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Information on EC 1.6.3.3 - NADH oxidase (H2O2-forming)

for references in articles please use BRENDA:EC1.6.3.3

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IUBMB Comments

A flavoprotein (FAD). The bacterium Streptococcus mutans contains two distinct NADH oxidases, a H2O2-forming enzyme and a H2O-forming enzyme (cf. EC 1.6.3.4, NADH oxidase (H2O-forming)) . The enzymes from the anaerobic archaea Methanocaldococcus jannaschii and Pyrococcus furiosus also produce low amounts of H2O. Unlike EC 1.6.3.1 (NAD(P)H oxidase) it has no activity towards NADPH.

The expected taxonomic range for this enzyme is: Archaea, Bacteria, Eukaryota
Reaction Schemes
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Synonyms
nox-1, noxb-1, noxa-1, noxa2, mj0649, h2o2-forming nadh oxidase, mjnox, af0395, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
NADH + H+ + O2 = NAD+ + H2O2
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS