmonary bypass-induced lung injury.
Lung Injury
Effect of the NADPH oxidase inhibitor apocynin on ischemia-reperfusion lung injury.
Lung Injury
Effect of the NADPH oxidase inhibitor apocynin on septic lung injury in guinea pigs.
Lung Injury
In Vivo evidence of free radical generation in the mouse lung after exposure to Pseudomonas Aeruginosa bacterium: An ESR spin-trapping investigation.
Lung Injury
Inhibition of the phospholipase A2 activity of peroxiredoxin 6 prevents lung damage with exposure to hyperoxia.
Lung Injury
Is Nox4 a key regulator of the activated state of fibroblasts in systemic sclerosis?
Lung Injury
Ischemia-reperfusion lung injury is prevented by apocynin, a novel inhibitor of leukocyte NADPH oxidase.
Lung Injury
NADPH oxidase-dependent reactive oxygen species mediate amplified TLR4 signaling and sepsis-induced mortality in Nrf2-deficient mice.
Lung Injury
Neutrophil extracellular traps promote cadmium chloride-induced lung injury in mice.
Lung Injury
Novel role for non-muscle MLCK in hyperoxia-induced recruitment of cytoskeletal proteins, NADPH oxidase activation and reactive oxygen species generation in lung endothelium.
Lung Injury
Preservation of complement-induced lung injury in mice with deficiency of NADPH oxidase.
Lung Injury
Protection against LPS-induced acute lung injury by a mechanism-based inhibitor of NADPH oxidase (type 2).
Lung Injury
Regulation of NADPH Oxidase in Vascular Endothelium: The Role of Phospholipases, Protein Kinases, and Cytoskeletal Proteins.
Lung Neoplasms
Antitumor activity of BJ-1207, a 6-amino-2,4,5-trimethylpyridin-3-ol derivative, in human lung cancer.
Lung Neoplasms
Association between NADPH oxidase (NOX) and lung cancer: a systematic review and meta-analysis.
Lung Neoplasms
C609T Polymorphism of NADPH Quinone Oxidoreductase 1 Correlates Clinical Hematological Toxicities in Lung Cancer Patients Treated with Amrubicin.
Lung Neoplasms
Dual inhibition of NOX2 and receptor tyrosine kinase by BJ-1301 enhances anticancer therapy efficacy via suppression of autocrine stimulatory factors in lung cancer.
Lung Neoplasms
Dysregulated Redox Regulation Contributes to Nuclear EGFR Localization and Pathogenicity in Lung Cancer.
Lung Neoplasms
Glutathione S-transferase P1 and NADPH quinone oxidoreductase polymorphisms are associated with aberrant promoter methylation of P16(INK4a) and O(6)-methylguanine-DNA methyltransferase in sputum.
Lung Neoplasms
Grape seed proanthocyanidins inhibit cigarette smoke condensate-induced lung cancer cell migration through inhibition of NADPH oxidase and reduction in the binding of p22(phox) and p47(phox) proteins.
Lung Neoplasms
Inhibition of NADPH oxidase protects against metastasis of human lung cancer by decreasing microRNA-21.
Lung Neoplasms
Lack of association between NADPH quinone oxidoreductase 1 (NQO1) gene C609T polymorphism and lung cancer: a case-control study and a meta-analysis.
Lung Neoplasms
NADPH oxidase 1-dependent ROS is crucial for TLR4 signaling to promote tumor metastasis of non-small cell lung cancer.
Lung Neoplasms
Pivotal Role of Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 in Inflammatory Pulmonary Diseases.
Lung Neoplasms
Sevoflurane Effect on Cognitive Function and the Expression of Oxidative Stress Response Proteins in Elderly Patients undergoing Radical Surgery for Lung Cancer.
Lung Neoplasms
Tight junction protein 1 is regulated by Transforming growth factor ? and contributes to cell motility in NSCLC cells.
Lupus Erythematosus, Systemic
207 Structural basis of the effect of systemic lupus erythematosus (SLE)-associated mutations on the activity of NADPH oxidase.
Lupus Erythematosus, Systemic
Allelic heterogeneity in NCF2 associated with systemic lupus erythematosus (SLE) susceptibility across four ethnic populations.
Lupus Erythematosus, Systemic
Haploinsufficiency of NADPH Oxidase Subunit Neutrophil Cytosolic Factor 2 Is Sufficient to Accelerate Full-Blown Lupus in NZM 2328 Mice.
Lupus Erythematosus, Systemic
Lupus and proliferative nephritis are PAD4 independent in murine models.
Lupus Erythematosus, Systemic
NADPH oxidase inhibits the pathogenesis of systemic lupus erythematosus.
Lupus Erythematosus, Systemic
NCF1-339 polymorphism is associated with altered formation of neutrophil extracellular traps, high serum interferon activity and antiphospholipid syndrome in systemic lupus erythematosus.
Lupus Erythematosus, Systemic
The behavior of neutrophil extracellular traps and NADPH oxidative activity in pediatric systemic lupus erythematosus: relation to disease activity and lupus nephritis.
Lupus Nephritis
NADPH oxidase and nitric oxide synthase-dependent superoxide production is increased in proliferative lupus nephritis.
Lyme Disease
Bb2Bb3 regulation of murine Lyme arthritis is distinct from Ncf1 and independent of the phagocyte nicotinamide adenine dinucleotide phosphate oxidase.
Lymphohistiocytosis, Hemophagocytic
Undiagnosed Chronic Granulomatous Disease, Burkholderia cepacia complex Pneumonia, and Acquired Hemophagocytic Lymphohistiocytosis: A Deadly Association.
Lymphoma
Regression of Diffuse B-cell Lymphoma of the Leg with Intralesional Gentian Violet.
Lymphoma
The NADPH oxidase NOX5 protects against apoptosis in ALK-positive anaplastic large-cell lymphoma cell lines.
Lymphoma
Vaccarin alleviates hypertension and nephropathy in renovascular hypertensive rats.
Lymphoma, B-Cell
Association of NADPH oxidase polymorphisms with anthracycline-induced cardiotoxicity in the RICOVER-60 trial of patients with aggressive CD20(+) B-cell lymphoma.
Lymphoma, B-Cell
Influence of Delphinidin-3-glucoside on Oxidized Low-Density Lipoprotein-Induced Oxidative Stress and Apoptosis in Cultured Endothelial Cells.
Lymphoma, B-Cell
Vaccarin alleviates hypertension and nephropathy in renovascular hypertensive rats.
Lymphoma, Large-Cell, Anaplastic
The NADPH oxidase NOX5 protects against apoptosis in ALK-positive anaplastic large-cell lymphoma cell lines.
Lymphoma, T-Cell
Roles of GTP and Rho GTPases in pancreatic islet beta cell function and dysfunction.
Malaria
Characterization of a candidate locus for malaria susceptibility in human populations: a (TA)n microsatellite in the promoter region of the CYBB gene, the gp91 phox subunit of the NADPH oxidase.
Malaria
DNA phasing by TA dinucleotide microsatellite length determines in vitro and in vivo expression of the gp91phox subunit of NADPH oxidase and mediates protection against severe malaria.
Malaria
Phagocyte-derived reactive oxygen species do not influence the progression of murine blood-stage malaria infections.
Malnutrition
Long-term effects of intrauterine malnutrition on vascular function in female offspring: implications of oxidative stress.
Malnutrition
NADPH oxidase and enhanced superoxide generation in intrauterine undernourished rats: involvement of the renin-angiotensin system.
Malnutrition
TRPC3-Based Protein Signaling Complex as a Therapeutic Target of Myocardial Atrophy.
Marfan Syndrome
Redox stress in Marfan syndrome: Dissecting the role of the NADPH oxidase NOX4 in aortic aneurysm.
Mastitis
Cloning and sequencing of the bovine flavocytochrome b subunit proteins, gp91-phox and p22-phox: comparison with other known flavocytochrome b sequences.
Mastitis
The role of NADPH oxidase in taurine attenuation of Streptococcus uberis-induced mastitis in rats.
Melanoma
Corrigendum to "Proopiomelanocortin gene delivery induces apoptosis in melanoma through NADPH oxidase 4-mediated ROS generation" [Free Radic. Biol. Med. 70 (2014) 14-22].
Melanoma
Effects of hyperbaric oxygen on NLRP3 inflammasome activation in the brain after carbon monoxide poisoning.
Melanoma
Interleukin-8 (IL-8), melanoma growth-stimulatory activity, and neutrophil-activating peptide selectively mediate priming of the neutrophil NADPH oxidase through the type A or type B IL-8 receptor.
Melanoma
Metabolic utilization of exogenous pyruvate by mutant p53(R175H) human melanoma cells promotes survival under glucose depletion.
Melanoma
Overexpression of Ras-Related C3 Botulinum Toxin Substrate 2 Radiosensitizes Melanoma Cells In Vitro and In Vivo.
Melanoma
Proopiomelanocortin gene delivery induces apoptosis in melanoma through NADPH oxidase 4-mediated ROS generation.
Melanoma
Regression of Diffuse B-cell Lymphoma of the Leg with Intralesional Gentian Violet.
Melanoma, Experimental
Inhibition of NADPH oxidase activity promotes differentiation of B16 melanoma cells.
Melioidosis
Caspase-11-dependent pyroptosis of lung epithelial cells protects from melioidosis while caspase-1 mediates macrophage pyroptosis and production of IL-18.
Melioidosis
Role of inducible nitric oxide synthase and NADPH oxidase in early control of Burkholderia pseudomallei infection in mice.
Memory Disorders
Attenuation of Brain Damage and Cognitive Impairment by Direct Renin Inhibition in Mice With Chronic Cerebral Hypoperfusion.
Memory Disorders
Inhibition of NADPH oxidase by apocynin prevents learning and memory deficits in a mouse Parkinson's disease model.
Memory Disorders
Protective effect of resveratrol against chronic intermittent hypoxia-induced spatial memory deficits, hippocampal oxidative DNA damage and increased p47Phox NADPH oxidase expression in young rats.
Meningitis, Pneumococcal
Myeloid Src kinases regulate phagocytosis and oxidative burst in pneumococcal meningitis by activating NADPH oxidase.
Mesothelioma
Diarachidonoylphosphoethanolamine induces apoptosis of malignant pleural mesothelioma cells through a Trx/ASK1/p38 MAPK pathway.
Mesothelioma, Malignant
Diarachidonoylphosphoethanolamine induces apoptosis of malignant pleural mesothelioma cells through a Trx/ASK1/p38 MAPK pathway.
Metabolic Diseases
Genetic Deletion of NADPH Oxidase 1 Rescues Microvascular Function in Mice With Metabolic Disease.
Metabolic Diseases
Hyperhomocysteinemia, a cardiac metabolic disease: role of nitric oxide and the p22phox subunit of NADPH oxidase.
Metabolic Diseases
Modulation of mitochondria and NADPH oxidase function by the nitrate-nitrite-NO pathway in metabolic disease with focus on type 2 diabetes.
Metabolic Syndrome
Activated glycine receptors may decrease endosomal NADPH oxidase activity by opposing ClC-3-mediated efflux of chloride from endosomes.
Metabolic Syndrome
Angiotensin receptor-mediated oxidative stress is associated with impaired cardiac redox signaling and mitochondrial function in insulin-resistant rats.
Metabolic Syndrome
Association between the CYBA and NOX4 genes of NADPH oxidase and its relationship with metabolic syndrome in non-alcoholic fatty liver disease in Brazilian population.
Metabolic Syndrome
Emerging Role of Oxidative Stress in Metabolic Syndrome and Cardiovascular Diseases: Important Role of Rac/NADPH Oxidase.
Metabolic Syndrome
G allele of the -930A>G polymorphism of the CYBA gene is associated with insulin resistance in obese subjects.
Metabolic Syndrome
High fructose consumption combined with low dietary magnesium intake may increase the incidence of the metabolic syndrome by inducing inflammation.
Metabolic Syndrome
Hyperglycemia-Mediated Oxidative Stress Increases Pulmonary Vascular Permeability.
Metabolic Syndrome
Is oxidative stress of adipocytes a cause or a consequence of the metabolic syndrome?
Metabolic Syndrome
NADPH Oxidase Activity in Cerebral Arterioles Is a Key Mediator of Cerebral Small Vessel Disease-Implications for Prevention.
Metabolic Syndrome
Neovascular deterioration, impaired NADPH oxidase and inflammatory cytokine expression in adipose-derived multipotent cells from subjects with metabolic syndrome.
Metabolic Syndrome
Phagocytic NADPH oxidase overactivity underlies oxidative stress in metabolic syndrome.
Metabolic Syndrome
Reactive Oxygen Species from NADPH Oxidase and Mitochondria Participate in the Proliferation of Aortic Smooth Muscle Cells from a Model of Metabolic Syndrome.
Metabolic Syndrome
Renin inhibition improves metabolic syndrome, and reduces angiotensin II levels and oxidative stress in visceral fat tissues in fructose-fed rats.
Metabolic Syndrome
Spirulina platensis and silicon-enriched spirulina equally improve glucose tolerance and decrease the enzymatic activity of hepatic NADPH oxidase in obesogenic diet-fed rats.
Mitral Valve Insufficiency
Atrial myocardial nox2 containing NADPH oxidase activity contribution to oxidative stress in mitral regurgitation: potential mechanism for atrial remodeling.
Mouth Neoplasms
NADPH oxidase 5? promotes the formation of CD271 tumor-initiating cells in oral cancer.
Mucositis
Potential role of the NADPH oxidase NOX1 in the pathogenesis of 5-fluorouracil-induced intestinal mucositis in mice.
Multiple Myeloma
Pigment epithelium-derived factor (PEDF) inhibits survival and proliferation of VEGF-exposed multiple myeloma cells through its anti-oxidative properties.
Multiple Sclerosis
Aging-Exacerbated Acute Axon and Myelin Injury Is Associated with Microglia-Derived Reactive Oxygen Species and Is Alleviated by the Generic Medication Indapamide.
Multiple Sclerosis
Erratum: Persistent activation of microglia and NADPH oxidase drive hippocampal dysfunction in experimental multiple sclerosis.
Multiple Sclerosis
Inhibition of NADPH oxidase activation reduces EAE-induced white matter damage in mice.
Multiple Sclerosis
Microglial Hv1 proton channel promotes cuprizone-induced demyelination through oxidative damage.
Multiple Sclerosis
NADPH oxidase expression in active multiple sclerosis lesions in relation to oxidative tissue damage and mitochondrial injury.
Multiple Sclerosis
Pathogenic Effects of IFIT2 and Interferon-? during Fatal Systemic Candida albicans Infection.
Multiple Sclerosis
Serum NADPH oxidase concentrations and the associations with iron metabolism in relapsing remitting multiple sclerosis.
Multiple Sclerosis, Relapsing-Remitting
Serum NADPH oxidase concentrations and the associations with iron metabolism in relapsing remitting multiple sclerosis.
Muscle Cramp
Neutrophil antimicrobial defense against Staphylococcus aureus is mediated by phagolysosomal but not extracellular trap-associated cathelicidin.
Muscular Atrophy
Genetic ablation of 12/15-lipoxygenase but not 5-lipoxygenase protects against denervation-induced muscle atrophy.
Muscular Dystrophies
Absence of Dystrophin Disrupts Skeletal Muscle Signaling: Roles of Ca2+, Reactive Oxygen Species, and Nitric Oxide in the Development of Muscular Dystrophy.
Muscular Dystrophies
Elevation of the level of thiobarbituric acid-reactive products in hindleg skeletal muscle of dystrophic mice, but non-elevation in tongue muscle.
Mycobacterium Infections
In Silico Model of Vitamin D3 Dependent NADPH Oxidase Complex Activation During Mycobacterium Infection.
Mycoses
Characterization of the defense transcriptome responsive to Fusarium oxysporum-infection in Arabidopsis using RNA-seq.
Mycoses
Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease.
Mycoses
Effect of amphotericin B and micafungin combination on survival, histopathology, and fungal burden in experimental aspergillosis in the p47phox-/- mouse model of chronic granulomatous disease.
Mycoses
Impaired macrophage function following bacterial stimulation in chronic granulomatous disease.
Mycoses
Monocyte- and Macrophage-Targeted NADPH Oxidase Mediates Antifungal Host Defense and Regulation of Acute Inflammation in Mice.
Mycoses
NADPH oxidase controls pulmonary neutrophil infiltration in the response to fungal cell walls by limiting LTB4.
Mycoses
PtdIns3P binding to the PX domain of p40phox is a physiological signal in NADPH oxidase activation.
Mycoses
Respiratory complications after haematopoietic stem cell transplantation in a patient with chronic granulomatous disease.
Mycoses
Safety and Efficacy of Ustekinumab in the Inflammatory Bowel Disease of Chronic Granulomatous Disease.
Mycoses
Severe glucose-6-phosphate dehydrogenase deficiency leads to susceptibility to infection and absent NETosis.
Mycoses
The search for a genetic defect in Polish patients with chronic granulomatous disease.
Mycoses
Xanthine oxidase contributes to host defense against Burkholderia cepacia in the p47(phox-/-) mouse model of chronic granulomatous disease.
Mycoses
[Chronic granulomatous disease (CGD): dysfunction of the neutrophil granulocyte NADPH-oxidase enzyme system]
Mycoses
[Clinical and molecular inflammatory alterations in chronic granulomatous disease].
myeloperoxidase deficiency
Identification of a subgroup of myelodysplastic patients with a neutrophil stimulation-signalling defect.
Myeloproliferative Disorders
Increased reactive oxygen species production and p47phox phosphorylation in neutrophils from myeloproliferative disorders patients with JAK2 (V617F) mutation.
Myeloproliferative Disorders
Neutrophil NADPH oxidase activity in chronic myeloproliferative and myelodysplastic diseases by microscopic and photometric assays.
Myocardial Infarction
Activation of NADPH oxidase mediates increased endoplasmic reticulum stress and left ventricular remodeling after myocardial infarction in rabbits.
Myocardial Infarction
Angiotensin-converting enzyme and p22(phox) polymorphisms and the risk of coronary heart disease in a low-risk Spanish population.
Myocardial Infarction
Beneficial effects of benfotiamine, a NADPH oxidase inhibitor, in isoproterenol-induced myocardial infarction in rats.
Myocardial Infarction
Cardiomyocyte-specific overexpression of an active form of Rac predisposes the heart to increased myocardial stunning and ischemia-reperfusion injury.
Myocardial Infarction
Differential effects of NADPH oxidase and xanthine oxidase inhibition on sympathetic reinnervation in postinfarct rat hearts.
Myocardial Infarction
Effects of Late Aerobic Exercise on Cardiac Remodeling of Rats with Small-Sized Myocardial Infarction.
Myocardial Infarction
Exercise preconditioning of myocardial infarct size in dogs is triggered by calcium.
Myocardial Infarction
Expression of p22-phox and gp91-phox, essential components of NADPH oxidase, increases after myocardial infarction.
Myocardial Infarction
Influence of N- acetylcysteine on oxidative stress in slow-twitch soleus muscle of heart failure rats.
Myocardial Infarction
Inhibition of NADPH oxidase reduces myocardial oxidative stress and apoptosis and improves cardiac function in heart failure after myocardial infarction.
Myocardial Infarction
Involvement of Nox2 NADPH oxidase in adverse cardiac remodeling after myocardial infarction.
Myocardial Infarction
Left ventricular remodeling after myocardial infarction in mice with targeted deletion of the NADPH oxidase subunit gp91(PHOX).
Myocardial Infarction
Nitrite confers protection against myocardial infarction: Role of xanthine oxidoreductase, NADPH oxidase and K(ATP) channels.
Myocardial Infarction
Oxidation of CaMKII determines the cardiotoxic effects of aldosterone.
Myocardial Infarction
Pharmacological inhibition of the mitochondrial NADPH oxidase 4/PKC?/Gal-3 pathway reduces left ventricular fibrosis following myocardial infarction.
Myocardial Infarction
Rac-1 as a new therapeutic target in cerebro- and cardio-vascular diseases.
Myocardial Infarction
Rac1 promotes the survival of H9c2 cells during serum deficiency targeting JNK/c-JUN/Cyclin-D1 and AKT2/MCL1 pathways.
Myocardial Infarction
Relationship between NADPH oxidase p22phox C242T, PARP-1 Val762Ala polymorphisms, angiographically verified coronary artery disease and myocardial infarction in South Indian patients with type 2 diabetes mellitus.
Myocardial Infarction
Suppression of oxidative stress in the endothelium and vascular wall.
Myocardial Ischemia
Effects of apocynin, an NADPH oxidase inhibitor, on levels of ADMA, MPO, iNOS and TLR4 induced by myocardial ischemia reperfusion.
Myocardial Ischemia
Role of NADPH oxidase and xanthine oxidase in mediating inducible VT/VF and triggered activity in a canine model of myocardial ischemia.
Myocardial Reperfusion Injury
Zinc pyrithione salvages reperfusion injury by inhibiting NADPH oxidase activation in cardiomyocytes.
Myocarditis
A P2X7 receptor antagonist attenuates experimental autoimmune myocarditis via suppressed myocardial CD4(+) T and macrophage infiltration and NADPH oxidase 2/4 expression in mice.
Myocarditis
NADPH oxidase inhibition ameliorates Trypanosoma cruzi-induced myocarditis during Chagas disease.
Myocarditis
Nox4-dependent ROS production is involved in CVB3-induced myocardial apoptosis.
nad(p)h oxidase (h2o2-forming) deficiency
A mutation located at the 5' splice junction sequence of intron 3 in the p67phox gene causes the lack of p67phox mRNA in a patient with chronic granulomatous disease.
nad(p)h oxidase (h2o2-forming) deficiency
Peroxynitrite-dependent activation of protein phosphatase type 2A mediates microvascular endothelial barrier dysfunction.
nad(p)h oxidase (h2o2-forming) deficiency
Sulfite stimulates NADPH oxidase of human neutrophils to produce active oxygen radicals via protein kinase C and Ca2+/calmodulin pathways.
nadph dehydrogenase (quinone) deficiency
Bacillus calmette-guerin infection in NADPH oxidase deficiency: defective mycobacterial sequestration and granuloma formation.
nadph dehydrogenase (quinone) deficiency
Cardiac oxidative stress and remodeling following infarction: role of NADPH oxidase.
nadph dehydrogenase (quinone) deficiency
Conventional versus interferon-gamma therapy in chronic granulomatous disease.
nadph dehydrogenase (quinone) deficiency
Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease.
nadph dehydrogenase (quinone) deficiency
Deficiency of nicotinamide adenine dinucleotide phosphate, reduced form oxidase enhances hepatocellular injury but attenuates fibrosis after chronic carbon tetrachloride administration.
nadph dehydrogenase (quinone) deficiency
Does NADPH oxidase deficiency cause artery dilatation in humans?
nadph dehydrogenase (quinone) deficiency
Earlier onset of neutrophil-mediated inflammation in the ultraviolet-exposed skin of mice deficient in myeloperoxidase and NADPH oxidase.
nadph dehydrogenase (quinone) deficiency
Genetic Phagocyte NADPH Oxidase Deficiency Enhances Nonviable Candida albicans-Induced Inflammation in Mouse Lungs.
nadph dehydrogenase (quinone) deficiency
Intractable colitis associated with chronic granulomatous disease in a young girl.
nadph dehydrogenase (quinone) deficiency
Low-density lipoprotein modification by normal, myeloperoxidase-deficient and NADPH oxidase-deficient granulocytes and the impact of redox active transition metal ions.
nadph dehydrogenase (quinone) deficiency
Molecular analysis of X-linked chronic granulomatous disease in five unrelated Korean patients.
nadph dehydrogenase (quinone) deficiency
Molecular quality control machinery contributes to the leukocyte NADPH oxidase deficiency in chronic granulomatous disease.
nadph dehydrogenase (quinone) deficiency
NADPH oxidase controls neutrophilic response to sterile inflammation in mice by regulating the IL-1?/G-CSF axis.
nadph dehydrogenase (quinone) deficiency
NADPH oxidase deficiency exacerbates angiotensin II-induced abdominal aortic aneurysms in mice.
nadph dehydrogenase (quinone) deficiency
NADPH oxidase deficiency in X-linked chronic granulomatous disease.
nadph dehydrogenase (quinone) deficiency
NADPH oxidase deficiency regulates Th lineage commitment and modulates autoimmunity.
nadph dehydrogenase (quinone) deficiency
NADPH oxidase deficiency results in reduced alveolar macrophage 5-lipoxygenase expression and decreased leukotriene synthesis.
nadph dehydrogenase (quinone) deficiency
NADPH oxidase deficiency underlies dysfunction of aged CD8+ Tregs.
nadph dehydrogenase (quinone) deficiency
NADPH oxidase deficient mice develop colitis and bacteremia upon infection with normally avirulent, TTSS-1- and TTSS-2-deficient Salmonella Typhimurium.
nadph dehydrogenase (quinone) deficiency
NADPH Oxidase Limits Collaborative Pattern-Recognition Receptor Signaling to Regulate Neutrophil Cytokine Production in Response to Fungal Pathogen-Associated Molecular Patterns.
nadph dehydrogenase (quinone) deficiency
NADPH oxidases regulate CD44 and hyaluronic acid expression in thrombin-treated vascular smooth muscle cells and in atherosclerosis.
nadph dehydrogenase (quinone) deficiency
Neutrophil-derived TNF drives fungal acute lung injury in chronic granulomatous disease.
nadph dehydrogenase (quinone) deficiency
NOX2 Deficiency Permits Sustained Survival of S. aureus in Macrophages and Contributes to Severity of Infection.
nadph dehydrogenase (quinone) deficiency
Nox2-containing NADPH oxidase deficiency confers protection from hindlimb ischemia in conditions of increased oxidative stress.
nadph dehydrogenase (quinone) deficiency
Oxidation of CaMKII determines the cardiotoxic effects of aldosterone.
nadph dehydrogenase (quinone) deficiency
P47(phox)-deficient NADPH oxidase defect in neutrophils of diabetic mouse strains, C57BL/6J-m db/db and db/+.
nadph dehydrogenase (quinone) deficiency
Potency of antileukoprotease and alpha 1-antitrypsin to inhibit degradation of fibrinogen by adherent polymorphonuclear leukocytes from normal subjects and patients with chronic granulomatous disease.
nadph dehydrogenase (quinone) deficiency
Respiratory control in neonatal mice with NADPH oxidase deficiency.
nadph dehydrogenase (quinone) deficiency
Severe glucose-6-phosphate dehydrogenase deficiency leads to susceptibility to infection and absent NETosis.
nadph dehydrogenase (quinone) deficiency
The three CYBA variants (rs4673, rs1049254 and rs1049255) are benign: new evidence from a patient with CGD.
nadph dehydrogenase (quinone) deficiency
[Contribution of neutrophils to Aspergillus infection]
Nasal Polyps
Expression of nicotinamide adenine dinucleotide phosphate oxidase in chronic rhinosinusitis with nasal polyps.
Nasal Polyps
Overexpression of the superoxide anion and NADPH oxidase isoforms 1 and 4 (NOX1 and NOX4) in allergic nasal mucosa.
Neoplasm Metastasis
Adenosine A(3) receptor suppresses prostate cancer metastasis by inhibiting NADPH oxidase activity.
Neoplasm Metastasis
Expression of NOX Family Genes and Their Clinical Significance in Colorectal Cancer.
Neoplasm Metastasis
Inhibition of NADPH oxidase protects against metastasis of human lung cancer by decreasing microRNA-21.
Neoplasm Metastasis
Modulation of Nqo1 activity intercepts anoikis resistance and reduces metastatic potential of hepatocellular carcinoma.
Neoplasm Metastasis
NADPH oxidase 1-dependent ROS is crucial for TLR4 signaling to promote tumor metastasis of non-small cell lung cancer.
Neoplasm Metastasis
Suppression of NADPH Oxidase Activity May Slow the Expansion of Osteolytic Bone Metastases.
Neoplasms
(-)-Epicatechin protects the intestinal barrier from high fat diet-induced permeabilization: Implications for steatosis and insulin resistance.
Neoplasms
(-)-Epicatechin Reduces Blood Pressure and Improves Left Ventricular Function and Compliance in Deoxycorticosterone Acetate-Salt Hypertensive Rats.
Neoplasms
17beta-estradiol inhibits NADPH oxidase activity through the regulation of p47phox mRNA and protein expression in THP-1 cells.
Neoplasms
4-fluoro-2-methoxyphenol, an apocynin analog with enhanced inhibitory effect on leukocyte oxidant production and phagocytosis.
Neoplasms
A nonpolar blueberry fraction blunts NADPH oxidase activation in neuronal cells exposed to tumor necrosis factor-?.
Neoplasms
Ability of okadaic acid and other protein phosphatase inhibitors to mimic the stimulatory effects of 12-O-tetradecanoylphorbol-13-acetate on hydroperoxide production in mouse epidermis in vivo.
Neoplasms
Acetylcholinesterase inhibitors attenuate atherogenesis in apolipoprotein E-knockout mice.
Neoplasms
Activated glycine receptors may decrease endosomal NADPH oxidase activity by opposing ClC-3-mediated efflux of chloride from endosomes.
Neoplasms
Activation of metabotropic glutamate receptor 5 improves recovery after spinal cord injury in rodents.
Neoplasms
Activation of primary human monocytes by the oxidized form of alpha1-antitrypsin.
Neoplasms
Activation of the respiratory burst enzyme from human neutrophils in a cell-free system. Evidence for a soluble cofactor.
Neoplasms
Activation of TLR4 is required for the synergistic induction of dual oxidase 2 and dual oxidase A2 by IFN-? and lipopolysaccharide in human pancreatic cancer cell lines.
Neoplasms
Acute tumor necrosis factor alpha signaling via NADPH oxidase in microvascular endothelial cells: role of p47phox phosphorylation and binding to TRAF4.
Neoplasms
Adenosine A(3) receptor suppresses prostate cancer metastasis by inhibiting NADPH oxidase activity.
Neoplasms
Angiotensin Type 1 Receptor Antagonists Protect Against Alpha-Synuclein-Induced Neuroinflammation and Dopaminergic Neuron Death.
Neoplasms
Annexin peptide Ac2-26 suppresses TNF?-induced inflammatory responses via inhibition of Rac1-dependent NADPH oxidase in human endothelial cells.
Neoplasms
Anti-inflammatory and anti-infectious effects of Evodia rutaecarpa (Wuzhuyu) and its major bioactive components.
Neoplasms
Anti-inflammatory effect of interleukin-10 on human neutrophil respiratory burst involves inhibition of GM-CSF-induced p47PHOX phosphorylation through a decrease in ERK1/2 activity.
