Any feedback?
No. of entries
Information on EC 1.5.1.2 - pyrroline-5-carboxylate reductase
for references in articles please use BRENDA:EC1.5.1.2
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree 1 Oxidoreductases
1.5 Acting on the CH-NH group of donors
1.5.1 With NAD+ or NADP+ as acceptor
1.5.1.2 pyrroline-5-carboxylate reductase
IUBMB Comments
Also reduces 1-pyrroline-3-hydroxy-5-carboxylate to L-hydroxyproline.
The enzyme appears in viruses and cellular organisms
showSynonyms
pycr1, proline oxidase, pyrroline-5-carboxylate reductase, p5cr, p5c reductase, 1-pyrroline-5-carboxylate reductase, delta1-pyrroline-5-carboxylate reductase, l-proline oxidase, more
topPlease wait a moment until the data is sorted. This message will disappear when the data is sorted.
SYNONYM 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
1-pyrroline-5-carboxylate reductase
-
-
-
-
DELTA1-pyrroline-5-carboxylate reductase
L-proline oxidase
-
-
-
-
L-proline-NAD(P)+ 5-oxidoreductase
-
-
-
-
L-proline:NAD(P)+ 5-oxidoreductase
-
-
-
-
NADPH-L-DELTA'-pyrroline carboxylic acid reductase
-
-
-
-
P5C reductase
P5CR
PROC
proline oxidase
Pycr1
pyrroline-5-carboxylate reductase
reductase, pyrroline-5-carboxylate
-
-
-
-
TcCLB.509207.90
P5C reductase
-
-
-
-
P5CR
-
-
-
-
proline oxidase
-
-
-
-
pyrroline-5-carboxylate reductase
-
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT
LITERATURE
L-proline + NAD(P)+ = 1-pyrroline-5-carboxylate + NAD(P)H + H+
-
-
-
-
L-proline + NAD(P)+ = 1-pyrroline-5-carboxylate + NAD(P)H + H+
enzyme PYCR2 kinetics suggest a sequential binding mechanism with L-P5C binding before NAD(P)H and NAD(P)+ releasing before L-Pro
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
oxidation
redox reaction
reduction
oxidation
-
-
-
-
redox reaction
-
-
-
-
reduction
-
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
PATHWAY SOURCE
PATHWAYS
BRENDA
MetaCyc
L-arginine degradation VI (arginase 2 pathway), L-arginine degradation XIII (reductive Stickland reaction), L-proline biosynthesis I (from L-glutamate), L-proline biosynthesis III (from L-ornithine)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
SYSTEMATIC NAME
IUBMB Comments
L-proline:NAD(P)+ 5-oxidoreductase
Also reduces 1-pyrroline-3-hydroxy-5-carboxylate to L-hydroxyproline.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
CAS REGISTRY NUMBER
COMMENTARY
9029-17-8
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
SUBSTRATE
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
LITERATURE
COMMENTARY
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
1-pyrroline-3-hydroxy-5-carboxylate + NAD(P)H
L-hydroxyproline + NAD(P)+
-
Substrates: -
Products: -
Products: -
ir
1-pyrroline-5-carboxylate + NADH
L-proline + NAD+
Substrates: -
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NADPH
L-proline + NADP+
Substrates: -
Products: -
Products: -
?
DELTA1-piperideine-6-carboxylate + NADPH
L-pipecolic acid + NADP+
-
Substrates: -
Products: -
Products: -
ir
DELTA1-pyrroline-5-carboxylate + NADH + H+
L-proline + NAD+
Substrates: -
Products: -
Products: -
r
L-pipecolate + NAD+
DELTA1-piperideine 6-carboxylate + NADH + H+
Substrates: -
Products: -
Products: -
?
L-pipecolate + NADP+
DELTA1-piperideine 6-carboxylate + NADPH + H+
Substrates: -
Products: -
Products: -
?
L-Pro + NAD(P)+
1-pyrroline-5-carboxylate + NAD(P)H
-
Substrates: the enzyme plays a role as a downstream effector in p53-mediated apoptosis of renal carcinoma cells
Products: -
Products: -
?
L-Pro + NAD+
1-pyrroline-5-carboxylate + NADH
-
Substrates: -
Products: -
Products: -
?
L-Pro + NADP+
1-pyrroline-5-carboxylate + NADPH
-
Substrates: -
Products: -
Products: -
?
L-proline benzyl ester + NAD+
L-pyrroline-5-carboxy benzyl ester + NADH
-
Substrates: 24% of activity with proline
Products: -
Products: -
?
L-proline methyl ester + NAD+
1-pyrroline-5-carboxy methyl ester + NADH
-
Substrates: 16% of activity with proline
Products: -
Products: -
?
L-proline t-butyl ester + NAD+
1-pyrroline-5-carboxy tert-butylester + NADH
-
Substrates: 10% of activity with proline
Products: -
Products: -
?
piperideine-6-carboxylate + NADH + H+
L-pipecolic acid + NAD+
-
Substrates: -
Products: L-pipecolic acid is the sole product
Products: L-pipecolic acid is the sole product
ir
piperideine-6-carboxylate + NADPH + H+
L-pipecolic acid + NADP+
-
Substrates: -
Products: L-pipecolic acid is the sole product
Products: L-pipecolic acid is the sole product
ir
additional information
?
-
-
Substrates: not: D-proline, L-hydroxyproline, L-azatidine-2-carboxylate, no other amino acids
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NAD(P)H
L-proline + NAD(P)+
Substrates: -
Products: -
Products: -
r
1-pyrroline-5-carboxylate + NAD(P)H
L-proline + NAD(P)+
Substrates: -
Products: -
Products: -
r
1-pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: reversible at pH values above 8 and higher substrate concentrations, oxidation of L-proline is strictly specific for the L-isomer
Products: -
Products: -
r
1-pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: -
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: -
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: -
Products: -
Products: -
ir
1-pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: specific for L-isomer
Products: -
Products: -
ir
1-pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: -
Products: -
Products: -
ir
1-pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: -
Products: -
Products: -
ir
1-pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: specific for L-isomer
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: reaction is irreversible at pH 7.4, but reversible at pH 10.3
Products: -
Products: -
r
1-pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: -
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: -
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: -
Products: -
Products: -
ir
1-pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: specific for L-isomer
Products: -
Products: -
ir
1-pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: -
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: -
Products: -
Products: -
ir
1-pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: -
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: -
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: -
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: specific for L-isomer
Products: -
Products: -
ir
1-pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: -
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: specific for L-isomer
Products: -
Products: -
ir
1-pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: transfers the proS hydrogen at C-4 of the dihydropyridine ring of NAD(P)H to its substrate
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: -
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: -
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: -
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: -
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: -
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NADH + H+
L-proline + NAD+
-
Substrates: -
Products: -
Products: -
r
1-pyrroline-5-carboxylate + NADH + H+
L-proline + NAD+
-
Substrates: -
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NADH + H+
L-proline + NAD+
Substrates: -
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NADH + H+
L-proline + NAD+
-
Substrates: -
Products: -
Products: -
r
1-pyrroline-5-carboxylate + NADH + H+
L-proline + NAD+
-
Substrates: -
Products: -
Products: -
r
1-pyrroline-5-carboxylate + NADH + H+
L-proline + NAD+
-
Substrates: -
Products: -
Products: -
r
1-pyrroline-5-carboxylate + NADH + H+
L-proline + NAD+
-
Substrates: -
Products: -
Products: -
r
1-pyrroline-5-carboxylate + NADH + H+
L-proline + NAD+
-
Substrates: -
Products: -
Products: -
r
1-pyrroline-5-carboxylate + NADH + H+
L-proline + NAD+
-
Substrates: -
Products: -
Products: -
r
1-pyrroline-5-carboxylate + NADH + H+
L-proline + NAD+
-
Substrates: -
Products: -
Products: -
r
1-pyrroline-5-carboxylate + NADH + H+
L-proline + NAD+
-
Substrates: -
Products: -
Products: -
r
1-pyrroline-5-carboxylate + NADH + H+
L-proline + NAD+
Substrates: -
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NADH + H+
L-proline + NAD+
-
Substrates: -
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NADH + H+
L-proline + NAD+
Substrates: -
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NADH + H+
L-proline + NAD+
Substrates: -
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NADH + H+
L-proline + NAD+
