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Information on EC 1.5.98.3 - coenzyme F420:methanophenazine dehydrogenase

for references in articles please use BRENDA:EC1.5.98.3

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IUBMB Comments

The enzyme, found in some methanogenic archaea, is responsible for the reoxidation of coenzyme F420, which is reduced during methanogenesis, and for the reduction of methanophenazine to dihydromethanophenazine, which is required by EC 1.8.98.1, dihydromethanophenazine:CoB-CoM heterodisulfide reductase. The enzyme is membrane-bound, and is coupled to proton translocation across the cytoplasmic membrane, generating a proton motive force that is used for ATP generation.

The enzyme appears in viruses and cellular organisms

Synonyms
f420h2-dehydrogenase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
reduced coenzyme F420 + methanophenazine = oxidized coenzyme F420 + dihydromethanophenazine
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
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Highest Expressing Human Cell Lines
Cell Line Links Gene Links