Neoplasms
Anti-inflammatory effects of dimemorfan on inflammatory cells and LPS-induced endotoxin shock in mice.
Neoplasms
Antiangiogenic action of redox-modulating Mn(III) meso-tetrakis(N-ethylpyridinium-2-yl)porphyrin, MnTE-2-PyP(5+), via suppression of oxidative stress in a mouse model of breast tumor.
Neoplasms
Association of CYBA gene (-930 A/G and 242 C/T) polymorphisms with oxidative stress in breast cancer: a case-control study.
Neoplasms
Attenuation of aortic injury by ursolic acid through RAGE-Nox-NF?B pathway in streptozocin-induced diabetic rats.
Neoplasms
Attenuation of oxidative stress and cardiac dysfunction by bisoprolol in an animal model of dilated cardiomyopathy.
Neoplasms
beta-amyloid activates the O-2 forming NADPH oxidase in microglia, monocytes, and neutrophils. A possible inflammatory mechanism of neuronal damage in Alzheimer's disease.
Neoplasms
Binding of pleomorphic adenoma gene-like 2 to the tumor necrosis factor (TNF)-alpha-responsive region of the NCF2 promoter regulates p67(phox) expression and NADPH oxidase activity.
Neoplasms
Carbon ion beams induce hepatoma cell death by NADPH oxidase-mediated mitochondrial damage.
Neoplasms
CD40 induces renal cell carcinoma-specific differential regulation of TRAF proteins, ASK1 activation and JNK/p38-mediated, ROS-dependent mitochondrial apoptosis.
Neoplasms
Cellular crosstalk between TNF-?, NADPH oxidase, PKC?2, and C2GNT in human leukocytes.
Neoplasms
Co-morbidity and systemic inflammation as drivers of cognitive decline: new experimental models adopting a broader paradigm in dementia research.
Neoplasms
Cross talk between mitochondria and superoxide generating NADPH oxidase in breast and ovarian tumors.
Neoplasms
Cytokine activation of nuclear factor kappa B in vascular smooth muscle cells requires signaling endosomes containing Nox1 and ClC-3.
Neoplasms
d-Limonene protects PC12 cells against corticosterone-induced neurotoxicity by activating the AMPK pathway.
Neoplasms
Death receptors 4 and 5 activate Nox1 NADPH oxidase through riboflavin kinase to induce reactive oxygen species-mediated apoptotic cell death.
Neoplasms
Deletion of angiotensin-converting enzyme 2 exacerbates renal inflammation and injury in apolipoprotein E-deficient mice through modulation of the nephrin and TNF-alpha-TNFRSF1A signaling.
Neoplasms
Demonstration of reversible priming of human neutrophils using platelet-activating factor.
Neoplasms
Dendritic Cells but Not Macrophages Sense Tumor Mitochondrial DNA for Cross-priming through Signal Regulatory Protein ? Signaling.
Neoplasms
Development of a PET radiotracer for non-invasive imaging of the reactive oxygen species, superoxide, in vivo.
Neoplasms
Differential Effects of CORM-2 and CORM-401 in Murine Intestinal Epithelial MODE-K Cells under Oxidative Stress.
Neoplasms
Differential sensitivity of the tyrosyl radical of mouse ribonucleotide reductase to nitric oxide and peroxynitrite.
Neoplasms
Differential upregulation of Nox homologues of NADPH oxidase by tumor necrosis factor-alpha in human aortic smooth muscle and embryonic kidney cells.
Neoplasms
Diphenyleneiodonium sulfate, an NADPH oxidase inhibitor, prevents early alcohol-induced liver injury in the rat.
Neoplasms
Dual Oxidase2 and pancreatic adenocarcinoma: IFN-?-mediated dual oxidase2 overexpression results in H2O2-induced, ERKassociated up-regulation of HIF-1? and VEGF-A.
Neoplasms
Effects of thermal manipulation of eggs on the response of jejunal mucosae to posthatch chronic heat stress in broiler chickens.
Neoplasms
Endothelin type B receptor promotes cofilin rod formation and dendritic loss in neurons by inducing oxidative stress and cofilin activation.
Neoplasms
Enhancement of innate immunity against Mycobacterium avium infection by immunostimulatory DNA is mediated by indoleamine 2,3-dioxygenase.
Neoplasms
Escitalopram Ameliorates Cognitive Impairment in D-Galactose-Injected Ovariectomized Rats: Modulation of JNK, GSK-3?, and ERK Signalling Pathways.
Neoplasms
Essential role of the NADPH oxidase subunit p47(phox) in endothelial cell superoxide production in response to phorbol ester and tumor necrosis factor-alpha.
Neoplasms
Ethanol metabolism by a transplantable hepatocellular carcinoma. Role of microsomes and mitochondria.
Neoplasms
Exacerbation of albuminuria and renal fibrosis in subtotal renal ablation model of adiponectin-knockout mice.
Neoplasms
Exploring the protective role of apocynin, a specific NADPH oxidase inhibitor, in cisplatin-induced cardiotoxicity in rats.
Neoplasms
Expression of NADPH oxidase homologues and accessory genes in human cancer cell lines, tumours and adjacent normal tissues.
Neoplasms
Expression of NOX Family Genes and Their Clinical Significance in Colorectal Cancer.
Neoplasms
Extracellular matrix stimulates reactive oxygen species production and increases pancreatic cancer cell survival through 5-lipoxygenase and NADPH oxidase.
Neoplasms
Gene Polymorphism of Xenobiotic Biotransformation Enzymes in Patients with Classical Ph-Negative Myeloproliferative Neoplasms.
Neoplasms
Hace1 controls ROS generation of vertebrate Rac1-dependent NADPH oxidase complexes.
Neoplasms
Histamine promotes the development of monocyte-derived dendritic cells and reduces tumor growth by targeting the myeloid NADPH oxidase.
Neoplasms
Hypoxia promotes the metastasis of pancreatic cancer through regulating NOX4/KDM5A-mediated histone methylation modification changes in a HIF1A-independent manner.
Neoplasms
Hypoxia-Induced Signaling Promotes Prostate Cancer Progression: Exosomes Role as Messenger of Hypoxic Response in Tumor Microenvironment.
Neoplasms
Imaging neutrophil activation: analysis of the translocation and utilization of NAD(P)H-associated autofluorescence during antibody-dependent target oxidation.
Neoplasms
Imaging the Impact of Nox4 in Cycling Hypoxia-mediated U87 Glioblastoma Invasion and Infiltration.
Neoplasms
Impact of Physical Activity on Oxidative Stress Markers in Patients with Metastatic Breast Cancer.
Neoplasms
Increasing Superoxide Production and the Labile Iron Pool in Tumor Cells may Sensitize Them to Extracellular Ascorbate.
Neoplasms
Induction of hepatoma carcinoma cell apoptosis through activation of the JNK-nicotinamide adenine dinucleotide phosphate (NADPH) oxidase-ROS self-driven death signal circuit.
Neoplasms
Inhibition of NADPH oxidase protects against metastasis of human lung cancer by decreasing microRNA-21.
Neoplasms
Inhibition of nuclear factor erythroid 2-related factor 2 exacerbates HIV-1 gp120-induced oxidative and inflammatory response: role in HIV associated neurocognitive disorder.
Neoplasms
Inhibition of Protein Kinase C ?(2) Prevents Tumor Necrosis Factor-?-Induced Apoptosis and Oxidative Stress in Endothelial Cells: The Role of NADPH Oxidase Subunits.
Neoplasms
Insulin mediated DNA damage in mammalian colon cells and human lymphocytes in vitro.
Neoplasms
Intracellular expression of ROS-generating NADPH oxidase NOX4 in normal and cancer thyroid tissues.
Neoplasms
Involvement of Rho-kinase/I?B-?/NF-?B activation in IL-1?-induced inflammatory response and oxidative stress in human chondrocytes.
Neoplasms
Khz (fusion of Ganoderma lucidum and Polyporus umbellatus mycelia) induces apoptosis by increasing intracellular calcium levels and activating JNK and NADPH oxidase-dependent generation of reactive oxygen species.
Neoplasms
Loss of NADPH quinone oxidoreductase in the prostate and enhanced serum levels of cytokine-induced neutrophil chemoattractant 2alpha in hormone-stimulated noble rats: potential role in prostatic intraepithelial neoplasia development.
Neoplasms
Magnolia officinalis Reverses Alcoholic Fatty Liver by Inhibiting the Maturation of Sterol Regulatory Element-Binding Protein-1c.
Neoplasms
Metastatic breast carcinoma induces vascular endothelial dysfunction in Balb-c mice: Role of the tumor necrosis factor-? and NADPH oxidase.
Neoplasms
MicroRNA Targeting Nicotinamide Adenine Dinucleotide Phosphate Oxidases in Cancer.
Neoplasms
Minimizing the cancer-promotional activity of cox-2 as a central strategy in cancer prevention.
Neoplasms
Modulation of myocardial injury and collagen deposition following ischaemia-reperfusion by linagliptin and liraglutide, and both together.
Neoplasms
Modulation of Nqo1 activity intercepts anoikis resistance and reduces metastatic potential of hepatocellular carcinoma.
Neoplasms
Modulation of reactive oxygen species in skeletal muscle by myostatin is mediated through NF-?B.
Neoplasms
Molecular mechanisms of felodipine suppressing atherosclerosis in high-cholesterol-diet apolipoprotein e-knockout mice.
Neoplasms
Molecular mechanisms of irbesartan suppressing atherosclerosis in high cholesterol-diet apolipoprotein E knock-out mice.
Neoplasms
Muscle dysfunction associated with adjuvant-induced arthritis is prevented by antioxidant treatment.
Neoplasms
Myeloid GRK2 Regulates Obesity-Induced Endothelial Dysfunction by Modulating Inflammatory Responses in Perivascular Adipose Tissue.
Neoplasms
Myeloid-derived suppressor cells modulate immune responses independently of NADPH oxidase in the ovarian tumor microenvironment in mice.
Neoplasms
N-Adamantyl-4-Methylthiazol-2-Amine Attenuates Glutamate-Induced Oxidative Stress and Inflammation in the Brain.
Neoplasms
NADPH accumulation is responsible for apoptosis in breast cancer cells induced by fatty acid synthase inhibition.
Neoplasms
NADPH oxidase 1-dependent ROS is crucial for TLR4 signaling to promote tumor metastasis of non-small cell lung cancer.
Neoplasms
NADPH Oxidase Activation Contributes to Heavy Ion Irradiation-Induced Cell Death.
Neoplasms
NADPH oxidase and uncoupled nitric oxide synthase are major sources of reactive oxygen species in oral squamous cell carcinoma. Potential implications for immune regulation in high oxidative stress conditions.
Neoplasms
NADPH Oxidase as a Target for Modulation of Radiation Response; Implications to Carcinogenesis and Radiotherapy.
Neoplasms
NADPH oxidase biology and the regulation of tyrosine kinase receptor signaling and cancer drug cytotoxicity.
Neoplasms
NADPH oxidase contributes to vascular inflammation, insulin resistance, and remodeling in the transgenic (mRen2) rat.
Neoplasms
NADPH oxidase drives cytokine and neurotoxin release from microglia and macrophages in response to HIV-Tat.
Neoplasms
NADPH oxidase DUOX1 and DUOX2 but not NOX4 are independent predictors in hepatocellular carcinoma after hepatectomy.
Neoplasms
NADPH oxidase NOX1 controls autocrine growth of liver tumor cells through up-regulation of the epidermal growth factor receptor pathway.
Neoplasms
NADPH Oxidase NOX4 Is a Critical Mediator of BRAF(V600E)-Induced Downregulation of the Sodium/Iodide Symporter in Papillary Thyroid Carcinomas.
Neoplasms
NADPH oxidase overexpression in human colon cancers and rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
Neoplasms
NADPH oxidase priming and p47phox phosphorylation in neutrophils from synovial fluid of patients with rheumatoid arthritis and spondylarthropathy.
Neoplasms
NADPH oxidase subunit 4 mediates cycling hypoxia-promoted radiation resistance in glioblastoma multiforme.
Neoplasms
NADPH oxidase subunit 4-mediated reactive oxygen species contribute to cycling hypoxia-promoted tumor progression in glioblastoma multiforme.
Neoplasms
NADPH oxidase subunit p22(phox)-mediated reactive oxygen species contribute to angiogenesis and tumor growth through AKT and ERK1/2 signaling pathways in prostate cancer.
Neoplasms
NADPH OXIDASES AS REGULATORS OF TUMOR ANGIOGENESIS: CURRENT AND EMERGING CONCEPTS.
Neoplasms
Nitroglycerine-induced nitrate tolerance compromises propofol protection of the endothelial cells against TNF-?: the role of PKC-?2 and NADPH oxidase.
Neoplasms
NO modulates NADPH oxidase function via heme oxygenase-1 in human endothelial cells.
Neoplasms
Nox2 and Nox4 mediate tumor necrosis factor-alpha-induced ventricular remodeling in mice.
Neoplasms
NOX5-L can stimulate proliferation and apoptosis depending on its levels and cellular context, determining cancer cell susceptibility to cisplatin.
Neoplasms
Overactivation of the MEK/ERK pathway in liver tumor cells confers resistance to TGF-{beta}-induced cell death through impairing up-regulation of the NADPH oxidase NOX4.
Neoplasms
Paeonol attenuates advanced oxidation protein product-induced oxidative stress injury in THP-1 macrophages.
Neoplasms
Panaxydol induces apoptosis through an increased intracellular calcium level, activation of JNK and p38 MAPK and NADPH oxidase-dependent generation of reactive oxygen species.
Neoplasms
Paradoxical role of the NADPH oxidase NOX4 in early preneoplastic stages of hepatocytes induced by amino acid deprivation.
Neoplasms
Pathogenic Effects of IFIT2 and Interferon-? during Fatal Systemic Candida albicans Infection.
Neoplasms
Pattern of expression of immune-relevant genes in the gonad of a teleost, the gilthead seabream (Sparus aurata L.).
Neoplasms
Phytochemical Inhibition of Multidrug Resistance Protein-1 as a Therapeutic Strategy for Hemangioendothelioma.
Neoplasms
Pituitary adenylate cyclase-activating polypeptide (PACAP) 38 and PACAP4-6 are neuroprotective through inhibition of NADPH oxidase: potent regulators of microglia-mediated oxidative stress.
Neoplasms
PKC? activation mediates angiogenesis via NADPH oxidase activity in PC-3 prostate cancer cells.
Neoplasms
PKCzeta regulates TNF-alpha-induced activation of NADPH oxidase in endothelial cells.
Neoplasms
Priming of NADPH oxidase by tumor necrosis factor alpha in patients with inflammatory and autoimmune rheumatic diseases.
Neoplasms
Protective effects of apocynin nitrone on acute lung injury induced by lipopolysaccharide in rats.
Neoplasms
Raised neutrophil phospholipase A2 activity and defective priming of NADPH oxidase and phospholipase A2 in sickle cell disease.
Neoplasms
Reactive oxygen species and angiogenesis: NADPH oxidase as target for cancer therapy.
Neoplasms
Reconstituted high-density lipoprotein suppresses leukocyte NADPH oxidase activation by disrupting lipid rafts.
Neoplasms
Reduced NADPH oxidase type 2 activity mediates sleep fragmentation-induced effects on TC1 tumors in mice.
Neoplasms
Reduced Plasma Kallistatin Is Associated With the Severity of Coronary Artery Disease, and Kallistatin Treatment Attenuates Atherosclerotic Plaque Formation in Mice.
Neoplasms
Regression of Diffuse B-cell Lymphoma of the Leg with Intralesional Gentian Violet.
Neoplasms
Renoprotective Effects of Alpha Lipoic Acid on Iron Overload-Induced Kidney Injury in Rats by Suppressing NADPH Oxidase 4 and p38 MAPK Signaling.
Neoplasms
RNAi-mediated silencing of NOX4 inhibited the invasion of gastric cancer cells through JAK2/STAT3 signaling.
Neoplasms
Role of neutrophil NADPH oxidase in the mechanism of tumor necrosis factor-alpha -induced NF-kappa B activation and intercellular adhesion molecule-1 expression in endothelial cells.
Neoplasms
Role of nitric oxide in downregulation of cytochrome P450 1a1 and NADPH: Quinone oxidoreductase 1 by tumor necrosis factor-alpha and lipopolysaccharide.
Neoplasms
ROS generation via NOX4 and its utility in the cytological diagnosis of urothelial carcinoma of the urinary bladder.
Neoplasms
ROS mediates interferon gamma induced phosphorylation of Src, through the Raf/ERK pathway, in MCF-7 human breast cancer cell line.
Neoplasms
Selective killing of cancer cells harboring mutant RAS by concomitant inhibition of NADPH oxidase and glutathione biosynthesis.
Neoplasms
Selective recapitulation of conserved and nonconserved regions of putative NOXA1 protein activation domain confers isoform-specific inhibition of Nox1 oxidase and attenuation of endothelial cell migration.
Neoplasms
Signaling at the Crossroads: Matrix-Derived Proteoglycan and Reactive Oxygen Species Signaling.
Neoplasms
STAT5A-mediated NOX5-L expression promotes the proliferation and metastasis of breast cancer cells.
Neoplasms
Subclinical inflammation/oxidation as revealed by altered gene expression profiles in subjects with impaired glucose tolerance and Type 2 diabetes patients.
Neoplasms
Sulforaphane alleviates hepatic ischemia-reperfusion injury through promoting the activation of Nrf-2/HO-1 signaling.
Neoplasms
Superoxide production and NADPH oxidase expression in human rheumatoid synovial cells: regulation by interleukin-1beta and tumour necrosis factor-alpha.
Neoplasms
Suppression of NADPH Oxidase Activity May Slow the Expansion of Osteolytic Bone Metastases.
Neoplasms
Targeting Inflammatory Processes Mediated by TRPVI and TNF-? for Treating Noise-Induced Hearing Loss.
Neoplasms
Targeting the Warburg effect in cancer cells through ENO1 knockdown rescues oxidative phosphorylation and induces growth arrest.
Neoplasms
Targeting Tyrosine Kinase Inhibitor-Resistant Non-Small Cell Lung Cancer by Inducing Epidermal Growth Factor Receptor Degradation via Methionine 790 Oxidation.
Neoplasms
The effect of IFN-gamma and TNF-alpha on the eosinophilic differentiation and NADPH oxidase activation of human HL-60 clone 15 cells.
Neoplasms
The effect of IFN-gamma and TNF-alpha on the NADPH oxidase system of human colostrum macrophages, blood monocytes, and THP-1 cells.
Neoplasms
The Human NADPH Oxidase, Nox4, Regulates Cytoskeletal Organization in Two Cancer Cell Lines, HepG2 and SH-SY5Y.
Neoplasms
The interplay of reactive oxygen species and the epidermal growth factor receptor in tumor progression and drug resistance.
Neoplasms
The NADPH oxidase 4 is a major source of hydrogen peroxide in human granulosa-lutein and granulosa tumor cells.
Neoplasms
The NADPH oxidase inhibitor VAS2870 impairs cell growth and enhances TGF-?-induced apoptosis of liver tumor cells.
Neoplasms
The NADPH oxidase NOX4 represses epithelial to amoeboid transition and efficient tumour dissemination.
Neoplasms
The NADPH oxidase of human polymorphonuclear leukocytes. Evidence for regulation by multiple signals.
Neoplasms
The NADPH oxidase subunit p22phox inhibits the function of the tumor suppressor protein tuberin.
Neoplasms
The prolyl isomerase Pin1 acts as a novel molecular switch for TNF{alpha}-induced priming of the NADPH oxidase in human neutrophils.
Neoplasms
The Role of Acrolein and NADPH Oxidase in the Granulocyte-Mediated Growth-Inhibition of Tumor Cells.
Neoplasms
Thymidine catabolism promotes NADPH oxidase-derived reactive oxygen species (ROS) signalling in KB and yumoto cells.
Neoplasms
Tiron protects against nicotine-induced lung and liver injury through antioxidant and anti-inflammatory actions in rats in vivo.
Neoplasms
TNF-?/TNFR1 signaling promotes gastric tumorigenesis through induction of Noxo1 and Gna14 in tumor cells.
Neoplasms
Transcriptional regulation of NOX genes express ion in human breast adenocarcinoma MCF-7 cells is modulated by adaptor protein Ruk/CIN 85.
Neoplasms
Transient receptor potential ankyrin 1 (TRPA1) plays a critical role in a mouse model of cancer pain.
Neoplasms
Treadmill exercise produces neuroprotective effects in a murine model of Parkinson's disease by regulating the TLR2/MyD88/NF-?B signaling pathway.
Neoplasms
Tuberin regulates reactive oxygen species in renal proximal cells, kidney from rodents, and kidney from patients with tuberous sclerosis complex.
Neoplasms
Tumor necrosis factor alpha activates transcription of the NADPH oxidase organizer 1 (NOXO1) gene and upregulates superoxide production in colon epithelial cells.
Neoplasms
Tumor necrosis factor and immune interferon synergistically induce cytochrome b-245 heavy-chain gene expression and nicotinamide-adenine dinucleotide phosphate hydrogenase oxidase in human leukemic myeloid cells.
Neoplasms
Tumor necrosis factor triggers redistribution to a Triton X-100-insoluble, cytoskeletal fraction of beta 2 integrins, NADPH oxidase components, tyrosine phosphorylated proteins, and the protein tyrosine kinase p58fgr in human neutrophils adherent to fibrinogen.
Neoplasms
Tumor necrosis factor-?-induced nuclear factor-kappaB activation in human cardiomyocytes is mediated by NADPH oxidase.
Neoplasms
Tumor necrosis factor-alpha: a possible priming agent for the polymorphonuclear leukocyte-reduced nicotinamide-adenine dinucleotide phosphate oxidase in hypertension.
Neoplasms
Tumor promoter TPA stimulates MMP-9 secretion from human keratinocytes by activation of superoxide-producing NADPH oxidase.
Neoplasms
Tumor-associated macrophages favor C26 murine colon carcinoma cell proliferation in an oxidative stress-dependent manner.
Neoplasms
Understanding the biology of reactive oxygen species and their link to cancer: NADPH oxidases as novel pharmacological targets.
Neoplasms
Upregulation of the NADPH oxidase NOX4 by TGF-beta in hepatocytes is required for its pro-apoptotic activity.
Neoplasms
Vaccarin alleviates hypertension and nephropathy in renovascular hypertensive rats.
Neoplasms
[Dynamic analysis of modification of peripheral neutrophils functional activity and its regulation during tumor growth in vivo]
Neoplasms
[Effect of Porphyromonas gingivalis infection on atherosclerosis in apolipoprotein-E knockout mice].
Nephrolithiasis
Effects of apocynin and losartan treatment on renal oxidative stress in a rat model of calcium oxalate nephrolithiasis.
Nephrolithiasis
Role of mitochondria and NADPH oxidase derived reactive oxygen species in hyperoxaluria induced nephrolithiasis: therapeutic intervention with combinatorial therapy of N-acetyl cysteine and Apocynin.
Nephrolithiasis
The selective NADPH oxidase inhibitor apocynin has potential prophylactic effects on melamine-related nephrolithiasis in vitro and in vivo.
Nephrosis
NADPH oxidase-derived ROS contributes to upregulation of TRPC6 expression in puromycin aminonucleoside-induced podocyte injury.
Nervous System Diseases
Testosterone induces neuroprotection from oxidative stress. Effects on catalase activity and 3-nitro-L-tyrosine incorporation into alpha-tubulin in a mouse neuroblastoma cell line.
Nervous System Diseases
The Role of NADPH Oxidase in Neuronal Death and Neurogenesis after Acute Neurological Disorders.
Neuralgia
A3 adenosine receptor agonist prevents the development of paclitaxel-induced neuropathic pain by modulating spinal glial-restricted redox-dependent signaling pathways.
Neuralgia
Inhibition of NOX2 signaling limits pain-related behavior and improves motor function in male mice after spinal cord injury: Participation of IL-10/miR-155 pathways.
Neuralgia
NADPH oxidase 2-derived reactive oxygen species in spinal cord microglia contribute to peripheral nerve injury-induced neuropathic pain.
Neuralgia
Neuroinflammation, oxidative stress and their interplay in neuropathic pain: Focus on specialized pro-resolving mediators and NADPH oxidase inhibitors as potential therapeutic strategies.
Neuralgia
Nociceptive behavior induced by chemotherapeutic paclitaxel and beneficial role of antioxidative pathways.
Neuralgia
Treatment with NADPH oxidase inhibitor apocynin alleviates diabetic neuropathic pain in rats.
Neuroblastoma
A key role for the microglial NADPH oxidase in APP-dependent killing of neurons.
Neuroblastoma
Angiotensin II Induces Differentiation of Human Neuroblastoma Cells by Increasing MAP2 and ROS Levels.
Neuroblastoma
Ceramide kinase regulates TNF?-stimulated NADPH oxidase activity and eicosanoid biosynthesis in neuroblastoma cells.
Neuroblastoma
Evidences of plasma membrane-mediated ROS generation upon ELF exposure in neuroblastoma cells supported by a computational multiscale approach.
Neuroblastoma
HaRas activates the NADPH oxidase complex in human neuroblastoma cells via extracellular signal-regulated kinase 1/2 pathway.
Neuroblastoma
Interferon-? counter-regulates its own pro-apoptotic action by activating p38 MAPK signalling in human SH-SY5Y neuroblastoma cells.
Neuroblastoma
NADPH oxidase mediates the oxygen-glucose deprivation/reperfusion-induced increase in the tyrosine phosphorylation of the N-methyl-D-aspartate receptor NR2A subunit in retinoic acid differentiated SH-SY5Y Cells.
Neuroblastoma
PKC delta and NADPH oxidase in retinoic acid-induced neuroblastoma cell differentiation.
Neuroblastoma
Rac1-NADPH oxidase-regulated generation of reactive oxygen species mediates glutamate-induced apoptosis in SH-SY5Y human neuroblastoma cells.
Neuroblastoma
Reactive oxygen species regulate the levels of dual oxidase (Duox1-2) in human neuroblastoma cells.
Neuroblastoma
Role of NADPH oxidase in MAPK signaling activation by a 50 Hz magnetic field in human neuroblastoma cells.
Neuroblastoma
Rotenone induces neurotoxicity through Rac1-dependent activation of NADPH oxidase in SHSY-5Y cells.
Neurodegenerative Diseases
AGEs Induce Cell Death via Oxidative and Endoplasmic Reticulum Stresses in Both Human SH-SY5Y Neuroblastoma Cells and Rat Cortical Neurons.
Neurodegenerative Diseases
Critical role of the Mac1/NOX2 pathway in mediating reactive microgliosis-generated chronic neuroinflammation and progressive neurodegeneration.
Neurodegenerative Diseases
NADPH oxidase produces reactive oxygen species and maintains survival of rat astrocytes.
Neurodegenerative Diseases
NADPH oxidases: novel therapeutic targets for neurodegenerative diseases.
Neurodegenerative Diseases
Neurodegenerative Disease: Roles for Sex, Hormones, and Oxidative Stress.
Neurodegenerative Diseases
Neuroprotection by glucose-6-phosphate dehydrogenase and the pentose phosphate pathway.
Neurodegenerative Diseases
NOX1/NADPH oxidase negatively regulates nerve growth factor-induced neurite outgrowth.
Neurodegenerative Diseases
Phospholipases A2 and neural membrane dynamics: implications for Alzheimer's disease.
Neurodegenerative Diseases
Rotenone induces neurotoxicity through Rac1-dependent activation of NADPH oxidase in SHSY-5Y cells.
Neurodegenerative Diseases
Subpicomolar diphenyleneiodonium inhibits microglial NADPH oxidase with high specificity and shows great potential as a therapeutic agent for neurodegenerative diseases.
Neurodegenerative Diseases
The roles of NADPH oxidase and phospholipases A2 in oxidative and inflammatory responses in neurodegenerative diseases.
Neurodegenerative Diseases
Thioxanthenes, chlorprothixene and flupentixol inhibit proton currents in BV2 microglial cells.
Neurogenic Inflammation
Combination of Wu Lin San and Shan Zha ameliorates substance P-induced hyperactive bladder via the inhibition of neutrophil NADPH oxidase activity.
Neuroinflammatory Diseases
Analyzing Nicotinamide Adenine Dinucleotide Phosphate Oxidase Activation in Aging and Vascular Amyloid Pathology.
Neuroinflammatory Diseases
Angiotensin II-triggered kinase signaling cascade in the central nervous system.
Neuroinflammatory Diseases
Apocynin prevents mitochondrial burdens, microglial activation, and pro-apoptosis induced by a toxic dose of methamphetamine in the striatum of mice via inhibition of p47phox activation by ERK.
Neuroinflammatory Diseases
Aspirin-triggered lipoxin A? attenuates lipopolysaccharide-induced intracellular ROS in BV2 microglia cells by inhibiting the function of NADPH oxidase.
Neuroinflammatory Diseases
Astragaloside IV ameliorates cognitive impairment and neuroinflammation in an oligomeric A? induced Alzheimer's disease mouse model via inhibition of microglial activation and NADPH oxidase expression.
Neuroinflammatory Diseases
Complement receptor 3 mediates NADPH oxidase activation and dopaminergic neurodegeneration through a Src-Erk-dependent pathway.
Neuroinflammatory Diseases
Critical role of the Mac1/NOX2 pathway in mediating reactive microgliosis-generated chronic neuroinflammation and progressive neurodegeneration.
Neuroinflammatory Diseases
Design of dual inhibitors of ROCK-I and NOX2 as potential leads for the treatment of neuroinflammation associated with various neurological diseases including autism spectrum disorder.
Neuroinflammatory Diseases
Developmental onset of bilirubin-induced neurotoxicity involves Toll-like receptor 2-dependent signaling in humanized UDP-glucuronosyltransferase1 mice.
Neuroinflammatory Diseases
Effect of the NADPH oxidase inhibitor apocynin on ischemia-reperfusion hippocampus injury in rat brain.
Neuroinflammatory Diseases
Inhibition of NADPH oxidase by apocynin prevents learning and memory deficits in a mouse Parkinson's disease model.
Neuroinflammatory Diseases
Inhibition of NADPH oxidase promotes alternative and anti-inflammatory microglial activation during neuroinflammation.
Neuroinflammatory Diseases
Inhibitory effects of antihistamines, diphenhydramine and chlorpheniramine, on proton currents in BV2 microglial cells.
Neuroinflammatory Diseases
Locus coeruleus neurons are most sensitive to chronic neuroinflammation-induced neurodegeneration.