-
Substrates: -
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NADH + H+
L-proline + NAD+
Substrates: -
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NADH + H+
L-proline + NAD+
-
Substrates: -
Products: -
Products: -
r
1-pyrroline-5-carboxylate + NADH + H+
L-proline + NAD+
-
Substrates: -
Products: -
Products: -
r
1-pyrroline-5-carboxylate + NADH + H+
L-proline + NAD+
-
Substrates: -
Products: -
Products: -
r
1-pyrroline-5-carboxylate + NADH + H+
L-proline + NAD+
-
Substrates: -
Products: -
Products: -
r
1-pyrroline-5-carboxylate + NADH + H+
L-proline + NAD+
-
Substrates: -
Products: -
Products: -
r
1-pyrroline-5-carboxylate + NADH + H+
L-proline + NAD+
-
Substrates: -
Products: -
Products: -
r
1-pyrroline-5-carboxylate + NADH + H+
L-proline + NAD+
-
Substrates: -
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NADH + H+
L-proline + NAD+
-
Substrates: -
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NADH + H+
L-proline + NAD+
-
Substrates: -
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NADH + H+
L-proline + NAD+
Substrates: -
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NADH + H+
L-proline + NAD+
Substrates: -
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NADPH + H+
L-proline + NADP+
Substrates: -
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NADPH + H+
L-proline + NADP+
-
Substrates: -
Products: -
Products: -
r
1-pyrroline-5-carboxylate + NADPH + H+
L-proline + NADP+
-
Substrates: -
Products: -
Products: -
r
1-pyrroline-5-carboxylate + NADPH + H+
L-proline + NADP+
-
Substrates: -
Products: -
Products: -
r
1-pyrroline-5-carboxylate + NADPH + H+
L-proline + NADP+
Substrates: -
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NADPH + H+
L-proline + NADP+
-
Substrates: -
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NADPH + H+
L-proline + NADP+
Substrates: -
Products: -
Products: -
r
1-pyrroline-5-carboxylate + NADPH + H+
L-proline + NADP+
Substrates: -
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NADPH + H+
L-proline + NADP+
-
Substrates: -
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NADPH + H+
L-proline + NADP+
Substrates: -
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NADPH + H+
L-proline + NADP+
-
Substrates: -
Products: -
Products: -
r
1-pyrroline-5-carboxylate + NADPH + H+
L-proline + NADP+
-
Substrates: activity assay, forward reaction
Products: -
Products: -
r
1-pyrroline-5-carboxylate + NADPH + H+
L-proline + NADP+
-
Substrates: -
Products: -
Products: -
r
1-pyrroline-5-carboxylate + NADPH + H+
L-proline + NADP+
-
Substrates: -
Products: -
Products: -
r
1-pyrroline-5-carboxylate + NADPH + H+
L-proline + NADP+
-
Substrates: -
Products: -
Products: -
r
1-pyrroline-5-carboxylate + NADPH + H+
L-proline + NADP+
-
Substrates: -
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NADPH + H+
L-proline + NADP+
Substrates: -
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NADPH + H+
L-proline + NADP+
Substrates: -
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NADPH + H+
L-proline + NADP+
Substrates: -
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NADPH + H+
L-proline + NADP+
Substrates: -
Products: -
Products: -
?
L-proline + NAD(P)+
1-pyrroline-5-carboxylate + NAD(P)H
Substrates: -
Products: -
Products: -
r
L-proline + NAD(P)+
1-pyrroline-5-carboxylate + NAD(P)H
Substrates: -
Products: -
Products: -
r
L-proline + NAD(P)+
1-pyrroline-5-carboxylate + NAD(P)H + H+
-
Substrates: -
Products: -
Products: -
r
L-proline + NAD(P)+
1-pyrroline-5-carboxylate + NAD(P)H + H+
-
Substrates: -
Products: -
Products: -
r
L-proline + NAD(P)+
1-pyrroline-5-carboxylate + NAD(P)H + H+
-
Substrates: first step in proline metabolism the hepatocyte nuclear factors HNF4alpha and HNF1alpüha regulate proline metabolism in adult liver
Products: -
Products: -
?
L-proline + NAD+
1-pyrroline-5-carboxylate + NADH + H+
-
Substrates: -
Products: -
Products: -
r
L-proline + NAD+
1-pyrroline-5-carboxylate + NADH + H+
-
Substrates: -
Products: -
Products: -
r
L-proline + NADP+
1-pyrroline-5-carboxylate + NADPH + H+
-
Substrates: -
Products: -
Products: -
r
L-proline + NADP+
1-pyrroline-5-carboxylate + NADPH + H+
-
Substrates: -
Products: -
Products: -
r
L-thioproline + NAD(P)+
1-pyrroline-3-thio-5-carboxylate + NAD(P)H
Substrates: -
Products: -
Products: -
r
L-thioproline + NAD(P)+
1-pyrroline-3-thio-5-carboxylate + NAD(P)H
Substrates: -
Products: -
Products: -
r
pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: discussion of role in vivo
Products: -
Products: -
?
pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: discussion of role in vivo
Products: -
Products: -
?
pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: discussion of role in vivo
Products: -
Products: -
?
pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: ping pong mechanism
Products: -
Products: -
?
pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: discussion of role in vivo
Products: -
Products: -
?
pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: ping pong mechanism
Products: -
Products: -
?
pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: -
Products: -
Products: -
?
pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: -
Products: -
Products: -
?
pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: discussion of role in vivo
Products: -
Products: -
?
pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: transfer of reducing equivalents from host plants to symbiotic partner
Products: -
Products: -
?
pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: third enzyme in proline pathway
Products: -
Products: -
?
pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: linkage to hexose monophosphate pathway
Products: -
Products: -
?
pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: discussion of role in vivo
Products: -
Products: -
?
pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: discussion of role in vivo
Products: -
Products: -
?
pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: discussion of role in vivo
Products: -
Products: -
?
pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: final reaction of proline synthesis
Products: -
Products: -
?
pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: discussion of role in vivo
Products: -
Products: -
?
pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: -
Products: -
Products: -
?
pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: transfer of reducing equivalents into mitochondria, linkage to pentose phosphate pathway
Products: -
Products: -
?
pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: discussion of role in vivo
Products: -
Products: -
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
LITERATURE
COMMENTARY
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
DELTA1-pyrroline-5-carboxylate + NADH + H+
L-proline + NAD+
Substrates: -
Products: -
Products: -
r
L-pipecolate + NAD+
DELTA1-piperideine 6-carboxylate + NADH + H+
Substrates: -
Products: -
Products: -
?
L-pipecolate + NADP+
DELTA1-piperideine 6-carboxylate + NADPH + H+
Substrates: -
Products: -
Products: -
?
L-Pro + NAD(P)+
1-pyrroline-5-carboxylate + NAD(P)H
-
Substrates: the enzyme plays a role as a downstream effector in p53-mediated apoptosis of renal carcinoma cells
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: -
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: -
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NADH + H+
L-proline + NAD+
Substrates: -
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NADH + H+
L-proline + NAD+
-
Substrates: -
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NADPH + H+
L-proline + NADP+
Substrates: -
Products: -
Products: -
r
1-pyrroline-5-carboxylate + NADPH + H+
L-proline + NADP+
Substrates: -
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NADPH + H+
L-proline + NADP+
-
Substrates: -
Products: -
Products: -
?
1-pyrroline-5-carboxylate + NADPH + H+
L-proline + NADP+
-
Substrates: -
Products: -
Products: -
r
L-proline + NAD(P)+
1-pyrroline-5-carboxylate + NAD(P)H + H+
-
Substrates: -
Products: -
Products: -
r
L-proline + NAD(P)+
1-pyrroline-5-carboxylate + NAD(P)H + H+
-
Substrates: first step in proline metabolism the hepatocyte nuclear factors HNF4alpha and HNF1alpüha regulate proline metabolism in adult liver
Products: -
Products: -
?
L-proline + NADP+
1-pyrroline-5-carboxylate + NADPH + H+
-
Substrates: -
Products: -
Products: -
r
L-proline + NADP+
1-pyrroline-5-carboxylate + NADPH + H+
-
Substrates: -
Products: -
Products: -
r
pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: discussion of role in vivo
Products: -
Products: -
?
pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: discussion of role in vivo
Products: -
Products: -
?
pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: discussion of role in vivo
Products: -
Products: -
?
pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: ping pong mechanism
Products: -
Products: -
?
pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: discussion of role in vivo
Products: -
Products: -
?
pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: ping pong mechanism
Products: -
Products: -
?
pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: -
Products: -
Products: -
?
pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: discussion of role in vivo
Products: -
Products: -
?
pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: transfer of reducing equivalents from host plants to symbiotic partner
Products: -
Products: -
?
pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: third enzyme in proline pathway
Products: -
Products: -
?
pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: linkage to hexose monophosphate pathway
Products: -
Products: -
?
pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: discussion of role in vivo
Products: -
Products: -
?
pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: discussion of role in vivo
Products: -
Products: -
?
pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: discussion of role in vivo
Products: -
Products: -
?
pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: final reaction of proline synthesis
Products: -
Products: -
?
pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: discussion of role in vivo
Products: -
Products: -
?
pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: -
Products: -
Products: -
?
pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: transfer of reducing equivalents into mitochondria, linkage to pentose phosphate pathway
Products: -
Products: -
?
pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
-
Substrates: discussion of role in vivo
Products: -
Products: -
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
COFACTOR
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
NAD+
2fold preference for NADP+ with apparent KM 0.172 mM over NAD+ with apparent KM 0.3896 mM