Disease on EC 1.5.1.1 - 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase [NAD(P)H]
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Adenocarcinoma
Pyrroline-5-Carboxylate Reductase-2 Promotes Colorectal Cancer Progression via Activating PI3K/AKT/mTOR Pathway.
African Swine Fever
African Swine Fever Virus Protein E199L Promotes Cell Autophagy through the Interaction of PYCR2.
Brain Diseases
Loss of PYCR2 Causes Neurodegeneration by Increasing Cerebral Glycine Levels via SHMT2.
Carcinogenesis
Pyrroline-5-Carboxylate Reductase-2 Promotes Colorectal Cancer Progression via Activating PI3K/AKT/mTOR Pathway.
Carcinoma, Hepatocellular
Molecular cloning of cDNA encoding a 55-kDa multifunctional thyroid hormone binding protein of skeletal muscle sarcoplasmic reticulum.
Carcinoma, Hepatocellular
The upregulation of PYCR2 is associated with aggressive colon cancer progression and a poor prognosis.
Carcinoma, Squamous Cell
An in vitro novel mechanism of regulating the activity of pyruvate kinase M2 by thyroid hormone and fructose 1, 6-bisphosphate.
Carcinoma, Squamous Cell
Characterization of a membrane-associated 3,3',5-triiodo-L-thyronine binding protein by use of monoclonal antibodies.
Choriocarcinoma
Regulation of thyroid hormone receptor-mediated transcription by a cytosol protein.
Colonic Neoplasms
The upregulation of PYCR2 is associated with aggressive colon cancer progression and a poor prognosis.
Deafness
CRYM mutations cause deafness through thyroid hormone binding properties in the fibrocytes of the cochlea.
Deafness
Spiking Expression of mu-Crystallin mRNA during Treatment with Methimazole in Patients with Graves' Hyperthyroidism.
Hearing Loss
CRYM mutations cause deafness through thyroid hormone binding properties in the fibrocytes of the cochlea.
Hyperglycemia
Hyperglycemia induces elevated expression of thyroid hormone binding protein in vivo in kidney and heart and in vitro in mesangial cells.
Hyperglycemia
Loss of PYCR2 Causes Neurodegeneration by Increasing Cerebral Glycine Levels via SHMT2.
Hyperkinesis
PYCR2 Mutations cause a lethal syndrome of microcephaly and failure to thrive.
Hypersensitivity
PYCR1 and PYCR2 Interact and Collaborate with RRM2B to Protect Cells from Overt Oxidative Stress.
Hyperthyroidism
Concentration of serum thyroid hormone binding proteins after 131I treatment of hyperthyroidism.
Hyperthyroidism
Measurement of serum thyroxine binding prealbumin in various thyroidal states by radioimmunoassay.
Hyperthyroidism
Spiking Expression of mu-Crystallin mRNA during Treatment with Methimazole in Patients with Graves' Hyperthyroidism.
Hyperthyroidism
[Improved thyroid diagnosis in borderline hyperthyroidism by determination of free T3 index]
Infections
African Swine Fever Virus Protein E199L Promotes Cell Autophagy through the Interaction of PYCR2.
Melanoma
Downregulation of pyrroline-5-carboxylate reductase-2 induces the autophagy of melanoma cells via AMPK/mTOR pathway.
Melanoma
The upregulation of PYCR2 is associated with aggressive colon cancer progression and a poor prognosis.
Microcephaly
Expanding the genotypic spectrum of PYCR2 and a common ancestry in Thai patients with hypomyelinating leukodystrophy 10.
Microcephaly
Loss of PYCR2 Causes Neurodegeneration by Increasing Cerebral Glycine Levels via SHMT2.
Microcephaly
Mutations in PYCR2, Encoding Pyrroline-5-Carboxylate Reductase 2, Cause Microcephaly and Hypomyelination.
Microcephaly
PYCR2 Mutations cause a lethal syndrome of microcephaly and failure to thrive.
Movement Disorders
Expanding the genotypic spectrum of PYCR2 and a common ancestry in Thai patients with hypomyelinating leukodystrophy 10.
Muscle Hypotonia
PYCR2 Mutations cause a lethal syndrome of microcephaly and failure to thrive.
Muscular Diseases
Abnormal expression of mu-crystallin in facioscapulohumeral muscular dystrophy.
Muscular Dystrophies
Abnormal expression of mu-crystallin in facioscapulohumeral muscular dystrophy.
Muscular Dystrophy, Facioscapulohumeral
Abnormal expression of mu-crystallin in facioscapulohumeral muscular dystrophy.
Neoplasm Metastasis
Pyrroline-5-Carboxylate Reductase-2 Promotes Colorectal Cancer Progression via Activating PI3K/AKT/mTOR Pathway.
Neoplasm Metastasis
The upregulation of PYCR2 is associated with aggressive colon cancer progression and a poor prognosis.
Neoplasms
Moderate-Intensity Exercise Induces Neurogenesis and Improves Cognition in Old Mice by Upregulating Hippocampal Hippocalcin, Otub1, and Spectrin-?.
Neoplasms
Pyrroline-5-Carboxylate Reductase-2 Promotes Colorectal Cancer Progression via Activating PI3K/AKT/mTOR Pathway.
Neoplasms
The upregulation of PYCR2 is associated with aggressive colon cancer progression and a poor prognosis.
Paraplegia
Spastic paraplegia as the only symptom in two adult-onset patients carrying a novel pathogenic variant in PYCR2.
Spinal Cord Injuries
Comprehensive Corticospinal Labeling with mu-crystallin Transgene Reveals Axon Regeneration after Spinal Cord Trauma in ngr1-/- Mice.
Uterine Cervical Neoplasms
Identification of potential cervical cancer serum biomarkers in Thai patients.
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