Neuroinflammatory Diseases
NADPH oxidase regulates paraquat and maneb-induced dopaminergic neurodegeneration through ferroptosis.
Neuroinflammatory Diseases
Neuroinflammation, oxidative stress and their interplay in neuropathic pain: Focus on specialized pro-resolving mediators and NADPH oxidase inhibitors as potential therapeutic strategies.
Neuroinflammatory Diseases
Neuroinflammation: modulation by flavonoids and mechanisms of action.
Neuroinflammatory Diseases
Neuroprotective Benefits of Exercise and MitoQ on Memory Function, Mitochondrial Dynamics, Oxidative Stress, and Neuroinflammation in D-Galactose-Induced Aging Rats.
Neuroinflammatory Diseases
Oxidative Stress, Neuroinflammation, and NADPH Oxidase: Implications in the Pathogenesis and Treatment of Alzheimer's Disease.
Neuroinflammatory Diseases
Progressive neurodegeneration after experimental brain trauma: association with chronic microglial activation.
Neuroinflammatory Diseases
Resveratrol inhibits oligomeric A?-induced microglial activation via NADPH oxidase.
Neuroinflammatory Diseases
Subpicomolar diphenyleneiodonium inhibits microglial NADPH oxidase with high specificity and shows great potential as a therapeutic agent for neurodegenerative diseases.
Neuroinflammatory Diseases
Targeting neuroinflammation to treat cerebral ischemia - The role of TIGAR/NADPH axis.
Neuroinflammatory Diseases
Teriflunomide Does Not Change Dynamics of Nadph Oxidase Activation and Neuronal Dysfunction During Neuroinflammation.
Neuroinflammatory Diseases
The role of Nox2-derived ROS in the development of cognitive impairment after sepsis.
Neutropenia
Beta-glucan is a fungal determinant for adhesion-dependent human neutrophil functions.
Neutropenia
Human polymorphonuclear leukocytes inhibit Aspergillus fumigatus conidial growth by lactoferrin-mediated iron depletion.
Non-alcoholic Fatty Liver Disease
Association between the CYBA and NOX4 genes of NADPH oxidase and its relationship with metabolic syndrome in non-alcoholic fatty liver disease in Brazilian population.
Non-alcoholic Fatty Liver Disease
HMGB1-RAGE pathway drives peroxynitrite signaling-induced IBD-like inflammation in murine nonalcoholic fatty liver disease.
Non-alcoholic Fatty Liver Disease
Micro-RNA 21 inhibition of SMAD7 enhances fibrogenesis via leptin-mediated NADPH oxidase in experimental and human nonalcoholic steatohepatitis.
Non-alcoholic Fatty Liver Disease
NADPH Oxidase-Derived Peroxynitrite Drives Inflammation in Mice and Human Nonalcoholic Steatohepatitis via TLR4-Lipid Raft Recruitment.
Non-alcoholic Fatty Liver Disease
Role of oxidative stress in the pathogenesis of nonalcoholic fatty liver disease.
Non-alcoholic Fatty Liver Disease
The NOX1 isoform of NADPH oxidase is involved in dysfunction of liver sinusoids in nonalcoholic fatty liver disease.
Non-alcoholic Fatty Liver Disease
[Interaction of polymorphisms of monocyte chemoattractant protein-1 receptor CCR2 gene 190A/G, nicotinamide adenine dinucleotide phosphate oxidase subunit p22phox gene C242T and cigarette smoking increases the risk of nonalcoholic fatty liver disease].
Obesity
Adverse cognitive effects of high-fat diet in a murine model of sleep apnea are mediated by NADPH oxidase activity.
Obesity
Cardiac contractile dysfunction in Lep/Lep obesity is accompanied by NADPH oxidase activation, oxidative modification of sarco(endo)plasmic reticulum Ca2+-ATPase and myosin heavy chain isozyme switch.
Obesity
Critical role of the NADPH oxidase subunit p47phox on vascular TLR expression and neointimal lesion formation in high-fat diet-induced obesity.
Obesity
Differential contribution of Nox1, Nox2 and Nox4 to kidney vascular oxidative stress and endothelial dysfunction in obesity.
Obesity
Endothelial mineralocorticoid receptor activation mediates endothelial dysfunction in diet-induced obesity.
Obesity
Exercise training protects against atherosclerotic risk factors through vascular NADPH oxidase, extracellular signal-regulated kinase 1/2 and stress-activated protein kinase/c-Jun N-terminal kinase downregulation in obese rats.
Obesity
Folic acid supplementation attenuates high fat diet induced hepatic oxidative stress via regulation of NADPH oxidase.
Obesity
Ingested capsaicinoids can prevent low-fat-high-carbohydrate diet and high-fat diet-induced obesity by regulating the NADPH oxidase and Nrf2 pathways.
Obesity
Is leptin involved in phagocytic NADPH oxidase overactivity in obesity? Potential clinical implications.
Obesity
Microvascular Endothelial Dysfunction in Sedentary, Obese Humans Is Mediated by NADPH Oxidase: Influence of Exercise Training.
Obesity
Myeloid-specific deletion of NOX2 prevents the metabolic and neurologic consequences of high fat diet.
Obesity
NOX2 deficiency attenuates markers of adiposopathy and brain injury induced by high-fat diet.
Obesity
Nox2 dependent redox-regulation of Akt and ERK1/2 to promote left ventricular hypertrophy in dietary obesity of mice.
Obesity
Protection from olanzapine-induced metabolic toxicity in mice by acetaminophen and tetrahydroindenoindole.
Obesity
Rac1 is a possible link between obesity and oxidative stress in Chinese overweight adolescents.
Obesity
Spirulina platensis and silicon-enriched spirulina equally improve glucose tolerance and decrease the enzymatic activity of hepatic NADPH oxidase in obesogenic diet-fed rats.
Ocular Hypertension
Investigations into Hypoxia and Oxidative Stress at the Optic Nerve Head in a Rat Model of Glaucoma.
Opportunistic Infections
Haploinsufficiency of NADPH Oxidase Subunit Neutrophil Cytosolic Factor 2 Is Sufficient to Accelerate Full-Blown Lupus in NZM 2328 Mice.
Osteoarthritis
Age-related NADPH Oxidase (arNOX) Activity Correlated with Cartilage Degradation and Bony Changes in Age-related Osteoarthritis.
Osteoarthritis
Genetic dissection of canine hip dysplasia phenotypes and osteoarthritis reveals three novel loci.
Osteoarthritis
p47phox siRNA-Loaded PLGA Nanoparticles Suppress ROS/Oxidative Stress-Induced Chondrocyte Damage in Osteoarthritis.
Osteoarthritis
The anti-inflammatory effects of apocynin, inhibitor of NADPH oxidase, contrasting hyaluronic acid on articular cartilage during the development of osteoarthritis in a rabbit model.
Osteoarthritis, Knee
Age-related NADPH Oxidase (arNOX) Activity Correlated with Cartilage Degradation and Bony Changes in Age-related Osteoarthritis.
Osteoarthritis, Knee
Association of NADPH oxidase p22phox gene C242T, A640G and -930A/G polymorphisms with primary knee osteoarthritis in the Greek population.
Osteoarthritis, Knee
Corrigendum to "The Overexpression of NALP3 Inflammasome in Knee Osteoarthritis Is Associated with Synovial Membrane Prolidase and NADPH Oxidase 2".
Osteolysis
Suppression of NADPH Oxidase Activity May Slow the Expansion of Osteolytic Bone Metastases.
Osteomyelitis
Dysregulated NADPH Oxidase Promotes Bone Damage in Murine Model of Autoinflammatory Osteomyelitis.
Osteoporosis
A novel pyrazole derivative protects from ovariectomy-induced osteoporosis through the inhibition of NADPH oxidase.
Osteoporosis
Protective effect of resveratrol on estrogen deficiency-induced osteoporosis though attenuating NADPH oxidase 4/nuclear factor kappa B pathway by increasing miR-92b-3p expression.
Osteosarcoma
A possible involvement of plasma membrane NAD(P)H oxidase in the switch mechanism of the cell death mode from apoptosis to necrosis in menadione-induced cell injury.
Ototoxicity
Adenosine A1 Receptor Protects Against Cisplatin Ototoxicity by Suppressing the NOX3/STAT1 Inflammatory Pathway in the Cochlea.
Ototoxicity
Ginkgolide B protects against cisplatin-induced ototoxicity: enhancement of Akt-Nrf2-HO-1 signaling and reduction of NADPH oxidase.
Ototoxicity
Roles of NADPH oxidases in Cisplatin-induced reactive oxygen species generation and ototoxicity.
Ovarian Neoplasms
Gomisin L1, a Lignan Isolated from Schisandra Berries, Induces Apoptosis by Regulating NADPH Oxidase in Human Ovarian Cancer Cells.
Ovarian Neoplasms
Reactive oxygen species regulate angiogenesis and tumor growth through vascular endothelial growth factor.
Overweight
Rac1 is a possible link between obesity and oxidative stress in Chinese overweight adolescents.
Pancreatic Neoplasms
Dual Oxidase2 and pancreatic adenocarcinoma: IFN-?-mediated dual oxidase2 overexpression results in H2O2-induced, ERKassociated up-regulation of HIF-1? and VEGF-A.
Pancreatic Neoplasms
Extracellular matrix stimulates reactive oxygen species production and increases pancreatic cancer cell survival through 5-lipoxygenase and NADPH oxidase.
Pancreatic Neoplasms
Inhibition of NADPH oxidase 4 activates apoptosis via the AKT/apoptosis signal-regulating kinase 1 pathway in pancreatic cancer PANC-1 cells.
Pancreatic Neoplasms
NADPH Oxidase Activation in Pancreatic Cancer Cells Is Mediated through Akt-dependent Up-regulation of p22phox.
Pancreatic Neoplasms
NADPH oxidase activation in pancreatic cancer cells is mediated through Akt-dependent up-regulation of p22phox.
Pancreatic Neoplasms
NADPH oxidase promotes pancreatic cancer cell survival via inhibiting JAK2 dephosphorylation by tyrosine phosphatases.
Pancreatic Neoplasms
Nox4-derived ROS signaling contributes to TGF-?-induced epithelial-mesenchymal transition in pancreatic cancer cells.
Pancreatic Neoplasms
Role of Rac1-dependent NADPH oxidase in the growth of pancreatic cancer.
Pancreatitis
NADPH Oxidase Hyperactivity Contributes to Cardiac Dysfunction and Apoptosis in Rats with Severe Experimental Pancreatitis through ROS-Mediated MAPK Signaling Pathway.
Pancreatitis
NADPH oxidase mediates interleukin-6 expression in cerulein-stimulated pancreatic acinar cells.
Pancreatitis
Neutrophils and NADPH oxidase mediate intrapancreatic trypsin activation in murine experimental acute pancreatitis.
Pancreatitis
Pharmacological stimulation of NQO1 decreases NADPH levels and ameliorates acute pancreatitis in mice.
Pancreatitis
Potential role of NADPH oxidase-mediated activation of Jak2/Stat3 and mitogen-activated protein kinases and expression of TGF-?1 in the pathophysiology of acute pancreatitis.
Pancreatitis, Alcoholic
Association Analyses of Genetic Polymorphisms of GSTM1, GSTT1, NQO1, NAT2, LPL, PRSS1, PSTI, and CFTR With Chronic Alcoholic Pancreatitis in Japan.
Parasitemia
Phagocyte-derived reactive oxygen species do not influence the progression of murine blood-stage malaria infections.
Parasitemia
Suppression of Plasmodium chabaudi parasitemia is independent of the action of reactive oxygen intermediates and/or nitric oxide.
Parkinson Disease
Angiotensin AT2 receptor stimulation inhibits activation of NADPH oxidase and ameliorates oxidative stress in rotenone model of Parkinson's disease in CATH.a cells.
Parkinson Disease
Apocyanin, a Microglial NADPH Oxidase Inhibitor Prevents Dopaminergic Neuronal Degeneration in Lipopolysaccharide-Induced Parkinson's Disease Model.
Parkinson Disease
Chronic dichlorvos exposure: microglial activation, proinflammatory cytokines and damage to nigrostriatal dopaminergic system.
Parkinson Disease
Complement receptor 3 mediates NADPH oxidase activation and dopaminergic neurodegeneration through a Src-Erk-dependent pathway.
Parkinson Disease
Critical role of microglial NADPH oxidase-derived free radicals in the in vitro MPTP model of Parkinson's disease.
Parkinson Disease
Inhibition of NADPH oxidase by apocynin prevents learning and memory deficits in a mouse Parkinson's disease model.
Parkinson Disease
Inhibition of NADPH oxidase within midbrain periaqueductal gray decreases pain sensitivity in Parkinson's disease via GABAergic signaling pathway.
Parkinson Disease
Integrin CD11b mediates ?-synuclein-induced activation of NADPH oxidase through a Rho-dependent pathway.
Parkinson Disease
Microglial activation as a priming event leading to paraquat-induced dopaminergic cell degeneration.
Parkinson Disease
NADPH Oxidase 1-Mediated Oxidative Stress Leads to Dopamine Neuron Death in Parkinson's Disease.
Parkinson Disease
NADPH oxidase mediates oxidative stress in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease.
Parkinson Disease
NADPH oxidase promotes Parkinsonian phenotypes by impairing autophagic flux in an mTORC1-independent fashion in a cellular model of Parkinson's disease.
Parkinson Disease
Neuroprotective effect of dextromethorphan in the MPTP Parkinson's disease model: role of NADPH oxidase.
Parkinson Disease
Oral Treatment with the NADPH Oxidase Antagonist Apocynin Mitigates Clinical and Pathological Features of Parkinsonism in the MPTP marmoset Model.
Parkinson Disease
Park 7: A Novel Therapeutic Target for Macrophages in Sepsis-Induced Immunosuppression.
Parkinson Disease
Post-treatment with an ultra-low dose of NADPH oxidase inhibitor diphenyleneiodonium attenuates disease progression in multiple Parkinson's disease models.
Parkinson Disease
Reactive oxygen species and inhibitors of inflammatory enzymes, NADPH oxidase, and iNOS in experimental models of Parkinson's disease.
Parkinson Disease
Subpicomolar diphenyleneiodonium inhibits microglial NADPH oxidase with high specificity and shows great potential as a therapeutic agent for neurodegenerative diseases.
Parkinson Disease
Tanshinone IIA prevents the loss of nigrostriatal dopaminergic neurons by inhibiting NADPH oxidase and iNOS in the MPTP model of Parkinson's disease.
Parkinson Disease
Taurine improves neuron injuries and cognitive impairment in a mouse Parkinson's disease model through inhibition of microglial activation.
Parkinsonian Disorders
Oral Treatment with the NADPH Oxidase Antagonist Apocynin Mitigates Clinical and Pathological Features of Parkinsonism in the MPTP marmoset Model.
Periodontitis
Effect of resveratrol on the progression of experimental periodontitis in an ovariectomized rat model of osteoporosis: Morphometric, immune-enzymatic, and gene expression analysis.
Periodontitis
NADPH Oxidase Contributes to Resistance against Aggregatibacter actinomycetemcomitans-Induced Periodontitis in Mice.
Peripheral Arterial Disease
Low-density lipoprotein apheresis for haemodialysis patients with peripheral arterial disease reduces reactive oxygen species production via suppression of NADPH oxidase gene expression in leucocytes.
Peritoneal Fibrosis
NADPH oxidase-dependent formation of reactive oxygen species contributes to angiotensin II-induced epithelial-mesenchymal transition in rat peritoneal mesothelial cells.
