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Disease on EC 1.5.1.1 - 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase [NAD(P)H]

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Adenocarcinoma
Pyrroline-5-Carboxylate Reductase-2 Promotes Colorectal Cancer Progression via Activating PI3K/AKT/mTOR Pathway.
African Swine Fever
African Swine Fever Virus Protein E199L Promotes Cell Autophagy through the Interaction of PYCR2.
Brain Diseases
Loss of PYCR2 Causes Neurodegeneration by Increasing Cerebral Glycine Levels via SHMT2.
Carcinogenesis
Pyrroline-5-Carboxylate Reductase-2 Promotes Colorectal Cancer Progression via Activating PI3K/AKT/mTOR Pathway.
Carcinoma, Hepatocellular
Molecular cloning of cDNA encoding a 55-kDa multifunctional thyroid hormone binding protein of skeletal muscle sarcoplasmic reticulum.
The upregulation of PYCR2 is associated with aggressive colon cancer progression and a poor prognosis.
Carcinoma, Squamous Cell
An in vitro novel mechanism of regulating the activity of pyruvate kinase M2 by thyroid hormone and fructose 1, 6-bisphosphate.
Characterization of a membrane-associated 3,3',5-triiodo-L-thyronine binding protein by use of monoclonal antibodies.
Choriocarcinoma
Regulation of thyroid hormone receptor-mediated transcription by a cytosol protein.
Colonic Neoplasms
The upregulation of PYCR2 is associated with aggressive colon cancer progression and a poor prognosis.
Cutis Laxa
Genetic analysis of Pycr1 and Pycr2 in mice.
Deafness
CRYM mutations cause deafness through thyroid hormone binding properties in the fibrocytes of the cochlea.
mu-crystallin, a NADPH-dependent T(3)-binding protein in cytosol.
Spiking Expression of mu-Crystallin mRNA during Treatment with Methimazole in Patients with Graves' Hyperthyroidism.
Glioblastoma
Biomarker discovery: a proteomic approach for brain cancer profiling.
Hearing Loss
CRYM mutations cause deafness through thyroid hormone binding properties in the fibrocytes of the cochlea.
Hepatitis
Thyroid hormone binding protein in chronic active hepatitis.
Hepatitis, Chronic
Thyroid hormone binding protein in chronic active hepatitis.
Hyperglycemia
Hyperglycemia induces elevated expression of thyroid hormone binding protein in vivo in kidney and heart and in vitro in mesangial cells.
Loss of PYCR2 Causes Neurodegeneration by Increasing Cerebral Glycine Levels via SHMT2.
Hyperkinesis
PYCR2 Mutations cause a lethal syndrome of microcephaly and failure to thrive.
Hypersensitivity
PYCR1 and PYCR2 Interact and Collaborate with RRM2B to Protect Cells from Overt Oxidative Stress.
Hyperthyroidism
Concentration of serum thyroid hormone binding proteins after 131I treatment of hyperthyroidism.
Measurement of serum thyroxine binding prealbumin in various thyroidal states by radioimmunoassay.
Spiking Expression of mu-Crystallin mRNA during Treatment with Methimazole in Patients with Graves' Hyperthyroidism.
[Improved thyroid diagnosis in borderline hyperthyroidism by determination of free T3 index]
Infections
African Swine Fever Virus Protein E199L Promotes Cell Autophagy through the Interaction of PYCR2.
Kyphosis
Genetic analysis of Pycr1 and Pycr2 in mice.
Melanoma
Downregulation of pyrroline-5-carboxylate reductase-2 induces the autophagy of melanoma cells via AMPK/mTOR pathway.
The upregulation of PYCR2 is associated with aggressive colon cancer progression and a poor prognosis.
Microcephaly
Disease variants of human ?1-pyrroline-5-carboxylate reductase 2 (PYCR2).
Expanding the genotypic spectrum of PYCR2 and a common ancestry in Thai patients with hypomyelinating leukodystrophy 10.
Loss of PYCR2 Causes Neurodegeneration by Increasing Cerebral Glycine Levels via SHMT2.
Mutations in PYCR2, Encoding Pyrroline-5-Carboxylate Reductase 2, Cause Microcephaly and Hypomyelination.
PYCR2 Mutation Causing Hypomyelination and Microcephaly in an Indian Child.
PYCR2 Mutations cause a lethal syndrome of microcephaly and failure to thrive.
Movement Disorders
Expanding the genotypic spectrum of PYCR2 and a common ancestry in Thai patients with hypomyelinating leukodystrophy 10.
Muscle Hypotonia
PYCR2 Mutations cause a lethal syndrome of microcephaly and failure to thrive.
Muscular Diseases
Abnormal expression of mu-crystallin in facioscapulohumeral muscular dystrophy.
Muscular Dystrophies
Abnormal expression of mu-crystallin in facioscapulohumeral muscular dystrophy.
Muscular Dystrophy, Facioscapulohumeral
Abnormal expression of mu-crystallin in facioscapulohumeral muscular dystrophy.
Neoplasm Metastasis
Pyrroline-5-Carboxylate Reductase-2 Promotes Colorectal Cancer Progression via Activating PI3K/AKT/mTOR Pathway.
The upregulation of PYCR2 is associated with aggressive colon cancer progression and a poor prognosis.
Neoplasms
Moderate-Intensity Exercise Induces Neurogenesis and Improves Cognition in Old Mice by Upregulating Hippocampal Hippocalcin, Otub1, and Spectrin-?.
Pyrroline-5-Carboxylate Reductase-2 Promotes Colorectal Cancer Progression via Activating PI3K/AKT/mTOR Pathway.
The upregulation of PYCR2 is associated with aggressive colon cancer progression and a poor prognosis.
Paraplegia
Spastic paraplegia as the only symptom in two adult-onset patients carrying a novel pathogenic variant in PYCR2.
Spinal Cord Injuries
Comprehensive Corticospinal Labeling with mu-crystallin Transgene Reveals Axon Regeneration after Spinal Cord Trauma in ngr1-/- Mice.
Uterine Cervical Neoplasms
Identification of potential cervical cancer serum biomarkers in Thai patients.