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Information on EC 1.5.1.52 - staphylopine dehydrogenase

for references in articles please use BRENDA:EC1.5.1.52

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IUBMB Comments

The enzyme, characterized from the bacterium Staphylococcus aureus, catalyses the last reaction in the biosynthesis of the metallophore staphylopine, which is involved in the acquisition of nickel, copper, and cobalt.

The enzyme appears in viruses and cellular organisms

Synonyms
saodh, staphylopine dehydrogenase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
staphylopine + NADP+ + H2O = (2S)-2-amino-4-{[(1R)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate + pyruvate + NADPH + H+
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
MetaCyc
staphylopine biosynthesis
Highest Expressing Human Cell Lines
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