Peritonitis
An efferocytosis-induced, IL-4-dependent macrophage-iNKT cell circuit suppresses sterile inflammation and is defective in murine CGD.
Peritonitis
HMGB1 induces neutrophil dysfunction in experimental sepsis and in patients who survive septic shock.
Peritonitis
NADPH oxidase-dependent generation of lysophosphatidylserine enhances clearance of activated and dying neutrophils via G2A.
Peroxisomal Disorders
Very long chain fatty acids activate NADPH oxidase in human dermal fibroblasts.
Phenylketonurias
Mechanisms regulating superoxide generation in experimental models of phenylketonuria: An essential role of NADPH oxidase.
Pheochromocytoma
Essential role of Rac1/NADPH oxidase in nerve growth factor induction of TRPV1 expression.
Photosensitivity Disorders
Inhibition of neutrophil superoxide generation by hypericin, an antiretroviral agent.
Plant Diseases
RACK1 Functions in Rice Innate Immunity by Interacting with the Rac1 Immune Complex.
Pneumonia
Blockade of class IA phosphoinositide 3-kinase in neutrophils prevents NADPH oxidase activation- and adhesion-dependent inflammation.
Pneumonia
Critical role of mitochondrial oxidative stress in acid aspiration induced ALI in mice.
Pneumonia
Dynamin 2 and c-Abl are novel regulators of hyperoxia-mediated NADPH oxidase activation and ROS production in caveolin-enriched microdomains of the endothelium.
Pneumonia
Francisella tularensis directly interacts with the endothelium and recruits neutrophils with a blunted inflammatory phenotype.
Pneumonia
Genetic ablation of NADPH oxidase enhances susceptibility to cigarette smoke-induced lung inflammation and emphysema in mice.
Pneumonia
Genetic Phagocyte NADPH Oxidase Deficiency Enhances Nonviable Candida albicans-Induced Inflammation in Mouse Lungs.
Pneumonia
Increased accumulation of neutrophils and decreased fibrosis in the lung of NADPH oxidase-deficient C57BL/6 mice exposed to carbon nanotubes.
Pneumonia
Inhibition of Nox2 oxidase activity ameliorates influenza A virus-induced lung inflammation.
Pneumonia
Inhibition of the phospholipase A2 activity of peroxiredoxin 6 prevents lung damage with exposure to hyperoxia.
Pneumonia
Metal rich particulate matter impairs acetylcholine-mediated vasorelaxation of microvessels in mice.
Pneumonia
Monocyte- and Macrophage-Targeted NADPH Oxidase Mediates Antifungal Host Defense and Regulation of Acute Inflammation in Mice.
Pneumonia
Mycobacterial infection induces higher interleukin-1? and dysregulated lung inflammation in mice with defective leukocyte NADPH oxidase.
Pneumonia
NADPH oxidase and Nrf2 regulate gastric aspiration-induced inflammation and acute lung injury.
Pneumonia
NADPH Oxidase Limits Lipopolysaccharide-Induced Lung Inflammation and Injury in Mice through Reduction-Oxidation Regulation of NF-?B Activity.
Pneumonia
NADPH oxidase promotes neutrophil extracellular trap formation in pulmonary aspergillosis.
Pneumonia
Nox1 oxidase suppresses influenza a virus-induced lung inflammation and oxidative stress.
Pneumonia
p47phox deficiency impairs NF-kappa B activation and host defense in Pseudomonas pneumonia.
Pneumonia
Reactive oxygen species regulate neutrophil recruitment and survival in pneumococcal pneumonia.
Pneumonia
Redox regulation of lung inflammation: role of NADPH oxidase and NF-kappaB signalling.
Pneumonia
Redox-sensitive regulation of macrophage-inducible nitric oxide synthase expression in vitro does not correlate with the failure of apocynin to prevent lung inflammation induced by endotoxin.
Pneumonia
Regulation of NADPH Oxidase in Vascular Endothelium: The Role of Phospholipases, Protein Kinases, and Cytoskeletal Proteins.
Pneumonia
Resveratrol and curcumin reduce the respiratory burst of Chlamydia-primed THP-1 cells.
Pre-Eclampsia
Activin and NADPH-oxidase in preeclampsia: insights from in vitro and murine studies.
Pre-Eclampsia
AOPPs (advanced oxidation protein products) promote apoptosis in trophoblastic cells through interference with NADPH oxidase signaling: implications for preeclampsia.
Pre-Eclampsia
AT1 receptor agonistic antibodies from preeclamptic patients stimulate NADPH oxidase.
Pre-Eclampsia
Expression of NADPH oxidase isoform 1 (Nox1) in human placenta: involvement in preeclampsia.
Pre-Eclampsia
Human serum albumin and oxidative stress in preeclamptic women and the mechanism of albumin for stress reduction.
Pre-Eclampsia
NADPH oxidase 2-derived superoxide downregulates endothelial KCa3.1 in preeclampsia.
Pre-Eclampsia
NADPH oxidase activity in preeclampsia with immortalized lymphoblasts used as models.
Pre-Eclampsia
Neutrophil activation and production of reactive oxygen species in pre-eclampsia.
Pre-Eclampsia
Protein Kinase C Epsilon Contributes to NADPH Oxidase Activation in a Pre-Eclampsia Lymphoblast Cell Model.
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Intracellular reactive oxygen species are essential for PI3K/Akt/mTOR-dependent IL-7-mediated viability of T-cell acute lymphoblastic leukemia cells.
Presbycusis
NADPH oxidase inhibitor apocynin decreases mitochondrial dysfunction and apoptosis in the ventral cochlear nucleus of D-galactose-induced aging model in rats.
Priapism
Beneficial effect of the nitric oxide donor compound 3-(1,3-dioxoisoindolin-2-yl)benzyl nitrate on dysregulated phosphodiesterase 5, NADPH oxidase and nitrosative stress in the sickle cell mouse penis: implication for priapism treatment.
Priapism
Molecular Analysis of Erection Regulatory Factors in Sickle Cell Disease-Associated Priapism in Human Penis.
Primary Dysautonomias
ACE2-Mediated Reduction of Oxidative Stress in the Central Nervous System Is Associated with Improvement of Autonomic Function.
Primary Immunodeficiency Diseases
A novel variant in the neutrophil cytosolic factor 2 (NCF2) gene results in severe disseminated BCG infectious disease: A clinical report and literature review.
Primary Immunodeficiency Diseases
Altered Pattern of Naïve and Memory B cells and B1 Cells in Patients with Chronic Granulomatous Disease.
Primary Immunodeficiency Diseases
Aspergillus nidulans infection in a patient with chronic granulomatous disease.
Primary Immunodeficiency Diseases
Investigation into the relationship between calyculin A-mediated potentiation of NADPH oxidase activity and inhibition of store-operated uptake of calcium by human neutrophils.
Primary Immunodeficiency Diseases
Molecular quality control machinery contributes to the leukocyte NADPH oxidase deficiency in chronic granulomatous disease.
Primary Immunodeficiency Diseases
Novel NCF2 Mutation Causing Chronic Granulomatous Disease.
Primary Immunodeficiency Diseases
Ocular manifestations in chronic granulomatous disease in Saudi Arabia.
Primary Immunodeficiency Diseases
Respiratory complications after haematopoietic stem cell transplantation in a patient with chronic granulomatous disease.
Primary Immunodeficiency Diseases
Study of naïve and memory cells in a cohort of Egyptian chronic granulomatous disease patients.
Primary Immunodeficiency Diseases
The three CYBA variants (rs4673, rs1049254 and rs1049255) are benign: new evidence from a patient with CGD.
Prostatic Hyperplasia
[Evaluation of the expression of p22 phox subunit of NADPH oxidase (NOX) in prostate cancer and benign prostatic hyperplasia: a comparative study]
Prostatic Intraepithelial Neoplasia
Loss of NADPH quinone oxidoreductase in the prostate and enhanced serum levels of cytokine-induced neutrophil chemoattractant 2alpha in hormone-stimulated noble rats: potential role in prostatic intraepithelial neoplasia development.
Prostatic Neoplasms
A NADPH oxidase-dependent redox signaling pathway mediates the selective radiosensitization effect of parthenolide in prostate cancer cells.
Prostatic Neoplasms
Adenosine A(3) receptor suppresses prostate cancer metastasis by inhibiting NADPH oxidase activity.
Prostatic Neoplasms
Androgens induce oxidative stress and radiation resistance in prostate cancer cells though NADPH oxidase.
Prostatic Neoplasms
Apocynin, an NADPH oxidase inhibitor, suppresses progression of prostate cancer via Rac1 dephosphorylation.
Prostatic Neoplasms
Cisplatin induces production of reactive oxygen species via NADPH oxidase activation in human prostate cancer cells.
Prostatic Neoplasms
Cysteine (C)-X-C Receptor 4 Regulates NADPH Oxidase-2 During Oxidative Stress in Prostate Cancer Cells.
Prostatic Neoplasms
Effects of iodonium-class flavin dehydrogenase inhibitors on growth, reactive oxygen production, cell cycle progression, NADPH oxidase 1 levels, and gene expression in human colon cancer cells and xenografts.
Prostatic Neoplasms
Graviola inhibits hypoxia-induced NADPH oxidase activity in prostate cancer cells reducing their proliferation and clonogenicity.
Prostatic Neoplasms
KEAP1 is a redox sensitive target that arbitrates the opposing radiosensitive effects of parthenolide in normal and cancer cells.
Prostatic Neoplasms
NADPH oxidase subunit p22(phox)-mediated reactive oxygen species contribute to angiogenesis and tumor growth through AKT and ERK1/2 signaling pathways in prostate cancer.
Prostatic Neoplasms
NOX2 oxidase expressed in endosomes promotes cell proliferation and prostate tumour development.
Prostatic Neoplasms
PKC? activation mediates angiogenesis via NADPH oxidase activity in PC-3 prostate cancer cells.
Prostatic Neoplasms
[Evaluation of the expression of p22 phox subunit of NADPH oxidase (NOX) in prostate cancer and benign prostatic hyperplasia: a comparative study]
protein acetyllysine n-acetyltransferase deficiency
Shared pathways for neuroprogression and somatoprogression in neuropsychiatric disorders.
protein-tyrosine-phosphatase deficiency
circ-PRKCB acts as a ceRNA to regulate p66Shc-mediated oxidative stress in intestinal ischemia/reperfusion.
Proteinuria
Angiotensin-(1-7) prevents diabetes-induced attenuation in PPAR-gamma and catalase activities.
Proteinuria
AT1 receptor-mediated augmentation of angiotensinogen, oxidative stress, and inflammation in ANG II-salt hypertension.
Proteinuria
Dual blockade of aldosterone and angiotensin II additively suppresses TGF-beta and NADPH oxidase in the hypertensive kidney.
Proteinuria
Effects of Dietary Salt on Intrarenal Angiotensin System, NAD(P)H Oxidase, COX-2, MCP-1 and PAI-1 Expressions and NF-kappaB Activity in Salt-Sensitive and -Resistant Rat Kidneys.
Proteinuria
NADPH oxidase-derived ROS contributes to upregulation of TRPC6 expression in puromycin aminonucleoside-induced podocyte injury.
Proteinuria
NADPH oxidase-mediated triggering of inflammasome activation in mouse podocytes and glomeruli during hyperhomocysteinemia.
Proteinuria
Nebivolol reduces proteinuria and renal NADPH oxidase-generated reactive oxygen species in the transgenic Ren2 rat.
Proteinuria
Potential sources of oxidative stress that induce postexercise proteinuria in rats.
Proteinuria
Regression of glomerular and tubulointerstitial injuries by dietary salt reduction with combination therapy of angiotensin II receptor blocker and calcium channel blocker in Dahl salt-sensitive rats.
Proteinuria
[Effect of NADPH oxidase inhibitor apocynin on the exercise induced proteinuria in rats].
Psoriasis
NADPH oxidase inhibition rescues keratinocytes from elevated oxidative stress in a 2D atopic dermatitis and psoriasis model.
Pulmonary Arterial Hypertension
NADPH oxidase: its potential role in promotion of pulmonary arterial hypertension.
Pulmonary Arterial Hypertension
Right-ventricular failure is associated with increased mitochondrial complex II activity and production of reactive oxygen species.
Pulmonary Aspergillosis
Low Interleukin-17A Production in Response to Fungal Pathogens in Patients with Chronic Granulomatous Disease.
Pulmonary Aspergillosis
Monocyte- and Macrophage-Targeted NADPH Oxidase Mediates Antifungal Host Defense and Regulation of Acute Inflammation in Mice.
Pulmonary Aspergillosis
NADPH oxidase promotes neutrophil extracellular trap formation in pulmonary aspergillosis.
Pulmonary Disease, Chronic Obstructive
Airway smooth muscle NOX4 is upregulated and modulates ROS generation in COPD.
Pulmonary Disease, Chronic Obstructive
Author Correction: NADPH oxidase subunit NOXO1 is a target for emphysema treatment in COPD.
Pulmonary Disease, Chronic Obstructive
Downregulation of epithelial DUOX1 in chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
Gene expression profiling in lung tissues from mice exposed to cigarette smoke, lipopolysaccharide, or smoke plus lipopolysaccharide by inhalation.
Pulmonary Disease, Chronic Obstructive
LPS induced inflammatory responses in human peripheral blood mononuclear cells is mediated through NOX4 and Gi? dependent PI-3kinase signalling.
Pulmonary Disease, Chronic Obstructive
NADPH oxidase subunit NOXO1 is a target for emphysema treatment in COPD.
Pulmonary Disease, Chronic Obstructive
NOX4 expression and distal arteriolar remodeling correlate with pulmonary hypertension in COPD.
Pulmonary Disease, Chronic Obstructive
Nrf2 expression is increased in peripheral blood mononuclear cells derived from mild-moderate ex-smoker COPD patients with persistent oxidative stress.
Pulmonary Fibrosis
A key role for NOX4 in epithelial cell death during development of lung fibrosis.
Pulmonary Fibrosis
Mechanisms of pulmonary fibrosis: role of activated myofibroblasts and NADPH oxidase.
Pulmonary Fibrosis
Metabolomic study on bleomycin and polyhexamethylene guanidine phosphate-induced pulmonary fibrosis mice models.
Pulmonary Fibrosis
NADPH Oxidase-Dependent NLRP3 Inflammasome Activation and its Important Role in Lung Fibrosis by Multiwalled Carbon Nanotubes.
Pulmonary Fibrosis
Osthole Attenuates Bleomycin-Induced Pulmonary Fibrosis by Modulating NADPH Oxidase 4-Derived Oxidative Stress in Mice.
Pulmonary Fibrosis
Pivotal Role of Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 in Inflammatory Pulmonary Diseases.
Q Fever
Both inducible nitric oxide synthase and NADPH oxidase contribute to the control of virulent phase I Coxiella burnetii infections.
Renal Artery Obstruction
Reactive oxygen species impair sympathetic vasoregulation in skeletal muscle in angiotensin II-dependent hypertension.
Renal Insufficiency
Activation of NADPH oxidase by AGE links oxidant stress to altered gene expression via RAGE.
Renal Insufficiency
Depressed phagocytosis in hemodialyzed patients: in vivo and in vitro mechanisms.
Renal Insufficiency
Oxidative stress and dysregulation of superoxide dismutase and NADPH oxidase in renal insufficiency.
Renal Insufficiency
Protective role of NAD(P)H:quinone oxidoreductase 1 (NQO1) in cisplatin-induced nephrotoxicity.
Renal Insufficiency, Chronic
Differential contribution of Nox1, Nox2 and Nox4 to kidney vascular oxidative stress and endothelial dysfunction in obesity.
Renal Insufficiency, Chronic
Oxidative stress, inflammation, and peritoneal dialysis: A molecular biology approach.
Reperfusion Injury
Alpha-Lipoic Acid Attenuates Cerebral Ischemia and Reperfusion Injury via Insulin Receptor and PI3K/Akt-Dependent Inhibition of NADPH Oxidase.
Reperfusion Injury
Annexin peptide Ac2-26 suppresses TNF?-induced inflammatory responses via inhibition of Rac1-dependent NADPH oxidase in human endothelial cells.
Reperfusion Injury
Astroglial NF-?B mediates oxidative stress by regulation of NADPH oxidase in a model of retinal ischemia reperfusion injury.
Reperfusion Injury
Corrigendum to "Propofol Attenuates Small Intestinal Ischemia Reperfusion Injury through Inhibiting NADPH Oxidase Mediated Mast Cell Activation".
Reperfusion Injury
CTRP9 protein protects against myocardial injury following ischemia-reperfusion through AMP-activated protein kinase (AMPK)-dependent mechanism.
Reperfusion Injury
Hyperbaric oxygen preconditioning and the role of NADPH oxidase inhibition in postischemic acute kidney injury induced in spontaneously hypertensive rats.
Reperfusion Injury
Inhibition of NADPH oxidase alleviates germ cell apoptosis and ER stress during testicular ischemia reperfusion injury.
Reperfusion Injury
Ischemic stroke injury is reduced in mice lacking a functional NADPH oxidase.
Reperfusion Injury
Limb Remote Ischemic Postconditioning Reduces Ischemia-Reperfusion Injury by Inhibiting NADPH Oxidase Activation and MyD88-TRAF6-P38MAP-Kinase Pathway of Neutrophils.
Reperfusion Injury
Megakaryocytic Leukemia 1 (MKL1) Bridges Epigenetic Activation of NADPH Oxidase in Macrophages to Cardiac Ischemia-Reperfusion Injury.
Reperfusion Injury
NADPH oxidase in bone marrow-derived cells mediates pulmonary ischemia-reperfusion injury.
Reperfusion Injury
NOD2 is involved in the inflammatory response after cerebral ischemia-reperfusion injury and triggers NADPH oxidase 2-derived reactive oxygen species.
Reperfusion Injury
NOX2 Activation of NKT Cells is Blocked by Adenosine A2A Receptor to Inhibit Lung Reperfusion Injury.
Reperfusion Injury
Propofol Attenuates Small Intestinal Ischemia Reperfusion Injury through Inhibiting NADPH Oxidase Mediated Mast Cell Activation.
Reperfusion Injury
Protection From Cardiac Ischemia-Reperfusion Injury by Epigenetic Regulation of NADPH Oxidase.
Reperfusion Injury
Salviaolate Protects Rat Brain from Ischemia-Reperfusion Injury through Inhibition of NADPH Oxidase.
Reperfusion Injury
The Protective Effect of Apocynin on Testicular Ischemia-Reperfusion Injury.
Reperfusion Injury
Zinc pyrithione salvages reperfusion injury by inhibiting NADPH oxidase activation in cardiomyocytes.
Respiratory Insufficiency
NADPH oxidase activity is necessary for acute intermittent hypoxia-induced phrenic long-term facilitation.
Respiratory Tract Infections
Host defense activity in various hosts. Human neutrophil NADPH oxidase activity.
Respiratory Tract Infections
PPAR? Regulates Chronic Alcohol-induced Alveolar Macrophage Dysfunction.
Respiratory Tract Infections
[Effects of respiratory tract infections and antibiotic therapy on NADPH oxidase activity]
Retinal Degeneration
Microglial NADPH oxidase activation mediates rod cell death in the retinal degeneration in rd mice.
Retinal Diseases
Nrf2 promotes reparative angiogenesis through regulation of NADPH oxidase-2 in oxygen-induced retinopathy.
Retinal Neovascularization
Involvement of Nox2 NADPH oxidase in retinal neovascularization.
Retinal Neovascularization
NADPH oxidase 4-derived H2O2 promotes aberrant retinal neovascularization via activation of VEGF receptor 2 pathway in oxygen-induced retinopathy.
Retinitis Pigmentosa
NADPH oxidase plays a central role in cone cell death in retinitis pigmentosa.
Rheumatic Diseases
Priming of NADPH oxidase by tumor necrosis factor alpha in patients with inflammatory and autoimmune rheumatic diseases.
Rheumatic Fever
NADPH oxidase activity in the monocytes and neutrophils of patients with rheumatic fever.
Rhinitis, Allergic
Overexpression of the superoxide anion and NADPH oxidase isoforms 1 and 4 (NOX1 and NOX4) in allergic nasal mucosa.
Riboflavin Deficiency
Effect of riboflavin or pyridoxine deficiency on inflammatory response.
Scleroderma, Systemic
Intracellular free radical production by peripheral blood T lymphocytes from patients with systemic sclerosis: role of NADPH oxidase and ERK1/2.
Scleroderma, Systemic
Lack of association of eNOS (G894T) and p22phox NADPH oxidase subunit (C242T) polymorphisms with systemic sclerosis in a cohort of French Caucasian patients.
Scleroderma, Systemic
Lack of association of eNOS(G894T) and p22phox NADPH oxidase submit (C242T) polymorphisms with systemic sclerosis in a cohort of French Caucasian patients.
Seizures
Activation of NADPH oxidase and extracellular superoxide production in seizure-induced hippocampal damage.
Seizures
Post-treatment of an NADPH oxidase inhibitor prevents seizure-induced neuronal death.
Sepsis
Co-morbidity and systemic inflammation as drivers of cognitive decline: new experimental models adopting a broader paradigm in dementia research.
Sepsis
Dynamin 2 and c-Abl are novel regulators of hyperoxia-mediated NADPH oxidase activation and ROS production in caveolin-enriched microdomains of the endothelium.
Sepsis
Female X-chromosome mosaicism for NOX2 deficiency presents unique inflammatory phenotype and improves outcome in polymicrobial sepsis.
Sepsis
HMGB1 induces neutrophil dysfunction in experimental sepsis and in patients who survive septic shock.
Sepsis
iNOS expression requires NADPH oxidase-dependent redox signaling in microvascular endothelial cells.
Sepsis
Interplay between Nox2 Activity and Platelet Activation in Patients with Sepsis and Septic Shock: A Prospective Study.
Sepsis
NADPH oxidase contributes to conversion of cardiac myocytes to a proinflammatory phenotype in sepsis.
Sepsis
Neurodegenerative evidence in mice brains with cecal ligation and puncture-induced sepsis: preventive effect of the free radical scavenger edaravone.
Sepsis
Park7 interacts with p47(phox) to direct NADPH oxidase-dependent ROS production and protect against sepsis.
Sepsis
Platelet-derived exosomes of septic individuals possess proapoptotic NAD(P)H oxidase activity: A novel vascular redox pathway.
Sepsis
Protective role of reactive oxygen species in endotoxin-induced lung inflammation through modulation of IL-10 expression.
Sepsis
Regulation of NADPH Oxidase in Vascular Endothelium: The Role of Phospholipases, Protein Kinases, and Cytoskeletal Proteins.
Sepsis
Role of NADPH oxidase in the mechanism of lung neutrophil sequestration and microvessel injury induced by Gram-negative sepsis: studies in p47phox-/- and gp91phox-/- mice.
Sepsis
SYNCRIP-Dependent Nox2 mRNA Destabilization Impairs ROS Formation in M2-Polarized Macrophages.
Sepsis
The role of Nox2-derived ROS in the development of cognitive impairment after sepsis.
Shock, Septic
HMGB1 induces neutrophil dysfunction in experimental sepsis and in patients who survive septic shock.
Shock, Septic
Interplay between Nox2 Activity and Platelet Activation in Patients with Sepsis and Septic Shock: A Prospective Study.
Shock, Septic
Lipopolysaccharide-induced radical formation in the striatum is abolished in Nox2 gp91phox-deficient mice.
Silicotuberculosis
A synergistic interaction between Bacillus Calmette-Guérin (BCG) and NADPH oxidase stimulants on the production of reactive oxygen metabolites by human mononuclear phagocytes.
Sleep Apnea Syndromes
Adverse cognitive effects of high-fat diet in a murine model of sleep apnea are mediated by NADPH oxidase activity.
Sleep Apnea Syndromes
Endothelial dysfunction and oxidative stress in children with sleep disordered breathing: role of NADPH oxidase.
Sleep Apnea Syndromes
Green tea catechin polyphenols attenuate behavioral and oxidative responses to intermittent hypoxia.
Sleep Apnea Syndromes
Intermittent hypoxia-induced cognitive deficits are mediated by NADPH oxidase activity in a murine model of sleep apnea.
Sleep Apnea Syndromes
NADPH Oxidase Activation: A Mechanism of Erectile Dysfunction in a Rat Model of Sleep Apnea.
Sleep Apnea Syndromes
NADPH oxidase mediates hypersomnolence and brain oxidative injury in a murine model of sleep apnea.
Sleep Apnea Syndromes
Selective loss of catecholaminergic wake active neurons in a murine sleep apnea model.
Sleep Apnea Syndromes
Sleep Fragmentation Induces Cognitive Deficits Via NADPH Oxidase-Dependent Pathways In Mouse.
Sleep Apnea, Obstructive
Cognitive function in prepubertal children with obstructive sleep apnea: a modifying role for NADPH oxidase p22 subunit gene polymorphisms?
Sleep Apnea, Obstructive
Effect of NADPH oxidase inhibitor apocynin on the expression of hypoxia-induced factor-1? and endothelin-1 in rat carotid body exposed to chronic intermittent hypoxia.
Sleep Apnea, Obstructive
NADPH oxidase mediates hypersomnolence and brain oxidative injury in a murine model of sleep apnea.
Sleep Apnea, Obstructive
Relationship between reduced nicotinamide adenine dinucleotide phosphate oxidase subunit p22phox gene polymorphism and obstructive sleep apnea-hypopnea syndrome in the Chinese Han population.
Sleep Apnea, Obstructive
[Effect of NADPH oxidase activity inhibitor apocynin on blood pressure in rats exposed to chronic intermittent hypoxia and the possible mechanisms]
Sleep Apnea, Obstructive
[Nicotinamide-adenine dinucleotide phosphate oxidase p22phox expression in induced sputum cells for patients with obstructive sleep apnea hypopnea syndrome.]
Sleep Deprivation
Sleep deprivation alters neutrophil functions and levels of Th1-related chemokines and CD4+ T cells in the blood.
Sleep Deprivation
Sleep Fragmentation Induces Cognitive Deficits Via NADPH Oxidase-Dependent Pathways In Mouse.
Sleep Deprivation
Sleep fragmentation promotes NADPH oxidase 2-mediated adipose tissue inflammation leading to insulin resistance in mice.
Sleep Wake Disorders
Adverse cognitive effects of high-fat diet in a murine model of sleep apnea are mediated by NADPH oxidase activity.
Small Cell Lung Carcinoma
NADPH-oxidase and a hydrogen peroxide-sensitive K+ channel may function as an oxygen sensor complex in airway chemoreceptors and small cell lung carcinoma cell lines.
Small Cell Lung Carcinoma
NOX2 (gp91 phox) is a predominant O2 sensor in a human airway chemoreceptor cell line: biochemical, molecular and electrophysiological evidence.
Spasm
The endothelin receptor antagonist CPU0213 is more effective than aminoguanidine to attenuate isoproterenol-induced vascular abnormality by suppressing overexpression of NADPH Oxidas, ETA, ETB, and MMP9 in the vasculature.
sphingosine kinase deficiency
Sphingosine Kinase 1 Deficiency Confers Protection against Hyperoxia-Induced Bronchopulmonary Dysplasia in a Murine Model: Role of S1P Signaling and Nox Proteins.
Spinal Cord Injuries
Characterization of the expression and inflammatory activity of NADPH oxidase after spinal cord injury.
Spinal Cord Injuries
Effect of Apocynin, an inhibitor of NADPH oxidase, in the inflammatory process induced by an experimental model of spinal cord injury.
Spinal Cord Injuries
Inhibition of NADPH oxidase activation in oligodendrocytes reduces cytotoxicity following trauma.
Spinal Cord Injuries
Inhibition of NOX2 reduces locomotor impairment, inflammation, and oxidative stress after spinal cord injury.
Spinal Cord Injuries
NADPH oxidase isoform expression is temporally regulated and may contribute to microglial/macrophage polarization after spinal cord injury.
Spinal Cord Injuries
Reducing age-dependent monocyte-derived macrophage activation contributes to the therapeutic efficacy of NADPH oxidase inhibition in spinal cord injury.
Spinocerebellar Ataxias
Expanded ataxin-7 cause toxicity by inducing ROS production from NADPH oxidase complexes in a stable inducible Spinocerebellar ataxia type 7 (SCA7) model.
Spondylarthropathies
NADPH oxidase priming and p47phox phosphorylation in neutrophils from synovial fluid of patients with rheumatoid arthritis and spondylarthropathy.
Squamous Cell Carcinoma of Head and Neck
miR-372 inhibits p62 in head and neck squamous cell carcinoma in vitro and in vivo.
Squamous Cell Carcinoma of Head and Neck
NADPH oxidase and uncoupled nitric oxide synthase are major sources of reactive oxygen species in oral squamous cell carcinoma. Potential implications for immune regulation in high oxidative stress conditions.
Staphylococcal Infections
Pivotal Advance: Eosinophilia in the MES rat strain is caused by a loss-of-function mutation in the gene for cytochrome b(-245), alpha polypeptide (Cyba).
Starvation
The non-host pathogen Botrytis cinerea enhances glucose transport in Pinus pinaster suspension-cultured cells.
Status Epilepticus
Activation of NADPH oxidase and extracellular superoxide production in seizure-induced hippocampal damage.
Status Epilepticus
Reactive oxygen species generated by NADPH oxidase are involved in neurodegeneration in the pilocarpine model of temporal lobe epilepsy.
Stomach Neoplasms
Genetic variant of the p22PHOX component of NADPH oxidase C242T and the incidence of gastric cancer in Japan.
Stomach Neoplasms
TNF-?/TNFR1 signaling promotes gastric tumorigenesis through induction of Noxo1 and Gna14 in tumor cells.
Stomach Ulcer
Genetic variant of the p22PHOX component of NADPH oxidase C242T and the incidence of gastric cancer in Japan.
Stroke
Apocynin protects against global cerebral ischemia-reperfusion-induced oxidative stress and injury in the gerbil hippocampus.
Stroke
Early increase of Nox4 NADPH oxidase and superoxide generation following endothelin-1-induced stroke in conscious rats.
Stroke
Estrogen attenuates ischemic oxidative damage via an estrogen receptor alpha-mediated inhibition of NADPH oxidase activation.
Stroke
Excess salt causes cerebral neuronal apoptosis and inflammation in stroke-prone hypertensive rats through angiotensin II-induced NADPH oxidase activation.
Stroke
Icariin ameliorates angiotensin II-induced cerebrovascular remodeling by inhibiting Nox2-containing NADPH oxidase activation.
Stroke
Is there a clinical role for oxidative stress biomarkers in atherosclerotic diseases?
Stroke
NADPH oxidase and angiogenesis following endothelin-1 induced stroke in rats: role for nox2 in brain repair.
Stroke
NADPH Oxidase as a Therapeutic Target for Neuroprotection against Ischaemic Stroke: Future Perspectives.
Stroke
NADPH oxidase plays a central role in blood-brain barrier damage in experimental stroke.
Stroke
Neuroprotection conferred by post-ischemia ethanol therapy in experimental stroke: an inhibitory effect on hyperglycolysis and NADPH oxidase activation.
Stroke
Oral phycocyanobilin may diminish the pathogenicity of activated brain microglia in neurodegenerative disorders.
Stroke
Oxidative Stress in Ischemic Brain Damage: Mechanisms of Cell Death and Potential Molecular Targets for Neuroprotection.
Stroke
Pioglitazone exerts protective effects against stroke in stroke-prone spontaneously hypertensive rats, independently of blood pressure.
Stroke
Regulation of NADPH oxidase subunit p22(phox) by NF-kB in human aortic smooth muscle cells.
Stroke
Role of Rac1 GTPase in NADPH oxidase activation and cognitive impairment following cerebral ischemia in the rat.
Stroke
Targeting oxidative stress injury after ischemic stroke in conscious rats: limited benefits with apocynin highlight the need to incorporate long term recovery.
Stroke
The role of NADPH oxidase in vascular disease--hypertension, atherosclerosis & stroke.
Subarachnoid Hemorrhage
Hyperbaric oxygen suppresses NADPH oxidase in a rat subarachnoid hemorrhage model.
Subarachnoid Hemorrhage
Inhibition of NADPH oxidase attenuates vasospasm after experimental subarachnoid hemorrhage in rats.
Subarachnoid Hemorrhage
Retraction. Inhibition of NADPH oxidase attenuates vasospasm after experimental subarachnoid hemorrhage in rats.
Synovitis
Deficiency of NADPH oxidase components p47phox and gp91phox caused granulomatous synovitis and increased connective tissue destruction in experimental arthritis models.
Synucleinopathies
Integrin CD11b mediates ?-synuclein-induced activation of NADPH oxidase through a Rho-dependent pathway.
Tachycardia
Exercise and tachycardia increase NADPH oxidase and ryanodine receptor-2 activity: possible role in cardioprotection.
Tachycardia
Response of various conduit arteries in tachycardia- and volume overload-induced heart failure.
Tachycardia
Tachycardia increases NADPH oxidase activity and RyR2 S-glutathionylation in ventricular muscle.
Tetanus
SNARE-mediated rapid lysosome fusion in membrane raft clustering and dysfunction of bovine coronary arterial endothelium.
Thrombocythemia, Essential
Gene Polymorphism of Xenobiotic Biotransformation Enzymes in Patients with Classical Ph-Negative Myeloproliferative Neoplasms.
Thrombocytopenia
Inhibition of NADPH oxidase blocks NETosis and reduces thrombosis in heparin-induced thrombocytopenia.
Thrombosis
Amyloid Peptide ?1-42 Induces Integrin ?IIb?3 Activation, Platelet Adhesion, and Thrombus Formation in a NADPH Oxidase-Dependent Manner.
Thrombosis
Class III PI3K Positively Regulates Platelet Activation and Thrombosis via PI(3)P-Directed Function of NADPH Oxidase.
Thrombosis
Inhibition of NADPH oxidase blocks NETosis and reduces thrombosis in heparin-induced thrombocytopenia.
Thrombosis
NADPH oxidase 2 (NOX2): A key target of oxidative stress-mediated platelet activation and thrombosis.
Thrombosis
Nox2 NADPH oxidase is dispensable for platelet activation or arterial thrombosis in mice.
Thrombosis
Pigment epithelium-derived factor (PEDF) administration inhibits occlusive thrombus formation in rats: a possible participation of reduced intraplatelet PEDF in thrombosis of acute coronary syndromes.
Thrombosis
Platelet CD36 promotes thrombosis by activating redox sensor ERK5 in hyperlipidemic conditions.
Thyroid Cancer, Papillary
NADPH Oxidase NOX4 Is a Critical Mediator of BRAF(V600E)-Induced Downregulation of the Sodium/Iodide Symporter in Papillary Thyroid Carcinomas.
Thyroid Neoplasms
NADPH oxidase NOX4 is a glycolytic regulator through mROS-HIF1? axis in thyroid carcinomas.
Thyroid Neoplasms
Regulation of NADPH oxidase NOX4 by delta iodolactone (IL-?) in thyroid cancer cells.
Thyroid Nodule
Ca(2+)/nicotinamide adenine dinucleotide phosphate-dependent H(2)O(2) generation is inhibited by iodide in human thyroids.
Trichosporonosis
Disseminated trichosporonosis in a murine model of chronic granulomatous disease.
Tuberculosis
A Novel Genetic Variation in NCF2, the Core Component of NADPH Oxidase, Contributes to the Susceptibility of Tuberculosis in Western Chinese Han Population.
Tuberculosis
A synergistic interaction between Bacillus Calmette-Guérin (BCG) and NADPH oxidase stimulants on the production of reactive oxygen metabolites by human mononuclear phagocytes.
Tuberculosis
Glycation of calmodulin binding domain of iNOS may increase the chance of occurrence of tuberculosis in chronic diabetic state.
Tuberculosis
Mycobacterium tuberculosis PPE2 Protein Interacts with p67phox and Inhibits Reactive Oxygen Species Production.
Tuberculosis
N-acetyl-cysteine exhibits potent anti-mycobacterial activity in addition to its known anti-oxidative functions.
Tuberculosis
Vitamin D rescues impaired Mycobacterium tuberculosis-mediated tumor necrosis factor release in macrophages of HIV-seropositive individuals through an enhanced Toll-like receptor signaling pathway in vitro.
Tuberous Sclerosis
Tuberin regulates reactive oxygen species in renal proximal cells, kidney from rodents, and kidney from patients with tuberous sclerosis complex.
Tularemia
Francisella tularensis directly interacts with the endothelium and recruits neutrophils with a blunted inflammatory phenotype.
Uremia
NADPH oxidase activity is associated with cardiac osteopontin and pro-collagen type I expression in uremia.
Uterine Cervical Neoplasms
Dual oxidase 1 and NADPH oxidase 2 exert favorable effects in cervical cancer patients by activating immune response.
Varicose Veins
Compression stockings attenuate the expression of proteins associated with vascular damage in human varicose veins.
Vascular Calcification
Novel targets of antifibrotic and anti-inflammatory treatment in CKD.
Vascular Calcification
S100A12 in Vascular Smooth Muscle Accelerates Vascular Calcification in Apolipoprotein E-Null Mice by Activating an Osteogenic Gene Regulatory Program.
Vascular Diseases
Adventitial application of the NADPH oxidase inhibitor apocynin in vivo reduces neointima formation and endothelial dysfunction in rabbits.
Vascular Diseases
Aging-associated metabolic disorder induces Nox2 activation and oxidative damage of endothelial function.
Vascular Diseases
An oxidized extracellular oxidation-reduction state increases Nox1 expression and proliferation in vascular smooth muscle cells via epidermal growth factor receptor activation.
Vascular Diseases
Annexin peptide Ac2-26 suppresses TNF?-induced inflammatory responses via inhibition of Rac1-dependent NADPH oxidase in human endothelial cells.
Vascular Diseases
AP-1-dependent transcriptional regulation of NADPH oxidase in human aortic smooth muscle cells: role of p22phox subunit.
Vascular Diseases
Cross-talk between mitochondria and NADPH oxidase: Effects of mild mitochondrial dysfunction on angiotensin II mediated increase in Nox isoform expression and activity in vascular smooth muscle cells.
Vascular Diseases
Cross-Talk Between Mitochondria and NADPH Oxidase: Effects of Mild Mitochondrial Dysfunction on Angiotensin II-Mediated Increase in Nox Isoform Expression and Activity in Vascular Smooth Muscle Cells.
Vascular Diseases
Differential effects of diabetes on the expression of the gp91phox homologues nox1 and nox4.
Vascular Diseases
Docosahexaenoic acid improves the nitroso-redox balance and reduces VEGF mediated angiogenic signaling in microvascular endothelial cells.
Vascular Diseases
Early increase of Nox4 NADPH oxidase and superoxide generation following endothelin-1-induced stroke in conscious rats.
Vascular Diseases
Endothelin-1 but not angiotensin II contributes to functional aging in murine carotid arteries.
Vascular Diseases
JAK/STAT Signaling Pathway Regulates Nox1 and Nox4-Based NADPH Oxidase in Human Aortic Smooth Muscle Cells.
Vascular Diseases
NAD(P)H oxidase isoforms as therapeutic targets for diabetic complications.
Vascular Diseases
Nitric oxide suppresses NADPH oxidase-dependent superoxide production by S-nitrosylation in human endothelial cells.
Vascular Diseases
Novel isoforms of NADPH oxidase in vascular physiology and pathophysiology.
Vascular Diseases
Novel role of protein disulfide isomerase in the regulation of NADPH oxidase activity: pathophysiological implications in vascular diseases.
Vascular Diseases
p22phox promotes Ang-II-induced vascular smooth muscle cell phenotypic switch by regulating KLF4 expression.
Vascular Diseases
Quercetin Inhibited Endothelial Dysfunction and Atherosclerosis in Apolipoprotein E-Deficient Mice: Critical Roles for NADPH Oxidase and Heme Oxygenase-1.
Vascular Diseases
Reactive oxygen species in the cerebral circulation: physiological roles and therapeutic implications for hypertension and stroke.
Vascular Diseases
Regulation of cell proliferation by NADPH oxidase-mediated signaling: Potential roles in tissue repair, regenerative medicine and tissue engineering.
Vascular Ring
2,3-cis-Procyanidins Elicit Endothelium-Dependent Relaxation in Porcine Coronary Arteries via Activation of the PI3/Akt Kinase Signaling Pathway.
Vascular System Injuries
"Angiotensin II memory" contributes to the development of hypertension and vascular injury via activation of NADPH oxidase.
Vascular System Injuries
Attenuation of aortic injury by ursolic acid through RAGE-Nox-NF?B pathway in streptozocin-induced diabetic rats.
Vascular System Injuries
NADPH oxidase in vascular injury: a new insight about its regulation and role in T cells.
Vascular System Injuries
NADPH oxidase, NOX1, mediates vascular injury in ischemic retinopathy.
Vascular System Injuries
OS 21-01 NOX1 OR NOX4 DELETION PREVENTS TYPE 1 DIABETES-INDUCED ENDOTHELIAL DYSFUNCTION.
Vascular System Injuries
Ox-LDL induces dysfunction of endothelial progenitor cells via activation of NF-?B.
Vascular System Injuries
Protective Role of Endogenous Kallistatin in Vascular Injury and Senescence by Inhibiting Oxidative Stress and Inflammation.
Vascular System Injuries
Vascular injury in diabetic db/db mice is ameliorated by atorvastatin: role of Rac1/2-sensitive Nox-dependent pathways.
Vasculitis
Immune system-mediated endothelial damage is associated with NO and antioxidant system disorders.
Vasospasm, Intracranial
Inhibition of NADPH oxidase attenuates vasospasm after experimental subarachnoid hemorrhage in rats.
Ventricular Dysfunction, Left
NADPH oxidase contributes to the left ventricular dysfunction induced by sinoaortic denervation in rats.
Ventricular Dysfunction, Left
Statins ameliorate pulmonary hypertension secondary to left ventricular dysfunction through the Rho-kinase pathway and NADPH oxidase.
Virus Diseases
Double-stranded RNA-induced dopaminergic neuronal loss in the substantia nigra in the presence of Mac1 receptor.
Virus Diseases
NADPH Oxidase 1 Is Associated with Altered Host Survival and T Cell Phenotypes after Influenza A Virus Infection in Mice.
Virus Diseases
Nox4-dependent ROS production is involved in CVB3-induced myocardial apoptosis.
Virus Diseases
Oxidative damage to neurons caused by the induction of microglial NADPH oxidase in encephalomyocarditis virus infection.
Virus Diseases
Pathogenic Effects of IFIT2 and Interferon-? during Fatal Systemic Candida albicans Infection.
Virus Diseases
Superoxide production by plant homologues of the gp91(phox) NADPH oxidase. Modulation of activity by calcium and by tobacco mosaic virus infection.
Virus Diseases
The metabolic and phagocytic activities of leukocytes from patients receiving corticosteroid and radiation therapy, and patients with bacterial infections.
Vitamin B 6 Deficiency
Effect of riboflavin or pyridoxine deficiency on inflammatory response.
Vitamin D Deficiency
Vitamin D Deficiency Aggravates Hepatic Oxidative Stress and Inflammation during Chronic Alcohol-Induced Liver Injury in Mice.
Vitamin E Deficiency
The effect of dietary vitamin E and beta-carotene on oxidation processes in the rat testis.
Vitiligo
In vivo and in vitro evidence for hydrogen peroxide (H2O2) accumulation in the epidermis of patients with vitiligo and its successful removal by a UVB-activated pseudocatalase.
Whooping Cough
A leading role for NADPH oxidase in an in-vitro study of experimental autoimmune encephalomyelitis.
Whooping Cough
Activation of NADPH oxidase by purine and pyrimidine nucleotides involves G proteins and is potentiated by chemotactic peptides.
Whooping Cough
Activation of natriuretic peptide receptor-C attenuates the enhanced oxidative stress in vascular smooth muscle cells from spontaneously hypertensive rats: implication of Gialpha protein.
Whooping Cough
Activation of the superoxide-generating NADPH oxidase of macrophages by sodium dodecyl sulfate in a soluble cell-free system: evidence for involvement of a G protein.
Whooping Cough
ATP and guanine nucleotide dependence of neutrophil activation. Evidence for the involvement of two distinct GTP-binding proteins.
Whooping Cough
cAMP-dependent inhibition is dominant in regulating superoxide production in the bone-resorbing osteoclasts.
Whooping Cough
Concanavalin A stimulation of O2 consumption in electropermeabilized neutrophils via a pertussis toxin-insensitive G protein.
Whooping Cough
Leukotriene B4 activates the NADPH oxidase in eosinophils by a pertussis toxin-sensitive mechanism that is largely independent of arachidonic acid mobilization.
Whooping Cough
Regulation of neutrophil NADPH oxidase activation in a cell-free system by guanine nucleotides and fluoride. Evidence for participation of a pertussis and cholera toxin-insensitive G protein.
Whooping Cough
Resolution of a low molecular weight G protein in neutrophil cytosol required for NADPH oxidase activation and reconstitution by recombinant Krev-1 protein.
Whooping Cough
Role of PKC-? in NADPH oxidase-PKC?-Gi? axis dependent inhibition of ?-adrenergic response by U46619 in pulmonary artery smooth muscle cells.
Whooping Cough
Role of PKC?-NADPH oxidase signaling axis in PKC?-mediated Gi?2 phosphorylation for inhibition of adenylate cyclase activity by angiotensin II in pulmonary artery smooth muscle cells.
Whooping Cough
Subcellular distribution and membrane association of human neutrophil substrates for ADP-ribosylation by pertussis toxin and cholera toxin.
[histone h3]-lysine9 n-trimethyltransferase deficiency
The Histone Methyltransferase SETDB1 Modulates Survival of Spermatogonial Stem/Progenitor Cells Through NADPH Oxidase.
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